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Items: 1 to 50 of 165

1.

Adverse Effects of Immune Checkpoint Inhibitors (Programmed Death-1 Inhibitors and Cytotoxic T-Lymphocyte-Associated Protein-4 Inhibitors): Results of a Retrospective Study.

Bajwa R, Cheema A, Khan T, Amirpour A, Paul A, Chaughtai S, Patel S, Patel T, Bramson J, Gupta V, Levitt M, Asif A, Hossain MA.

J Clin Med Res. 2019 Apr;11(4):225-236. doi: 10.14740/jocmr3750. Epub 2019 Mar 18. Review.

2.

Trends in Hospice Quality Oversight and Key Challenges to Making it More Effective, 2006-2015.

Stevenson D, Sinclair N, Krone E, Bramson J.

J Palliat Med. 2019 Jun;22(6):670-676. doi: 10.1089/jpm.2018.0445. Epub 2019 Jan 9.

PMID:
30625006
3.

Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials.

Pol JG, Acuna SA, Yadollahi B, Tang N, Stephenson KB, Atherton MJ, Hanwell D, El-Warrak A, Goldstein A, Moloo B, Turner PV, Lopez R, LaFrance S, Evelegh C, Denisova G, Parsons R, Millar J, Stoll G, Martin CG, Pomoransky J, Breitbach CJ, Bramson JL, Bell JC, Wan Y, Stojdl DF, Lichty BD, McCart JA.

Oncoimmunology. 2018 Sep 19;8(1):e1512329. doi: 10.1080/2162402X.2018.1512329. eCollection 2019.

4.

Type I IFN blockade uncouples immunotherapy-induced antitumor immunity and autoimmune toxicity.

Walsh SR, Bastin D, Chen L, Nguyen A, Storbeck CJ, Lefebvre C, Stojdl D, Bramson JL, Bell JC, Wan Y.

J Clin Invest. 2019 Feb 1;129(2):518-530. doi: 10.1172/JCI121004. Epub 2018 Dec 18.

5.

The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity.

Helsen CW, Hammill JA, Lau VWC, Mwawasi KA, Afsahi A, Bezverbnaya K, Newhook L, Hayes DL, Aarts C, Bojovic B, Denisova GF, Kwiecien JM, Brain I, Derocher H, Milne K, Nelson BH, Bramson JL.

Nat Commun. 2018 Aug 3;9(1):3049. doi: 10.1038/s41467-018-05395-y.

6.

HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants.

Nguyen A, Ho L, Workenhe ST, Chen L, Samson J, Walsh SR, Pol J, Bramson JL, Wan Y.

Cell Rep. 2018 Jul 17;24(3):642-654. doi: 10.1016/j.celrep.2018.06.040.

7.

Expanded CD56superbrightCD16+ NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model.

Poznanski SM, Nham T, Chew MV, Lee AJ, Hammill JA, Fan IY, Butcher M, Bramson JL, Lee DA, Hirte HW, Ashkar AA.

Cancer Immunol Res. 2018 Oct;6(10):1174-1185. doi: 10.1158/2326-6066.CIR-18-0144. Epub 2018 Jul 17.

PMID:
30018043
8.

Adaptive Resistance to Cancer Immunotherapy.

McGray AJR, Bramson J.

Adv Exp Med Biol. 2017;1036:213-227. doi: 10.1007/978-3-319-67577-0_14. Review.

PMID:
29275474
9.

Serum C-Reactive Protein and Congestive Heart Failure as Significant Predictors of Herpes Zoster Vaccine Response in Elderly Nursing Home Residents.

Verschoor CP, Lelic A, Parsons R, Evelegh C, Bramson JL, Johnstone J, Loeb MB, Bowdish DME.

J Infect Dis. 2017 Jul 15;216(2):191-197. doi: 10.1093/infdis/jix257.

10.

AMPK β1 reduces tumor progression and improves survival in p53 null mice.

Houde VP, Donzelli S, Sacconi A, Galic S, Hammill JA, Bramson JL, Foster RA, Tsakiridis T, Kemp BE, Grasso G, Blandino G, Muti P, Steinberg GR.

