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Items: 1 to 50 of 188

1.

Will liquid biopsies improve outcomes for patients with small-cell lung cancer?

Blackhall F, Frese KK, Simpson K, Kilgour E, Brady G, Dive C.

Lancet Oncol. 2018 Sep;19(9):e470-e481. doi: 10.1016/S1470-2045(18)30455-8. Review.

PMID:
30191851
2.

Alkylating histone deacetylase inhibitors may have therapeutic value in experimental myeloperoxidase-ANCA vasculitis.

Dooley D, van Timmeren MM, O'Reilly VP, Brady G, O'Brien EC, Fazekas B, Hickey FB, Leacy E, Pusey CD, Tam FWK, Mehrling T, Heeringa P, Little MA.

Kidney Int. 2018 Nov;94(5):926-936. doi: 10.1016/j.kint.2018.05.028. Epub 2018 Aug 26.

PMID:
30158055
3.

Imaging in gastric anisakiasis.

Lalchandani UR, Weadock WJ, Brady GF, Wasnik AP.

Clin Imaging. 2018 Jul - Aug;50:286-288. doi: 10.1016/j.clinimag.2018.04.018. Epub 2018 May 1.

PMID:
29738996
4.

Potential association of LMNA-associated generalized lipodystrophy with juvenile dermatomyositis.

Sahinoz M, Khairi S, Cuttitta A, Brady GF, Rupani A, Meral R, Tayeh MK, Thomas P, Riebschleger M, Camelo-Piragua S, Innis JW, Bishr Omary M, Michele DE, Oral EA.

Clin Diabetes Endocrinol. 2018 Mar 27;4:6. doi: 10.1186/s40842-018-0058-3. eCollection 2018.

5.

Lamins and Lamin-Associated Proteins in Gastrointestinal Health and Disease.

Brady GF, Kwan R, Bragazzi Cunha J, Elenbaas JS, Omary MB.

Gastroenterology. 2018 May;154(6):1602-1619.e1. doi: 10.1053/j.gastro.2018.03.026. Epub 2018 Mar 13. Review.

PMID:
29549040
6.

Genetic mannose binding lectin deficiency is associated with airway microbiota diversity and reduced exacerbation frequency in COPD.

Dicker AJ, Crichton ML, Cassidy AJ, Brady G, Hapca A, Tavendale R, Einarsson GG, Furrie E, Elborn JS, Schembri S, Marshall SE, Palmer CNA, Chalmers JD.

Thorax. 2018 Jun;73(6):510-518. doi: 10.1136/thoraxjnl-2016-209931. Epub 2017 Nov 3.

7.

Structurally Analogous Degradable Version of Fluorene-Bipyridine Copolymer with Exceptional Selectivity for Large-Diameter Semiconducting Carbon Nanotubes.

Kanimozhi C, Brady GJ, Shea MJ, Huang P, Joo Y, Arnold MS, Gopalan P.

ACS Appl Mater Interfaces. 2017 Nov 22;9(46):40734-40742. doi: 10.1021/acsami.7b14115. Epub 2017 Nov 8.

PMID:
29067812
8.

Nanotube Alignment Mechanism in Floating Evaporative Self-Assembly.

Jinkins KR, Chan J, Brady GJ, Gronski KK, Gopalan P, Evensen HT, Berson A, Arnold MS.

Langmuir. 2017 Nov 21;33(46):13407-13414. doi: 10.1021/acs.langmuir.7b02827. Epub 2017 Nov 7.

PMID:
29058446
9.

Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective Steatohepatitis.

Kwan R, Brady GF, Brzozowski M, Weerasinghe SV, Martin H, Park MJ, Brunt MJ, Menon RK, Tong X, Yin L, Stewart CL, Omary MB.

Cell Mol Gastroenterol Hepatol. 2017 Jul 6;4(3):365-383. doi: 10.1016/j.jcmgh.2017.06.005. eCollection 2017 Nov.

10.

Challenges and unanswered questions for the next decade of circulating tumour cell research in lung cancer.

Mohan S, Chemi F, Brady G.

Transl Lung Cancer Res. 2017 Aug;6(4):454-472. doi: 10.21037/tlcr.2017.06.04. Review.

11.

Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.

Brady GF, Kwan R, Ulintz PJ, Nguyen P, Bassirian S, Basrur V, Nesvizhskii AI, Loomba R, Omary MB.

