Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 134

1.

Granulocyte-Colony Stimulating Factor Alters the Pharmacodynamic Properties of Cocaine in Female Mice.

Brady LJ, Hofford RS, Tat J, Calipari ES, Kiraly DD.

ACS Chem Neurosci. 2019 Sep 11. doi: 10.1021/acschemneuro.9b00309. [Epub ahead of print]

PMID:
31479229
2.

Membrane proteomic analysis reveals overlapping and independent functions of Streptococcus mutans Ffh, YidC1, and YidC2.

Mishra S, Crowley PJ, Wright KR, Palmer SR, Walker AR, Datta S, Brady LJ.

Mol Oral Microbiol. 2019 Aug;34(4):131-152. doi: 10.1111/omi.12261. Epub 2019 Jun 7.

PMID:
31034136
3.

Disabling the Gβγ-SNARE interaction disrupts GPCR-mediated presynaptic inhibition, leading to physiological and behavioral phenotypes.

Zurawski Z, Thompson Gray AD, Brady LJ, Page B, Church E, Harris NA, Dohn MR, Yim YY, Hyde K, Mortlock DP, Jones CK, Winder DG, Alford S, Hamm HE.

Sci Signal. 2019 Feb 19;12(569). pii: eaat8595. doi: 10.1126/scisignal.aat8595.

PMID:
30783011
4.

The Biology of Streptococcus mutans.

Lemos JA, Palmer SR, Zeng L, Wen ZT, Kajfasz JK, Freires IA, Abranches J, Brady LJ.

Microbiol Spectr. 2019 Jan;7(1). doi: 10.1128/microbiolspec.GPP3-0051-2018.

5.

Biology of Oral Streptococci.

Abranches J, Zeng L, Kajfasz JK, Palmer SR, Chakraborty B, Wen ZT, Richards VP, Brady LJ, Lemos JA.

Microbiol Spectr. 2018 Oct;6(5). doi: 10.1128/microbiolspec.GPP3-0042-2018. Review.

6.

Streptococcus mutans yidC1 and yidC2 Impact Cell Envelope Biogenesis, the Biofilm Matrix, and Biofilm Biophysical Properties.

Palmer SR, Ren Z, Hwang G, Liu Y, Combs A, Söderström B, Lara Vasquez P, Khosravi Y, Brady LJ, Koo H, Stoodley P.

J Bacteriol. 2018 Dec 7;201(1). pii: e00396-18. doi: 10.1128/JB.00396-18. Print 2019 Jan 1.

7.

Granulocyte Colony Stimulating Factor Enhances Reward Learning through Potentiation of Mesolimbic Dopamine System Function.

Kutlu MG, Brady LJ, Peck EG, Hofford RS, Yorgason JT, Siciliano CA, Kiraly DD, Calipari ES.

J Neurosci. 2018 Oct 10;38(41):8845-8859. doi: 10.1523/JNEUROSCI.1116-18.2018. Epub 2018 Aug 27.

8.

Characterization of the pgf operon involved in the posttranslational modification of Streptococcus mutans surface proteins.

Avilés-Reyes A, Freires IA, Besingi R, Purushotham S, Deivanayagam C, Brady LJ, Abranches J, Lemos JA.

Sci Rep. 2018 Mar 16;8(1):4705. doi: 10.1038/s41598-018-23170-3.

9.

LT adjuvant modulates epitope specificity and improves the efficacy of murine antibodies elicited by sublingual vaccination with the N-terminal domain of Streptococcus mutans P1.

Batista MT, Ferreira EL, Pereira GS, Stafford P, Maeda DLNF, Rodrigues JF, Brady LJ, Johnston SA, Ferreira LCS, Ferreira RCC.

Vaccine. 2017 Dec 19;35(52):7273-7282. doi: 10.1016/j.vaccine.2017.11.007. Epub 2017 Nov 13.

PMID:
29146379
10.

Functional amyloids in Streptococcus mutans, their use as targets of biofilm inhibition and initial characterization of SMU_63c.

Besingi RN, Wenderska IB, Senadheera DB, Cvitkovitch DG, Long JR, Wen ZT, Brady LJ.

Microbiology. 2017 Apr;163(4):488-501. doi: 10.1099/mic.0.000443. Epub 2017 Apr 26.

11.

Transcriptional dysregulation causes altered modulation of inhibition by haloperidol.

Brady LJ, Bartley AF, Li Q, McMeekin LJ, Hablitz JJ, Cowell RM, Dobrunz LE.

Neuropharmacology. 2016 Dec;111:304-313. doi: 10.1016/j.neuropharm.2016.07.034. Epub 2016 Jul 29.

