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Items: 32

1.

Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial.

Biondi A, Gandemer V, De Lorenzo P, Cario G, Campbell M, Castor A, Pieters R, Baruchel A, Vora A, Leoni V, Stary J, Escherich G, Li CK, Cazzaniga G, Cavé H, Bradtke J, Conter V, Saha V, Schrappe M, Grazia Valsecchi M.

Lancet Haematol. 2018 Dec;5(12):e641-e652. doi: 10.1016/S2352-3026(18)30173-X.

PMID:
30501871
2.

Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor.

Biondi A, Cario G, De Lorenzo P, Castor A, Conter V, Leoni V, Gandemer V, Pieters R, Stary J, Escherich G, Campbell M, Attarbaschi A, Li CK, Vora A, Bradtke J, Saha V, Valsecchi MG, Schrappe M.

Haematologica. 2019 Jan;104(1):e13-e16. doi: 10.3324/haematol.2018.199422. Epub 2018 Sep 13. No abstract available.

3.

Genotype-outcome correlations in pediatric AML: the impact of a monosomal karyotype in trial AML-BFM 2004.

Rasche M, von Neuhoff C, Dworzak M, Bourquin JP, Bradtke J, Göhring G, Escherich G, Fleischhack G, Graf N, Gruhn B, Haas OA, Klingebiel T, Kremens B, Lehrnbecher T, von Stackelberg A, Tchinda J, Zemanova Z, Thiede C, von Neuhoff N, Zimmermann M, Creutzig U, Reinhardt D.

Leukemia. 2017 Dec;31(12):2807-2814. doi: 10.1038/leu.2017.121. Epub 2017 Apr 25.

4.

Changes in cytogenetics and molecular genetics in acute myeloid leukemia from childhood to adult age groups.

Creutzig U, Zimmermann M, Reinhardt D, Rasche M, von Neuhoff C, Alpermann T, Dworzak M, Perglerová K, Zemanova Z, Tchinda J, Bradtke J, Thiede C, Haferlach C.

Cancer. 2016 Dec 15;122(24):3821-3830. doi: 10.1002/cncr.30220. Epub 2016 Aug 16.

5.

Next-generation-sequencing of recurrent childhood high hyperdiploid acute lymphoblastic leukemia reveals mutations typically associated with high risk patients.

Chen C, Bartenhagen C, Gombert M, Okpanyi V, Binder V, Röttgers S, Bradtke J, Teigler-Schlegel A, Harbott J, Ginzel S, Thiele R, Husemann P, Krell PF, Borkhardt A, Dugas M, Hu J, Fischer U.

Leuk Res. 2015 Sep;39(9):990-1001. doi: 10.1016/j.leukres.2015.06.005. Epub 2015 Jun 14.

PMID:
26189108
6.

From initiation to eradication: the lifespan of an MLL-rearranged therapy-related paediatric AML.

Krumbholz M, Bradtke J, Stachel D, Peters O, Hero B, Holter W, Slany R, Metzler M.

Bone Marrow Transplant. 2015 Oct;50(10):1382-4. doi: 10.1038/bmt.2015.155. Epub 2015 Jul 6. No abstract available.

PMID:
26146805
7.

Sequential karyotyping in Burkitt lymphoma reveals a linear clonal evolution with increase in karyotype complexity and a high frequency of recurrent secondary aberrations.

Aukema SM, Theil L, Rohde M, Bauer B, Bradtke J, Burkhardt B, Bonn BR, Claviez A, Gattenlöhner S, Makarova O, Nagel I, Oschlies I, Pott C, Szczepanowski M, Traulsen A, Kluin PM, Klapper W, Siebert R, Murga Penas EM.

Br J Haematol. 2015 Sep;170(6):814-25. doi: 10.1111/bjh.13501. Epub 2015 Jun 24.

PMID:
26104998
8.

Minimal residual disease-based treatment is adequate for relapse-prone childhood acute lymphoblastic leukemia with an intrachromosomal amplification of chromosome 21: the experience of the ALL-BFM 2000 trial.

Attarbaschi A, Panzer-Grümayer R, Mann G, Möricke A, König M, Mecklenbräuker A, Teigler-Schlegel A, Bradtke J, Harbott J, Göhring G, Stanulla M, Schrappe M, Zimmermann M, Haas OA; Austrian and German ALL-BFM (Berlin-Frankfurt-Münster) Study Group.

Klin Padiatr. 2014 Nov;226(6-7):338-43. doi: 10.1055/s-0034-1387795. Epub 2014 Nov 28.

PMID:
25431866
9.

Response monitoring of infant acute myeloid leukemia treatment by quantification of the tumor specific MLL-FNBP1 fusion gene.

Krumbholz M, Jung R, Bradtke J, Reinhardt D, Stachel D, Metzler M.