Mol Oncol. 2017 Sep;11(9):1143-1155. doi: 10.1002/1878-0261.12079. Epub 2017 Jun 28.

11.

Kaiso depletion attenuates the growth and survival of triple negative breast cancer cells.

Bassey-Archibong BI, Rayner LG, Hercules SM, Aarts CW, Dvorkin-Gheva A, Bramson JL, Hassell JA, Daniel JM.

Cell Death Dis. 2017 Mar 23;8(3):e2689. doi: 10.1038/cddis.2017.92.

12.

Tumor-targeting domains for chimeric antigen receptor T cells.

Bezverbnaya K, Mathews A, Sidhu J, Helsen CW, Bramson JL.

Immunotherapy. 2017 Jan;9(1):33-46. doi: 10.2217/imt-2016-0103. Review.

PMID:
28000526
13.

T-Cell Phenotypes Predictive of Frailty and Mortality in Elderly Nursing Home Residents.

Johnstone J, Parsons R, Botelho F, Millar J, McNeil S, Fulop T, McElhaney JE, Andrew MK, Walter SD, Devereaux PJ, Malek M, Brinkman RR, Bramson J, Loeb M.

J Am Geriatr Soc. 2017 Jan;65(1):153-159. doi: 10.1111/jgs.14507. Epub 2016 Oct 24.

PMID:
27775813
14.

Immunogenicity of Varicella Vaccine and Immunologic Predictors of Response in a Cohort of Elderly Nursing Home Residents.

Lelic A, Verschoor CP, Lau VW, Parsons R, Evelegh C, Bowdish DM, Bramson JL, Loeb MB.

J Infect Dis. 2016 Dec 15;214(12):1905-1910. Epub 2016 Oct 5.

PMID:
27707807
15.

Induction of an Immune-Protective T-Cell Repertoire With Diverse Genetic Coverage by a Novel Viral-Vectored Tuberculosis Vaccine in Humans.

Jeyanathan M, Damjanovic D, Yao Y, Bramson J, Smaill F, Xing Z.

J Infect Dis. 2016 Dec 15;214(12):1996-2005. Epub 2016 Oct 4.

16.

Viral Engineering of Chimeric Antigen Receptor Expression on Murine and Human T Lymphocytes.

Hammill JA, Afsahi A, Bramson JL, Helsen CW.

Methods Mol Biol. 2016;1458:137-57. doi: 10.1007/978-1-4939-3801-8_11.

PMID:
27581020
17.

Characterization of Proliferating Lesion-Resident Cells During All Stages of Atherosclerotic Growth.

Lhoták Š, Gyulay G, Cutz JC, Al-Hashimi A, Trigatti BL, Richards CD, Igdoura SA, Steinberg GR, Bramson J, Ask K, Austin RC.

J Am Heart Assoc. 2016 Aug 15;5(8). pii: e003945. doi: 10.1161/JAHA.116.003945.

18.

Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells.

Provine NM, Larocca RA, Aid M, Penaloza-MacMaster P, Badamchi-Zadeh A, Borducchi EN, Yates KB, Abbink P, Kirilova M, Ng'ang'a D, Bramson J, Haining WN, Barouch DH.

J Immunol. 2016 Sep 1;197(5):1809-22. doi: 10.4049/jimmunol.1600591. Epub 2016 Jul 22.

19.

Correction: Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence.

Ananth AA, Tai LH, Lansdell C, Alkayyal AA, Baxter KE, Angka L, Zhang J, de Souza CT, Stephenson KB, Parato K, Bramson JL, Bell JC, Lichty BD, Auer RC.

PLoS One. 2016 Jul 18;11(7):e0159471. doi: 10.1371/journal.pone.0159471. eCollection 2016.

20.

Correction: Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway.

Anipindi VC, Bagri P, Roth K, Dizzell SE, Nguyen PV, Shaler CR, Chu DK, Jiménez-Saiz R, Liang H, Swift SL, Nazli A, Kafka JK, Bramson J, Xing Z, Jordana M, Wan Y, Snider DP, Stampfli MR, Kaushic C.

PLoS Pathog. 2016 Jun 8;12(6):e1005706. doi: 10.1371/journal.ppat.1005706. eCollection 2016 Jun.

