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Items: 17


Targeting Hepatitis B Virus Covalently Closed Circular DNA and Hepatitis B Virus X Protein: Recent Advances and New Approaches.

Prescott NA, Bram Y, Schwartz RE, David Y.

ACS Infect Dis. 2019 Oct 11;5(10):1657-1667. doi: 10.1021/acsinfecdis.9b00249. Epub 2019 Sep 27.


Analysis of Host Responses to Hepatitis B and Delta Viral Infections in a Micro-scalable Hepatic Co-culture System.

Winer BY, Gaska JM, Lipkowitz G, Bram Y, Parekh A, Parsons L, Leach R, Jindal R, Cho CH, Shrirao A, Novik E, Schwartz RE, Ploss A.

Hepatology. 2019 Jun 17. doi: 10.1002/hep.30815. [Epub ahead of print]


An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo.

Galassi TV, Jena PV, Shah J, Ao G, Molitor E, Bram Y, Frankel A, Park J, Jessurun J, Ory DS, Haimovitz-Friedman A, Roxbury D, Mittal J, Zheng M, Schwartz RE, Heller DA.

Sci Transl Med. 2018 Oct 3;10(461). pii: eaar2680. doi: 10.1126/scitranslmed.aar2680.


Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection.

Winer BY, Shirvani-Dastgerdi E, Bram Y, Sellau J, Low BE, Johnson H, Huang T, Hrebikova G, Heller B, Sharon Y, Giersch K, Gerges S, Seneca K, Pais MA, Frankel AS, Chiriboga L, Cullen J, Nahass RG, Lutgehetmann M, Toettcher JE, Wiles MV, Schwartz RE, Ploss A.

Sci Transl Med. 2018 Jun 27;10(447). pii: eaap9328. doi: 10.1126/scitranslmed.aap9328.


Identification of the Intragenomic Promoter Controlling Hepatitis E Virus Subgenomic RNA Transcription.

Ding Q, Nimgaonkar I, Archer NF, Bram Y, Heller B, Schwartz RE, Ploss A.

mBio. 2018 May 8;9(3). pii: e00769-18. doi: 10.1128/mBio.00769-18.


Active Immunization Against hIAPP Oligomers Ameliorates the Diabetes- Associated Phenotype in a Transgenic Mice Model.

Bram Y, Peled S, Brahmachari S, Harlev M, Gazit E.

Sci Rep. 2017 Oct 25;7(1):14031. doi: 10.1038/s41598-017-14311-1.


Single cell imaging and quantification of TDP-43 and α-synuclein intercellular propagation.

Peled S, Sade D, Bram Y, Porat Z, Kreiser T, Mimouni M, Lichtenstein A, Segal D, Gazit E.

Sci Rep. 2017 Mar 28;7(1):544. doi: 10.1038/s41598-017-00657-z.


Formation of multimeric antibodies for self-delivery of active monomers.

Dekel Y, Machluf Y, Gefen T, Eidelshtein G, Kotlyar A, Bram Y, Shahar E, Reslane F, Aizenshtein E, Pitcovski J.

Drug Deliv. 2017 Nov;24(1):199-208. doi: 10.1080/10717544.2016.1242179.


Pluripotent Stem Cell-Derived Hepatocyte-like Cells: A Tool to Study Infectious Disease.

Schwartz RE, Bram Y, Frankel A.

Curr Pathobiol Rep. 2016 Sep;4(3):147-156. Epub 2016 Jul 30.


Formation of functional super-helical assemblies by constrained single heptad repeat.

Mondal S, Adler-Abramovich L, Lampel A, Bram Y, Lipstman S, Gazit E.

Nat Commun. 2015 Oct 15;6:8615. doi: 10.1038/ncomms9615.


Targeting the Early Step of Building Block Organization in Viral Capsid Assembly.

Lampel A, Bram Y, Ezer A, Shaltiel-Kario R, Saad JS, Bacharach E, Gazit E.

ACS Chem Biol. 2015 Aug 21;10(8):1785-90. doi: 10.1021/acschembio.5b00347. Epub 2015 May 29.


Monitoring and targeting the initial dimerization stage of amyloid self-assembly.

Bram Y, Lampel A, Shaltiel-Karyo R, Ezer A, Scherzer-Attali R, Segal D, Gazit E.

Angew Chem Int Ed Engl. 2015 Feb 9;54(7):2062-7. doi: 10.1002/anie.201408744. Epub 2014 Dec 22.


Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers.

Levin A, Mason TO, Adler-Abramovich L, Buell AK, Meisl G, Galvagnion C, Bram Y, Stratford SA, Dobson CM, Knowles TP, Gazit E.

Nat Commun. 2014 Nov 13;5:5219. doi: 10.1038/ncomms6219.


Apoptosis induced by islet amyloid polypeptide soluble oligomers is neutralized by diabetes-associated specific antibodies.

Bram Y, Frydman-Marom A, Yanai I, Gilead S, Shaltiel-Karyo R, Amdursky N, Gazit E.

Sci Rep. 2014 Mar 4;4:4267. doi: 10.1038/srep04267.


The effect of chemical chaperones on the assembly and stability of HIV-1 capsid protein.

Lampel A, Bram Y, Levy-Sakin M, Bacharach E, Gazit E.

PLoS One. 2013;8(4):e60867. doi: 10.1371/journal.pone.0060867. Epub 2013 Apr 5.


Cognitive-performance recovery of Alzheimer's disease model mice by modulation of early soluble amyloidal assemblies.

Frydman-Marom A, Rechter M, Shefler I, Bram Y, Shalev DE, Gazit E.

Angew Chem Int Ed Engl. 2009;48(11):1981-6. doi: 10.1002/anie.200802123.


Structural and thermodynamic characterization of the Escherichia coli RelBE toxin-antitoxin system: indication for a functional role of differential stability.

Cherny I, Overgaard M, Borch J, Bram Y, Gerdes K, Gazit E.

Biochemistry. 2007 Oct 30;46(43):12152-63. Epub 2007 Oct 9.


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