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Physiologic Hyperinsulinemia Caused by Acute Hyperglycemia Minimizes Renal Sodium Loss by Direct Action on the Kidney.

Irsik DL, Brands MW.

Am J Physiol Regul Integr Comp Physiol. 2018 May 23. doi: 10.1152/ajpregu.00016.2018. [Epub ahead of print]


Laser-speckle imaging to measure tissue perfusion in free flaps in oral and maxillofacial surgery: a potentially exciting and easy to use monitoring method.

Brennan PA, Brands MT, Gush R, Alam P.

Br J Oral Maxillofac Surg. 2018 Jul;56(6):556-558. doi: 10.1016/j.bjoms.2018.03.023. Epub 2018 May 18. No abstract available.


Influence of prednisolone on parameters of de novo lipogenesis and indices for stearoyl-CoA- and Δ6- desaturase activity in healthy males: A Post-hoc analysis of a randomized, placebo-controlled, double-blind trial.

Pranger IG, van Raalte DH, Brands M, Muskiet MHA, Kema IP, Serlie MJ, Diamant M, Bakker SJL, Muskiet FAJ.

Prostaglandins Leukot Essent Fatty Acids. 2018 May;132:8-15. doi: 10.1016/j.plefa.2018.03.009. Epub 2018 Apr 3.


The osteoblast: Linking glucocorticoid-induced osteoporosis and hyperglycaemia? A post-hoc analysis of a randomised clinical trial.

van Bommel EJM, de Jongh RT, Brands M, Heijboer AC, den Heijer M, Serlie MJ, van Raalte DH.

Bone. 2018 Jul;112:173-176. doi: 10.1016/j.bone.2018.04.025. Epub 2018 May 3.


The Lotus japonicus acyl-acyl carrier protein thioesterase FatM is required for mycorrhiza formation and lipid accumulation of Rhizophagus irregularis.

Brands M, Wewer V, Keymer A, Gutjahr C, Dörmann P.

Plant J. 2018 Jul;95(2):219-232. doi: 10.1111/tpj.13943. Epub 2018 May 21.


Follow-up after curative treatment for oral squamous cell carcinoma. A critical appraisal of the guidelines and a review of the literature.

Brands MT, Brennan PA, Verbeek ALM, Merkx MAW, Geurts SME.

Eur J Surg Oncol. 2018 May;44(5):559-565. doi: 10.1016/j.ejso.2018.01.004. Epub 2018 Jan 12. Review.


Relevance of Orbital Interactions and Pauli Repulsion in the Metal-Metal Bond of Coinage Metals.

Brands MB, Nitsch J, Guerra CF.

Inorg Chem. 2018 Mar 5;57(5):2603-2608. doi: 10.1021/acs.inorgchem.7b02994. Epub 2018 Feb 12.


Correction: Diabetes-Induced Superoxide Anion and Breakdown of the Blood-Retinal Barrier: Role of the VEGF/uPAR Pathway.

El-Remessy AB, Franklin T, Ghaley N, Yang J, Brands MW, Caldwell RB, Behzadian MA.

PLoS One. 2017 Oct 16;12(10):e0186749. doi: 10.1371/journal.pone.0186749. eCollection 2017.


Should we be rethinking follow-up for oral cancer patients?

Brands MT, Merkx MAW, Geurts SME, Brennan PA.

J Oral Pathol Med. 2017 Oct;46(9):665-666. doi: 10.1111/jop.12596. No abstract available.


Chronic renal artery insulin infusion increases mean arterial pressure in male Sprague-Dawley rats.

Irsik DL, Chen JK, Brands MW.

Am J Physiol Renal Physiol. 2018 Jan 1;314(1):F81-F88. doi: 10.1152/ajprenal.00374.2017. Epub 2017 Sep 27.


Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer.

