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Items: 45

1.

Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation.

Brahimi-Horn MC, Giuliano S, Saland E, Lacas-Gervais S, Sheiko T, Pelletier J, Bourget I, Bost F, Féral C, Boulter E, Tauc M, Ivan M, Garmy-Susini B, Popa A, Mari B, Sarry JE, Craigen WJ, Pouysségur J, Mazure NM.

Cancer Metab. 2015 Aug 26;3:8. doi: 10.1186/s40170-015-0133-5. eCollection 2015.

2.

Local mitochondrial-endolysosomal microfusion cleaves voltage-dependent anion channel 1 to promote survival in hypoxia.

Brahimi-Horn MC, Lacas-Gervais S, Adaixo R, Ilc K, Rouleau M, Notte A, Dieu M, Michiels C, Voeltzel T, Maguer-Satta V, Pelletier J, Ilie M, Hofman P, Manoury B, Schmidt A, Hiller S, Pouysségur J, Mazure NM.

Mol Cell Biol. 2015 May;35(9):1491-505. doi: 10.1128/MCB.01402-14. Epub 2015 Feb 17.

3.

Hypoxic VDAC1: a potential mitochondrial marker for cancer therapy.

Brahimi-Horn MC, Mazure NM.

Adv Exp Med Biol. 2014;772:101-10. doi: 10.1007/978-1-4614-5915-6_5. Review.

PMID:
24272356
4.

Expression of a truncated active form of VDAC1 in lung cancer associates with hypoxic cell survival and correlates with progression to chemotherapy resistance.

Brahimi-Horn MC, Ben-Hail D, Ilie M, Gounon P, Rouleau M, Hofman V, Doyen J, Mari B, Shoshan-Barmatz V, Hofman P, Pouysségur J, Mazure NM.

Cancer Res. 2012 Apr 15;72(8):2140-50. doi: 10.1158/0008-5472.CAN-11-3940. Epub 2012 Mar 2.

5.

Inactivation of androgen-induced regulator ARD1 inhibits androgen receptor acetylation and prostate tumorigenesis.

Wang Z, Wang Z, Guo J, Li Y, Bavarva JH, Qian C, Brahimi-Horn MC, Tan D, Liu W.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3053-8. doi: 10.1073/pnas.1113356109. Epub 2012 Feb 6.

6.

Hypoxic mitochondria: accomplices in resistance.

Mazure NM, Brahimi-Horn MC, Pouysségur J.

Bull Cancer. 2011 May;98(5):40-6. doi: 10.1684/bdc.2011.1360. Review.

7.

Hypoxia and energetic tumour metabolism.

Brahimi-Horn MC, Bellot G, Pouysségur J.

Curr Opin Genet Dev. 2011 Feb;21(1):67-72. doi: 10.1016/j.gde.2010.10.006. Epub 2010 Nov 11. Review.

PMID:
21074987
8.

Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.

Chiche J, Brahimi-Horn MC, Pouysségur J.

J Cell Mol Med. 2010 Apr;14(4):771-94. doi: 10.1111/j.1582-4934.2009.00994.x. Epub 2009 Dec 8. Review.

9.

Hypoxic enlarged mitochondria protect cancer cells from apoptotic stimuli.

Chiche J, Rouleau M, Gounon P, Brahimi-Horn MC, Pouysségur J, Mazure NM.

J Cell Physiol. 2010 Mar;222(3):648-57. doi: 10.1002/jcp.21984.

PMID:
19957303
10.

Membrane-bound carbonic anhydrases are key pH regulators controlling tumor growth and cell migration.

Chiche J, Ilc K, Brahimi-Horn MC, Pouysségur J.

Adv Enzyme Regul. 2010;50(1):20-33. doi: 10.1016/j.advenzreg.2009.10.005. Epub 2009 Nov 4. Review. No abstract available.

PMID:
19895836
11.

Highlights of the European Association of Cancer Research (EACR 2008).

Brahimi-Horn MC, Pouysségur J.

Bull Cancer. 2009 Apr;96(4):485-99. doi: 10.1684/bdc.2009.0799.

12.

HIF at a glance.

Brahimi-Horn MC, Pouysségur J.

J Cell Sci. 2009 Apr 15;122(Pt 8):1055-7. doi: 10.1242/jcs.035022. Review. No abstract available.

13.

A dialogue between the hypoxia-inducible factor and the tumor microenvironment.

Dayan F, Mazure NM, Brahimi-Horn MC, Pouysségur J.

Cancer Microenviron. 2008 Dec;1(1):53-68. doi: 10.1007/s12307-008-0006-3. Epub 2008 Mar 19.

14.

Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.

Chiche J, Ilc K, Laferrière J, Trottier E, Dayan F, Mazure NM, Brahimi-Horn MC, Pouysségur J.