12.

Specific binding of a naturally occurring amyloidogenic fragment of Streptococcus mutans adhesin P1 to intact P1 on the cell surface characterized by solid state NMR spectroscopy.

Tang W, Bhatt A, Smith AN, Crowley PJ, Brady LJ, Long JR.

J Biomol NMR. 2016 Feb;64(2):153-64. doi: 10.1007/s10858-016-0017-1. Epub 2016 Feb 2.

13.

Trk2 Potassium Transport System in Streptococcus mutans and Its Role in Potassium Homeostasis, Biofilm Formation, and Stress Tolerance.

Binepal G, Gill K, Crowley P, Cordova M, Brady LJ, Senadheera DB, Cvitkovitch DG.

J Bacteriol. 2016 Jan 25;198(7):1087-100. doi: 10.1128/JB.00813-15.

14.

Interneuron Transcriptional Dysregulation Causes Frequency-Dependent Alterations in the Balance of Inhibition and Excitation in Hippocampus.

Bartley AF, Lucas EK, Brady LJ, Li Q, Hablitz JJ, Cowell RM, Dobrunz LE.

J Neurosci. 2015 Nov 18;35(46):15276-90. doi: 10.1523/JNEUROSCI.1834-15.2015.

15.
16.

Real-time product attribute control to manufacture antibodies with defined N-linked glycan levels.

Zupke C, Brady LJ, Slade PG, Clark P, Caspary RG, Livingston B, Taylor L, Bigham K, Morris AE, Bailey RW.

Biotechnol Prog. 2015 Sep-Oct;31(5):1433-41. doi: 10.1002/btpr.2136. Epub 2015 Jul 27.

PMID:
26179435
17.

The criticality of high-resolution N-linked carbohydrate assays and detailed characterization of antibody effector function in the context of biosimilar development.

Brady LJ, Velayudhan J, Visone DB, Daugherty KC, Bartron JL, Coon M, Cornwall C, Hinckley PJ, Connell-Crowley L.

MAbs. 2015;7(3):562-70. doi: 10.1080/19420862.2015.1016692.

18.

An optimized approach to the rapid assessment and detection of sequence variants in recombinant protein products.

Brady LJ, Scott RA, Balland A.

Anal Bioanal Chem. 2015 May;407(13):3851-60. doi: 10.1007/s00216-015-8618-1. Epub 2015 Mar 21.

PMID:
25795027
19.

Binding forces of Streptococcus mutans P1 adhesin.

Sullan RM, Li JK, Crowley PJ, Brady LJ, Dufrêne YF.

ACS Nano. 2015 Feb 24;9(2):1448-60. doi: 10.1021/nn5058886. Epub 2015 Feb 11.

20.

Identification of a supramolecular functional architecture of Streptococcus mutans adhesin P1 on the bacterial cell surface.

Heim KP, Sullan RM, Crowley PJ, El-Kirat-Chatel S, Beaussart A, Tang W, Besingi R, Dufrene YF, Brady LJ.

J Biol Chem. 2015 Apr 3;290(14):9002-19. doi: 10.1074/jbc.M114.626663. Epub 2015 Feb 9.

21.

Rapid identification of an antibody DNA construct rearrangement sequence variant by mass spectrometry.

Scott RA, Rogers R, Balland A, Brady LJ.

MAbs. 2014;6(6):1453-63. doi: 10.4161/mabs.36222.

22.

Breaking the bacterial protein targeting and translocation model: oral organisms as a case in point.

Lewis NE, Brady LJ.

Mol Oral Microbiol. 2015 Jun;30(3):186-97. doi: 10.1111/omi.12088. Epub 2014 Dec 26. Review.

23.

An intramolecular lock facilitates folding and stabilizes the tertiary structure of Streptococcus mutans adhesin P1.

Heim KP, Crowley PJ, Long JR, Kailasan S, McKenna R, Brady LJ.

Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15746-51. doi: 10.1073/pnas.1413018111. Epub 2014 Oct 20.

24.

Immunogenicity and in vitro and in vivo protective effects of antibodies targeting a recombinant form of the Streptococcus mutans P1 surface protein.

Batista MT, Souza RD, Ferreira EL, Robinette R, Crowley PJ, Rodrigues JF, Brady LJ, Ferreira LC, Ferreira RC.

Infect Immun. 2014 Dec;82(12):4978-88. doi: 10.1128/IAI.02074-14. Epub 2014 Sep 15.

25.

Streptococcus mutans extracellular DNA is upregulated during growth in biofilms, actively released via membrane vesicles, and influenced by components of the protein secretion machinery.

