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Items: 42

1.

Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis.

Barrows NJ, Anglero-Rodriguez Y, Kim B, Jamison SF, Le Sommer C, McGee CE, Pearson JL, Dimopoulos G, Ascano M, Bradrick SS, Garcia-Blanco MA.

Sci Rep. 2019 Jul 4;9(1):9711. doi: 10.1038/s41598-019-45910-9.

2.

Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA.

Soto-Acosta R, Xie X, Shan C, Baker CK, Shi PY, Rossi SL, Garcia-Blanco MA, Bradrick S.

Elife. 2018 Dec 4;7. pii: e39023. doi: 10.7554/eLife.39023.

3.

Staufen1 Interacts with Multiple Components of the Ebola Virus Ribonucleoprotein and Enhances Viral RNA Synthesis.

Fang J, Pietzsch C, Ramanathan P, Santos RI, Ilinykh PA, Garcia-Blanco MA, Bukreyev A, Bradrick SS.

MBio. 2018 Oct 9;9(5). pii: e01771-18. doi: 10.1128/mBio.01771-18.

4.

Biochemistry and Molecular Biology of Flaviviruses.

Barrows NJ, Campos RK, Liao KC, Prasanth KR, Soto-Acosta R, Yeh SC, Schott-Lerner G, Pompon J, Sessions OM, Bradrick SS, Garcia-Blanco MA.

Chem Rev. 2018 Apr 25;118(8):4448-4482. doi: 10.1021/acs.chemrev.7b00719. Epub 2018 Apr 13. Review.

5.

Dengue Virus Selectively Annexes Endoplasmic Reticulum-Associated Translation Machinery as a Strategy for Co-opting Host Cell Protein Synthesis.

Reid DW, Campos RK, Child JR, Zheng T, Chan KWK, Bradrick SS, Vasudevan SG, Garcia-Blanco MA, Nicchitta CV.

J Virol. 2018 Mar 14;92(7). pii: e01766-17. doi: 10.1128/JVI.01766-17. Print 2018 Apr 1.

6.

Causes and Consequences of Flavivirus RNA Methylation.

Bradrick SS.

Front Microbiol. 2017 Dec 5;8:2374. doi: 10.3389/fmicb.2017.02374. eCollection 2017. Review.

7.

Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission.

Pompon J, Manuel M, Ng GK, Wong B, Shan C, Manokaran G, Soto-Acosta R, Bradrick SS, Ooi EE, Missé D, Shi PY, Garcia-Blanco MA.

PLoS Pathog. 2017 Jul 28;13(7):e1006535. doi: 10.1371/journal.ppat.1006535. eCollection 2017 Jul.

8.

Roles of Pro-viral Host Factors in Mosquito-Borne Flavivirus Infections.

Campos RK, Garcia-Blanco MA, Bradrick SS.

Curr Top Microbiol Immunol. 2018;419:43-67. doi: 10.1007/82_2017_26. Review.

PMID:
28688087
9.

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network.

Aliota MT, Bassit L, Bradrick SS, Cox B, Garcia-Blanco MA, Gavegnano C, Friedrich TC, Golos TG, Griffin DE, Haddow AD, Kallas EG, Kitron U, Lecuit M, Magnani DM, Marrs C, Mercer N, McSweegan E, Ng LFP, O'Connor DH, Osorio JE, Ribeiro GS, Ricciardi M, Rossi SL, Saade G, Schinazi RF, Schott-Lerner GO, Shan C, Shi PY, Watkins DI, Vasilakis N, Weaver SC.

Antiviral Res. 2017 Aug;144:223-246. doi: 10.1016/j.antiviral.2017.06.001. Epub 2017 Jun 6. Review.

10.

The 5' and 3' Untranslated Regions of the Flaviviral Genome.

Ng WC, Soto-Acosta R, Bradrick SS, Garcia-Blanco MA, Ooi EE.

Viruses. 2017 Jun 6;9(6). pii: E137. doi: 10.3390/v9060137. Review.

11.

Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk.

Galarza-Muñoz G, Briggs FBS, Evsyukova I, Schott-Lerner G, Kennedy EM, Nyanhete T, Wang L, Bergamaschi L, Widen SG, Tomaras GD, Ko DC, Bradrick SS, Barcellos LF, Gregory SG, Garcia-Blanco MA.

Cell. 2017 Mar 23;169(1):72-84.e13. doi: 10.1016/j.cell.2017.03.007.

12.

RPLP1 and RPLP2 Are Essential Flavivirus Host Factors That Promote Early Viral Protein Accumulation.

Campos RK, Wong B, Xie X, Lu YF, Shi PY, Pompon J, Garcia-Blanco MA, Bradrick SS.

J Virol. 2017 Jan 31;91(4). pii: e01706-16. doi: 10.1128/JVI.01706-16. Print 2017 Feb 15.

13.

N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection.

