Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 143

1.

EGF Treatment Improves Motor Behavior and Cortical GABAergic Function in the R6/2 Mouse Model of Huntington's Disease.

Marottoli FM, Priego M, Flores-Barrera E, Pisharody R, Zaldua S, Fan KD, Ekkurthi GK, Brady ST, Morfini GA, Tseng KY, Tai LM.

Mol Neurobiol. 2019 May 19. doi: 10.1007/s12035-019-1634-y. [Epub ahead of print]

PMID:
31104296
2.

Detection of axonal degeneration in a mouse model of Huntington's disease: comparison between diffusion tensor imaging and anomalous diffusion metrics.

Gatto RG, Ye AQ, Colon-Perez L, Mareci TH, Lysakowski A, Price SD, Brady ST, Karaman M, Morfini G, Magin RL.

MAGMA. 2019 Aug;32(4):461-471. doi: 10.1007/s10334-019-00742-6. Epub 2019 Feb 15.

PMID:
30771034
3.

Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2.

Zamponi E, Buratti F, Cataldi G, Caicedo HH, Song Y, Jungbauer LM, LaDu MJ, Bisbal M, Lorenzo A, Ma J, Helguera PR, Morfini GA, Brady ST, Pigino GF.

PLoS One. 2017 Dec 20;12(12):e0188340. doi: 10.1371/journal.pone.0188340. eCollection 2017.

4.

Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases.

Brady ST, Morfini GA.

Neurobiol Dis. 2017 Sep;105:273-282. doi: 10.1016/j.nbd.2017.04.010. Epub 2017 Apr 11. Review.

5.

Mutant spastin proteins promote deficits in axonal transport through an isoform-specific mechanism involving casein kinase 2 activation.

Leo L, Weissmann C, Burns M, Kang M, Song Y, Qiang L, Brady ST, Baas PW, Morfini G.

Hum Mol Genet. 2017 Jun 15;26(12):2321-2334. doi: 10.1093/hmg/ddx125.

6.

ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation.

Sama RR, Fallini C, Gatto R, McKeon JE, Song Y, Rotunno MS, Penaranda S, Abdurakhmanov I, Landers JE, Morfini G, Brady ST, Bosco DA.

Sci Rep. 2017 Mar 8;7(1):115. doi: 10.1038/s41598-017-00091-1.

7.

HIV Glycoprotein Gp120 Impairs Fast Axonal Transport by Activating Tak1 Signaling Pathways.

Berth SH, Mesnard-Hoaglin N, Wang B, Kim H, Song Y, Sapar M, Morfini G, Brady ST.

ASN Neuro. 2016 Nov 20;8(6). pii: 1759091416679073. Print 2016 Dec.

8.

Analysis of isoform-specific tau aggregates suggests a common toxic mechanism involving similar pathological conformations and axonal transport inhibition.

Cox K, Combs B, Abdelmesih B, Morfini G, Brady ST, Kanaan NM.

Neurobiol Aging. 2016 Nov;47:113-126. doi: 10.1016/j.neurobiolaging.2016.07.015. Epub 2016 Jul 29.

9.

Is Axonal Degeneration a Key Early Event in Parkinson's Disease?

Kurowska Z, Kordower JH, Stoessl AJ, Burke RE, Brundin P, Yue Z, Brady ST, Milbrandt J, Trapp BD, Sherer TB, Medicetty S.

J Parkinsons Dis. 2016 Oct 19;6(4):703-707. Review.

PMID:
27497486
10.

Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport.

Tiernan CT, Combs B, Cox K, Morfini G, Brady ST, Counts SE, Kanaan NM.

Exp Neurol. 2016 Sep;283(Pt A):318-29. doi: 10.1016/j.expneurol.2016.06.030. Epub 2016 Jun 30.

11.

Teaching a lay theory before college narrows achievement gaps at scale.

Yeager DS, Walton GM, Brady ST, Akcinar EN, Paunesku D, Keane L, Kamentz D, Ritter G, Duckworth AL, Urstein R, Gomez EM, Markus HR, Cohen GL, Dweck CS.

Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):E3341-8. doi: 10.1073/pnas.1524360113. Epub 2016 May 31.

12.

Tau pathology-mediated presynaptic dysfunction.

Moreno H, Morfini G, Buitrago L, Ujlaki G, Choi S, Yu E, Moreira JE, Avila J, Brady ST, Pant H, Sugimori M, Llinás RR.

Neuroscience. 2016 Jun 14;325:30-8. doi: 10.1016/j.neuroscience.2016.03.044. Epub 2016 Mar 21.

13.

Fast axonal transport in isolated axoplasm from the squid giant axon.

Song Y, Kang M, Morfini G, Brady ST.

Methods Cell Biol. 2016;131:331-48. doi: 10.1016/bs.mcb.2015.07.004. Epub 2015 Sep 2.

PMID:
26794522
14.

Biochemical analysis of axon-specific phosphorylation events using isolated squid axoplasms.

Kang M, Baker L, Song Y, Brady ST, Morfini G.

Methods Cell Biol. 2016;131:199-216. doi: 10.1016/bs.mcb.2015.06.003. Epub 2015 Sep 2.

PMID:
26794515
15.

Microfluidics: The Challenge Is to Bridge the Gap Instead of Looking for a 'Killer App'.

Caicedo HH, Brady ST.

Trends Biotechnol. 2016 Jan;34(1):1-3. doi: 10.1016/j.tibtech.2015.10.003. Epub 2015 Nov 18. No abstract available.

PMID:
26603287
16.

Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease.

Gatto RG, Chu Y, Ye AQ, Price SD, Tavassoli E, Buenaventura A, Brady ST, Magin RL, Kordower JH, Morfini GA.

Hum Mol Genet. 2015 Sep 15;24(18):5285-98. doi: 10.1093/hmg/ddv248. Epub 2015 Jun 29.

17.

Internalization and axonal transport of the HIV glycoprotein gp120.

Berth S, Caicedo HH, Sarma T, Morfini G, Brady ST.

ASN Neuro. 2015 Jan 30;7(1). pii: 1759091414568186. doi: 10.1177/1759091414568186. Print 2015 Jan-Feb.

18.

Post-translational modifications of tubulin: pathways to functional diversity of microtubules.

Song Y, Brady ST.

Trends Cell Biol. 2015 Mar;25(3):125-36. doi: 10.1016/j.tcb.2014.10.004. Epub 2014 Nov 25. Review.

19.

Stabilization of neuronal connections and the axonal cytoskeleton.

Song Y, Brady ST.

Bioarchitecture. 2014 Jan-Feb;4(1):22-4. doi: 10.4161/bioa.28080. Epub 2014 Feb 3.

20.

The co-occurrence of myocardial dysfunction and peripheral insensate neuropathy in a streptozotocin-induced rat model of diabetes.

Marangoni MN, Brady ST, Chowdhury SA, Piano MR.

Cardiovasc Diabetol. 2014 Jan 11;13:11. doi: 10.1186/1475-2840-13-11.

21.

Analysis of microtubules in isolated axoplasm from the squid giant axon.

Song Y, Brady ST.

Methods Cell Biol. 2013;115:125-37. doi: 10.1016/B978-0-12-407757-7.00009-8.

22.

Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase.

Morfini GA, Bosco DA, Brown H, Gatto R, Kaminska A, Song Y, Molla L, Baker L, Marangoni MN, Berth S, Tavassoli E, Bagnato C, Tiwari A, Hayward LJ, Pigino GF, Watterson DM, Huang CF, Banker G, Brown RH Jr, Brady ST.

PLoS One. 2013 Jun 12;8(6):e65235. doi: 10.1371/journal.pone.0065235. Print 2013.

23.

The sphingolipid psychosine inhibits fast axonal transport in Krabbe disease by activation of GSK3β and deregulation of molecular motors.

Cantuti Castelvetri L, Givogri MI, Hebert A, Smith B, Song Y, Kaminska A, Lopez-Rosas A, Morfini G, Pigino G, Sands M, Brady ST, Bongarzone ER.