21.

Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence.

Ananth AA, Tai LH, Lansdell C, Alkayyal AA, Baxter KE, Angka L, Zhang J, Tanese de Souza C, Stephenson KB, Parato K, Bramson JL, Bell JC, Lichty BD, Auer RC.

PLoS One. 2016 May 19;11(5):e0155947. doi: 10.1371/journal.pone.0155947. eCollection 2016. Erratum in: PLoS One. 2016;11(7):e0159471.

22.

Privileged Antigen Presentation in Splenic B Cell Follicles Maximizes T Cell Responses in Prime-Boost Vaccination.

Bridle BW, Nguyen A, Salem O, Zhang L, Koshy S, Clouthier D, Chen L, Pol J, Swift SL, Bowdish DM, Lichty BD, Bramson JL, Wan Y.

J Immunol. 2016 Jun 1;196(11):4587-95. doi: 10.4049/jimmunol.1600106. Epub 2016 Apr 27.

23.

Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway.

Anipindi VC, Bagri P, Roth K, Dizzell SE, Nguyen PV, Shaler CR, Chu DK, Jiménez-Saiz R, Liang H, Swift S, Nazli A, Kafka JK, Bramson J, Xing Z, Jordana M, Wan Y, Snider DP, Stampfli MR, Kaushic C.

PLoS Pathog. 2016 May 5;12(5):e1005589. doi: 10.1371/journal.ppat.1005589. eCollection 2016 May. Erratum in: PLoS Pathog. 2016 Jun;12(6):e1005706.

24.

Association of Interferon Regulatory Factor-4 Polymorphism rs12203592 With Divergent Melanoma Pathways.

Gibbs DC, Orlow I, Bramson JI, Kanetsky PA, Luo L, Kricker A, Armstrong BK, Anton-Culver H, Gruber SB, Marrett LD, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Sharma A, La Pilla E, From L, Busam KJ, Cust AE, Ollila DW, Begg CB, Berwick M, Thomas NE; GEM Study Group.

J Natl Cancer Inst. 2016 Feb 8;108(7). pii: djw004. doi: 10.1093/jnci/djw004. Print 2016 Jul.

25.

Designed ankyrin repeat proteins are effective targeting elements for chimeric antigen receptors.

Hammill JA, VanSeggelen H, Helsen CW, Denisova GF, Evelegh C, Tantalo DG, Bassett JD, Bramson JL.

J Immunother Cancer. 2015 Dec 15;3:55. doi: 10.1186/s40425-015-0099-4. eCollection 2015.

26.

An Introduction to Automated Flow Cytometry Gating Tools and Their Implementation.

Verschoor CP, Lelic A, Bramson JL, Bowdish DM.

Front Immunol. 2015 Jul 27;6:380. doi: 10.3389/fimmu.2015.00380. eCollection 2015. Review.

27.

Association Between NRAS and BRAF Mutational Status and Melanoma-Specific Survival Among Patients With Higher-Risk Primary Melanoma.

Thomas NE, Edmiston SN, Alexander A, Groben PA, Parrish E, Kricker A, Armstrong BK, Anton-Culver H, Gruber SB, From L, Busam KJ, Hao H, Orlow I, Kanetsky PA, Luo L, Reiner AS, Paine S, Frank JS, Bramson JI, Marrett LD, Gallagher RP, Zanetti R, Rosso S, Dwyer T, Cust AE, Ollila DW, Begg CB, Berwick M, Conway K; GEM Study Group.

JAMA Oncol. 2015 Jun;1(3):359-68. Erratum in: JAMA Oncol. 2015 Jun;1(3):285.

28.

T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice.

VanSeggelen H, Hammill JA, Dvorkin-Gheva A, Tantalo DG, Kwiecien JM, Denisova GF, Rabinovich B, Wan Y, Bramson JL.

Mol Ther. 2015 Oct;23(10):1600-10. doi: 10.1038/mt.2015.119. Epub 2015 Jun 30.

29.

Type I IFN signaling on dendritic cells is required for NK cell-mediated anti-tumor immunity.

Karimi K, Karimi Y, Chan J, Boudreau JE, Basset J, Chew MV, Reid S, Bramson JL, Wan Y, Ashkar AA.