Leuk Lymphoma. 2015 Mar;56(3):793-6. doi: 10.3109/10428194.2014.928933. Epub 2014 Jul 17. No abstract available.

PMID:
24884312
10.

DNA copy number alterations mark disease progression in paediatric chronic myeloid leukaemia.

van der Sligte NE, Krumbholz M, Pastorczak A, Scheijen B, Tauer JT, Nowasz C, Sonneveld E, de Bock GH, Meeuwsen-de Boer TG, van Reijmersdal S, Kuiper RP, Bradtke J, Metzler M, Suttorp M, de Bont ES, van Leeuwen FN.

Br J Haematol. 2014 Jul;166(2):250-3. doi: 10.1111/bjh.12850. Epub 2014 Mar 27. Erratum in: Br J Haematol. 2014 Nov;167(4):584.

PMID:
24673583
11.

PAX5 fusion genes in t(7;9)(q11.2;p13) leukemia: a case report and review of the literature.

Denk D, Bradtke J, König M, Strehl S.

Mol Cytogenet. 2014 Feb 7;7(1):13. doi: 10.1186/1755-8166-7-13.

12.

Next-generation-sequencing-based risk stratification and identification of new genes involved in structural and sequence variations in near haploid lymphoblastic leukemia.

Chen C, Bartenhagen C, Gombert M, Okpanyi V, Binder V, Röttgers S, Bradtke J, Teigler-Schlegel A, Harbott J, Ginzel S, Thiele R, Fischer U, Dugas M, Hu J, Borkhardt A.

Genes Chromosomes Cancer. 2013 Jun;52(6):564-79. doi: 10.1002/gcc.22054. Epub 2013 Mar 18.

PMID:
23508829
13.

MicroRNAs distinguish cytogenetic subgroups in pediatric AML and contribute to complex regulatory networks in AML-relevant pathways.

Daschkey S, Röttgers S, Giri A, Bradtke J, Teigler-Schlegel A, Meister G, Borkhardt A, Landgraf P.

PLoS One. 2013;8(2):e56334. doi: 10.1371/journal.pone.0056334. Epub 2013 Feb 13.

14.

Recurrent involvement of ring-type zinc finger genes in complex molecular rearrangements in childhood acute myelogeneous leukemia with translocation t(10;11)(p12;q23).

Ghosh S, Bartenhagen C, Okpanyi V, Gombert M, Binder V, Teigler-Schlegel A, Bradtke J, Röttgers S, Dugas M, Borkhardt A.

Leukemia. 2013 Aug;27(8):1745-8. doi: 10.1038/leu.2013.1. Epub 2013 Jan 9. No abstract available.

PMID:
23299548
15.

Quantification of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL) using amplicon-fusion-site polymerase chain reaction (AFS-PCR).

Weber A, Taube S, Zur Stadt U, Horstmann M, Krohn K, Bradtke J, Teigler-Schlegel A, Leiblein S, Christiansen H.

Exp Hematol Oncol. 2012 Nov 9;1(1):33. doi: 10.1186/2162-3619-1-33.

16.

Treatment outcome of CRLF2-rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the AIEOP-BFM and UK NCRI-CCLG study groups.

Attarbaschi A, Morak M, Cario G, Cazzaniga G, Ensor HM, te Kronnie T, Bradtke J, Mann G, Vendramini E, Palmi C, Schwab C, Russell LJ, Schrappe M, Conter V, Mitchell CD, Strehl S, Zimmermann M, Pötschger U, Harrison CJ, Stanulla M, Panzer-Grümayer R, Haas OA, Moorman AV; Associazione Italiana di Ematologia ed Oncologia Pediatrica (AIEOP)-Berlin-Frankfurt-Münster (BFM) Study Group and National Cancer Research Institute (NCRI)-Children's Cancer and Leukaemia (CCLG) Study Group.

Br J Haematol. 2012 Sep;158(6):772-7. doi: 10.1111/j.1365-2141.2012.09221.x. Epub 2012 Jul 23.

PMID:
22816614
17.

PAX5-AUTS2: a recurrent fusion gene in childhood B-cell precursor acute lymphoblastic leukemia.

Denk D, Nebral K, Bradtke J, Pass G, Möricke A, Attarbaschi A, Strehl S.

Leuk Res. 2012 Aug;36(8):e178-81. doi: 10.1016/j.leukres.2012.04.015. Epub 2012 May 12. Review.

18.

Abl-interactor 2 (ABI2): a novel MLL translocation partner in acute myeloid leukemia.

Coenen EA, Zwaan CM, Meyer C, Marschalek R, Creutzig U, Pieters R, Bradtke J, van den Heuvel-Eibrink MM.