Hepatology. 2018 May;67(5):1710-1725. doi: 10.1002/hep.29522. Epub 2018 Mar 24.

PMID:
28902428
12.

An investigation of the prevalence of swallowing difficulties and impact on quality of life in patients with advanced lung cancer.

Brady GC, Roe JWG, O' Brien M, Boaz A, Shaw C.

Support Care Cancer. 2018 Feb;26(2):515-519. doi: 10.1007/s00520-017-3858-6. Epub 2017 Sep 2.

PMID:
28866829
13.

Polymer-Free Electronic-Grade Aligned Semiconducting Carbon Nanotube Array.

Joo Y, Brady GJ, Kanimozhi C, Ko J, Shea MJ, Strand MT, Arnold MS, Gopalan P.

ACS Appl Mater Interfaces. 2017 Aug 30;9(34):28859-28867. doi: 10.1021/acsami.7b06850. Epub 2017 Aug 16.

PMID:
28758721
14.

Molecular analysis of single circulating tumour cells following long-term storage of clinical samples.

Mesquita B, Rothwell DG, Burt DJ, Chemi F, Fernandez-Gutierrez F, Slane-Tan D, Antonello J, Carter M, Carter L, Parry M, Franklin L, Marais R, Blackhall F, Dive C, Brady G.

Mol Oncol. 2017 Dec;11(12):1687-1697. doi: 10.1002/1878-0261.12113. Epub 2017 Oct 24.

15.

Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity.

Zhang D, Tong X, VanDommelen K, Gupta N, Stamper K, Brady GF, Meng Z, Lin J, Rui L, Omary MB, Yin L.

J Clin Invest. 2017 Jun 30;127(7):2855-2867. doi: 10.1172/JCI89934. Epub 2017 Jun 19.

16.

Neutrophil extracellular traps are associated with disease severity and microbiota diversity in patients with chronic obstructive pulmonary disease.

Dicker AJ, Crichton ML, Pumphrey EG, Cassidy AJ, Suarez-Cuartin G, Sibila O, Furrie E, Fong CJ, Ibrahim W, Brady G, Einarsson GG, Elborn JS, Schembri S, Marshall SE, Palmer CNA, Chalmers JD.

J Allergy Clin Immunol. 2018 Jan;141(1):117-127. doi: 10.1016/j.jaci.2017.04.022. Epub 2017 May 13.

17.

Molluscum Contagiosum Virus Protein MC005 Inhibits NF-κB Activation by Targeting NEMO-Regulated IκB Kinase Activation.

Brady G, Haas DA, Farrell PJ, Pichlmair A, Bowie AG.

J Virol. 2017 Jul 12;91(15). pii: e00545-17. doi: 10.1128/JVI.00545-17. Print 2017 Aug 1.

18.

twoddpcr: an R/Bioconductor package and Shiny app for Droplet Digital PCR analysis.

Chiu A, Ayub M, Dive C, Brady G, Miller CJ.

Bioinformatics. 2017 Sep 1;33(17):2743-2745. doi: 10.1093/bioinformatics/btx308.

19.

Next-Generation Sequencing Analysis and Algorithms for PDX and CDX Models.

Khandelwal G, Girotti MR, Smowton C, Taylor S, Wirth C, Dynowski M, Frese KK, Brady G, Dive C, Marais R, Miller C.

Mol Cancer Res. 2017 Aug;15(8):1012-1016. doi: 10.1158/1541-7786.MCR-16-0431. Epub 2017 Apr 25.

20.

SnapShot: Circulating Tumor Cells.

Dive C, Brady G.

Cell. 2017 Mar 23;169(1):176. doi: 10.1016/j.cell.2017.03.017. No abstract available.

21.

Spectrum of disease associated with partial lipodystrophy: lessons from a trial cohort.

Ajluni N, Meral R, Neidert AH, Brady GF, Buras E, McKenna B, DiPaola F, Chenevert TL, Horowitz JF, Buggs-Saxton C, Rupani AR, Thomas PE, Tayeh MK, Innis JW, Omary MB, Conjeevaram H, Oral EA.

Clin Endocrinol (Oxf). 2017 May;86(5):698-707. doi: 10.1111/cen.13311. Epub 2017 Mar 27.

22.

SnapShot: Circulating Tumor Cells.

