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Items: 1 to 50 of 141

1.

Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission.

Chevalier SA, Turpin J, Cachat A, Afonso PV, Gessain A, Brady JN, Pise-Masison CA, Mahieux R.

PLoS Pathog. 2014 Feb 27;10(2):e1003917. doi: 10.1371/journal.ppat.1003917. eCollection 2014 Feb.

2.

The transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties.

Chevalier SA, Durand S, Dasgupta A, Radonovich M, Cimarelli A, Brady JN, Mahieux R, Pise-Masison CA.

PLoS One. 2012;7(7):e41003. doi: 10.1371/journal.pone.0041003. Epub 2012 Jul 20.

3.

Inhibition of geranylgeranyl transferase-I decreases cell viability of HTLV-1-transformed cells.

Edwards DC, McKinnon KM, Fenizia C, Jung KJ, Brady JN, Pise-Masison CA.

Viruses. 2011 Oct;3(10):1815-35. doi: 10.3390/v3101815. Epub 2011 Oct 10.

4.

Human T-lymphotropic virus type 1 Tax protein complexes with P-TEFb and competes for Brd4 and 7SK snRNP/HEXIM1 binding.

Cho WK, Jang MK, Huang K, Pise-Masison CA, Brady JN.

J Virol. 2010 Dec;84(24):12801-9. doi: 10.1128/JVI.00943-10. Epub 2010 Oct 6.

5.

Human T-lymphotropic virus type 1 transcription and chromatin-remodeling complexes.

Easley R, Carpio L, Guendel I, Klase Z, Choi S, Kehn-Hall K, Brady JN, Kashanchi F.

J Virol. 2010 May;84(9):4755-68. doi: 10.1128/JVI.00851-09. Epub 2010 Feb 17.

6.

NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein.

Journo C, Filipe J, About F, Chevalier SA, Afonso PV, Brady JN, Flynn D, Tangy F, Israël A, Vidalain PO, Mahieux R, Weil R.

PLoS Pathog. 2009 Jul;5(7):e1000521. doi: 10.1371/journal.ppat.1000521. Epub 2009 Jul 17.

7.

Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability.

Pise-Masison CA, Radonovich M, Dohoney K, Morris JC, O'Mahony D, Lee MJ, Trepel J, Waldmann TA, Janik JE, Brady JN.

Blood. 2009 Apr 23;113(17):4016-26. doi: 10.1182/blood-2008-08-175901. Epub 2009 Jan 8.

8.

Gene regulation and functional alterations induced by Kaposi's sarcoma-associated herpesvirus-encoded ORFK13/vFLIP in endothelial cells.

Sakakibara S, Pise-Masison CA, Brady JN, Tosato G.

J Virol. 2009 Mar;83(5):2140-53. doi: 10.1128/JVI.01871-08. Epub 2008 Dec 17.

9.

Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29.

Zhou M, Huang K, Jung KJ, Cho WK, Klase Z, Kashanchi F, Pise-Masison CA, Brady JN.

J Virol. 2009 Jan;83(2):1036-44. doi: 10.1128/JVI.01316-08. Epub 2008 Oct 29.

10.

Small-molecule inhibitor which reactivates p53 in human T-cell leukemia virus type 1-transformed cells.

Jung KJ, Dasgupta A, Huang K, Jeong SJ, Pise-Masison C, Gurova KV, Brady JN.

J Virol. 2008 Sep;82(17):8537-47. doi: 10.1128/JVI.00690-08. Epub 2008 Jun 11.

11.

Construction and characterization of a human T-cell lymphotropic virus type 3 infectious molecular clone.

Chevalier SA, Ko NL, Calattini S, Mallet A, Prévost MC, Kehn K, Brady JN, Kashanchi F, Gessain A, Mahieux R.

J Virol. 2008 Jul;82(13):6747-52. doi: 10.1128/JVI.00247-08. Epub 2008 Apr 16.

12.

TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb.

Gegonne A, Weissman JD, Lu H, Zhou M, Dasgupta A, Ribble R, Brady JN, Singer DS.

Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5367-72. doi: 10.1073/pnas.0801637105. Epub 2008 Apr 7.

13.
14.

PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1-transformed cells.

Jeong SJ, Dasgupta A, Jung KJ, Um JH, Burke A, Park HU, Brady JN.

Virology. 2008 Jan 20;370(2):264-72. Epub 2007 Oct 10.

15.

Modulation of the Brd4/P-TEFb interaction by the human T-lymphotropic virus type 1 tax protein.

Cho WK, Zhou M, Jang MK, Huang K, Jeong SJ, Ozato K, Brady JN.

J Virol. 2007 Oct;81(20):11179-86. Epub 2007 Aug 8.

16.

Exenatide blocks JAK1-STAT1 in pancreatic beta cells.