Liao S, Klein MI, Heim KP, Fan Y, Bitoun JP, Ahn SJ, Burne RA, Koo H, Brady LJ, Wen ZT.

J Bacteriol. 2014 Jul;196(13):2355-66. doi: 10.1128/JB.01493-14. Epub 2014 Apr 18.

26.

YlxM is a newly identified accessory protein that influences the function of signal recognition particle pathway components in Streptococcus mutans.

Williams ML, Crowley PJ, Hasona A, Brady LJ.

J Bacteriol. 2014 Jun;196(11):2043-52. doi: 10.1128/JB.01465-13. Epub 2014 Mar 21.

27.

Alterations in immunodominance of Streptococcus mutans AgI/II: lessons learned from immunomodulatory antibodies.

Robinette RA, Heim KP, Oli MW, Crowley PJ, McArthur WP, Brady LJ.

Vaccine. 2014 Jan 9;32(3):375-82. doi: 10.1016/j.vaccine.2013.11.023. Epub 2013 Nov 16.

28.

An intramolecular interaction involving the N terminus of a streptococcal adhesin affects its conformation and adhesive function.

Heim KP, Crowley PJ, Brady LJ.

J Biol Chem. 2013 May 10;288(19):13762-74. doi: 10.1074/jbc.M113.459974. Epub 2013 Mar 28.

29.

Functional amyloid formation by Streptococcus mutans.

Oli MW, Otoo HN, Crowley PJ, Heim KP, Nascimento MM, Ramsook CB, Lipke PN, Brady LJ.

Microbiology. 2012 Dec;158(Pt 12):2903-16. doi: 10.1099/mic.0.060855-0. Epub 2012 Oct 18.

30.

YidC1 and YidC2 are functionally distinct proteins involved in protein secretion, biofilm formation and cariogenicity of Streptococcus mutans.

Palmer SR, Crowley PJ, Oli MW, Ruelf MA, Michalek SM, Brady LJ.

Microbiology. 2012 Jul;158(Pt 7):1702-12. doi: 10.1099/mic.0.059139-0. Epub 2012 Apr 13.

31.

BrpA is involved in regulation of cell envelope stress responses in Streptococcus mutans.

Bitoun JP, Liao S, Yao X, Ahn SJ, Isoda R, Nguyen AH, Brady LJ, Burne RA, Abranches J, Wen ZT.

Appl Environ Microbiol. 2012 Apr;78(8):2914-22. doi: 10.1128/AEM.07823-11. Epub 2012 Feb 10.

32.

A therapeutic anti-Streptococcus mutans monoclonal antibody used in human passive protection trials influences the adaptive immune response.

Robinette RA, Oli MW, McArthur WP, Brady LJ.

Vaccine. 2011 Aug 26;29(37):6292-300. doi: 10.1016/j.vaccine.2011.06.027. Epub 2011 Jun 23.

33.

Crystal structure of the C-terminal region of Streptococcus mutans antigen I/II and characterization of salivary agglutinin adherence domains.

Larson MR, Rajashankar KR, Crowley PJ, Kelly C, Mitchell TJ, Brady LJ, Deivanayagam C.

J Biol Chem. 2011 Jun 17;286(24):21657-66. doi: 10.1074/jbc.M111.231100. Epub 2011 Apr 19.

34.

The changing faces of Streptococcus antigen I/II polypeptide family adhesins.

Brady LJ, Maddocks SE, Larson MR, Forsgren N, Persson K, Deivanayagam CC, Jenkinson HF.

Mol Microbiol. 2010 Jul;77(2):276-86. doi: 10.1111/j.1365-2958.2010.07212.x. Epub 2010 May 24. Review.

35.

Induction of neutralizing antibodies in mice immunized with an amino-terminal polypeptide of Streptococcus mutans P1 protein produced by a recombinant Bacillus subtilis strain.

Tavares MB, Silva BM, Cavalcante RC, Souza RD, Luiz WB, Paccez JD, Crowley PJ, Brady LJ, Ferreira LC, Ferreira RC.

FEMS Immunol Med Microbiol. 2010 Jul 1;59(2):131-42. doi: 10.1111/j.1574-695X.2010.00669.x. Epub 2010 Mar 10.

36.

Characterization of antibody charge heterogeneity resolved by preparative immobilized pH gradients.

Meert CD, Brady LJ, Guo A, Balland A.

Anal Chem. 2010 May 1;82(9):3510-8. doi: 10.1021/ac902408r.

PMID:
20364842
37.

Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of alpha- and PPII-helices.

