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Items: 1 to 50 of 146

1.

Biomineralization strongly modulates the formation of Proteus mirabilis and Pseudomonas aeruginosa dual-species biofilms.

Li X, Lu N, Brady HR, Packman AI.

FEMS Microbiol Ecol. 2016 Oct 2. pii: fiw189. [Epub ahead of print]

PMID:
27697892
2.

Ureolytic Biomineralization Reduces Proteus mirabilis Biofilm Susceptibility to Ciprofloxacin.

Li X, Lu N, Brady HR, Packman AI.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):2993-3000. doi: 10.1128/AAC.00203-16. Print 2016 May.

3.

Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies.

Gallego-Delgado J, Connolly SB, Lázaro A, Sadlier D, Kieran NE, Sugrue DD, Doran P, Brady HR, Osende J, Egido J.

Hypertens Res. 2009 May;32(5):347-57. doi: 10.1038/hr.2009.27. Epub 2009 Mar 27.

PMID:
19325563
4.

IHG-1 amplifies TGF-beta1 signaling and is increased in renal fibrosis.

Murphy M, Docherty NG, Griffin B, Howlin J, McArdle E, McMahon R, Schmid H, Kretzler M, Droguett A, Mezzano S, Brady HR, Furlong F, Godson C, Martin F.

J Am Soc Nephrol. 2008 Sep;19(9):1672-80. doi: 10.1681/ASN.2007101080. Epub 2008 May 28.

5.

Association of VEGF-1499C-->T polymorphism with diabetic nephropathy in type 1 diabetes mellitus.

McKnight AJ, Maxwell AP, Patterson CC, Brady HR, Savage DA.

J Diabetes Complications. 2007 Jul-Aug;21(4):242-5.

PMID:
17616354
6.

Common polymorphisms of the PAI1 gene do not play a major role in the development of diabetic nephropathy in Type 1 diabetes.

Martin RJ, Savage DA, Patterson CC, Brady HR, Maxwell AP.

Diabet Med. 2007 Mar;24(3):259-65.

PMID:
17263760
7.

Association between haptoglobin gene variants and diabetic nephropathy: haptoglobin polymorphism in nephropathy susceptibility.

Conway BR, Savage DA, Brady HR, Maxwell AP.

Nephron Exp Nephrol. 2007;105(3):e75-9. Epub 2007 Jan 12.

PMID:
17220636
8.

ETV4 and Myeov knockdown impairs colon cancer cell line proliferation and invasion.

Moss AC, Lawlor G, Murray D, Tighe D, Madden SF, Mulligan AM, Keane CO, Brady HR, Doran PP, MacMathuna P.

Biochem Biophys Res Commun. 2006 Jun 23;345(1):216-21. Epub 2006 Apr 27.

PMID:
16678123
9.

Resequencing of the characterised CTGF gene to identify novel or known variants, and analysis of their association with diabetic nephropathy.

McKnight AJ, Savage DA, Patterson CC, Brady HR, Maxwell AP.

J Hum Genet. 2006;51(4):383-6. Epub 2006 Feb 24.

PMID:
16501850
10.

A genome-wide DNA microsatellite association screen to identify chromosomal regions harboring candidate genes in diabetic nephropathy.

McKnight AJ, Maxwell AP, Sawcer S, Compston A, Setakis E, Patterson CC, Brady HR, Savage DA.

J Am Soc Nephrol. 2006 Mar;17(3):831-6. Epub 2006 Feb 8.

11.

Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis.

Sadlier DM, Ouyang X, McMahon B, Mu W, Ohashi R, Rodgers K, Murray D, Nakagawa T, Godson C, Doran P, Brady HR, Johnson RJ.

Kidney Int. 2005 Dec;68(6):2542-61.

12.

Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy.

Dolan V, Murphy M, Sadlier D, Lappin D, Doran P, Godson C, Martin F, O'Meara Y, Schmid H, Henger A, Kretzler M, Droguett A, Mezzano S, Brady HR.

Am J Kidney Dis. 2005 Jun;45(6):1034-9.

PMID:
15957132
13.

Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor.

Leonard MO, Godson C, Brady HR, Taylor CT.

J Immunol. 2005 Feb 15;174(4):2250-7.

14.

Connective tissue growth factor [CTGF]/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization.

Crean JK, Furlong F, Finlay D, Mitchell D, Murphy M, Conway B, Brady HR, Godson C, Martin F.

FASEB J. 2004 Oct;18(13):1541-3. Epub 2004 Aug 19.

PMID:
15319369
15.

Role of alpha-adducin DNA polymorphisms in the genetic predisposition to diabetic nephropathy.