Couto FM, Minn AH, Pise-Masison CA, Radonovich M, Brady JN, Hanson M, Fernandez LA, Wang P, Kendziorski C, Shalev A.

Metabolism. 2007 Jul;56(7):915-8.

PMID:
17570252
18.

Tax interacts with P-TEFb in a novel manner to stimulate human T-lymphotropic virus type 1 transcription.

Zhou M, Lu H, Park H, Wilson-Chiru J, Linton R, Brady JN.

J Virol. 2006 May;80(10):4781-91.

19.

The tax protein from the primate T-cell lymphotropic virus type 3 is expressed in vivo and is functionally related to HTLV-1 Tax rather than HTLV-2 Tax.

Chevalier SA, Meertens L, Pise-Masison C, Calattini S, Park H, Alhaj AA, Zhou M, Gessain A, Kashanchi F, Brady JN, Mahieux R.

Oncogene. 2006 Jul 27;25(32):4470-82. Epub 2006 Mar 13.

PMID:
16532031
20.

Genomic identification of potential risk factors during acetaminophen-induced liver disease in susceptible and resistant strains of mice.

Welch KD, Reilly TP, Bourdi M, Hays T, Pise-Masison CA, Radonovich MF, Brady JN, Dix DJ, Pohl LR.

Chem Res Toxicol. 2006 Feb;19(2):223-33.

PMID:
16485898
21.

TAF7: a possible transcription initiation check-point regulator.

Gegonne A, Weissman JD, Zhou M, Brady JN, Singer DS.

Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):602-7. Epub 2006 Jan 9.

22.

Characterization and isolation of stem cell-enriched human hair follicle bulge cells.

Ohyama M, Terunuma A, Tock CL, Radonovich MF, Pise-Masison CA, Hopping SB, Brady JN, Udey MC, Vogel JC.

J Clin Invest. 2006 Jan;116(1):249-60.

23.

Human T-cell leukemia virus type 1 Tax attenuates gamma-irradiation-induced apoptosis through physical interaction with Chk2.

Park HU, Jeong SJ, Jeong JH, Chung JH, Brady JN.

Oncogene. 2006 Jan 19;25(3):438-47.

PMID:
16158050
24.

Transcriptional and post-transcriptional gene regulation of HTLV-1.

Kashanchi F, Brady JN.

Oncogene. 2005 Sep 5;24(39):5938-51. Review.

PMID:
16155601
25.

Gene expression profiling in INS-1 cells overexpressing thioredoxin-interacting protein.

Minn AH, Pise-Masison CA, Radonovich M, Brady JN, Wang P, Kendziorski C, Shalev A.

Biochem Biophys Res Commun. 2005 Oct 28;336(3):770-8.

PMID:
16143294
26.

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription.

Jang MK, Mochizuki K, Zhou M, Jeong HS, Brady JN, Ozato K.

Mol Cell. 2005 Aug 19;19(4):523-34.

27.

Human T cell leukemia virus type 1: the role of Tax in leukemogenesis.

Pise-Masison CA, Jeong SJ, Brady JN.

Arch Immunol Ther Exp (Warsz). 2005 Jul-Aug;53(4):283-96. Review.

PMID:
16088313
28.

Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells.

Jeong SJ, Pise-Masison CA, Radonovich MF, Park HU, Brady JN.

Oncogene. 2005 Oct 6;24(44):6719-28.

PMID:
16007163
29.

Global analysis of IL-2 target genes: identification of chromosomal clusters of expressed genes.

Kovanen PE, Young L, Al-Shami A, Rovella V, Pise-Masison CA, Radonovich MF, Powell J, Fu J, Brady JN, Munson PJ, Leonard WJ.

Int Immunol. 2005 Aug;17(8):1009-21. Epub 2005 Jun 24.

PMID:
15980098
30.

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

Zeng R, Spolski R, Finkelstein SE, Oh S, Kovanen PE, Hinrichs CS, Pise-Masison CA, Radonovich MF, Brady JN, Restifo NP, Berzofsky JA, Leonard WJ.

J Exp Med. 2005 Jan 3;201(1):139-48.

31.

A novel NF-kappaB pathway involving IKKbeta and p65/RelA Ser-536 phosphorylation results in p53 Inhibition in the absence of NF-kappaB transcriptional activity.

Jeong SJ, Pise-Masison CA, Radonovich MF, Park HU, Brady JN.

J Biol Chem. 2005 Mar 18;280(11):10326-32. Epub 2004 Dec 20.

32.

Setting the stage for transformation: HTLV-1 Tax inhibition of p53 function.

Pise-Masison CA, Brady JN.

Front Biosci. 2005 Jan 1;10:919-30. Print 2005 Jan 1. Review.

PMID:
15569630
33.

Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription.

Zhou M, Deng L, Lacoste V, Park HU, Pumfery A, Kashanchi F, Brady JN, Kumar A.