Lücking U, Scholz A, Lienau P, Siemeister G, Kosemund D, Bohlmann R, Briem H, Terebesi I, Meyer K, Prelle K, Denner K, Bömer U, Schäfer M, Eis K, Valencia R, Ince S, von Nussbaum F, Mumberg D, Ziegelbauer K, Klebl B, Choidas A, Nussbaumer P, Baumann M, Schultz-Fademrecht C, Rühter G, Eickhoff J, Brands M.

ChemMedChem. 2017 Nov 8;12(21):1776-1793. doi: 10.1002/cmdc.201700447. Epub 2017 Oct 16.


Intensity-modulated radiotherapy in head and neck cancer - an update for oral and maxillofacial surgeons.

Brennan PA, Bradley KL, Brands M.

Br J Oral Maxillofac Surg. 2017 Oct;55(8):770-774. doi: 10.1016/j.bjoms.2017.07.019. Epub 2017 Aug 26. Review.


Fasting and surgical performance: potential source of harm?

Brands MT, Hockey P, Sced A, Brennan PA.

Br J Oral Maxillofac Surg. 2017 Oct;55(8):755-756. doi: 10.1016/j.bjoms.2017.07.020. Epub 2017 Aug 23. No abstract available.


Cationic ionic liquid surfactant-polyacrylamide gel electrophoresis for enhanced separation of acidic and basic proteins with single-step ribonuclease b glycoforms separation.

Vidanapathirana P, Hasan F, Mussio K, Pande A, Brands M, Siraj N, Grove A, Warner IM.

J Chromatogr A. 2017 Sep 15;1515:245-251. doi: 10.1016/j.chroma.2017.07.083. Epub 2017 Jul 29.


Lipid transfer from plants to arbuscular mycorrhiza fungi.

Keymer A, Pimprikar P, Wewer V, Huber C, Brands M, Bucerius SL, Delaux PM, Klingl V, Röpenack-Lahaye EV, Wang TL, Eisenreich W, Dörmann P, Parniske M, Gutjahr C.

Elife. 2017 Jul 20;6. pii: e29107. doi: 10.7554/eLife.29107.


Surgical specimen handover from the operating theatre to laboratory-Can we improve patient safety by learning from aviation and other high-risk organisations?

Brennan PA, Brands MT, Caldwell L, Fonseca FP, Turley N, Foley S, Rahimi S.

J Oral Pathol Med. 2018 Feb;47(2):117-120. doi: 10.1111/jop.12614. Epub 2017 Aug 20.


Arbuscular mycorrhiza-specific enzymes FatM and RAM2 fine-tune lipid biosynthesis to promote development of arbuscular mycorrhiza.

Bravo A, Brands M, Wewer V, Dörmann P, Harrison MJ.

New Phytol. 2017 Jun;214(4):1631-1645. doi: 10.1111/nph.14533. Epub 2017 Apr 5.


The normal increase in insulin after a meal may be required to prevent postprandial renal sodium and volume losses.

Irsik DL, Blazer-Yost BL, Staruschenko A, Brands MW.

Am J Physiol Regul Integr Comp Physiol. 2017 Jun 1;312(6):R965-R972. doi: 10.1152/ajpregu.00354.2016. Epub 2017 Mar 22.


Discovery and SAR of Novel 2,3-Dihydroimidazo[1,2-c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80-6946).

Scott WJ, Hentemann MF, Rowley RB, Bull CO, Jenkins S, Bullion AM, Johnson J, Redman A, Robbins AH, Esler W, Fracasso RP, Garrison T, Hamilton M, Michels M, Wood JE, Wilkie DP, Xiao H, Levy J, Stasik E, Liu N, Schaefer M, Brands M, Lefranc J.

ChemMedChem. 2016 Jul 19;11(14):1517-30. doi: 10.1002/cmdc.201600148. Epub 2016 Jun 16.


Trends in oral cavity cancer incidence, mortality, survival and treatment in the Netherlands.

van Dijk BA, Brands MT, Geurts SM, Merkx MA, Roodenburg JL.