J Neurosci. 2013 Jun 12;33(24):10048-56. doi: 10.1523/JNEUROSCI.0217-13.2013.

24.

Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy.

LaPointe NE, Morfini G, Brady ST, Feinstein SC, Wilson L, Jordan MA.

Neurotoxicology. 2013 Jul;37:231-9. doi: 10.1016/j.neuro.2013.05.008. Epub 2013 May 24.

25.

Molecular mechanisms of environmental enrichment: impairments in Akt/GSK3β, neurotrophin-3 and CREB signaling.

Hu YS, Long N, Pigino G, Brady ST, Lazarov O.

PLoS One. 2013 May 21;8(5):e64460. doi: 10.1371/journal.pone.0064460. Print 2013.

26.

Transglutaminase and polyamination of tubulin: posttranslational modification for stabilizing axonal microtubules.

Song Y, Kirkpatrick LL, Schilling AB, Helseth DL, Chabot N, Keillor JW, Johnson GV, Brady ST.

Neuron. 2013 Apr 10;78(1):109-23. doi: 10.1016/j.neuron.2013.01.036.

27.

Molecular chaperone Hsp110 rescues a vesicle transport defect produced by an ALS-associated mutant SOD1 protein in squid axoplasm.

Song Y, Nagy M, Ni W, Tyagi NK, Fenton WA, López-Giráldez F, Overton JD, Horwich AL, Brady ST.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5428-33. doi: 10.1073/pnas.1303279110. Epub 2013 Mar 18.

28.

Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system.

Kanaan NM, Pigino GF, Brady ST, Lazarov O, Binder LI, Morfini GA.

Exp Neurol. 2013 Aug;246:44-53. doi: 10.1016/j.expneurol.2012.06.003. Epub 2012 Jun 19. Review.

29.

Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease.

Chu Y, Morfini GA, Langhamer LB, He Y, Brady ST, Kordower JH.

Brain. 2012 Jul;135(Pt 7):2058-73. doi: 10.1093/brain/aws133. Epub 2012 Jun 19.

30.

Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.

Patterson KR, Ward SM, Combs B, Voss K, Kanaan NM, Morfini G, Brady ST, Gamblin TC, Binder LI.

Biochemistry. 2011 Nov 29;50(47):10300-10. doi: 10.1021/bi2009147. Epub 2011 Nov 8.

31.

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.

Kanaan NM, Morfini G, Pigino G, LaPointe NE, Andreadis A, Song Y, Leitman E, Binder LI, Brady ST.

Neurobiol Aging. 2012 Apr;33(4):826.e15-30. doi: 10.1016/j.neurobiolaging.2011.06.006. Epub 2011 Jul 27.

32.

Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases.

Kanaan NM, Morfini GA, LaPointe NE, Pigino GF, Patterson KR, Song Y, Andreadis A, Fu Y, Brady ST, Binder LI.

J Neurosci. 2011 Jul 6;31(27):9858-68. doi: 10.1523/JNEUROSCI.0560-11.2011.

33.

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS.

Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH Jr.

Nat Neurosci. 2010 Nov;13(11):1396-403. doi: 10.1038/nn.2660. Epub 2010 Oct 17.

34.

Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.

Han I, You Y, Kordower JH, Brady ST, Morfini GA.

J Neurochem. 2010 Jun;113(5):1073-91. doi: 10.1111/j.1471-4159.2010.06672.x. Epub 2010 Mar 17. Review.

35.

Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 mice.

Hu YS, Xu P, Pigino G, Brady ST, Larson J, Lazarov O.

FASEB J. 2010 Jun;24(6):1667-81. doi: 10.1096/fj.09-136945. Epub 2010 Jan 19.

36.

Axonal transport defects in neurodegenerative diseases.

Morfini GA, Burns M, Binder LI, Kanaan NM, LaPointe N, Bosco DA, Brown RH Jr, Brown H, Tiwari A, Hayward L, Edgar J, Nave KA, Garberrn J, Atagi Y, Song Y, Pigino G, Brady ST.

J Neurosci. 2009 Oct 14;29(41):12776-86. doi: 10.1523/JNEUROSCI.3463-09.2009. Review.