Innate Immun. 2015 Aug;21(6):626-34. doi: 10.1177/1753425915575078. Epub 2015 Mar 5.

PMID:
25749844
30.

Circulating TNF and mitochondrial DNA are major determinants of neutrophil phenotype in the advanced-age, frail elderly.

Verschoor CP, Loukov D, Naidoo A, Puchta A, Johnstone J, Millar J, Lelic A, Novakowski KE, Dorrington MG, Loeb M, Bramson JL, Bowdish DM.

Mol Immunol. 2015 May;65(1):148-56. doi: 10.1016/j.molimm.2015.01.015. Epub 2015 Feb 5.

PMID:
25660689
31.

Chimeric antigen receptor-engineered T cells as oncolytic virus carriers.

VanSeggelen H, Tantalo DG, Afsahi A, Hammill JA, Bramson JL.

Mol Ther Oncolytics. 2015 Sep 9;2:15014. doi: 10.1038/mto.2015.14. eCollection 2015.

32.

Anti-pneumococcal deficits of monocyte-derived macrophages from the advanced-age, frail elderly and related impairments in PI3K-AKT signaling.

Verschoor CP, Johnstone J, Loeb M, Bramson JL, Bowdish DM.

Hum Immunol. 2014 Dec;75(12):1192-6. doi: 10.1016/j.humimm.2014.10.004. Epub 2014 Oct 13.

PMID:
25446401
33.

Circulating muramyl dipeptide is negatively associated with interleukin-10 in the frail elderly.

Verschoor CP, Naidoo A, Wallace JG, Johnstone J, Loeb M, Bramson JL, Bowdish DM.

Inflammation. 2015 Feb;38(1):272-7. doi: 10.1007/s10753-014-0030-z.

PMID:
25278013
34.

Immune biomarkers predictive of respiratory viral infection in elderly nursing home residents.

Johnstone J, Parsons R, Botelho F, Millar J, McNeil S, Fulop T, McElhaney J, Andrew MK, Walter SD, Devereaux PJ, Malekesmaeili M, Brinkman RR, Mahony J, Bramson J, Loeb M.

PLoS One. 2014 Oct 2;9(9):e108481. doi: 10.1371/journal.pone.0108481. eCollection 2014.

35.

Alterations to the frequency and function of peripheral blood monocytes and associations with chronic disease in the advanced-age, frail elderly.

Verschoor CP, Johnstone J, Millar J, Parsons R, Lelic A, Loeb M, Bramson JL, Bowdish DM.

PLoS One. 2014 Aug 8;9(8):e104522. doi: 10.1371/journal.pone.0104522. eCollection 2014.

36.

Analysis of purified wild type and mutant adenovirus particles by SILAC based quantitative proteomics.

Alqahtani A, Heesom K, Bramson JL, Curiel D, Ugai H, Matthews DA.

J Gen Virol. 2014 Nov;95(Pt 11):2504-11. doi: 10.1099/vir.0.068221-0. Epub 2014 Aug 5.

37.

Impact of periodontal therapy on general health: evidence from insurance data for five systemic conditions.

Jeffcoat MK, Jeffcoat RL, Gladowski PA, Bramson JB, Blum JJ.

Am J Prev Med. 2014 Aug;47(2):166-74. doi: 10.1016/j.amepre.2014.04.001. Epub 2014 Jun 18.

38.

Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop.

Chabierski S, Barzon L, Papa A, Niedrig M, Bramson JL, Richner JM, Palù G, Diamond MS, Ulbert S.

BMC Infect Dis. 2014 May 9;14:246. doi: 10.1186/1471-2334-14-246.

39.

T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes.

Chu DK, Mohammed-Ali Z, Jiménez-Saiz R, Walker TD, Goncharova S, Llop-Guevara A, Kong J, Gordon ME, Barra NG, Gillgrass AE, Van Seggelen H, Khan WI, Ashkar AA, Bramson JL, Humbles AA, Kolbeck R, Waserman S, Jordana M.

Mucosal Immunol. 2014 Nov;7(6):1395-404. doi: 10.1038/mi.2014.29. Epub 2014 Apr 30.

