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Items: 40


Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.

Lee OW, Austin S, Gamma M, Cheff DM, Lee TD, Wilson KM, Johnson J, Travers J, Braisted JC, Guha R, Klumpp-Thomas C, Shen M, Hall MD.

SLAS Discov. 2020 Jan;25(1):9-20. doi: 10.1177/2472555219873068. Epub 2019 Sep 9.


Inhibition of natriuretic peptide receptor 1 reduces itch in mice.

Solinski HJ, Dranchak P, Oliphant E, Gu X, Earnest TW, Braisted J, Inglese J, Hoon MA.

Sci Transl Med. 2019 Jul 10;11(500). pii: eaav5464. doi: 10.1126/scitranslmed.aav5464.


Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.

Miller TW, Amason JD, Garcin ED, Lamy L, Dranchak PK, Macarthur R, Braisted J, Rubin JS, Burgess TL, Farrell CL, Roberts DD, Inglese J.

PLoS One. 2019 Jul 5;14(7):e0218897. doi: 10.1371/journal.pone.0218897. eCollection 2019.


DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer.

Meng Y, Chen CW, Yung MMH, Sun W, Sun J, Li Z, Li J, Li Z, Zhou W, Liu SS, Cheung ANY, Ngan HYS, Braisted JC, Kai Y, Peng W, Tzatsos A, Li Y, Dai Z, Zheng W, Chan DW, Zhu W.

Cancer Lett. 2018 Aug 1;428:104-116. doi: 10.1016/j.canlet.2018.04.029. Epub 2018 Apr 26.


Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance.

Zhou W, Sun W, Yung MMH, Dai S, Cai Y, Chen CW, Meng Y, Lee JB, Braisted JC, Xu Y, Southall NT, Shinn P, Huang X, Song Z, Chen X, Kai Y, Cai X, Li Z, Hao Q, Cheung ANY, Ngan HYS, Liu SS, Barak S, Hao J, Dai Z, Tzatsos A, Peng W, Pei H, Han Z, Chan DW, Zheng W, Zhu W.

Oncogene. 2018 Jul;37(29):3981-3997. doi: 10.1038/s41388-018-0238-8. Epub 2018 Apr 17.


The Toxmatrix: Chemo-Genomic Profiling Identifies Interactions That Reveal Mechanisms of Toxicity.

Tong ZB, Huang R, Wang Y, Klumpp-Thomas CA, Braisted JC, Itkin Z, Shinn P, Xia M, Simeonov A, Gerhold DL.

Chem Res Toxicol. 2018 Feb 19;31(2):127-136. doi: 10.1021/acs.chemrestox.7b00290. Epub 2017 Dec 4.


Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration-Approved Drugs.

Coussens NP, Braisted JC, Peryea T, Sittampalam GS, Simeonov A, Hall MD.

Pharmacol Rev. 2017 Oct;69(4):479-496. doi: 10.1124/pr.117.013755. Review.


A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives.

Grimm FA, Iwata Y, Sirenko O, Chappell GA, Wright FA, Reif DM, Braisted J, Gerhold DL, Yeakley JM, Shepard P, Seligmann B, Roy T, Boogaard PJ, Ketelslegers HB, Rohde AM, Rusyn I.

Green Chem. 2016 Aug 21;18(16):4407-4419. doi: 10.1039/c6gc01147k. Epub 2016 May 16.


Fluorescence polarization assays in high-throughput screening and drug discovery: a review.

Hall MD, Yasgar A, Peryea T, Braisted JC, Jadhav A, Simeonov A, Coussens NP.

Methods Appl Fluoresc. 2016 Apr 28;4(2):022001. doi: 10.1088/2050-6120/4/2/022001.


BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types.

Howe EA, de Souza A, Lahr DL, Chatwin S, Montgomery P, Alexander BR, Nguyen DT, Cruz Y, Stonich DA, Walzer G, Rose JT, Picard SC, Liu Z, Rose JN, Xiang X, Asiedu J, Durkin D, Levine J, Yang JJ, Schürer SC, Braisted JC, Southall N, Southern MR, Chung TD, Brudz S, Tanega C, Schreiber SL, Bittker JA, Guha R, Clemons PA.

Nucleic Acids Res. 2015 Jan;43(Database issue):D1163-70. doi: 10.1093/nar/gku1244. Epub 2014 Dec 4.