Dive C, Brady G.

Cell. 2017 Feb 9;168(4):742-742.e1. doi: 10.1016/j.cell.2017.01.026. Erratum in: Cell. 2017 Mar 23;169(1):176.

23.

General Anesthesia During Endovascular Stroke Therapy Does Not Negatively Impact Outcome.

Wang A, Stellfox M, Moy F, Abramowicz AE, Lehrer R, Epstein R, Eiden N, Aquilina A, Pednekar N, Brady G, Wecksell M, Cooley J, Santarelli J, Stiefel MF.

World Neurosurg. 2017 Mar;99:638-643. doi: 10.1016/j.wneu.2016.12.064. Epub 2016 Dec 23.

PMID:
28017749
24.

Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1.

Brady G, Boggan L, Bowie A, O'Neill LA.

J Biol Chem. 2016 Nov 25;291(48):25278. No abstract available.

25.

Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer.

Carter L, Rothwell DG, Mesquita B, Smowton C, Leong HS, Fernandez-Gutierrez F, Li Y, Burt DJ, Antonello J, Morrow CJ, Hodgkinson CL, Morris K, Priest L, Carter M, Miller C, Hughes A, Blackhall F, Dive C, Brady G.

Nat Med. 2017 Jan;23(1):114-119. doi: 10.1038/nm.4239. Epub 2016 Nov 21.

PMID:
27869802
26.

Vasculogenic mimicry in small cell lung cancer.

Williamson SC, Metcalf RL, Trapani F, Mohan S, Antonello J, Abbott B, Leong HS, Chester CP, Simms N, Polanski R, Nonaka D, Priest L, Fusi A, Carlsson F, Carlsson A, Hendrix MJ, Seftor RE, Seftor EA, Rothwell DG, Hughes A, Hicks J, Miller C, Kuhn P, Brady G, Simpson KL, Blackhall FH, Dive C.

Nat Commun. 2016 Nov 9;7:13322. doi: 10.1038/ncomms13322.

27.

Quasi-ballistic carbon nanotube array transistors with current density exceeding Si and GaAs.

Brady GJ, Way AJ, Safron NS, Evensen HT, Gopalan P, Arnold MS.

Sci Adv. 2016 Sep 2;2(9):e1601240. doi: 10.1126/sciadv.1601240. eCollection 2016 Sep.

28.

Distinct subclonal tumour responses to therapy revealed by circulating cell-free DNA.

Gremel G, Lee RJ, Girotti MR, Mandal AK, Valpione S, Garner G, Ayub M, Wood S, Rothwell DG, Fusi A, Wallace A, Brady G, Dive C, Dhomen N, Lorigan P, Marais R.

Ann Oncol. 2016 Oct;27(10):1959-65. doi: 10.1093/annonc/mdw278. Epub 2016 Aug 8.

29.

Radio Frequency Transistors Using Aligned Semiconducting Carbon Nanotubes with Current-Gain Cutoff Frequency and Maximum Oscillation Frequency Simultaneously Greater than 70 GHz.

Cao Y, Brady GJ, Gui H, Rutherglen C, Arnold MS, Zhou C.

ACS Nano. 2016 Jul 26;10(7):6782-90. doi: 10.1021/acsnano.6b02395. Epub 2016 Jun 21.

PMID:
27327074
30.

Research into the prevention and rehabilitation of dysphagia in head and neck cancer: a UK perspective.

Patterson JM, Brady GC, Roe JW.

Curr Opin Otolaryngol Head Neck Surg. 2016 Jun;24(3):208-14. doi: 10.1097/MOO.0000000000000260. Review.

PMID:
27054623
31.

Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study.

Morrow CJ, Trapani F, Metcalf RL, Bertolini G, Hodgkinson CL, Khandelwal G, Kelly P, Galvin M, Carter L, Simpson KL, Williamson S, Wirth C, Simms N, Frankliln L, Frese KK, Rothwell DG, Nonaka D, Miller CJ, Brady G, Blackhall FH, Dive C.

Ann Oncol. 2016 Jun;27(6):1155-60. doi: 10.1093/annonc/mdw122. Epub 2016 Mar 24.

32.

Application of Sequencing, Liquid Biopsies, and Patient-Derived Xenografts for Personalized Medicine in Melanoma.

