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Items: 22


Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.

Lee OW, Austin S, Gamma M, Cheff DM, Lee TD, Wilson KM, Johnson J, Travers J, Braisted JC, Guha R, Klumpp-Thomas C, Shen M, Hall MD.

SLAS Discov. 2019 Sep 9:2472555219873068. doi: 10.1177/2472555219873068. [Epub ahead of print]


DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer.

Meng Y, Chen CW, Yung MMH, Sun W, Sun J, Li Z, Li J, Li Z, Zhou W, Liu SS, Cheung ANY, Ngan HYS, Braisted JC, Kai Y, Peng W, Tzatsos A, Li Y, Dai Z, Zheng W, Chan DW, Zhu W.

Cancer Lett. 2018 Aug 1;428:104-116. doi: 10.1016/j.canlet.2018.04.029. Epub 2018 Apr 26.


Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance.

Zhou W, Sun W, Yung MMH, Dai S, Cai Y, Chen CW, Meng Y, Lee JB, Braisted JC, Xu Y, Southall NT, Shinn P, Huang X, Song Z, Chen X, Kai Y, Cai X, Li Z, Hao Q, Cheung ANY, Ngan HYS, Liu SS, Barak S, Hao J, Dai Z, Tzatsos A, Peng W, Pei H, Han Z, Chan DW, Zheng W, Zhu W.

Oncogene. 2018 Jul;37(29):3981-3997. doi: 10.1038/s41388-018-0238-8. Epub 2018 Apr 17.


The Toxmatrix: Chemo-Genomic Profiling Identifies Interactions That Reveal Mechanisms of Toxicity.

Tong ZB, Huang R, Wang Y, Klumpp-Thomas CA, Braisted JC, Itkin Z, Shinn P, Xia M, Simeonov A, Gerhold DL.

Chem Res Toxicol. 2018 Feb 19;31(2):127-136. doi: 10.1021/acs.chemrestox.7b00290. Epub 2017 Dec 4.


Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration-Approved Drugs.

Coussens NP, Braisted JC, Peryea T, Sittampalam GS, Simeonov A, Hall MD.

Pharmacol Rev. 2017 Oct;69(4):479-496. doi: 10.1124/pr.117.013755. Review.


Fluorescence polarization assays in high-throughput screening and drug discovery: a review.

Hall MD, Yasgar A, Peryea T, Braisted JC, Jadhav A, Simeonov A, Coussens NP.

Methods Appl Fluoresc. 2016 Apr 28;4(2):022001. doi: 10.1088/2050-6120/4/2/022001.


BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types.

Howe EA, de Souza A, Lahr DL, Chatwin S, Montgomery P, Alexander BR, Nguyen DT, Cruz Y, Stonich DA, Walzer G, Rose JT, Picard SC, Liu Z, Rose JN, Xiang X, Asiedu J, Durkin D, Levine J, Yang JJ, Schürer SC, Braisted JC, Southall N, Southern MR, Chung TD, Brudz S, Tanega C, Schreiber SL, Bittker JA, Guha R, Clemons PA.

Nucleic Acids Res. 2015 Jan;43(Database issue):D1163-70. doi: 10.1093/nar/gku1244. Epub 2014 Dec 4.


Proteomic View of Interactions of Shiga Toxin-Producing Escherichia coli with the Intestinal Environment in Gnotobiotic Piglets.

Pieper R, Zhang Q, Clark DJ, Parmar PP, Alami H, Suh MJ, Kuntumalla S, Braisted JC, Huang ST, Tzipori S.

PLoS One. 2013 Jun 19;8(6):e66462. doi: 10.1371/journal.pone.0066462. Print 2013.


Characterizing the Escherichia coli O157:H7 proteome including protein associations with higher order assemblies.

Pieper R, Zhang Q, Clark DJ, Huang ST, Suh MJ, Braisted JC, Payne SH, Fleischmann RD, Peterson SN, Tzipori S.

PLoS One. 2011;6(11):e26554. doi: 10.1371/journal.pone.0026554. Epub 2011 Nov 7.


In vivo versus in vitro protein abundance analysis of Shigella dysenteriae type 1 reveals changes in the expression of proteins involved in virulence, stress and energy metabolism.

