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Items: 37

1.

Relationship between inorganic ion distribution, resting membrane potential and the ΔG' of ATP hydrolysis: a new paradigm.

Veech RL, King MT, Pawlosky R, Bradshaw PC, Curtis W.

FASEB J. 2019 Nov 5:fj201901942R. doi: 10.1096/fj.201901942R. [Epub ahead of print]

PMID:
31690124
2.

Effects of a high protein diet and liver disease in an in silico model of human ammonia metabolism.

Griffin JWD, Bradshaw PC.

Theor Biol Med Model. 2019 Jul 31;16(1):11. doi: 10.1186/s12976-019-0109-1.

3.

Cytoplasmic and Mitochondrial NADPH-Coupled Redox Systems in the Regulation of Aging.

Bradshaw PC.

Nutrients. 2019 Feb 27;11(3). pii: E504. doi: 10.3390/nu11030504. Review.

4.

The "great" controlling nucleotide coenzymes.

Veech RL, Todd King M, Pawlosky R, Kashiwaya Y, Bradshaw PC, Curtis W.

IUBMB Life. 2019 May;71(5):565-579. doi: 10.1002/iub.1997. Epub 2019 Jan 9. Review.

PMID:
30624851
5.

The effects of AICAR and rapamycin on mitochondrial function in immortalized mitochondrial DNA mutator murine embryonic fibroblasts.

Delic V, Noble K, Zivkovic S, Phan TA, Reynes C, Zhang Y, Phillips O, Claybaker C, Ta Y, Dinh VB, Cruz J, Prolla TA, Bradshaw PC.

Biol Open. 2018 Nov 16;7(11). pii: bio033852. doi: 10.1242/bio.033852.

6.

In silico prediction of novel residues involved in amyloid primary nucleation of human I56T and D67H lysozyme.

Griffin JWD, Bradshaw PC.

BMC Struct Biol. 2018 Jul 20;18(1):9. doi: 10.1186/s12900-018-0088-1.

7.

In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer's Disease, Major Depressive Disorder, and Type 2 Diabetes.

Griffin JWD, Liu Y, Bradshaw PC, Wang K.

J Mol Neurosci. 2018 Mar;64(3):385-396. doi: 10.1007/s12031-018-1035-0. Epub 2018 Feb 13.

PMID:
29441491
8.

Individual Amino Acid Supplementation Can Improve Energy Metabolism and Decrease ROS Production in Neuronal Cells Overexpressing Alpha-Synuclein.

Delic V, Griffin JWD, Zivkovic S, Zhang Y, Phan TA, Gong H, Chaput D, Reynes C, Dinh VB, Cruz J, Cvitkovic E, Placides D, Frederic E, Mirzaei H, Stevens SM Jr, Jinwal U, Lee DC, Bradshaw PC.

Neuromolecular Med. 2017 Sep;19(2-3):322-344. doi: 10.1007/s12017-017-8448-8. Epub 2017 Jun 15.

PMID:
28620826
9.

Beneficial effects of a pyrroloquinolinequinone-containing dietary formulation on motor deficiency, cognitive decline and mitochondrial dysfunction in a mouse model of Alzheimer's disease.

Sawmiller D, Li S, Mori T, Habib A, Rongo D, Delic V, Bradshaw PC, Shytle RD, Sanberg C, Bickford P, Tan J.

Heliyon. 2017 Apr 4;3(4):e00279. doi: 10.1016/j.heliyon.2017.e00279. eCollection 2017 Apr.

10.

Ketone bodies mimic the life span extending properties of caloric restriction.

Veech RL, Bradshaw PC, Clarke K, Curtis W, Pawlosky R, King MT.

IUBMB Life. 2017 May;69(5):305-314. doi: 10.1002/iub.1627. Epub 2017 Apr 3. Review.

11.

Amino Acid Catabolism in Alzheimer's Disease Brain: Friend or Foe?

Griffin JW, Bradshaw PC.

Oxid Med Cell Longev. 2017;2017:5472792. doi: 10.1155/2017/5472792. Epub 2017 Feb 5. Review.

12.

Metabolome and proteome changes with aging in Caenorhabditis elegans.

Copes N, Edwards C, Chaput D, Saifee M, Barjuca I, Nelson D, Paraggio A, Saad P, Lipps D, Stevens SM Jr, Bradshaw PC.