Gokhale NS, McIntyre ABR, McFadden MJ, Roder AE, Kennedy EM, Gandara JA, Hopcraft SE, Quicke KM, Vazquez C, Willer J, Ilkayeva OR, Law BA, Holley CL, Garcia-Blanco MA, Evans MJ, Suthar MS, Bradrick SS, Mason CE, Horner SM.

Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.

14.

The Golgi associated ERI3 is a Flavivirus host factor.

Ward AM, Calvert ME, Read LR, Kang S, Levitt BE, Dimopoulos G, Bradrick SS, Gunaratne J, Garcia-Blanco MA.

Sci Rep. 2016 Sep 29;6:34379. doi: 10.1038/srep34379.

15.

Flavivirus RNA transactions from viral entry to genome replication.

Garcia-Blanco MA, Vasudevan SG, Bradrick SS, Nicchitta C.

Antiviral Res. 2016 Oct;134:244-249. doi: 10.1016/j.antiviral.2016.09.010. Epub 2016 Sep 22. Review.

PMID:
27666184
16.

Inhibition of microRNA 128 promotes excitability of cultured cortical neuronal networks.

McSweeney KM, Gussow AB, Bradrick SS, Dugger SA, Gelfman S, Wang Q, Petrovski S, Frankel WN, Boland MJ, Goldstein DB.

Genome Res. 2016 Oct;26(10):1411-1416. Epub 2016 Aug 11.

17.

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection.

Barrows NJ, Campos RK, Powell ST, Prasanth KR, Schott-Lerner G, Soto-Acosta R, Galarza-Muñoz G, McGrath EL, Urrabaz-Garza R, Gao J, Wu P, Menon R, Saade G, Fernandez-Salas I, Rossi SL, Vasilakis N, Routh A, Bradrick SS, Garcia-Blanco MA.

Cell Host Microbe. 2016 Aug 10;20(2):259-70. doi: 10.1016/j.chom.2016.07.004. Epub 2016 Jul 28.

18.

Epileptic encephalopathy-causing mutations in DNM1 impair synaptic vesicle endocytosis.

Dhindsa RS, Bradrick SS, Yao X, Heinzen EL, Petrovski S, Krueger BJ, Johnson MR, Frankel WN, Petrou S, Boumil RM, Goldstein DB.

Neurol Genet. 2015 Apr 17;1(1):e4. doi: 10.1212/01.NXG.0000464295.65736.da. eCollection 2015 Jun.

19.

Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication.

Phillips SL, Soderblom EJ, Bradrick SS, Garcia-Blanco MA.

MBio. 2016 Jan 5;7(1):e01865-15. doi: 10.1128/mBio.01865-15.

20.

RNA-based methods in virology.

Bradrick SS, Garcia-Blanco MA.

Methods. 2015 Dec;91:1-2. doi: 10.1016/j.ymeth.2015.11.014. No abstract available.

PMID:
26678321
21.

IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearance.

Lu YF, Mauger DM, Goldstein DB, Urban TJ, Weeks KM, Bradrick SS.

Sci Rep. 2015 Nov 4;5:16037. doi: 10.1038/srep16037.

22.

Antisense-mediated affinity purification of dengue virus ribonucleoprotein complexes from infected cells.

Phillips SL, Garcia-Blanco MA, Bradrick SS.

Methods. 2015 Dec;91:13-19. doi: 10.1016/j.ymeth.2015.08.008. Epub 2015 Aug 12.

23.

XRN1 stalling in the 5' UTR of Hepatitis C virus and Bovine Viral Diarrhea virus is associated with dysregulated host mRNA stability.

Moon SL, Blackinton JG, Anderson JR, Dozier MK, Dodd BJ, Keene JD, Wilusz CJ, Bradrick SS, Wilusz J.

PLoS Pathog. 2015 Mar 6;11(3):e1004708. doi: 10.1371/journal.ppat.1004708. eCollection 2015 Mar.

24.

Interferon-λ4 is a cell-autonomous type III interferon associated with pre-treatment hepatitis C virus burden.

Lu YF, Goldstein DB, Urban TJ, Bradrick SS.

Virology. 2015 Feb;476:334-340. doi: 10.1016/j.virol.2014.12.020. Epub 2015 Jan 9.

25.

Induction of viral, 7-methyl-guanosine cap-independent translation and oncolysis by mitogen-activated protein kinase-interacting kinase-mediated effects on the serine/arginine-rich protein kinase.

Brown MC, Bryant JD, Dobrikova EY, Shveygert M, Bradrick SS, Chandramohan V, Bigner DD, Gromeier M.

J Virol. 2014 Nov;88(22):13135-48. doi: 10.1128/JVI.01883-14. Epub 2014 Sep 3.

26.

Functional genomics approach for the identification of human host factors supporting dengue viral propagation.