Girotti MR, Gremel G, Lee R, Galvani E, Rothwell D, Viros A, Mandal AK, Lim KH, Saturno G, Furney SJ, Baenke F, Pedersen M, Rogan J, Swan J, Smith M, Fusi A, Oudit D, Dhomen N, Brady G, Lorigan P, Dive C, Marais R.

Cancer Discov. 2016 Mar;6(3):286-99. doi: 10.1158/2159-8290.CD-15-1336. Epub 2015 Dec 29.

33.

Development of a circulating miRNA assay to monitor tumor burden: From mouse to man.

Greystoke A, Ayub M, Rothwell DG, Morris D, Burt D, Hodgkinson CL, Morrow CJ, Smith N, Aung K, Valle J, Carter L, Blackhall F, Dive C, Brady G.

Mol Oncol. 2016 Feb;10(2):282-91. doi: 10.1016/j.molonc.2015.10.004. Epub 2015 Oct 28.

34.

Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample.

Rothwell DG, Smith N, Morris D, Leong HS, Li Y, Hollebecque A, Ayub M, Carter L, Antonello J, Franklin L, Miller C, Blackhall F, Dive C, Brady G.

Mol Oncol. 2016 Apr;10(4):566-74. doi: 10.1016/j.molonc.2015.11.006. Epub 2015 Nov 19.

35.

Clinical evaluation of a novel microfluidic device for epitope-independent enrichment of circulating tumour cells in patients with small cell lung cancer.

Chudziak J, Burt DJ, Mohan S, Rothwell DG, Mesquita B, Antonello J, Dalby S, Ayub M, Priest L, Carter L, Krebs MG, Blackhall F, Dive C, Brady G.

Analyst. 2016 Jan 21;141(2):669-78. doi: 10.1039/c5an02156a.

PMID:
26605519
36.

Isolation of Pristine Electronics Grade Semiconducting Carbon Nanotubes by Switching the Rigidity of the Wrapping Polymer Backbone on Demand.

Joo Y, Brady GJ, Shea MJ, Oviedo MB, Kanimozhi C, Schmitt SK, Wong BM, Arnold MS, Gopalan P.

ACS Nano. 2015 Oct 27;9(10):10203-13. doi: 10.1021/acsnano.5b03835. Epub 2015 Sep 15.

PMID:
26348205
37.

Direct oriented growth of armchair graphene nanoribbons on germanium.

Jacobberger RM, Kiraly B, Fortin-Deschenes M, Levesque PL, McElhinny KM, Brady GJ, Rojas Delgado R, Singha Roy S, Mannix A, Lagally MG, Evans PG, Desjardins P, Martel R, Hersam MC, Guisinger NP, Arnold MS.

Nat Commun. 2015 Aug 10;6:8006. doi: 10.1038/ncomms9006.

38.

Spatially Estimating Disturbance of Harbor Seals (Phoca vitulina).

Jansen JK, Brady GM, Ver Hoef JM, Boveng PL.

PLoS One. 2015 Jul 1;10(7):e0129798. doi: 10.1371/journal.pone.0129798. eCollection 2015.

39.

Poxvirus Protein MC132 from Molluscum Contagiosum Virus Inhibits NF-B Activation by Targeting p65 for Degradation.

Brady G, Haas DA, Farrell PJ, Pichlmair A, Bowie AG.

J Virol. 2015 Aug;89(16):8406-15.

40.

Contemporary management of voice and swallowing disorders in patients with advanced lung cancer.

Brady GC, Carding PN, Bhosle J, Roe JW.

Curr Opin Otolaryngol Head Neck Surg. 2015 Jun;23(3):191-6. doi: 10.1097/MOO.0000000000000155. Review.

PMID:
25887976
41.

Connecting a sociology of childhood perspective with the study of child health, illness and wellbeing: introduction.

Brady G, Lowe P, Olin Lauritzen S.

Sociol Health Illn. 2015 Feb;37(2):173-83. doi: 10.1111/1467-9566.12260.

PMID:
25760921
42.

Evaluation and validation of a robust single cell RNA-amplification protocol through transcriptional profiling of enriched lung cancer initiating cells.

Rothwell DG, Li Y, Ayub M, Tate C, Newton G, Hey Y, Carter L, Faulkner S, Moro M, Pepper S, Miller C, Blackhall F, Bertolini G, Roz L, Dive C, Brady G.