Kuntumalla S, Zhang Q, Braisted JC, Fleischmann RD, Peterson SN, Donohue-Rolfe A, Tzipori S, Pieper R.

BMC Microbiol. 2011 Jun 24;11:147. doi: 10.1186/1471-2180-11-147.


Investigating the genome diversity of B. cereus and evolutionary aspects of B. anthracis emergence.

Papazisi L, Rasko DA, Ratnayake S, Bock GR, Remortel BG, Appalla L, Liu J, Dracheva T, Braisted JC, Shallom S, Jarrahi B, Snesrud E, Ahn S, Sun Q, Rilstone J, Okstad OA, Kolstø AB, Fleischmann RD, Peterson SN.

Genomics. 2011 Jul;98(1):26-39. doi: 10.1016/j.ygeno.2011.03.008. Epub 2011 Apr 5.


Role of luxS in Bacillus anthracis growth and virulence factor expression.

Jones MB, Peterson SN, Benn R, Braisted JC, Jarrahi B, Shatzkes K, Ren D, Wood TK, Blaser MJ.

Virulence. 2010 Mar-Apr;1(2):72-83. doi: 10.4161/viru.1.2.10752. Erratum in: Virulence. 2011 Mar-Apr;2(2):172.


Comparison of two label-free global quantitation methods, APEX and 2D gel electrophoresis, applied to the Shigella dysenteriae proteome.

Kuntumalla S, Braisted JC, Huang ST, Parmar PP, Clark DJ, Alami H, Zhang Q, Donohue-Rolfe A, Tzipori S, Fleischmann RD, Peterson SN, Pieper R.

Proteome Sci. 2009 Jun 29;7:22. doi: 10.1186/1477-5956-7-22.


The APEX Quantitative Proteomics Tool: generating protein quantitation estimates from LC-MS/MS proteomics results.

Braisted JC, Kuntumalla S, Vogel C, Marcotte EM, Rodrigues AR, Wang R, Huang ST, Ferlanti ES, Saeed AI, Fleischmann RD, Peterson SN, Pieper R.

BMC Bioinformatics. 2008 Dec 9;9:529. doi: 10.1186/1471-2105-9-529.


Proteomic analysis of laser-captured paraffin-embedded tissues: a molecular portrait of head and neck cancer progression.

Patel V, Hood BL, Molinolo AA, Lee NH, Conrads TP, Braisted JC, Krizman DB, Veenstra TD, Gutkind JS.

Clin Cancer Res. 2008 Feb 15;14(4):1002-14. doi: 10.1158/1078-0432.CCR-07-1497.


Identification of Pax5 as a target of MTA1 in B-cell lymphomas.

Balasenthil S, Gururaj AE, Talukder AH, Bagheri-Yarmand R, Arrington T, Haas BJ, Braisted JC, Kim I, Lee NH, Kumar R.

Cancer Res. 2007 Aug 1;67(15):7132-8. Erratum in: Cancer Res. 2015 Jun 15;75(12):2580-1.


TM4 microarray software suite.

Saeed AI, Bhagabati NK, Braisted JC, Liang W, Sharov V, Howe EA, Li J, Thiagarajan M, White JA, Quackenbush J.

Methods Enzymol. 2006;411:134-93. Review.


Attenuation of brain hyperbaric oxygen toxicity by fasting is not related to ketosis.

Chavko M, Braisted JC, Harabin AL.

Undersea Hyperb Med. 1999 Summer;26(2):99-103.


Effect of MK-801 on seizures induced by exposure to hyperbaric oxygen: comparison with AP-7.

Chavko M, Braisted JC, Harabin AL.

Toxicol Appl Pharmacol. 1998 Aug;151(2):222-8.


Role of cerebral blood flow in seizures from hyperbaric oxygen exposure.

Chavko M, Braisted JC, Outsa NJ, Harabin AL.

Brain Res. 1998 Apr 27;791(1-2):75-82.


Response of antioxidant enzymes to intermittent and continuous hyperbaric oxygen.

Harabin AL, Braisted JC, Flynn ET.

J Appl Physiol (1985). 1990 Jul;69(1):328-35.


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