Int J Cancer. 2016 Aug 1;139(3):574-83. doi: 10.1002/ijc.30107. Epub 2016 Apr 18.


Lipids in plant-microbe interactions.

Siebers M, Brands M, Wewer V, Duan Y, Hölzl G, Dörmann P.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt B):1379-1395. doi: 10.1016/j.bbalip.2016.02.021. Epub 2016 Feb 27. Review.


Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity.

Wengner AM, Siemeister G, Koppitz M, Schulze V, Kosemund D, Klar U, Stoeckigt D, Neuhaus R, Lienau P, Bader B, Prechtl S, Raschke M, Frisk AL, von Ahsen O, Michels M, Kreft B, von Nussbaum F, Brands M, Mumberg D, Ziegelbauer K.

Mol Cancer Ther. 2016 Apr;15(4):583-92. doi: 10.1158/1535-7163.MCT-15-0500. Epub 2016 Feb 1.


BAY 1024767 blocks androgen receptor mutants found in castration-resistant prostate cancer patients.

Sugawara T, Lejeune P, Köhr S, Neuhaus R, Faus H, Gelato KA, Busemann M, Cleve A, Lücking U, von Nussbaum F, Brands M, Mumberg D, Jung K, Stephan C, Haendler B.

Oncotarget. 2016 Feb 2;7(5):6015-28. doi: 10.18632/oncotarget.6864.


Deletion of protein tyrosine phosphatase 1b in proopiomelanocortin neurons reduces neurogenic control of blood pressure and protects mice from leptin- and sympatho-mediated hypertension.

Bruder-Nascimento T, Butler BR, Herren DJ, Brands MW, Bence KK, Belin de Chantemèle EJ.

Pharmacol Res. 2015 Dec;102:235-44. doi: 10.1016/j.phrs.2015.10.012. Epub 2015 Oct 30.


The role of IL-6 in the physiologic versus hypertensive blood pressure actions of angiotensin II.

Manhiani MM, Seth DM, Banes-Berceli AK, Satou R, Navar LG, Brands MW.

Physiol Rep. 2015 Oct;3(10). pii: e12595. doi: 10.14814/phy2.12595.


Long-term cognitive follow-up in children treated for Maroteaux-Lamy syndrome.

Ebbink BJ, Brands MM, van den Hout JM, Lequin MH, Coebergh van den Braak RR, van de Weitgraven RL, Plug I, Aarsen FK, van der Ploeg AT.

J Inherit Metab Dis. 2016 Mar;39(2):285-92. doi: 10.1007/s10545-015-9895-8. Epub 2015 Oct 8.


Insulin resistance in obesity can be reliably identified from fasting plasma insulin.

ter Horst KW, Gilijamse PW, Koopman KE, de Weijer BA, Brands M, Kootte RS, Romijn JA, Ackermans MT, Nieuwdorp M, Soeters MR, Serlie MJ.

Int J Obes (Lond). 2015 Dec;39(12):1703-9. doi: 10.1038/ijo.2015.125. Epub 2015 Jul 9.


Deletion of UNC5B in Kidney Epithelium Exacerbates Diabetic Nephropathy in Mice.

Ranganathan P, Mohamed R, Jayakumar C, Brands MW, Ramesh G.

Am J Nephrol. 2015;41(3):220-30. doi: 10.1159/000381428. Epub 2015 Apr 16.


Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel.

Wilson PC, Fitzgibbon WR, Garrett SM, Jaffa AA, Luttrell LM, Brands MW, El-Shewy HM.

Mol Endocrinol. 2015 Jun;29(6):896-908. doi: 10.1210/me.2014-1388. Epub 2015 Apr 14.


Cross-talk between insulin and IGF-1 receptors in the cortical collecting duct principal cells: implication for ENaC-mediated Na+ reabsorption.