BMC Genomics. 2014 Dec 17;15:1129. doi: 10.1186/1471-2164-15-1129.

43.

Polyfluorene-sorted, carbon nanotube array field-effect transistors with increased current density and high on/off ratio.

Brady GJ, Joo Y, Wu MY, Shea MJ, Gopalan P, Arnold MS.

ACS Nano. 2014 Nov 25;8(11):11614-21. doi: 10.1021/nn5048734. Epub 2014 Nov 13.

PMID:
25383880
44.

Innate immune activation of NFκB and its antagonism by poxviruses.

Brady G, Bowie AG.

Cytokine Growth Factor Rev. 2014 Oct;25(5):611-20. doi: 10.1016/j.cytogfr.2014.07.004. Epub 2014 Jul 11. Review.

PMID:
25081317
45.

Tracking genomic cancer evolution for precision medicine: the lung TRACERx study.

Jamal-Hanjani M, Hackshaw A, Ngai Y, Shaw J, Dive C, Quezada S, Middleton G, de Bruin E, Le Quesne J, Shafi S, Falzon M, Horswell S, Blackhall F, Khan I, Janes S, Nicolson M, Lawrence D, Forster M, Fennell D, Lee SM, Lester J, Kerr K, Muller S, Iles N, Smith S, Murugaesu N, Mitter R, Salm M, Stuart A, Matthews N, Adams H, Ahmad T, Attanoos R, Bennett J, Birkbak NJ, Booton R, Brady G, Buchan K, Capitano A, Chetty M, Cobbold M, Crosbie P, Davies H, Denison A, Djearman M, Goldman J, Haswell T, Joseph L, Kornaszewska M, Krebs M, Langman G, MacKenzie M, Millar J, Morgan B, Naidu B, Nonaka D, Peggs K, Pritchard C, Remmen H, Rowan A, Shah R, Smith E, Summers Y, Taylor M, Veeriah S, Waller D, Wilcox B, Wilcox M, Woolhouse I, McGranahan N, Swanton C.

PLoS Biol. 2014 Jul 8;12(7):e1001906. doi: 10.1371/journal.pbio.1001906. eCollection 2014 Jul.

46.

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer.

Hodgkinson CL, Morrow CJ, Li Y, Metcalf RL, Rothwell DG, Trapani F, Polanski R, Burt DJ, Simpson KL, Morris K, Pepper SD, Nonaka D, Greystoke A, Kelly P, Bola B, Krebs MG, Antonello J, Ayub M, Faulkner S, Priest L, Carter L, Tate C, Miller CJ, Blackhall F, Brady G, Dive C.

Nat Med. 2014 Aug;20(8):897-903. doi: 10.1038/nm.3600. Epub 2014 Jun 1.

PMID:
24880617
47.

Analytical validation of BRAF mutation testing from circulating free DNA using the amplification refractory mutation testing system.

Aung KL, Donald E, Ellison G, Bujac S, Fletcher L, Cantarini M, Brady G, Orr M, Clack G, Ranson M, Dive C, Hughes A.

J Mol Diagn. 2014 May;16(3):343-9. doi: 10.1016/j.jmoldx.2013.12.004. Epub 2014 Mar 12.

PMID:
24631158
48.

Dose-controlled, floating evaporative self-assembly and alignment of semiconducting carbon nanotubes from organic solvents.

Joo Y, Brady GJ, Arnold MS, Gopalan P.

Langmuir. 2014 Apr 1;30(12):3460-6. doi: 10.1021/la500162x. Epub 2014 Mar 18.

PMID:
24580418
49.

Molecular analysis of circulating tumour cells-biology and biomarkers.

Krebs MG, Metcalf RL, Carter L, Brady G, Blackhall FH, Dive C.

Nat Rev Clin Oncol. 2014 Mar;11(3):129-44. doi: 10.1038/nrclinonc.2013.253. Epub 2014 Jan 21. Review.

PMID:
24445517
50.

Assessment of esophageal dysfunction and symptoms during and after a standardized test meal: development and clinical validation of a new methodology utilizing high-resolution manometry.

Sweis R, Anggiansah A, Wong T, Brady G, Fox M.

Neurogastroenterol Motil. 2014 Feb;26(2):215-28. doi: 10.1111/nmo.12252. Epub 2013 Nov 18.

PMID:
24238326

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