Exp Gerontol. 2015 Dec;72:67-84. doi: 10.1016/j.exger.2015.09.013. Epub 2015 Sep 21.

13.

Prophylactic melatonin significantly reduces Alzheimer's neuropathology and associated cognitive deficits independent of antioxidant pathways in AβPP(swe)/PS1 mice.

O'Neal-Moffitt G, Delic V, Bradshaw PC, Olcese J.

Mol Neurodegener. 2015 Jul 11;10:27. doi: 10.1186/s13024-015-0027-6.

14.

Calorie restriction does not restore brain mitochondrial function in P301L tau mice, but it does decrease mitochondrial F0F1-ATPase activity.

Delic V, Brownlow M, Joly-Amado A, Zivkovic S, Noble K, Phan TA, Ta Y, Zhang Y, Bell SD, Kurien C, Reynes C, Morgan D, Bradshaw PC.

Mol Cell Neurosci. 2015 Jul;67:46-54. doi: 10.1016/j.mcn.2015.06.001. Epub 2015 Jun 3.

PMID:
26048366
15.

D-ß-hydroxybutyrate: an anti-aging ketone body.

Edwards C, Copes N, Bradshaw PC.

Oncotarget. 2015 Feb 28;6(6):3477-8. No abstract available.

16.

Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans.

Edwards C, Canfield J, Copes N, Brito A, Rehan M, Lipps D, Brunquell J, Westerheide SD, Bradshaw PC.

BMC Genet. 2015 Feb 3;16:8. doi: 10.1186/s12863-015-0167-2.

17.

D-beta-hydroxybutyrate extends lifespan in C. elegans.

Edwards C, Canfield J, Copes N, Rehan M, Lipps D, Bradshaw PC.

Aging (Albany NY). 2014 Aug;6(8):621-44.

18.

Measurement of the target-normal single-spin asymmetry in deep-inelastic scattering from the reaction (3)He(↑)(e,e')X.

Katich J, Qian X, Zhao YX, Allada K, Aniol K, Annand JR, Averett T, Benmokhtar F, Bertozzi W, Bradshaw PC, Bosted P, Camsonne A, Canan M, Cates GD, Chen C, Chen JP, Chen W, Chirapatpimol K, Chudakov E, Cisbani E, Cornejo JC, Cusanno F, Dalton MM, Deconinck W, de Jager CW, De Leo R, Deng X, Deur A, Ding H, Dolph PA, Dutta C, Dutta D, El Fassi L, Frullani S, Gao H, Garibaldi F, Gaskell D, Gilad S, Gilman R, Glamazdin O, Golge S, Guo L, Hamilton D, Hansen O, Higinbotham DW, Holmstrom T, Huang J, Huang M, Ibrahim HF, Iodice M, Jiang X, Jin G, Jones MK, Kelleher A, Kim W, Kolarkar A, Korsch W, LeRose JJ, Li X, Li Y, Lindgren R, Liyanage N, Long E, Lu HJ, Margaziotis DJ, Markowitz P, Marrone S, McNulty D, Meziani ZE, Michaels R, Moffit B, Muñoz Camacho C, Nanda S, Narayan A, Nelyubin V, Norum B, Oh Y, Osipenko M, Parno D, Peng JC, Phillips SK, Posik M, Puckett AJ, Qiang Y, Rakhman A, Ransome RD, Riordan S, Saha A, Sawatzky B, Schulte E, Shahinyan A, Shabestari MH, Širca S, Stepanyan S, Subedi R, Sulkosky V, Tang LG, Tobias A, Urciuoli GM, Vilardi I, Wang K, Wang Y, Wojtsekhowski B, Yan X, Yao H, Ye Y, Ye Z, Yuan L, Zhan X, Zhang Y, Zhang YW, Zhao B, Zheng X, Zhu L, Zhu X, Zong X.

Phys Rev Lett. 2014 Jul 11;113(2):022502. Epub 2014 Jul 11.

PMID:
25062169
19.

Characterization of the respiration-induced yeast mitochondrial permeability transition pore.

Bradshaw PC, Pfeiffer DR.

Yeast. 2013 Dec;30(12):471-83. doi: 10.1002/yea.2984.

20.

Malate and fumarate extend lifespan in Caenorhabditis elegans.

