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Items: 1 to 50 of 71

1.

RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation.

Bustos F, Segarra-Fas A, Chaugule VK, Brandenburg L, Branigan E, Toth R, Macartney T, Knebel A, Hay RT, Walden H, Findlay GM.

Cell Rep. 2018 May 8;23(6):1599-1611. doi: 10.1016/j.celrep.2018.04.022.

2.

Toll-Like Receptor 2-Mediated Glial Cell Activation in a Mouse Model of Cuprizone-Induced Demyelination.

Esser S, Göpfrich L, Bihler K, Kress E, Nyamoya S, Tauber SC, Clarner T, Stope MB, Pufe T, Kipp M, Brandenburg LO.

Mol Neurobiol. 2017 Dec 29. doi: 10.1007/s12035-017-0838-2. [Epub ahead of print]

PMID:
29288338
3.

CRAMP deficiency leads to a pro-inflammatory phenotype and impaired phagocytosis after exposure to bacterial meningitis pathogens.

Kress E, Merres J, Albrecht LJ, Hammerschmidt S, Pufe T, Tauber SC, Brandenburg LO.

Cell Commun Signal. 2017 Sep 16;15(1):32. doi: 10.1186/s12964-017-0190-1.

4.

Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain lesion formation and progression.

Rüther BJ, Scheld M, Dreymueller D, Clarner T, Kress E, Brandenburg LO, Swartenbroekx T, Hoornaert C, Ponsaerts P, Fallier-Becker P, Beyer C, Rohr SO, Schmitz C, Chrzanowski U, Hochstrasser T, Nyamoya S, Kipp M.

Glia. 2017 Dec;65(12):1900-1913. doi: 10.1002/glia.23202. Epub 2017 Aug 24.

PMID:
28836302
5.

Different Cytokine and Chemokine Expression Patterns in Malignant Compared to Those in Nonmalignant Renal Cells.

Gelbrich N, Ahrend H, Kaul A, Brandenburg LO, Zimmermann U, Mustea A, Burchardt M, Gümbel D, Stope MB.

Anal Cell Pathol (Amst). 2017;2017:7190546. doi: 10.1155/2017/7190546. Epub 2017 Jul 9.

6.

MicroRNA-1 and MicroRNA-21 Individually Regulate Cellular Growth of Non-malignant and Malignant Renal Cells.

Ahrend H, Kaul A, Ziegler S, Brandenburg LO, Zimmermann U, Mustea A, Burchardt M, Ziegler P, Stope MB.

In Vivo. 2017 Jul-Aug;31(4):625-630.

7.

Formyl Peptide Receptor 1-Mediated Glial Cell Activation in a Mouse Model of Cuprizone-Induced Demyelination.

Bihler K, Kress E, Esser S, Nyamoya S, Tauber SC, Clarner T, Stope MB, Pufe T, Brandenburg LO.

J Mol Neurosci. 2017 Jun;62(2):232-243. doi: 10.1007/s12031-017-0924-y. Epub 2017 May 2.

PMID:
28466255
8.

Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease.

Fragoulis A, Siegl S, Fendt M, Jansen S, Soppa U, Brandenburg LO, Pufe T, Weis J, Wruck CJ.

Redox Biol. 2017 Aug;12:843-853. doi: 10.1016/j.redox.2017.04.024. Epub 2017 Apr 19.

9.

Psoriasin has divergent effects on the innate immune responses of murine glial cells.

Jansen S, Kress E, Fragoulis A, Wruck CJ, Wolf R, Grötzinger J, Michalek M, Pufe T, Tauber SC, Brandenburg LO.

J Neurochem. 2017 Apr;141(1):86-99. doi: 10.1111/jnc.13959. Epub 2017 Feb 27.

10.

Lack of Toll-like receptor 2 results in higher mortality of bacterial meningitis by impaired host resistance.

Böhland M, Kress E, Stope MB, Pufe T, Tauber SC, Brandenburg LO.

J Neuroimmunol. 2016 Oct 15;299:90-97. doi: 10.1016/j.jneuroim.2016.09.003. Epub 2016 Sep 6.