Ilatovskaya DV, Levchenko V, Brands MW, Pavlov TS, Staruschenko A.

Am J Physiol Renal Physiol. 2015 Apr 1;308(7):F713-9. doi: 10.1152/ajprenal.00081.2014. Epub 2015 Jan 28.


Limited rights of minors in the Dutch healthcare.

Brands W, Brands M, Brands-Bottema G.

J Forensic Odontostomatol. 2014 Nov 30;32 Suppl 1:30-3.


Urinary semaphorin 3A correlates with diabetic proteinuria and mediates diabetic nephropathy and associated inflammation in mice.

Mohamed R, Ranganathan P, Jayakumar C, Nauta FL, Gansevoort RT, Weintraub NL, Brands M, Ramesh G.

J Mol Med (Berl). 2014 Dec;92(12):1245-56. doi: 10.1007/s00109-014-1209-3. Epub 2014 Sep 25.


Pain: a prevalent feature in patients with mucopolysaccharidosis. Results of a cross-sectional national survey.

Brands MM, Güngör D, van den Hout JM, Karstens FP, Oussoren E, Plug I, Boelens JJ, van Hasselt PM, Hollak CE, Mulder MF, Rubio Gozalbo E, Smeitink JA, Smit GP, Wijburg FA, Meutgeert H, van der Ploeg AT.

J Inherit Metab Dis. 2015 Mar;38(2):323-31. doi: 10.1007/s10545-014-9737-0. Epub 2014 Jul 22.


Fatty acid synthesis and lipid metabolism in the obligate biotrophic fungus Rhizophagus irregularis during mycorrhization of Lotus japonicus.

Wewer V, Brands M, Dörmann P.

Plant J. 2014 Aug;79(3):398-412. doi: 10.1111/tpj.12566. Epub 2014 Jul 2.


l-Citrulline Protects from Kidney Damage in Type 1 Diabetic Mice.

Romero MJ, Yao L, Sridhar S, Bhatta A, Dou H, Ramesh G, Brands MW, Pollock DM, Caldwell RB, Cederbaum SD, Head CA, Bagi Z, Lucas R, Caldwell RW.

Front Immunol. 2013 Dec 24;4:480. doi: 10.3389/fimmu.2013.00480. eCollection 2013.


Diabetes-induced superoxide anion and breakdown of the blood-retinal barrier: role of the VEGF/uPAR pathway.

El-Remessy AB, Franklin T, Ghaley N, Yang J, Brands MW, Caldwell RB, Behzadian MA.

PLoS One. 2013 Aug 7;8(8):e71868. doi: 10.1371/journal.pone.0071868. eCollection 2013. Erratum in: PLoS One. 2017 Oct 16;12 (10 ):e0186749.


Macrophage involvement in mitral valve pathology in mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome).

Brands M, Roelants J, de Krijger R, Bogers A, Reuser A, van der Ploeg A, Helbing W.

Am J Med Genet A. 2013 Oct;161A(10):2550-3. doi: 10.1002/ajmg.a.36105. Epub 2013 Aug 15.


Characterization of novel MPS1 inhibitors with preclinical anticancer activity.

Jemaà M, Galluzzi L, Kepp O, Senovilla L, Brands M, Boemer U, Koppitz M, Lienau P, Prechtl S, Schulze V, Siemeister G, Wengner AM, Mumberg D, Ziegelbauer K, Abrieu A, Castedo M, Vitale I, Kroemer G.

Cell Death Differ. 2013 Nov;20(11):1532-45. doi: 10.1038/cdd.2013.105. Epub 2013 Aug 9.


Chronic blood pressure control.

Brands MW.

Compr Physiol. 2012 Oct;2(4):2481-94. doi: 10.1002/cphy.c100056. Review.


Early life stress sensitizes the renal and systemic sympathetic system in rats.

Loria AS, Brands MW, Pollock DM, Pollock JS.