Barrows NJ, Jamison SF, Bradrick SS, Le Sommer C, Kim SY, Pearson J, Garcia-Blanco MA.

Methods Mol Biol. 2014;1138:285-99. doi: 10.1007/978-1-4939-0348-1_18.

27.

A miRNA-responsive cell-free translation system facilitates isolation of hepatitis C virus miRNP complexes.

Bradrick SS, Nagyal S, Novatt H.

RNA. 2013 Aug;19(8):1159-69. doi: 10.1261/rna.038810.113. Epub 2013 Jun 21.

28.

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.

Evsyukova I, Bradrick SS, Gregory SG, Garcia-Blanco MA.

RNA. 2013 Jan;19(1):103-15. doi: 10.1261/rna.035410.112. Epub 2012 Nov 14.

29.

G protein-coupled receptor kinase 2 promotes flaviviridae entry and replication.

Le Sommer C, Barrows NJ, Bradrick SS, Pearson JL, Garcia-Blanco MA.

PLoS Negl Trop Dis. 2012;6(9):e1820. doi: 10.1371/journal.pntd.0001820. Epub 2012 Sep 13.

30.

Gemin5 proteolysis reveals a novel motif to identify L protease targets.

Piñeiro D, Ramajo J, Bradrick SS, Martínez-Salas E.

Nucleic Acids Res. 2012 Jun;40(11):4942-53. doi: 10.1093/nar/gks172. Epub 2012 Feb 22.

31.

Up-regulation of Hedgehog pathway is associated with cellular permissiveness for hepatitis C virus replication.

Choi SS, Bradrick S, Qiang G, Mostafavi A, Chaturvedi G, Weinman SA, Diehl AM, Jhaveri R.

Hepatology. 2011 Nov;54(5):1580-90. doi: 10.1002/hep.24576.

32.

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

Urban TJ, Thompson AJ, Bradrick SS, Fellay J, Schuppan D, Cronin KD, Hong L, McKenzie A, Patel K, Shianna KV, McHutchison JG, Goldstein DB, Afdhal N.

Hepatology. 2010 Dec;52(6):1888-96. doi: 10.1002/hep.23912. Epub 2010 Oct 7.

33.

Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction.

Shveygert M, Kaiser C, Bradrick SS, Gromeier M.

Mol Cell Biol. 2010 Nov;30(21):5160-7. doi: 10.1128/MCB.00448-10. Epub 2010 Sep 7.

34.

Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma.

Pereira Tde A, Witek RP, Syn WK, Choi SS, Bradrick S, Karaca GF, Agboola KM, Jung Y, Omenetti A, Moylan CA, Yang L, Fernandez-Zapico ME, Jhaveri R, Shah VH, Pereira FE, Diehl AM.

Lab Invest. 2010 Dec;90(12):1690-703. doi: 10.1038/labinvest.2010.147. Epub 2010 Aug 9.

35.

Poly(A)-binding protein modulates mRNA susceptibility to cap-dependent miRNA-mediated repression.

Walters RW, Bradrick SS, Gromeier M.

RNA. 2010 Jan;16(1):239-50. doi: 10.1261/rna.1795410. Epub 2009 Nov 24.

36.

Identification of gemin5 as a novel 7-methylguanosine cap-binding protein.

Bradrick SS, Gromeier M.

PLoS One. 2009 Sep 14;4(9):e7030. doi: 10.1371/journal.pone.0007030.

37.

Activation of cap-independent translation by variant eukaryotic initiation factor 4G in vivo.

Kaiser C, Dobrikova EY, Bradrick SS, Shveygert M, Herbert JT, Gromeier M.

RNA. 2008 Oct;14(10):2170-82. doi: 10.1261/rna.1171808. Epub 2008 Aug 28.

38.

Poly(A)-binding protein is differentially required for translation mediated by viral internal ribosome entry sites.

Bradrick SS, Dobrikova EY, Kaiser C, Shveygert M, Gromeier M.

RNA. 2007 Sep;13(9):1582-93. Epub 2007 Jul 25.

39.

The hepatitis C virus 3'-untranslated region or a poly(A) tract promote efficient translation subsequent to the initiation phase.

Bradrick SS, Walters RW, Gromeier M.

Nucleic Acids Res. 2006 Mar 1;34(4):1293-303. Print 2006.

40.

Activity of a type 1 picornavirus internal ribosomal entry site is determined by sequences within the 3' nontranslated region.

Dobrikova E, Florez P, Bradrick S, Gromeier M.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15125-30. Epub 2003 Nov 26.

41.

The stem loop II within the 5' nontranslated region of clinical coxsackievirus B3 genomes determines cardiovirulence phenotype in a murine model.

Dunn JJ, Bradrick SS, Chapman NM, Tracy SM, Romero JR.

J Infect Dis. 2003 May 15;187(10):1552-61. Epub 2003 Apr 30.

PMID:
12721935

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