Conway BR, Martin R, McKnight AJ, Savage DA, Brady HR, Maxwell AP.

Nephrol Dial Transplant. 2004 Aug;19(8):2019-24. Epub 2004 Jun 8.

PMID:
15187197
16.

Association between variation in the actin-binding gene caldesmon and diabetic nephropathy in type 1 diabetes.

Conway BR, Maxwell AP, Savage DA, Patterson CC, Doran PP, Murphy M, Brady HR, Fogarty DG.

Diabetes. 2004 Apr;53(4):1162-5.

17.

Sequential extracellular matrix-focused and baited-global cluster analysis of serial transcriptomic profiles identifies candidate modulators of renal tubulointerstitial fibrosis in murine adriamycin-induced nephropathy.

Sadlier DM, Connolly SB, Kieran NE, Roxburgh S, Brazil DP, Kairaitis L, Wang Y, Harris DC, Doran P, Brady HR.

J Biol Chem. 2004 Jul 9;279(28):29670-80. Epub 2004 Mar 18.

18.

Lipoxins inhibit Akt/PKB activation and cell cycle progression in human mesangial cells.

Mitchell D, Rodgers K, Hanly J, McMahon B, Brady HR, Martin F, Godson C.

Am J Pathol. 2004 Mar;164(3):937-46.

19.

Posture-related tachycardia in older patients with hyponatremia.

Jones D, Biswas SK, Power DA, Cannon S, Brady HR, Grimes H, Mulkerrin EC.

Arch Gerontol Geriatr. 2002 Mar-Apr;34(2):145-54.

PMID:
14764318
20.

Mechanical deformation induced apoptosis in human proximal renal tubular epithelial cells is caspase dependent.

Power RE, Doyle BT, Higgins D, Brady HR, Fitzpatrick JM, Watson RW.

J Urol. 2004 Jan;171(1):457-61.

PMID:
14665955
21.

DNA oligonucleotide microarray technology identifies fisp-12 among other potential fibrogenic genes following murine unilateral ureteral obstruction (UUO): modulation during epithelial-mesenchymal transition.

Higgins DF, Lappin DW, Kieran NE, Anders HJ, Watson RW, Strutz F, Schlondorff D, Haase VH, Fitzpatrick JM, Godson C, Brady HR.

Kidney Int. 2003 Dec;64(6):2079-91.

22.

Identification of Naf1/ABIN-1 among TNF-alpha-induced expressed genes in human synoviocytes using oligonucleotide microarrays.

Gallagher J, Howlin J, McCarthy C, Murphy EP, Bresnihan B, FitzGerald O, Godson C, Brady HR, Martin F.

FEBS Lett. 2003 Sep 11;551(1-3):8-12.

23.

Digital extractor: analysis of digital differential display output.

Madden SF, O'Donovan B, Furney SJ, Brady HR, Silvestre G, Doran PP.

Bioinformatics. 2003 Aug 12;19(12):1594-5.

PMID:
12912848
24.

The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia.

Leonard MO, Cottell DC, Godson C, Brady HR, Taylor CT.

J Biol Chem. 2003 Oct 10;278(41):40296-304. Epub 2003 Jul 28.

25.

Gremlin - a putative pathogenic player in progressive renal disease.

Dolan V, Murphy M, Alarcon P, Brady HR, Hensey C.

Expert Opin Ther Targets. 2003 Aug;7(4):523-6. Review.

PMID:
12885271
26.

Transcriptome profiling and the pathogenesis of diabetic complications.

Connolly SB, Sadlier D, Kieran NE, Doran P, Brady HR.

J Am Soc Nephrol. 2003 Aug;14(8 Suppl 3):S279-83. Review.

27.

Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog.

Kieran NE, Doran PP, Connolly SB, Greenan MC, Higgins DF, Leonard M, Godson C, Taylor CT, Henger A, Kretzler M, Burne MJ, Rabb H, Brady HR.

Kidney Int. 2003 Aug;64(2):480-92.

28.

Lipoxins: pro-resolution lipid mediators in intestinal inflammation.

Goh J, Godson C, Brady HR, Macmathuna P.

Gastroenterology. 2003 Apr;124(4):1043-54. Review.

PMID:
12671901
29.

Biphasic regulation of leukocyte trafficking by lipoxins.

Stenson C, Mitchell S, Lappin D, Brady HR, Godson C.

Adv Exp Med Biol. 2002;507:543-9. Review. No abstract available.

PMID:
12664638
30.

Diabetic nephropathy: renal development gone awry?

Dolan V, Hensey C, Brady HR.

Pediatr Nephrol. 2003 Feb;18(2):75-84. Epub 2002 Nov 22. Review.

PMID:
12579392
31.