Am J Physiol Renal Physiol. 2013 Aug 1;305(3):F390-5. doi: 10.1152/ajprenal.00008.2013. Epub 2013 May 15.


Renal collecting duct NOS1 maintains fluid-electrolyte homeostasis and blood pressure.

Hyndman KA, Boesen EI, Elmarakby AA, Brands MW, Huang P, Kohan DE, Pollock DM, Pollock JS.

Hypertension. 2013 Jul;62(1):91-8. doi: 10.1161/HYPERTENSIONAHA.113.01291. Epub 2013 Apr 22.


Mucopolysaccharidosis type VI phenotypes-genotypes and antibody response to galsulfase.

Brands MM, Hoogeveen-Westerveld M, Kroos MA, Nobel W, Ruijter GJ, Özkan L, Plug I, Grinberg D, Vilageliu L, Halley DJ, van der Ploeg AT, Reuser AJ.

Orphanet J Rare Dis. 2013 Apr 4;8:51. doi: 10.1186/1750-1172-8-51.


Up to five years experience with 11 mucopolysaccharidosis type VI patients.

Brands MM, Oussoren E, Ruijter GJ, Vollebregt AA, van den Hout HM, Joosten KF, Hop WC, Plug I, van der Ploeg AT.

Mol Genet Metab. 2013 May;109(1):70-6. doi: 10.1016/j.ymgme.2013.02.013. Epub 2013 Mar 4.


No difference in glycosphingolipid metabolism and mitochondrial function in glucocorticoid-induced insulin resistance in healthy men.

Brands M, van Raalte DH, João Ferraz M, Sauerwein HP, Verhoeven AJ, Aerts JM, Diamant M, Serlie MJ.

J Clin Endocrinol Metab. 2013 Mar;98(3):1219-25. doi: 10.1210/jc.2012-3266. Epub 2013 Feb 5.


Omega-3 long-chain fatty acids strongly induce angiopoietin-like 4 in humans.

Brands M, Sauerwein HP, Ackermans MT, Kersten S, Serlie MJ.

J Lipid Res. 2013 Mar;54(3):615-21. doi: 10.1194/jlr.M030049. Epub 2013 Jan 14.


Sodium-retaining effect of insulin in diabetes.

Brands MW, Manhiani MM.

Am J Physiol Regul Integr Comp Physiol. 2012 Dec;303(11):R1101-9. doi: 10.1152/ajpregu.00390.2012. Epub 2012 Oct 3. Review.


Angiopoietin-like protein 4 is differentially regulated by glucocorticoids and insulin in vitro and in vivo in healthy humans.

van Raalte DH, Brands M, Serlie MJ, Mudde K, Stienstra R, Sauerwein HP, Kersten S, Diamant M.

Exp Clin Endocrinol Diabetes. 2012 Nov;120(10):598-603. doi: 10.1055/s-0032-1321864. Epub 2012 Sep 12.


Role of mitochondrial function in insulin resistance.

Brands M, Verhoeven AJ, Serlie MJ.

Adv Exp Med Biol. 2012;942:215-34. doi: 10.1007/978-94-007-2869-1_9.


Effects of a hypercaloric diet on β-cell responsivity in lean healthy men.

Brands M, Swat M, Lammers NM, Sauerwein HP, Endert E, Ackermans MT, Verhoeven AJ, Serlie MJ.

Clin Endocrinol (Oxf). 2013 Feb;78(2):217-25. doi: 10.1111/j.1365-2265.2012.04364.x.


Mucopolysaccharidosis: cardiologic features and effects of enzyme-replacement therapy in 24 children with MPS I, II and VI.

Brands MM, Frohn-Mulder IM, Hagemans ML, Hop WC, Oussoren E, Helbing WA, van der Ploeg AT.

J Inherit Metab Dis. 2013 Mar;36(2):227-34. doi: 10.1007/s10545-011-9444-z. Epub 2012 Jan 26.

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