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Items: 40


Mercaptopyruvate acts as endogenous vasodilator independently of 3-mercaptopyruvate sulfurtransferase activity.

Mitidieri E, Tramontano T, Gurgone D, Citi V, Calderone V, Brancaleone V, Katsouda A, Nagahara N, Papapetropoulos A, Cirino G, d'Emmanuele di Villa Bianca R, Sorrentino R.

Nitric Oxide. 2018 May 1;75:53-59. doi: 10.1016/j.niox.2018.02.003. Epub 2018 Feb 13.


Disodium cromoglycate inhibits asthma-like features induced by sphingosine-1-phosphate.

Roviezzo F, Sorrentino R, Iacono VM, Brancaleone V, Terlizzi M, Riemma MA, Bertolino A, Rossi A, Matteis M, Spaziano G, Pinto A, D'Agostino B, Cirino G.

Pharmacol Res. 2016 Nov;113(Pt A):626-635. doi: 10.1016/j.phrs.2016.09.014. Epub 2016 Oct 3.


The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress.

Testai L, Marino A, Piano I, Brancaleone V, Tomita K, Di Cesare Mannelli L, Martelli A, Citi V, Breschi MC, Levi R, Gargini C, Bucci M, Cirino G, Ghelardini C, Calderone V.

Pharmacol Res. 2016 Nov;113(Pt A):290-299. doi: 10.1016/j.phrs.2016.09.006. Epub 2016 Sep 9.


Proteinase activated receptor-2 counterbalances the vascular effects of endothelin-1 in fibrotic tight-skin mice.

Roviezzo F, Brancaleone V, Mattera Iacono V, Bertolino A, De Cunto G, Vellecco V, Lungarella G, Lucattelli M, Cirino G.

Br J Pharmacol. 2017 Nov;174(22):4032-4042. doi: 10.1111/bph.13618. Epub 2016 Oct 5.


Vascular effects of linagliptin in non-obese diabetic mice are glucose-independent and involve positive modulation of the endothelial nitric oxide synthase (eNOS)/caveolin-1 (CAV-1) pathway.

Vellecco V, Mitidieri E, Gargiulo A, Brancaleone V, Matassa D, Klein T, Esposito F, Cirino G, Bucci M.

Diabetes Obes Metab. 2016 Dec;18(12):1236-1243. doi: 10.1111/dom.12750. Epub 2016 Aug 30.


l-Cys/CSE/H2S pathway modulates mouse uterus motility and sildenafil effect.

Mitidieri E, Tramontano T, Donnarumma E, Brancaleone V, Cirino G, D Emmanuele di Villa Bianca R, Sorrentino R.

Pharmacol Res. 2016 Sep;111:283-289. doi: 10.1016/j.phrs.2016.06.017. Epub 2016 Jun 17.


D-Penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine-γ-lyase.

Brancaleone V, Esposito I, Gargiulo A, Vellecco V, Asimakopoulou A, Citi V, Calderone V, Gobbetti T, Perretti M, Papapetropoulos A, Bucci M, Cirino G.

Br J Pharmacol. 2016 May;173(9):1556-65. doi: 10.1111/bph.13459. Epub 2016 Mar 23.


Erratum to "Adaptive Immunity and Inflammation".

Brancaleone V, Iqbal AJ, Paschalidis N, Maione F.

Int J Inflam. 2015;2015:514686. doi: 10.1155/2015/514686. Epub 2015 May 11.


Hydrogen sulfide is involved in dexamethasone-induced hypertension in rat.

d'Emmanuele di Villa Bianca R, Mitidieri E, Donnarumma E, Tramontano T, Brancaleone V, Cirino G, Bucci M, Sorrentino R.

Nitric Oxide. 2015 Apr 30;46:80-6. doi: 10.1016/j.niox.2014.11.013. Epub 2014 Nov 25.


Annexin A1 mediates hydrogen sulfide properties in the control of inflammation.

Brancaleone V, Mitidieri E, Flower RJ, Cirino G, Perretti M.

J Pharmacol Exp Ther. 2014 Oct;351(1):96-104. doi: 10.1124/jpet.114.217034. Epub 2014 Jul 30.


Crucial role of androgen receptor in vascular H2S biosynthesis induced by testosterone.

Brancaleone V, Vellecco V, Matassa DS, d'Emmanuele di Villa Bianca R, Sorrentino R, Ianaro A, Bucci M, Esposito F, Cirino G.

Br J Pharmacol. 2015 Mar;172(6):1505-15. doi: 10.1111/bph.12740. Epub 2014 Jul 2.


Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition.

Bucci M, Vellecco V, Cantalupo A, Brancaleone V, Zhou Z, Evangelista S, Calderone V, Papapetropoulos A, Cirino G.

Cardiovasc Res. 2014 Apr 1;102(1):138-47. doi: 10.1093/cvr/cvu026. Epub 2014 Feb 5.


Involvement of proteinase activated receptor-2 in the vascular response to sphingosine 1-phosphate.

Roviezzo F, De Angelis A, De Gruttola L, Bertolino A, Sullo N, Brancaleone V, Bucci M, De Palma R, Urbanek K, D'Agostino B, Ianaro A, Sorrentino R, Cirino G.