Cancer Res. 2009 Jan 1;69(1):358-68. doi: 10.1158/0008-5472.CAN-08-2470.

15.

Hypoxia and cancer.

Brahimi-Horn MC, Chiche J, Pouysségur J.

J Mol Med (Berl). 2007 Dec;85(12):1301-7. Epub 2007 Nov 20. Review.

PMID:
18026916
16.

Immunologic profile and outcome of childhood acute lymphoblastic leukemia (ALL) in Morocco.

Dakka N, Bellaoui H, Khattab M, Brahimi-Horn MC, Aoued L, Bouzid N, Bakri Y, Benjouad A.

J Pediatr Hematol Oncol. 2007 Aug;29(8):574-80.

PMID:
17762501
17.

Hypoxia in cancer cell metabolism and pH regulation.

Brahimi-Horn MC, Pouysségur J.

Essays Biochem. 2007;43:165-78. Review.

PMID:
17705800
18.

SUMOylation of hypoxia-inducible factor-1alpha reduces its transcriptional activity.

Berta MA, Mazure N, Hattab M, Pouysségur J, Brahimi-Horn MC.

Biochem Biophys Res Commun. 2007 Aug 31;360(3):646-52. Epub 2007 Jun 27.

PMID:
17610843
19.

Oxygen, a source of life and stress.

Brahimi-Horn MC, Pouysségur J.

FEBS Lett. 2007 Jul 31;581(19):3582-91. Epub 2007 Jun 19. Review.

20.

Hypoxia signalling controls metabolic demand.

Brahimi-Horn MC, Chiche J, Pouysségur J.

Curr Opin Cell Biol. 2007 Apr;19(2):223-9. Epub 2007 Feb 15. Review.

PMID:
17303407
21.

Harnessing the hypoxia-inducible factor in cancer and ischemic disease.

Brahimi-Horn MC, Pouysségur J.

Biochem Pharmacol. 2007 Feb 1;73(3):450-7. Epub 2006 Oct 20. Review.

PMID:
17101119
22.

ARDent about acetylation and deacetylation in hypoxia signalling.

Bilton R, Trottier E, Pouysségur J, Brahimi-Horn MC.

Trends Cell Biol. 2006 Dec;16(12):616-21. Epub 2006 Oct 27.

PMID:
17070052
24.

Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF.

Bilton R, Mazure N, Trottier E, Hattab M, Déry MA, Richard DE, Pouysségur J, Brahimi-Horn MC.

J Biol Chem. 2005 Sep 2;280(35):31132-40. Epub 2005 Jul 1. Erratum in: J Biol Chem. 2006 Jun 2;281(22):15592.

25.

The hypoxia-inducible factor and tumor progression along the angiogenic pathway.

Brahimi-Horn MC, Pouysségur J.

Int Rev Cytol. 2005;242:157-213. Review.

PMID:
15598469
26.

HIF-1: master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs.

Mazure NM, Brahimi-Horn MC, Berta MA, Benizri E, Bilton RL, Dayan F, Ginouvès A, Berra E, Pouysségur J.

Biochem Pharmacol. 2004 Sep 15;68(6):971-80. Review.

PMID:
15313390
27.

Ventilatory responses to hypercapnia and hypoxia in conscious cystic fibrosis knockout mice Cftr-/-.

Bonora M, Bernaudin JF, Guernier C, Brahimi-Horn MC.

Pediatr Res. 2004 May;55(5):738-46. Epub 2004 Feb 5.

PMID:
14764916
28.

Protein kinases and the hypoxia-inducible factor-1, two switches in angiogenesis.

Mazure NM, Brahimi-Horn MC, Pouysségur J.

Curr Pharm Des. 2003;9(7):531-41. Review.

PMID:
12570801
29.

Gene transfer by adenovirus-mimetic peptides in the presence of a cationic lipid and/or adenovirus. Analysis of the contribution of the viral and nonviral components.

Moritz S, Colin M, Keller M, Klonjkowski B, Capeau J, Coutelle C, Chroboczek J, Brahimi-Horn MC.

Arch Virol. 2003 Jan;148(1):1-18.

PMID:
12536292
30.

Characterisation of LMD virus-like nanoparticles self-assembled from cationic liposomes, adenovirus core peptide mu and plasmid DNA.

Tagawa T, Manvell M, Brown N, Keller M, Perouzel E, Murray KD, Harbottle RP, Tecle M, Booy F, Brahimi-Horn MC, Coutelle C, Lemoine NR, Alton EW, Miller AD.

Gene Ther. 2002 May;9(9):564-76.

31.