PMID:
24781052
40.

Immunosenescence in the nursing home elderly.

Johnstone J, Millar J, Lelic A, Verschoor CP, Walter SD, Devereaux PJ, Bramson J, Loeb M.

BMC Geriatr. 2014 Apr 17;14:50. doi: 10.1186/1471-2318-14-50.

41.

United Concordia's Utilization Review process.

Williamson JD, Bramson JB.

Pa Dent J (Harrisb). 2013 Nov-Dec;80(6):39-40. No abstract available.

PMID:
24600772
42.

Potential future elements of dental care financing--a third-party payer's perspective.

Manos PA, Bramson JB.

J Calif Dent Assoc. 2013 Dec;41(12):887-94.

PMID:
24597016
43.

Maraba virus as a potent oncolytic vaccine vector.

Pol JG, Zhang L, Bridle BW, Stephenson KB, Rességuier J, Hanson S, Chen L, Kazdhan N, Bramson JL, Stojdl DF, Wan Y, Lichty BD.

Mol Ther. 2014 Feb;22(2):420-429. doi: 10.1038/mt.2013.249. Epub 2013 Oct 25.

44.

Immunotherapy-induced CD8+ T cells instigate immune suppression in the tumor.

McGray AJ, Hallett R, Bernard D, Swift SL, Zhu Z, Teoderascu F, Vanseggelen H, Hassell JA, Hurwitz AA, Wan Y, Bramson JL.

Mol Ther. 2014 Jan;22(1):206-18. doi: 10.1038/mt.2013.255. Epub 2013 Oct 23.

45.

A human type 5 adenovirus-based tuberculosis vaccine induces robust T cell responses in humans despite preexisting anti-adenovirus immunity.

Smaill F, Jeyanathan M, Smieja M, Medina MF, Thanthrige-Don N, Zganiacz A, Yin C, Heriazon A, Damjanovic D, Puri L, Hamid J, Xie F, Foley R, Bramson J, Gauldie J, Xing Z.

Sci Transl Med. 2013 Oct 2;5(205):205ra134. doi: 10.1126/scitranslmed.3006843.

46.

Oncolytic vesicular stomatitis virus quantitatively and qualitatively improves primary CD8+ T-cell responses to anticancer vaccines.

Bridle BW, Clouthier D, Zhang L, Pol J, Chen L, Lichty BD, Bramson JL, Wan Y.

Oncoimmunology. 2013 Aug 1;2(8):e26013. Epub 2013 Aug 27.

47.

Blood CD33(+)HLA-DR(-) myeloid-derived suppressor cells are increased with age and a history of cancer.

Verschoor CP, Johnstone J, Millar J, Dorrington MG, Habibagahi M, Lelic A, Loeb M, Bramson JL, Bowdish DM.

J Leukoc Biol. 2013 Apr;93(4):633-7. doi: 10.1189/jlb.0912461. Epub 2013 Jan 22.

48.

Delivery of viral-vectored vaccines by B cells represents a novel strategy to accelerate CD8(+) T-cell recall responses.

Zhang L, Bridle BW, Chen L, Pol J, Spaner D, Boudreau JE, Rosen A, Bassett JD, Lichty BD, Bramson JL, Wan Y.

Blood. 2013 Mar 28;121(13):2432-9. doi: 10.1182/blood-2012-06-438481. Epub 2013 Jan 16.

49.

HDAC inhibition suppresses primary immune responses, enhances secondary immune responses, and abrogates autoimmunity during tumor immunotherapy.

Bridle BW, Chen L, Lemay CG, Diallo JS, Pol J, Nguyen A, Capretta A, He R, Bramson JL, Bell JC, Lichty BD, Wan Y.

Mol Ther. 2013 Apr;21(4):887-94. doi: 10.1038/mt.2012.265. Epub 2013 Jan 8.

50.

The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age.

Lelic A, Verschoor CP, Ventresca M, Parsons R, Evelegh C, Bowdish D, Betts MR, Loeb MB, Bramson JL.

PLoS Pathog. 2012;8(12):e1003076. doi: 10.1371/journal.ppat.1003076. Epub 2012 Dec 13.

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