Clin Sci (Lond). 2014 Apr;126(8):545-56. doi: 10.1042/CS20130272.


Chemerin15 inhibits neutrophil-mediated vascular inflammation and myocardial ischemia-reperfusion injury through ChemR23.

Cash JL, Bena S, Headland SE, McArthur S, Brancaleone V, Perretti M.

EMBO Rep. 2013 Nov;14(11):999-1007. doi: 10.1038/embor.2013.138. Epub 2013 Sep 3.


Biphasic modulation of NOS expression, protein and nitrite products by hydroxocobalamin underlies its protective effect in endotoxemic shock: downstream regulation of COX-2, IL-1β, TNF-α, IL-6, and HMGB1 expression.

Sampaio AL, Dalli J, Brancaleone V, D'Acquisto F, Perretti M, Wheatley C.

Mediators Inflamm. 2013;2013:741804. doi: 10.1155/2013/741804. Epub 2013 May 28.


A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation.

Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S, Perretti M.

Blood. 2013 Jul 25;122(4):608-17. doi: 10.1182/blood-2013-04-496661. Epub 2013 Jun 3.


Annexin-A1 protein and its relationship to cortisol in human saliva.

Fowkes RC, Moradi-Bidhendi N, Brancaleone V, Zariwala MG, Brady D, Jessop DS, Perretti M, Renshaw D.

Psychoneuroendocrinology. 2013 May;38(5):722-7. doi: 10.1016/j.psyneuen.2012.08.003. Epub 2012 Sep 25. Erratum in: Psychoneuroendocrinology. 2014 Sep;47:246. Branceleone, Vincenzo [corrected to Brancaleone, Vincenzo].


Cross-talk between toll-like receptor 4 (TLR4) and proteinase-activated receptor 2 (PAR(2) ) is involved in vascular function.

Bucci M, Vellecco V, Harrington L, Brancaleone V, Roviezzo F, Mattace Raso G, Ianaro A, Lungarella G, De Palma R, Meli R, Cirino G.

Br J Pharmacol. 2013 Jan;168(2):411-20. doi: 10.1111/j.1476-5381.2012.02205.x.


Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signaling.

Bena S, Brancaleone V, Wang JM, Perretti M, Flower RJ.

J Biol Chem. 2012 Jul 13;287(29):24690-7. doi: 10.1074/jbc.M112.377101. Epub 2012 May 18.


Distinct localization of T cell Agrin during antigen presentation--evidence for the expression of Agrin receptor(s) in antigen-presenting cells.

Kabouridis PS, Pimentel TA, Brancaleone V, D'Acquisto F, Oliani SM, Perretti M, Jury EC.

FEBS J. 2012 Jul;279(13):2368-80. doi: 10.1111/j.1742-4658.2012.08615.x. Epub 2012 May 21.


Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes.

Nadkarni S, Cooper D, Brancaleone V, Bena S, Perretti M.

Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2749-59. doi: 10.1161/ATVBAHA.111.235176.


Sphingosine-1-phosphate modulates vascular permeability and cell recruitment in acute inflammation in vivo.

Roviezzo F, Brancaleone V, De Gruttola L, Vellecco V, Bucci M, D'Agostino B, Cooper D, Sorrentino R, Perretti M, Cirino G.

J Pharmacol Exp Ther. 2011 Jun;337(3):830-7. doi: 10.1124/jpet.111.179168. Epub 2011 Mar 18.


Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature.

Brancaleone V, Dalli J, Bena S, Flower RJ, Cirino G, Perretti M.

J Immunol. 2011 Apr 15;186(8):4905-14. doi: 10.4049/jimmunol.1003145. Epub 2011 Mar 11.


Downstream gene activation of the receptor ALX by the agonist annexin A1.

Renshaw D, Montero-Melendez T, Dalli J, Kamal A, Brancaleone V, D'Acquisto F, Cirino G, Perretti M.

PLoS One. 2010 Sep 17;5(9). pii: e12771. doi: 10.1371/journal.pone.0012771.


Hydrogen sulfide is an endogenous inhibitor of phosphodiesterase activity.

Bucci M, Papapetropoulos A, Vellecco V, Zhou Z, Pyriochou A, Roussos C, Roviezzo F, Brancaleone V, Cirino G.

Arterioscler Thromb Vasc Biol. 2010 Oct;30(10):1998-2004. doi: 10.1161/ATVBAHA.110.209783. Epub 2010 Jul 15.


Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation.

Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC, Perretti M, Flower RJ.

J Immunol. 2010 Mar 1;184(5):2611-2619. doi: 10.4049/jimmunol.0903526. Epub 2010 Jan 27. Erratum in: J Immunol. 2011 Feb 15;186(4):2684-5.


The bile acid sensor FXR regulates insulin transcription and secretion.

Renga B, Mencarelli A, Vavassori P, Brancaleone V, Fiorucci S.

Biochim Biophys Acta. 2010 Mar;1802(3):363-72. doi: 10.1016/j.bbadis.2010.01.002. Epub 2010 Jan 7.