The nuclear pore complex is involved in nuclear transfer of plasmid DNA condensed with an oligolysine-RGD peptide containing nuclear localisation properties.

Colin M, Moritz S, Fontanges P, Kornprobst M, Delouis C, Keller M, Miller AD, Capeau J, Coutelle C, Brahimi-Horn MC.

Gene Ther. 2001 Nov;8(21):1643-53.

32.

Glycoconjugate metabolism in a cystic fibrosis knockout mouse model.

Mailleau C, Paul A, Colin M, Xing PX, Guernier C, Bernaudin JF, Capeau J, Brahimi-Horn MC.

Mol Genet Metab. 2001 Feb;72(2):122-31.

PMID:
11161838
33.

Haemoglobin interferes with the ex vivo luciferase luminescence assay: consequence for detection of luciferase reporter gene expression in vivo.

Colin M, Moritz S, Schneider H, Capeau J, Coutelle C, Brahimi-Horn MC.

Gene Ther. 2000 Aug;7(15):1333-6.

34.

Cell delivery, intracellular trafficking and expression of an integrin-mediated gene transfer vector in tracheal epithelial cells.

Colin M, Maurice M, Trugnan G, Kornprobst M, Harbottle RP, Knight A, Cooper RG, Miller AD, Capeau J, Coutelle C, Brahimi-Horn MC.

Gene Ther. 2000 Jan;7(2):139-52.

35.

Liposomes enhance delivery and expression of an RGD-oligolysine gene transfer vector in human tracheal cells.

Colin M, Harbottle RP, Knight A, Kornprobst M, Cooper RG, Miller AD, Trugnan G, Capeau J, Coutelle C, Brahimi-Horn MC.

Gene Ther. 1998 Nov;5(11):1488-98.

36.

Interrelationship between the Na+/glucose cotransporter and CFTR in Caco-2 cells: relevance to cystic fibrosis.

Mailleau C, Capeau J, Brahimi-Horn MC.

J Cell Physiol. 1998 Sep;176(3):472-81.

PMID:
9699500
37.

CFTR gene transfer corrects defective glycoconjugate secretion in human CF epithelial tracheal cells.

Mergey M, Lemnaouar M, Veissiere D, Perricaudet M, Gruenert DC, Picard J, Capeau J, Brahimi-Horn MC, Paul A.

Am J Physiol. 1995 Dec;269(6 Pt 1):L855-64.

PMID:
8572248
38.

Identification of decorin proteoglycan in bovine tracheal serous cells in culture and localization of decorin mRNA in situ.

Brahimi-Horn MC, Deudon E, Paul A, Mergey M, Mailleau C, Basbaum C, Dohrman A, Capeau J.

Eur J Cell Biol. 1994 Aug;64(2):271-80.

PMID:
7813515
39.

Synthesis of hydrolytic enzymes during production of tylosin by Streptomyces fradiae.

Brahimi-Horn MC, Luo SH, Wang SL, Gau SW, Mou DG.

J Ind Microbiol. 1992 Jul;10(1):25-30.

PMID:
1381591
40.

Nondenaturing protein electrotransfer of the esterase activity of lipolytic preparations.

Brahimi-Horn MC, Guglielmino ML, Gaal AM, Sparrow LG.

Anal Biochem. 1991 Jul;196(1):76-9.

PMID:
1888039
41.

The esterase profile of a lipase from Candida cylindracea.

Brahimi-Horn MC, Guglielmino ML, Elling L, Sparrow LG.

Biochim Biophys Acta. 1990 Jan 16;1042(1):51-4.

PMID:
2297523
42.

Lipolytic enzymes of the digestive organs of the crown-of-thorns starfish (Acanthaster planci): comparison of the stomach and pyloric caeca.

Brahimi-Horn MC, Guglielmino ML, Sparrow LG, Logan RI, Moran PJ.

Comp Biochem Physiol B. 1989;92(4):637-43.

PMID:
2721155
43.

Effect of insulin on sulfated proteoglycan synthesis in cultured smooth muscle cells from pig aorta.

Breton M, Berrou E, Deudon E, Brahimi-Horn MC, Picard J.

Exp Cell Res. 1988 Jul;177(1):212-20.

PMID:
3292273
44.

Characterization and macromolecular association of proteoglycans produced by pig arterial smooth muscle cells in culture.

Deudon E, Brahimi-Horn MC, Breton M, Berrou E, Picard J.

Int J Biochem. 1988;20(4):397-407.

PMID:
3366298
45.

Synthesis of sulfated proteoglycans throughout the cell cycle in smooth muscle cells from pig aorta.

Breton M, Berrou E, Brahimi-Horn MC, Deudon E, Picard J.

Exp Cell Res. 1986 Oct;166(2):416-26.

PMID:
3743663

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