Connective tissue growth factor: an attractive therapeutic target in fibrotic renal disease.

Crean JK, Lappin D, Godson C, Brady HR.

Expert Opin Ther Targets. 2001 Aug;5(4):519-530.

PMID:
12540264
32.

The Xenopus pronephros as a model system for the study of kidney development and pathophysiology.

Hensey C, Dolan V, Brady HR.

Nephrol Dial Transplant. 2002;17 Suppl 9:73-4. Review.

PMID:
12386296
33.

Gremlin: an example of the re-emergence of developmental programmes in diabetic nephropathy.

Lappin DW, McMahon R, Murphy M, Brady HR.

Nephrol Dial Transplant. 2002;17 Suppl 9:65-7. Review.

PMID:
12386293
34.

Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo.

Mitchell S, Thomas G, Harvey K, Cottell D, Reville K, Berlasconi G, Petasis NA, Erwig L, Rees AJ, Savill J, Brady HR, Godson C.

J Am Soc Nephrol. 2002 Oct;13(10):2497-507.

35.

Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation.

McMahon B, Mitchell D, Shattock R, Martin F, Brady HR, Godson C.

FASEB J. 2002 Nov;16(13):1817-9. Epub 2002 Sep 5.

PMID:
12223454
36.
37.

Gremlins: is this what renal fibrogenesis has come to?

Murphy M, McMahon R, Lappin DW, Brady HR.

Exp Nephrol. 2002;10(4):241-4. Review. Erratum in: Exp Nephrol. 2003;93(2):e86.

PMID:
12097827
38.

Cytoprotective effects of nitrates in a cellular model of hydronephrosis.

Hegarty NJ, Watson RW, Young LS, O'Neill AJ, Brady HR, Fitzpatrick JM.

Kidney Int. 2002 Jul;62(1):70-7.

39.

Lipoxins induce actin reorganization in monocytes and macrophages but not in neutrophils: differential involvement of rho GTPases.

Maderna P, Cottell DC, Berlasconi G, Petasis NA, Brady HR, Godson C.

Am J Pathol. 2002 Jun;160(6):2275-83.

40.

15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure.

Leonard MO, Hannan K, Burne MJ, Lappin DW, Doran P, Coleman P, Stenson C, Taylor CT, Daniels F, Godson C, Petasis NA, Rabb H, Brady HR.

J Am Soc Nephrol. 2002 Jun;13(6):1657-62.

41.

Gene responses to hyperglycaemia.

Lappin DW, Doran P, Godson C, Brady HR.

Exp Nephrol. 2002;10(2):120-9. Review.

PMID:
11937759
42.

High glucose-altered gene expression in mesangial cells. Actin-regulatory protein gene expression is triggered by oxidative stress and cytoskeletal disassembly.

Clarkson MR, Murphy M, Gupta S, Lambe T, Mackenzie HS, Godson C, Martin F, Brady HR.

J Biol Chem. 2002 Mar 22;277(12):9707-12. Epub 2002 Jan 9. Erratum in: J Biol Chem 2002 Jun 21;277(25):23100-2.

43.

Priming prostate carcinoma cells for increased apoptosis is associated with up-regulation of the caspases.

Coffey RN, Watson RW, Hegarty PK, Watson CL, Wolohan L, Brady HR, O'Keane C, Fitzpatrick JM.

Cancer. 2001 Nov 1;92(9):2297-308.

PMID:
11745284
44.
45.

Lipoxins: revelations on resolution.

McMahon B, Mitchell S, Brady HR, Godson C.

Trends Pharmacol Sci. 2001 Aug;22(8):391-5. Review.

PMID:
11478982
46.

Lipoxins: novel anti-inflammatory therapeutics?

Godson C, Brady HR.

Curr Opin Investig Drugs. 2000 Nov;1(3):380-5. Review.

PMID:
11249723
47.

Light from DARCness.

Lappin DW, Brady HR.

Kidney Int. 2000 Oct;58(4):1816-7. No abstract available.

48.

Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosis.

Gupta S, Clarkson MR, Duggan J, Brady HR.

Kidney Int. 2000 Oct;58(4):1389-99. Review.

49.

Influence of lipoxin A(4) and other lipoxygenase-derived eicosanoids on tissue factor expression.

Maderna P, Godson C, Hannify G, Murphy M, Brady HR.

Am J Physiol Cell Physiol. 2000 Oct;279(4):C945-53.

50.

Gremlins, glomeruli and diabetic nephropathy.

Lappin DW, Hensey C, McMahon R, Godson C, Brady HR.

Curr Opin Nephrol Hypertens. 2000 Sep;9(5):469-72. Review.

PMID:
10990363

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