J Virol. 2004 Dec;78(24):13522-33.

34.

Tax relieves transcriptional repression by promoting histone deacetylase 1 release from the human T-cell leukemia virus type 1 long terminal repeat.

Lu H, Pise-Masison CA, Linton R, Park HU, Schiltz RL, Sartorelli V, Brady JN.

J Virol. 2004 Jul;78(13):6735-43.

35.

HTLV-I Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity.

Jeong SJ, Radonovich M, Brady JN, Pise-Masison CA.

Blood. 2004 Sep 1;104(5):1490-7. Epub 2004 May 20. Erratum in: Blood. 2007 Jan 15;109(2):411.

PMID:
15155458
36.

Human T-cell leukemia virus type 1 Tax interacts with Chk1 and attenuates DNA-damage induced G2 arrest mediated by Chk1.

Park HU, Jeong JH, Chung JH, Brady JN.

Oncogene. 2004 Jun 24;23(29):4966-74.

PMID:
15107832
37.

Phosphorylation of p53 at serine 37 is important for transcriptional activity and regulation in response to DNA damage.

Dohoney KM, Guillerm C, Whiteford C, Elbi C, Lambert PF, Hager GL, Brady JN.

Oncogene. 2004 Jan 8;23(1):49-57.

PMID:
14712210
38.

The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA.

Zhou M, Deng L, Kashanchi F, Brady JN, Shatkin AJ, Kumar A.

Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12666-71. Epub 2003 Oct 20.

39.

P53 facilitates degradation of human T-cell leukaemia virus type I Tax-binding protein through a proteasome-dependent pathway.

Chowdhury IH, Radonovich M, Mahieux R, Pise-Masison C, Muralidhar S, Brady JN.

J Gen Virol. 2003 Apr;84(Pt 4):897-906.

PMID:
12655090
40.

Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice.

Ju C, Reilly TP, Bourdi M, Radonovich MF, Brady JN, George JW, Pohl LR.

Chem Res Toxicol. 2002 Dec;15(12):1504-13.

PMID:
12482232
41.

IL-2 negatively regulates IL-7 receptor alpha chain expression in activated T lymphocytes.

Xue HH, Kovanen PE, Pise-Masison CA, Berg M, Radovich MF, Brady JN, Leonard WJ.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13759-64. Epub 2002 Sep 27.

42.

Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway.

Shalev A, Pise-Masison CA, Radonovich M, Hoffmann SC, Hirshberg B, Brady JN, Harlan DM.

Endocrinology. 2002 Sep;143(9):3695-8.

PMID:
12193586
43.
44.

Transcription profile of cells infected with human T-cell leukemia virus type I compared with activated lymphocytes.

Pise-Masison CA, Radonovich M, Mahieux R, Chatterjee P, Whiteford C, Duvall J, Guillerm C, Gessain A, Brady JN.

Cancer Res. 2002 Jun 15;62(12):3562-71.

45.

Acetylation of nucleosomal histones by p300 facilitates transcription from tax-responsive human T-cell leukemia virus type 1 chromatin template.

Lu H, Pise-Masison CA, Fletcher TM, Schiltz RL, Nagaich AK, Radonovich M, Hager G, Cole PA, Brady JN.

Mol Cell Biol. 2002 Jul;22(13):4450-62.

46.

A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat.

Bharucha DC, Zhou M, Nekhai S, Brady JN, Shukla RR, Kumar A.

Virology. 2002 Apr 25;296(1):6-16.

47.

A protective role for cyclooxygenase-2 in drug-induced liver injury in mice.

Reilly TP, Brady JN, Marchick MR, Bourdi M, George JW, Radonovich MF, Pise-Masison CA, Pohl LR.

Chem Res Toxicol. 2001 Dec;14(12):1620-8.

PMID:
11743745
48.

Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1- and type 2-infected cells by a caspase-3-dependent mechanism involving Bcl-2 cleavage.

Mahieux R, Pise-Masison C, Gessain A, Brady JN, Olivier R, Perret E, Misteli T, Nicot C.

Blood. 2001 Dec 15;98(13):3762-9.

PMID:
11739184
49.

TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription.

Zhou M, Nekhai S, Bharucha DC, Kumar A, Ge H, Price DH, Egly JM, Brady JN.

J Biol Chem. 2001 Nov 30;276(48):44633-40. Epub 2001 Sep 25.

50.

Saccharomyces cerevisiae protein Pci8p and human protein eIF3e/Int-6 interact with the eIF3 core complex by binding to cognate eIF3b subunits.

Shalev A, Valásek L, Pise-Masison CA, Radonovich M, Phan L, Clayton J, He H, Brady JN, Hinnebusch AG, Asano K.

J Biol Chem. 2001 Sep 14;276(37):34948-57. Epub 2001 Jul 16.

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