Proteomic View of Interactions of Shiga Toxin-Producing Escherichia coli with the Intestinal Environment in Gnotobiotic Piglets.

Pieper R, Zhang Q, Clark DJ, Parmar PP, Alami H, Suh MJ, Kuntumalla S, Braisted JC, Huang ST, Tzipori S.

PLoS One. 2013 Jun 19;8(6):e66462. doi: 10.1371/journal.pone.0066462. Print 2013.


nEASE: a method for gene ontology subclassification of high-throughput gene expression data.

Chittenden TW, Howe EA, Taylor JM, Mar JC, Aryee MJ, Gómez H, Sultana R, Braisted J, Nair SJ, Quackenbush J, Holmes C.

Bioinformatics. 2012 Mar 1;28(5):726-8. doi: 10.1093/bioinformatics/bts011. Epub 2012 Jan 13.


Characterizing the Escherichia coli O157:H7 proteome including protein associations with higher order assemblies.

Pieper R, Zhang Q, Clark DJ, Huang ST, Suh MJ, Braisted JC, Payne SH, Fleischmann RD, Peterson SN, Tzipori S.

PLoS One. 2011;6(11):e26554. doi: 10.1371/journal.pone.0026554. Epub 2011 Nov 7.


In vivo versus in vitro protein abundance analysis of Shigella dysenteriae type 1 reveals changes in the expression of proteins involved in virulence, stress and energy metabolism.

Kuntumalla S, Zhang Q, Braisted JC, Fleischmann RD, Peterson SN, Donohue-Rolfe A, Tzipori S, Pieper R.

BMC Microbiol. 2011 Jun 24;11:147. doi: 10.1186/1471-2180-11-147.


Investigating the genome diversity of B. cereus and evolutionary aspects of B. anthracis emergence.

Papazisi L, Rasko DA, Ratnayake S, Bock GR, Remortel BG, Appalla L, Liu J, Dracheva T, Braisted JC, Shallom S, Jarrahi B, Snesrud E, Ahn S, Sun Q, Rilstone J, Okstad OA, Kolstø AB, Fleischmann RD, Peterson SN.

Genomics. 2011 Jul;98(1):26-39. doi: 10.1016/j.ygeno.2011.03.008. Epub 2011 Apr 5.


Role of luxS in Bacillus anthracis growth and virulence factor expression.

Jones MB, Peterson SN, Benn R, Braisted JC, Jarrahi B, Shatzkes K, Ren D, Wood TK, Blaser MJ.

Virulence. 2010 Mar-Apr;1(2):72-83. doi: 10.4161/viru.1.2.10752. Erratum in: Virulence. 2011 Mar-Apr;2(2):172.


Compton suppression method and epithermal NAA in the determination of nutrients and heavy metals in Nigerian food and beverages.

Ahmed YA, Landsberger S, O'Kelly DJ, Braisted J, Gabdo H, Ewa IO, Umar IM, Funtua II.

Appl Radiat Isot. 2010 Oct;68(10):1909-14. doi: 10.1016/j.apradiso.2010.04.016. Epub 2010 Apr 18.


Comparison of two label-free global quantitation methods, APEX and 2D gel electrophoresis, applied to the Shigella dysenteriae proteome.

Kuntumalla S, Braisted JC, Huang ST, Parmar PP, Clark DJ, Alami H, Zhang Q, Donohue-Rolfe A, Tzipori S, Fleischmann RD, Peterson SN, Pieper R.

Proteome Sci. 2009 Jun 29;7:22. doi: 10.1186/1477-5956-7-22.


Slits are chemorepellents endogenous to hypothalamus and steer thalamocortical axons into ventral telencephalon.

Braisted JE, Ringstedt T, O'Leary DD.

Cereb Cortex. 2009 Jul;19 Suppl 1:i144-51. doi: 10.1093/cercor/bhp035. Epub 2009 May 11.


The APEX Quantitative Proteomics Tool: generating protein quantitation estimates from LC-MS/MS proteomics results.

Braisted JC, Kuntumalla S, Vogel C, Marcotte EM, Rodrigues AR, Wang R, Huang ST, Ferlanti ES, Saeed AI, Fleischmann RD, Peterson SN, Pieper R.

BMC Bioinformatics. 2008 Dec 9;9:529. doi: 10.1186/1471-2105-9-529.