Edwards CB, Copes N, Brito AG, Canfield J, Bradshaw PC.

PLoS One. 2013;8(3):e58345. doi: 10.1371/journal.pone.0058345. Epub 2013 Mar 5.

21.

Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in Alzheimer's mice and cells.

Dragicevic N, Delic V, Cao C, Copes N, Lin X, Mamcarz M, Wang L, Arendash GW, Bradshaw PC.

Neuropharmacology. 2012 Dec;63(8):1368-79. doi: 10.1016/j.neuropharm.2012.08.018. Epub 2012 Sep 1.

PMID:
22959965
22.

Beam-target double-spin asymmetry A{LT} in charged pion production from deep inelastic scattering on a transversely polarized {3}He target at 1.4<Q{2}<2.7  GeV{2}.

Huang J, Allada K, Dutta C, Katich J, Qian X, Wang Y, Zhang Y, Aniol K, Annand JR, Averett T, Benmokhtar F, Bertozzi W, Bradshaw PC, Bosted P, Camsonne A, Canan M, Cates GD, Chen C, Chen JP, Chen W, Chirapatpimol K, Chudakov E, Cisbani E, Cornejo JC, Cusanno F, Dalton MM, Deconinck W, de Jager CW, De Leo R, Deng X, Deur A, Ding H, Dolph PA, Dutta D, El Fassi L, Frullani S, Gao H, Garibaldi F, Gaskell D, Gilad S, Gilman R, Glamazdin O, Golge S, Guo L, Hamilton D, Hansen O, Higinbotham DW, Holmstrom T, Huang M, Ibrahim HF, Iodice M, Jiang X, Jin G, Jones MK, Kelleher A, Kim W, Kolarkar A, Korsch W, Lerose JJ, Li X, Li Y, Lindgren R, Liyanage N, Long E, Lu HJ, Margaziotis DJ, Markowitz P, Marrone S, McNulty D, Meziani ZE, Michaels R, Moffit B, Muñoz Camacho C, Nanda S, Narayan A, Nelyubin V, Norum B, Oh Y, Osipenko M, Parno D, Peng JC, Phillips SK, Posik M, Puckett AJ, Qiang Y, Rakhman A, Ransome RD, Riordan S, Saha A, Sawatzky B, Schulte E, Shahinyan A, Shabestari MH, Sirca S, Stepanyan S, Subedi R, Sulkosky V, Tang LG, Tobias A, Urciuoli GM, Vilardi I, Wang K, Wojtsekhowski B, Yan X, Yao H, Ye Y, Ye Z, Yuan L, Zhan X, Zhang YW, Zhao B, Zheng X, Zhu L, Zhu X, Zong X; Jefferson Lab Hall A Collaboration.

Phys Rev Lett. 2012 Feb 3;108(5):052001. Epub 2012 Jan 30.

PMID:
22400926
23.

Single spin asymmetries in charged pion production from semi-inclusive deep inelastic scattering on a transversely polarized 3He Target at Q2 = 1.4-2.7 GeV2.

Qian X, Allada K, Dutta C, Huang J, Katich J, Wang Y, Zhang Y, Aniol K, Annand JR, Averett T, Benmokhtar F, Bertozzi W, Bradshaw PC, Bosted P, Camsonne A, Canan M, Cates GD, Chen C, Chen JP, Chen W, Chirapatpimol K, Chudakov E, Cisbani E, Cornejo JC, Cusanno F, Dalton MM, Deconinck W, de Jager CW, De Leo R, Deng X, Deur A, Ding H, Dolph PA, Dutta D, El Fassi L, Frullani S, Gao H, Garibaldi F, Gaskell D, Gilad S, Gilman R, Glamazdin O, Golge S, Guo L, Hamilton D, Hansen O, Higinbotham DW, Holmstrom T, Huang M, Ibrahim HF, Iodice M, Jiang X, Jin G, Jones MK, Kelleher A, Kim W, Kolarkar A, Korsch W, LeRose JJ, Li X, Li Y, Lindgren R, Liyanage N, Long E, Lu HJ, Margaziotis DJ, Markowitz P, Marrone S, McNulty D, Meziani ZE, Michaels R, Moffit B, Camacho CM, Nanda S, Narayan A, Nelyubin V, Norum B, Oh Y, Osipenko M, Parno D, Peng JC, Phillips SK, Posik M, Puckett AJ, Qiang Y, Rakhman A, Ransome RD, Riordan S, Saha A, Sawatzky B, Schulte E, Shahinyan A, Shabestari MH, Sirca S, Stepanyan S, Subedi R, Sulkosky V, Tang LG, Tobias A, Urciuoli GM, Vilardi I, Wang K, Wojtsekhowski B, Yan X, Yao H, Ye Y, Ye Z, Yuan L, Zhan X, Zhang YW, Zhao B, Zheng X, Zhu L, Zhu X, Zong X; Jefferson Lab Hall A Collaboration.