37.

Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.

Morfini GA, You YM, Pollema SL, Kaminska A, Liu K, Yoshioka K, Björkblom B, Coffey ET, Bagnato C, Han D, Huang CF, Banker G, Pigino G, Brady ST.

Nat Neurosci. 2009 Jul;12(7):864-71. doi: 10.1038/nn.2346. Epub 2009 Jun 14.

38.

The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.

LaPointe NE, Morfini G, Pigino G, Gaisina IN, Kozikowski AP, Binder LI, Brady ST.

J Neurosci Res. 2009 Feb;87(2):440-51. doi: 10.1002/jnr.21850.

39.

Myelin sheaths are formed with proteins that originated in vertebrate lineages.

Gould RM, Oakley T, Goldstone JV, Dugas JC, Brady ST, Gow A.

Neuron Glia Biol. 2008 May;4(2):137-52. doi: 10.1017/S1740925X09990238.

40.

Conventional kinesin holoenzymes are composed of heavy and light chain homodimers.

DeBoer SR, You Y, Szodorai A, Kaminska A, Pigino G, Nwabuisi E, Wang B, Estrada-Hernandez T, Kins S, Brady ST, Morfini G.

Biochemistry. 2008 Apr 15;47(15):4535-43. doi: 10.1021/bi702445j. Epub 2008 Mar 25.

41.

Quantitative and functional analyses of spastin in the nervous system: implications for hereditary spastic paraplegia.

Solowska JM, Morfini G, Falnikar A, Himes BT, Brady ST, Huang D, Baas PW.

J Neurosci. 2008 Feb 27;28(9):2147-57. doi: 10.1523/JNEUROSCI.3159-07.2008.

42.

Approaches to kinesin-1 phosphorylation.

Morfini G, Pigino G, Brady ST.

Methods Mol Biol. 2007;392:51-69.

PMID:
17951710
43.

Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1.

Lazarov O, Morfini GA, Pigino G, Gadadhar A, Chen X, Robinson J, Ho H, Brady ST, Sisodia SS.

J Neurosci. 2007 Jun 27;27(26):7011-20.

44.

Cellular trafficking of phospholamban and formation of functional sarcoplasmic reticulum during myocyte differentiation.

Stenoien DL, Knyushko TV, Londono MP, Opresko LK, Mayer MU, Brady ST, Squier TC, Bigelow DJ.

Am J Physiol Cell Physiol. 2007 Jun;292(6):C2084-94. Epub 2007 Feb 7.

45.

1-Methyl-4-phenylpyridinium induces synaptic dysfunction through a pathway involving caspase and PKCdelta enzymatic activities.

Serulle Y, Morfini G, Pigino G, Moreira JE, Sugimori M, Brady ST, Llinás RR.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2437-41. Epub 2007 Feb 7.

46.

1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C.

Morfini G, Pigino G, Opalach K, Serulle Y, Moreira JE, Sugimori M, Llinás RR, Brady ST.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2442-7. Epub 2007 Feb 7.

47.

Tau binding to microtubules does not directly affect microtubule-based vesicle motility.

Morfini G, Pigino G, Mizuno N, Kikkawa M, Brady ST.

J Neurosci Res. 2007 Sep;85(12):2620-30.

PMID:
17265463
48.

JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport.

Morfini G, Pigino G, Szebenyi G, You Y, Pollema S, Brady ST.

Nat Neurosci. 2006 Jul;9(7):907-16. Epub 2006 Jun 4.

PMID:
16751763
49.

Gender differences in response of hippocampus to chronic glucocorticoid stress: role of glutamate receptors.

Liu HH, Payne HR, Wang B, Brady ST.

J Neurosci Res. 2006 Apr;83(5):775-86.

PMID:
16498614
50.

Activity-driven dendritic remodeling requires microtubule-associated protein 1A.

Szebenyi G, Bollati F, Bisbal M, Sheridan S, Faas L, Wray R, Haferkamp S, Nguyen S, Caceres A, Brady ST.

Curr Biol. 2005 Oct 25;15(20):1820-6.

Supplemental Content

Loading ...
Support Center