PMID:
27725130
11.

Reducing Behavior Problems Among Students with Autism Spectrum Disorder: Coaching Teachers in a Mixed-Reality Setting.

Pas ET, Johnson SR, Larson KE, Brandenburg L, Church R, Bradshaw CP.

J Autism Dev Disord. 2016 Dec;46(12):3640-3652.

PMID:
27590663
12.

In Vitro Cultivation of Primary Prostate Cancer Cells Alters the Molecular Biomarker Pattern.

Caspar A, Mostertz J, Leymann M, Ziegler P, Evert K, Evert M, Zimmermann U, Brandenburg LO, Burchardt M, Stope MB.

In Vivo. 2016 09-10;30(5):573-9.

PMID:
27566074
13.

Do Innate Immune Gene Variations Contribute to Susceptibility and Severity of Pneumococcal Meningitis?

Brandenburg LO, Tauber SC.

EBioMedicine. 2016 Aug;10:9-10. doi: 10.1016/j.ebiom.2016.07.029. Epub 2016 Jul 26. No abstract available.

14.

MicroRNA-1 properties in cancer regulatory networks and tumor biology.

Weiss M, Brandenburg LO, Burchardt M, Stope MB.

Crit Rev Oncol Hematol. 2016 Aug;104:71-7. doi: 10.1016/j.critrevonc.2016.05.014. Epub 2016 May 26. Review.

PMID:
27286699
15.

Lack of Proinflammatory Cytokine Interleukin-6 or Tumor Necrosis Factor Receptor-1 Results in a Failure of the Innate Immune Response after Bacterial Meningitis.

Albrecht LJ, Tauber SC, Merres J, Kress E, Stope MB, Jansen S, Pufe T, Brandenburg LO.

Mediators Inflamm. 2016;2016:7678542. doi: 10.1155/2016/7678542. Epub 2016 Jan 28.

16.

Cytochrome P450 17A1 Inhibitor Abiraterone Acetate Counteracts the Heat Shock Protein 27's Cell Survival Properties in Prostate Cancer Cells.

Weiss M, Ahrend H, Grossebrummel H, Ziegler P, Brandenburg LO, Walther R, Zimmermann U, Burchardt M, Stope MB.

Urol Int. 2016;97(1):112-7. doi: 10.1159/000445251. Epub 2016 Mar 24.

PMID:
27007943
17.

Exosomal particles secreted by prostate cancer cells are potent mRNA and protein vehicles for the interference of tumor and tumor environment.

Rauschenberger L, Staar D, Thom K, Scharf C, Venz S, Homuth G, Schlüter R, Brandenburg LO, Ziegler P, Zimmermann U, Weitschies W, Völker U, Lendeckel U, Walther R, Burchardt M, Stope MB.

Prostate. 2016 Mar;76(4):409-24. doi: 10.1002/pros.23132. Epub 2015 Dec 8.

PMID:
26643154
18.

Inhibition of Cell Growth of the Prostate Cancer Cell Model LNCaP by Cold Atmospheric Plasma.

Weiss M, Gümbel D, Gelbrich N, Brandenburg LO, Mandelkow R, Zimmermann U, Ziegler P, Burchardt M, Stope MB.

In Vivo. 2015 Sep-Oct;29(5):611-6.

PMID:
26359422
19.

Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy.

Schumacher A, Denecke B, Braunschweig T, Stahlschmidt J, Ziegler S, Brandenburg LO, Stope MB, Martincuks A, Vogt M, Görtz D, Camporeale A, Poli V, Müller-Newen G, Brümmendorf TH, Ziegler P.

J Hematol Oncol. 2015 Jun 9;8:64. doi: 10.1186/s13045-015-0152-2.

20.

The Anti-Microbial Peptide LL-37/CRAMP Is Elevated in Patients with Liver Diseases and Acts as a Protective Factor during Mouse Liver Injury.

Wertenbruch S, Drescher H, Grossarth V, Kroy D, Giebeler A, Erschfeld S, Heinrichs D, Soehnlein O, Trautwein C, Brandenburg LO, Streetz K.