Larson MR, Rajashankar KR, Patel MH, Robinette RA, Crowley PJ, Michalek S, Brady LJ, Deivanayagam C.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5983-8. doi: 10.1073/pnas.0912293107. Epub 2010 Mar 15.

38.

Asparagine-linked oligosaccharides present on a non-consensus amino acid sequence in the CH1 domain of human antibodies.

Valliere-Douglass JF, Kodama P, Mujacic M, Brady LJ, Wang W, Wallace A, Yan B, Reddy P, Treuheit MJ, Balland A.

J Biol Chem. 2009 Nov 20;284(47):32493-506. doi: 10.1074/jbc.M109.014803. Epub 2009 Sep 18.

39.

Beneficial immunomodulation by Streptococcus mutans anti-P1 monoclonal antibodies is Fc independent and correlates with increased exposure of a relevant target epitope.

Robinette RA, Oli MW, McArthur WP, Brady LJ.

J Immunol. 2009 Oct 1;183(7):4628-38. doi: 10.4049/jimmunol.0803300. Epub 2009 Sep 14. Erratum in: J Immunol. 2009 Nov 15;183(10):6849.

40.

Independent gene duplications of the YidC/Oxa/Alb3 family enabled a specialized cotranslational function.

Funes S, Hasona A, Bauerschmitt H, Grubbauer C, Kauff F, Collins R, Crowley PJ, Palmer SR, Brady LJ, Herrmann JM.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6656-61. doi: 10.1073/pnas.0809951106. Epub 2009 Apr 6.

41.

O-fucosylation of an antibody light chain: characterization of a modification occurring on an IgG1 molecule.

Valliere-Douglass JF, Brady LJ, Farnsworth C, Pace D, Balland A, Wallace A, Wang W, Treuheit MJ, Yan B.

Glycobiology. 2009 Feb;19(2):144-52. doi: 10.1093/glycob/cwn116. Epub 2008 Oct 24.

PMID:
18952827
42.

Characteristics of biofilm formation by Streptococcus mutans in the presence of saliva.

Ahn SJ, Ahn SJ, Wen ZT, Brady LJ, Burne RA.

Infect Immun. 2008 Sep;76(9):4259-68. doi: 10.1128/IAI.00422-08. Epub 2008 Jul 14.

43.

Isolation and solubilization of cellular membrane proteins from bacteria.

Zuobi-Hasona K, Brady LJ.

Methods Mol Biol. 2008;425:287-93. doi: 10.1007/978-1-60327-210-0_23.

PMID:
18369904
44.

Requirements for surface expression and function of adhesin P1 from Streptococcus mutans.

Crowley PJ, Seifert TB, Isoda R, van Tilburg M, Oli MW, Robinette RA, McArthur WP, Bleiweis AS, Brady LJ.

Infect Immun. 2008 Jun;76(6):2456-68. doi: 10.1128/IAI.01315-07. Epub 2008 Mar 24.

45.

Molecular mass analysis of antibodies by on-line SEC-MS.

Brady LJ, Valliere-Douglass J, Martinez T, Balland A.

J Am Soc Mass Spectrom. 2008 Apr;19(4):502-9. doi: 10.1016/j.jasms.2007.12.006. Epub 2008 Jan 4.

46.

Functional overlap but lack of complete cross-complementation of Streptococcus mutans and Escherichia coli YidC orthologs.

Dong Y, Palmer SR, Hasona A, Nagamori S, Kaback HR, Dalbey RE, Brady LJ.

J Bacteriol. 2008 Apr;190(7):2458-69. doi: 10.1128/JB.01366-07. Epub 2008 Jan 4.

47.

Consequences of a sortase A mutation in Streptococcus gordonii.

Nobbs AH, Vajna RM, Johnson JR, Zhang Y, Erlandsen SL, Oli MW, Kreth J, Brady LJ, Herzberg MC.

Microbiology. 2007 Dec;153(Pt 12):4088-97.

PMID:
18048922
48.

Characterization of nonenzymatic glycation on a monoclonal antibody.

Brady LJ, Martinez T, Balland A.

Anal Chem. 2007 Dec 15;79(24):9403-13. Epub 2007 Nov 7.

PMID:
17985928
49.

Basis of beneficial immunomodulation by monoclonal antibodies against Streptococcus mutans adhesin P1.

Isoda R, Robinette RA, Pinder TL, McArthur WP, Brady LJ.

FEMS Immunol Med Microbiol. 2007 Oct;51(1):102-11. Epub 2007 Jul 5.

50.

Supplemental Content

Loading ...
Support Center