Phys Rev Lett. 2011 Aug 12;107(7):072003. Epub 2011 Aug 10.

PMID:
21902386
24.

Green tea epigallocatechin-3-gallate (EGCG) and other flavonoids reduce Alzheimer's amyloid-induced mitochondrial dysfunction.

Dragicevic N, Smith A, Lin X, Yuan F, Copes N, Delic V, Tan J, Cao C, Shytle RD, Bradshaw PC.

J Alzheimers Dis. 2011;26(3):507-21. doi: 10.3233/JAD-2011-101629.

PMID:
21694462
25.

Long-term electromagnetic field treatment enhances brain mitochondrial function of both Alzheimer's transgenic mice and normal mice: a mechanism for electromagnetic field-induced cognitive benefit?

Dragicevic N, Bradshaw PC, Mamcarz M, Lin X, Wang L, Cao C, Arendash GW.

Neuroscience. 2011 Jun 30;185:135-49. doi: 10.1016/j.neuroscience.2011.04.012. Epub 2011 Apr 13.

PMID:
21514369
26.

Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling.

Dragicevic N, Copes N, O'Neal-Moffitt G, Jin J, Buzzeo R, Mamcarz M, Tan J, Cao C, Olcese JM, Arendash GW, Bradshaw PC.

J Pineal Res. 2011 Aug;51(1):75-86. doi: 10.1111/j.1600-079X.2011.00864.x. Epub 2011 Mar 1.

PMID:
21355879
27.

Mitochondrial amyloid-beta levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice.

Dragicevic N, Mamcarz M, Zhu Y, Buzzeo R, Tan J, Arendash GW, Bradshaw PC.

J Alzheimers Dis. 2010;20 Suppl 2:S535-50. doi: 10.3233/JAD-2010-100342.

PMID:
20463404
28.

The role of mitochondrial DNA mutations in mammalian aging.

Kujoth GC, Bradshaw PC, Haroon S, Prolla TA.

PLoS Genet. 2007 Feb 23;3(2):e24. Review.

29.
30.

Loss of NAD(H) from swollen yeast mitochondria.

Bradshaw PC, Pfeiffer DR.

BMC Biochem. 2006 Jan 24;7:3.

32.

A computational model of mitochondrial AZT metabolism.

Bradshaw PC, Li J, Samuels DC.

Biochem J. 2005 Dec 1;392(Pt 2):363-73.

33.

A computational model of mitochondrial deoxynucleotide metabolism and DNA replication.

Bradshaw PC, Samuels DC.

Am J Physiol Cell Physiol. 2005 May;288(5):C989-1002. Epub 2005 Jan 5.

34.

Ca2+ transport in mitochondria from yeast expressing recombinant aequorin.

Jung DW, Bradshaw PC, Litsky M, Pfeiffer DR.

Anal Biochem. 2004 Jan 15;324(2):258-68.

PMID:
14690690
35.

Topology of the mitochondrial inner membrane: dynamics and bioenergetic implications.

Mannella CA, Pfeiffer DR, Bradshaw PC, Moraru II, Slepchenko B, Loew LM, Hsieh CE, Buttle K, Marko M.

IUBMB Life. 2001 Sep-Nov;52(3-5):93-100. Review.

36.

Free fatty acids activate a vigorous Ca(2+):2H(+) antiport activity in yeast mitochondria.

Bradshaw PC, Jung DW, Pfeiffer DR.

J Biol Chem. 2001 Nov 2;276(44):40502-9. Epub 2001 Jul 16.

37.

Properties of a cyclosporin-insensitive permeability transition pore in yeast mitochondria.

Jung DW, Bradshaw PC, Pfeiffer DR.

J Biol Chem. 1997 Aug 22;272(34):21104-12.

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