Digestion. 2015;91(4):307-17. doi: 10.1159/000368304. Epub 2015 May 13.

PMID:
25998843
21.

Intrathecal application of the antimicrobial peptide CRAMP reduced mortality and neuroinflammation in an experimental model of pneumococcal meningitis.

Dörr A, Kress E, Podschun R, Pufe T, Tauber SC, Brandenburg LO.

J Infect. 2015 Aug;71(2):188-99. doi: 10.1016/j.jinf.2015.04.006. Epub 2015 Apr 17.

PMID:
25896094
22.

Adjuvant granulocyte colony-stimulating factor therapy results in improved spatial learning and stimulates hippocampal neurogenesis in a mouse model of pneumococcal meningitis.

Schmidt AK, Reich A, Falkenburger B, Schulz JB, Brandenburg LO, Ribes S, Tauber SC.

J Neuropathol Exp Neurol. 2015 Jan;74(1):85-94. doi: 10.1097/NEN.0000000000000152.

PMID:
25470346
23.

Mechanical forces induce changes in VEGF and VEGFR-1/sFlt-1 expression in human chondrocytes.

Beckmann R, Houben A, Tohidnezhad M, Kweider N, Fragoulis A, Wruck CJ, Brandenburg LO, Hermanns-Sachweh B, Goldring MB, Pufe T, Jahr H.

Int J Mol Sci. 2014 Sep 1;15(9):15456-74. doi: 10.3390/ijms150915456.

24.

Role of phospholipase d in g-protein coupled receptor function.

Brandenburg LO, Pufe T, Koch T.

Membranes (Basel). 2014 Jul 3;4(3):302-18. doi: 10.3390/membranes4030302.

25.

Deficiency of formyl peptide receptor 1 and 2 is associated with increased inflammation and enhanced liver injury after LPS-stimulation.

Giebeler A, Streetz KL, Soehnlein O, Neumann U, Wang JM, Brandenburg LO.

PLoS One. 2014 Jun 23;9(6):e100522. doi: 10.1371/journal.pone.0100522. eCollection 2014.

26.

Lack of formyl peptide receptor 1 and 2 leads to more severe inflammation and higher mortality in mice with of pneumococcal meningitis.

Oldekamp S, Pscheidl S, Kress E, Soehnlein O, Jansen S, Pufe T, Wang JM, Tauber SC, Brandenburg LO.

Immunology. 2014 Nov;143(3):447-61. doi: 10.1111/imm.12324.

27.

Role of platelet-released growth factors in detoxification of reactive oxygen species in osteoblasts.

Tohidnezhad M, Wruck CJ, Slowik A, Kweider N, Beckmann R, Bayer A, Houben A, Brandenburg LO, Varoga D, Sönmez TT, Stoffel M, Jahr H, Lippross S, Pufe T.

Bone. 2014 Aug;65:9-17. doi: 10.1016/j.bone.2014.04.029. Epub 2014 May 4.

PMID:
24798492
28.

Role of the cathelicidin-related antimicrobial peptide in inflammation and mortality in a mouse model of bacterial meningitis.

Merres J, Höss J, Albrecht LJ, Kress E, Soehnlein O, Jansen S, Pufe T, Tauber SC, Brandenburg LO.

J Innate Immun. 2014;6(2):205-18. doi: 10.1159/000353645. Epub 2013 Aug 22. Erratum in: J Innate Immun. 2017;9(1):108.

PMID:
23969854
29.

Expression and function of psoriasin (S100A7) and koebnerisin (S100A15) in the brain.

Jansen S, Podschun R, Leib SL, Grötzinger J, Oestern S, Michalek M, Pufe T, Brandenburg LO.

Infect Immun. 2013 May;81(5):1788-97. doi: 10.1128/IAI.01265-12. Epub 2013 Mar 11.

30.

Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE)--and amyloid beta 1-42-induced signal transduction in glial cells.

Slowik A, Merres J, Elfgen A, Jansen S, Mohr F, Wruck CJ, Pufe T, Brandenburg LO.