Proteomic analysis of laser-captured paraffin-embedded tissues: a molecular portrait of head and neck cancer progression.

Patel V, Hood BL, Molinolo AA, Lee NH, Conrads TP, Braisted JC, Krizman DB, Veenstra TD, Gutkind JS.

Clin Cancer Res. 2008 Feb 15;14(4):1002-14. doi: 10.1158/1078-0432.CCR-07-1497.


Identification of Pax5 as a target of MTA1 in B-cell lymphomas.

Balasenthil S, Gururaj AE, Talukder AH, Bagheri-Yarmand R, Arrington T, Haas BJ, Braisted JC, Kim I, Lee NH, Kumar R.

Cancer Res. 2007 Aug 1;67(15):7132-8. Erratum in: Cancer Res. 2015 Jun 15;75(12):2580-1.


TM4 microarray software suite.

Saeed AI, Bhagabati NK, Braisted JC, Liang W, Sharov V, Howe EA, Li J, Thiagarajan M, White JA, Quackenbush J.

Methods Enzymol. 2006;411:134-93. Review.


Measurement of brain electrical impedance: animal studies in rheoencephalography.

Bodo M, Pearce FJ, Montgomery LD, Rosenthal M, Kubinyi G, Thuroczy G, Braisted J, Forcino D, Morrissette C, Nagy I.

Aviat Space Environ Med. 2003 May;74(5):506-11.


TM4: a free, open-source system for microarray data management and analysis.

Saeed AI, Sharov V, White J, Li J, Liang W, Bhagabati N, Braisted J, Klapa M, Currier T, Thiagarajan M, Sturn A, Snuffin M, Rezantsev A, Popov D, Ryltsov A, Kostukovich E, Borisovsky I, Liu Z, Vinsavich A, Trush V, Quackenbush J.

Biotechniques. 2003 Feb;34(2):374-8. No abstract available.


Netrin-1 promotes thalamic axon growth and is required for proper development of the thalamocortical projection.

Braisted JE, Catalano SM, Stimac R, Kennedy TE, Tessier-Lavigne M, Shatz CJ, O'Leary DD.

J Neurosci. 2000 Aug 1;20(15):5792-801.


Slit inhibition of retinal axon growth and its role in retinal axon pathfinding and innervation patterns in the diencephalon.

Ringstedt T, Braisted JE, Brose K, Kidd T, Goodman C, Tessier-Lavigne M, O'Leary DD.

J Neurosci. 2000 Jul 1;20(13):4983-91.


Attenuation of brain hyperbaric oxygen toxicity by fasting is not related to ketosis.

Chavko M, Braisted JC, Harabin AL.

Undersea Hyperb Med. 1999 Summer;26(2):99-103.


Effect of MK-801 on seizures induced by exposure to hyperbaric oxygen: comparison with AP-7.

Chavko M, Braisted JC, Harabin AL.

Toxicol Appl Pharmacol. 1998 Aug;151(2):222-8.


Role of cerebral blood flow in seizures from hyperbaric oxygen exposure.

Chavko M, Braisted JC, Outsa NJ, Harabin AL.

Brain Res. 1998 Apr 27;791(1-2):75-82.


Retinal axon guidance by region-specific cues in diencephalon.

Tuttle R, Braisted JE, Richards LJ, O'Leary DD.

Development. 1998 Mar;125(5):791-801.


Graded and lamina-specific distributions of ligands of EphB receptor tyrosine kinases in the developing retinotectal system.

Braisted JE, McLaughlin T, Wang HU, Friedman GC, Anderson DJ, O'leary DD.

Dev Biol. 1997 Nov 1;191(1):14-28.


Selective regeneration of photoreceptors in goldfish retina.

Braisted JE, Essman TF, Raymond PA.

Development. 1994 Sep;120(9):2409-19.


Regeneration of dopaminergic neurons in goldfish retina.

Braisted JE, Raymond PA.

Development. 1992 Apr;114(4):913-9.


Response of antioxidant enzymes to intermittent and continuous hyperbaric oxygen.

Harabin AL, Braisted JC, Flynn ET.

J Appl Physiol (1985). 1990 Jul;69(1):328-35.


The adolescent ballet dancer. Nutritional practices and characteristics associated with anorexia nervosa.

Braisted JR, Mellin L, Gong EJ, Irwin CE Jr.

J Adolesc Health Care. 1985 Sep;6(5):365-71.


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