Leuk Res. 2012 May;36(5):e113-5. doi: 10.1016/j.leukres.2012.01.005. Epub 2012 Feb 1. No abstract available.

PMID:
22304832
19.

Genomic imbalances are confined to non-proliferating cells in paediatric patients with acute myeloid leukaemia and a normal or incomplete karyotype.

Ballabio E, Regan R, Garimberti E, Harbott J, Bradtke J, Teigler-Schlegel A, Biondi A, Cazzaniga G, Giudici G, Wainscoat JS, Boultwood J, Bridger JM, Knight SJ, Tosi S.

PLoS One. 2011;6(6):e20607. doi: 10.1371/journal.pone.0020607. Epub 2011 Jun 9.

20.

PAX5-AUTS2 fusion resulting from t(7;9)(q11.2;p13.2) can now be classified as recurrent in B cell acute lymphoblastic leukemia.

Coyaud E, Struski S, Dastugue N, Brousset P, Broccardo C, Bradtke J.

Leuk Res. 2010 Dec;34(12):e323-5. doi: 10.1016/j.leukres.2010.07.035. Epub 2010 Aug 17. Review. No abstract available.

PMID:
20723977
21.

Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98.

von Neuhoff C, Reinhardt D, Sander A, Zimmermann M, Bradtke J, Betts DR, Zemanova Z, Stary J, Bourquin JP, Haas OA, Dworzak MN, Creutzig U.

J Clin Oncol. 2010 Jun 1;28(16):2682-9. doi: 10.1200/JCO.2009.25.6321. Epub 2010 May 3.

PMID:
20439630
22.

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study.

Conter V, Bartram CR, Valsecchi MG, Schrauder A, Panzer-Grümayer R, Möricke A, Aricò M, Zimmermann M, Mann G, De Rossi G, Stanulla M, Locatelli F, Basso G, Niggli F, Barisone E, Henze G, Ludwig WD, Haas OA, Cazzaniga G, Koehler R, Silvestri D, Bradtke J, Parasole R, Beier R, van Dongen JJ, Biondi A, Schrappe M.

Blood. 2010 Apr 22;115(16):3206-14. doi: 10.1182/blood-2009-10-248146. Epub 2010 Feb 12.

23.

Acute leukaemias of ambiguous lineage in children: characterization, prognosis and therapy recommendations.

Gerr H, Zimmermann M, Schrappe M, Dworzak M, Ludwig WD, Bradtke J, Moericke A, Schabath R, Creutzig U, Reinhardt D.

Br J Haematol. 2010 Apr;149(1):84-92. doi: 10.1111/j.1365-2141.2009.08058.x. Epub 2010 Jan 18.

PMID:
20085575
24.

Distribution of NPM1-ALK and X-ALK fusion transcripts in paediatric anaplastic large cell lymphoma: a molecular-histological correlation.

Damm-Welk C, Klapper W, Oschlies I, Gesk S, Röttgers S, Bradtke J, Siebert R, Reiter A, Woessmann W.

Br J Haematol. 2009 Aug;146(3):306-9. doi: 10.1111/j.1365-2141.2009.07754.x. Epub 2009 May 26.

PMID:
19545284
25.

CyDAS: a cytogenetic data analysis system.

Hiller B, Bradtke J, Balz H, Rieder H.

Bioinformatics. 2005 Apr 1;21(7):1282-3. Epub 2004 Nov 16.

PMID:
15546933
26.

Computer aided analysis of additional chromosome aberrations in Philadelphia chromosome positive acute lymphoblastic leukaemia using a simplified computer readable cytogenetic notation.

Bradtke J, Balz H, Fonatsch C, Heinze B, Jauch A, Mohr B, Schoch C, Rieder H.

BMC Bioinformatics. 2003 Jan 28;4:4. Epub 2003 Jan 28.

27.

Diurnal rhythm of melatonin action on sexual maturation of male rats.

Lang U, Rivest RW, Schlaepfer LV, Bradtke JC, Aubert ML, Sizonenko PC.

Neuroendocrinology. 1984 Apr;38(4):261-8.

PMID:
6328341
28.

Influence of exogenous melatonin on melatonin secretion and the neuroendocrine reproductive axis of intact male rats during sexual maturation.

Lang U, Aubert ML, Conne BS, Bradtke JC, Sizonenko PC.

Endocrinology. 1983 May;112(5):1578-84.

PMID:
6299701
29.

Long-term studies on immunoreactive human melatonin.

Arendt J, Wirz-Justice A, Bradtke J, Kornemark M.

Ann Clin Biochem. 1979 Nov;16(6):307-12.

PMID:
539790
31.

Annual rhythm of serum melatonin in man.

Arendt J, Wirz-Justice A, Bradtke J.

Neurosci Lett. 1978 Mar;7(4):327-30. No abstract available.

PMID:
19605134
32.

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