Mol Neurodegener. 2012 Nov 20;7:55. doi: 10.1186/1750-1326-7-55.

31.

CpG oligodeoxynucleotides induce the expression of the antimicrobial peptide cathelicidin in glial cells.

Brandenburg LO, Jansen S, Albrecht LJ, Merres J, Gerber J, Pufe T, Tauber SC.

J Neuroimmunol. 2013 Feb 15;255(1-2):18-31. doi: 10.1016/j.jneuroim.2012.10.012. Epub 2012 Nov 8.

PMID:
23141747
32.

Lack of hepatic c-Met and gp130 expression is associated with an impaired antibacterial response and higher lethality after bile duct ligation.

Giebeler A, Brandenburg LO, Kaldenbach M, Erschfeld S, Wasmuth H, Wruck C, Trautwein C, Streetz KL.

Lab Invest. 2012 Dec;92(12):1726-37. doi: 10.1038/labinvest.2012.122. Epub 2012 Sep 17.

33.

[Treatment of a partial avascular necrosis of a metacarpal head (Morbus Mauclaire Dieterich's Disease) utilizing the ostechondral autograft transfer system (OATS) technique].

Braun BJ, Brandenburg LO, Braun C.

Handchir Mikrochir Plast Chir. 2012 Jan;44(1):35-9. doi: 10.1055/s-0031-1291316. Epub 2012 Mar 1. German.

PMID:
22382907
34.

Impact of Nrf2 on esophagus epithelium cornification.

Wruck CJ, Wruck A, Brandenburg LO, Kadyrov M, Tohidnezhad M, Pufe T.

Int J Dermatol. 2011 Nov;50(11):1362-5. doi: 10.1111/j.1365-4632.2011.04989.x.

PMID:
22004488
35.

Nrf2 expression by neurons, astroglia, and microglia in the cerebral cortical penumbra of ischemic rats.

Dang J, Brandenburg LO, Rosen C, Fragoulis A, Kipp M, Pufe T, Beyer C, Wruck CJ.

J Mol Neurosci. 2012 Mar;46(3):578-84. doi: 10.1007/s12031-011-9645-9. Epub 2011 Sep 7.

PMID:
21932039
36.

Platelets display potent antimicrobial activity and release human beta-defensin 2.

Tohidnezhad M, Varoga D, Wruck CJ, Podschun R, Sachweh BH, Bornemann J, Bovi M, Sönmez TT, Slowik A, Houben A, Seekamp A, Brandenburg LO, Pufe T, Lippross S.

Platelets. 2012;23(3):217-23. doi: 10.3109/09537104.2011.610908. Epub 2011 Sep 13.

PMID:
21913811
37.

Platelet-released growth factors can accelerate tenocyte proliferation and activate the anti-oxidant response element.

Tohidnezhad M, Varoga D, Wruck CJ, Brandenburg LO, Seekamp A, Shakibaei M, Sönmez TT, Pufe T, Lippross S.

Histochem Cell Biol. 2011 May;135(5):453-60. doi: 10.1007/s00418-011-0808-0. Epub 2011 Apr 8.

PMID:
21476078
38.

Complex patterns of ADAM12 mRNA and protein splice variants in the human placenta.

Kokozidou M, Drewlo S, Bartz C, Raven G, Brandenburg LO, Wruck CJ, Pufe T.

Ann Anat. 2011 Mar;193(2):142-8. doi: 10.1016/j.aanat.2010.12.002. Epub 2011 Jan 26.

PMID:
21330122
39.

Thrombocytes are effectors of the innate immune system releasing human beta defensin-3.

Tohidnezhad M, Varoga D, Podschun R, Wruck CJ, Seekamp A, Brandenburg LO, Pufe T, Lippross S.

Injury. 2011 Jul;42(7):682-6. doi: 10.1016/j.injury.2010.12.010. Epub 2011 Feb 10.

PMID:
21310405
40.

The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis.

Braun BJ, Slowik A, Leib SL, Lucius R, Varoga D, Wruck CJ, Jansen S, Podschun R, Pufe T, Brandenburg LO.