Systemic administration of sphingosine-1-phosphate increases bronchial hyperresponsiveness in the mouse.

Roviezzo F, D'Agostino B, Brancaleone V, De Gruttola L, Bucci M, De Dominicis G, Orlotti D, D'Aiuto E, De Palma R, Rossi F, Sorrentino R, Cirino G.

Am J Respir Cell Mol Biol. 2010 May;42(5):572-7. doi: 10.1165/rcmb.2009-0108OC. Epub 2009 Jun 25.


Characterisation of cystathionine gamma-lyase/hydrogen sulphide pathway in ischaemia/reperfusion injury of the mouse kidney: an in vivo study.

Tripatara P, Patel NS, Brancaleone V, Renshaw D, Rocha J, Sepodes B, Mota-Filipe H, Perretti M, Thiemermann C.

Eur J Pharmacol. 2009 Mar 15;606(1-3):205-9. doi: 10.1016/j.ejphar.2009.01.041. Epub 2009 Feb 5.


Biosynthesis of H2S is impaired in non-obese diabetic (NOD) mice.

Brancaleone V, Roviezzo F, Vellecco V, De Gruttola L, Bucci M, Cirino G.

Br J Pharmacol. 2008 Nov;155(5):673-80. doi: 10.1038/bjp.2008.296. Epub 2008 Jul 21.


ACE-inhibition ameliorates vascular reactivity and delays diabetes outcome in NOD mice.

Bucci M, Roviezzo F, Brancaleone V, Di Lorenzo A, Evangelista S, Gori M, Cirino G.

Vascul Pharmacol. 2008 Aug-Sep;49(2-3):84-90. doi: 10.1016/j.vph.2008.06.002. Epub 2008 Jun 13.


Hydrogen sulphide is involved in testosterone vascular effect.

Bucci M, Mirone V, Di Lorenzo A, Vellecco V, Roviezzo F, Brancaleone V, Ciro I, Cirino G.

Eur Urol. 2009 Aug;56(2):378-83. doi: 10.1016/j.eururo.2008.05.014. Epub 2008 May 22.


Protective role of PI3-kinase-Akt-eNOS signalling pathway in intestinal injury associated with splanchnic artery occlusion shock.

Roviezzo F, Cuzzocrea S, Di Lorenzo A, Brancaleone V, Mazzon E, Di Paola R, Bucci M, Cirino G.

Br J Pharmacol. 2007 Jun;151(3):377-83. Epub 2007 Apr 23.


Sphingosine-1-phosphate/sphingosine kinase pathway is involved in mouse airway hyperresponsiveness.

Roviezzo F, Di Lorenzo A, Bucci M, Brancaleone V, Vellecco V, De Nardo M, Orlotti D, De Palma R, Rossi F, D'Agostino B, Cirino G.

Am J Respir Cell Mol Biol. 2007 Jun;36(6):757-62. Epub 2007 Feb 22.


Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation.

Zanardo RC, Brancaleone V, Distrutti E, Fiorucci S, Cirino G, Wallace JL.

FASEB J. 2006 Oct;20(12):2118-20. Epub 2006 Aug 15.


Essential requirement for sphingosine kinase activity in eNOS-dependent NO release and vasorelaxation.

Roviezzo F, Bucci M, Delisle C, Brancaleone V, Di Lorenzo A, Mayo IP, Fiorucci S, Fontana A, Gratton JP, Cirino G.

FASEB J. 2006 Feb;20(2):340-2. Epub 2005 Dec 1.


Proteinase-activated receptor-2 mediates arterial vasodilation in diabetes.

Roviezzo F, Bucci M, Brancaleone V, Di Lorenzo A, Geppetti P, Farneti S, Parente L, Lungarella G, Fiorucci S, Cirino G.

Arterioscler Thromb Vasc Biol. 2005 Nov;25(11):2349-54. Epub 2005 Sep 1.


Angiopoietin-2 causes inflammation in vivo by promoting vascular leakage.

Roviezzo F, Tsigkos S, Kotanidou A, Bucci M, Brancaleone V, Cirino G, Papapetropoulos A.

J Pharmacol Exp Ther. 2005 Aug;314(2):738-44. Epub 2005 May 3.


Diabetic mouse angiopathy is linked to progressive sympathetic receptor deletion coupled to an enhanced caveolin-1 expression.

Bucci M, Roviezzo F, Brancaleone V, Lin MI, Di Lorenzo A, Cicala C, Pinto A, Sessa WC, Farneti S, Fiorucci S, Cirino G.

Arterioscler Thromb Vasc Biol. 2004 Apr;24(4):721-6. Epub 2004 Feb 12.


NCX-1000, a nitric oxide-releasing derivative of ursodeoxycholic acid, ameliorates portal hypertension and lowers norepinephrine-induced intrahepatic resistance in the isolated and perfused rat liver.

Fiorucci S, Antonelli E, Brancaleone V, Sanpaolo L, Orlandi S, Distrutti E, Acuto G, Clerici C, Baldoni M, Del Soldato P, Morelli A.

J Hepatol. 2003 Dec;39(6):932-9.


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