J Neuroinflammation. 2011 Feb 7;8(1):11. doi: 10.1186/1742-2094-8-11.

41.

Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice.

Wruck CJ, Fragoulis A, Gurzynski A, Brandenburg LO, Kan YW, Chan K, Hassenpflug J, Freitag-Wolf S, Varoga D, Lippross S, Pufe T.

Ann Rheum Dis. 2011 May;70(5):844-50. doi: 10.1136/ard.2010.132720. Epub 2010 Dec 20.

PMID:
21173018
42.

Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter.

Wruck CJ, Streetz K, Pavic G, Götz ME, Tohidnezhad M, Brandenburg LO, Varoga D, Eickelberg O, Herdegen T, Trautwein C, Cha K, Kan YW, Pufe T.

J Biol Chem. 2011 Feb 11;286(6):4493-9. doi: 10.1074/jbc.M110.162008. Epub 2010 Dec 2.

43.

17β-estradiol reduces expression of MMP-1, -3, and -13 in human primary articular chondrocytes from female patients cultured in a three dimensional alginate system.

Claassen H, Steffen R, Hassenpflug J, Varoga D, Wruck CJ, Brandenburg LO, Pufe T.

Cell Tissue Res. 2010 Nov;342(2):283-93. doi: 10.1007/s00441-010-1062-9. Epub 2010 Oct 13.

PMID:
20941509
44.

Effects of controlled released BMP-7 on markers of inflammation and degradation during the cultivation of human osteoarthritic chondrocytes.

Gavenis K, Pufe T, Brandenburg LO, Schiffl K, Schmidt-Rohlfing B.

J Biomater Appl. 2011 Nov;26(4):419-33. doi: 10.1177/0885328210374671. Epub 2010 Jul 12.

PMID:
20624843
45.

Antimicrobial peptide rCRAMP induced glial cell activation through P2Y receptor signalling pathways.

Brandenburg LO, Jansen S, Wruck CJ, Lucius R, Pufe T.

Mol Immunol. 2010 Jun;47(10):1905-13. doi: 10.1016/j.molimm.2010.03.012. Epub 2010 Apr 13.

PMID:
20392497
46.

Role of phospholipase D2/phosphatidic acid signal transduction in micro- and delta-opioid receptor endocytosis.

Yang L, Seifert A, Wu D, Wang X, Rankovic V, Schröder H, Brandenburg LO, Höllt V, Koch T.

Mol Pharmacol. 2010 Jul;78(1):105-13. doi: 10.1124/mol.109.063107. Epub 2010 Mar 30.

47.

ADAM12 is expressed by astrocytes during experimental demyelination.

Baertling F, Kokozidou M, Pufe T, Clarner T, Windoffer R, Wruck CJ, Brandenburg LO, Beyer C, Kipp M.

Brain Res. 2010 Apr 22;1326:1-14. doi: 10.1016/j.brainres.2010.02.049. Epub 2010 Feb 20.

PMID:
20176000
48.

Functional and physical interactions between formyl-peptide-receptors and scavenger receptor MARCO and their involvement in amyloid beta 1-42-induced signal transduction in glial cells.

Brandenburg LO, Konrad M, Wruck CJ, Koch T, Lucius R, Pufe T.

J Neurochem. 2010 May;113(3):749-60. doi: 10.1111/j.1471-4159.2010.06637.x. Epub 2010 Feb 5.

49.

Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils.

Wilms H, Rosenstiel P, Romero-Ramos M, Arlt A, Schäfer H, Seegert D, Kahle PJ, Odoy S, Claasen JH, Holzknecht C, Brandenburg LO, Deuschl G, Schreiber S, Kirik D, Lucius R.

Int J Immunopathol Pharmacol. 2009 Oct-Dec;22(4):897-909.

PMID:
20074453
50.

Sulforaphane suppresses LPS-induced inflammation in primary rat microglia.

Brandenburg LO, Kipp M, Lucius R, Pufe T, Wruck CJ.

Inflamm Res. 2010 Jun;59(6):443-50. doi: 10.1007/s00011-009-0116-5. Epub 2009 Nov 19.

PMID:
19924513

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