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Items: 1 to 50 of 279

1.

The nutritional herb Epimedium grandiflorum inhibits the growth in a model for the Luminal A molecular subtype of breast cancer.

Telang NT, Li G, Katdare M, Sepkovic DW, Bradlow HL, Wong GYC.

Oncol Lett. 2017 Apr;13(4):2477-2482. doi: 10.3892/ol.2017.5720. Epub 2017 Feb 13.

2.

The effect of oral 3,3'-diindolylmethane supplementation on the 2:16α-OHE ratio in BRCA1 mutation carriers.

Nikitina D, Llacuachaqui M, Sepkovic D, Bradlow HL, Narod SA, Kotsopoulos J.

Fam Cancer. 2015 Jun;14(2):281-6. doi: 10.1007/s10689-015-9783-2.

PMID:
25613194
3.

Obesity and the gut microbiome: pathophysiological aspects.

Bradlow HL.

Horm Mol Biol Clin Investig. 2014 Jan;17(1):53-61. doi: 10.1515/hmbci-2013-0063. Review.

PMID:
25372730
4.

Comparative efficacy of extracts from Lycium barbarum bark and fruit on estrogen receptor positive human mammary carcinoma MCF-7 cells.

Telang N, Li G, Sepkovic D, Bradlow HL, Wong GY.

Nutr Cancer. 2014;66(2):278-84. doi: 10.1080/01635581.2014.864776. Epub 2013 Dec 30.

PMID:
24377707
5.

Evaluation of 3,3'-diindolylmethane with gardasil quadrivalent HPV vaccine in K14-HPV16-transgenic mice cervical histology.

Sepkovic DW, Pagan DV, Stein J, Carlisle AD, Ksieski HB, Auborn K, Nyirenda T, Bradlow HL.

In Vivo. 2013 May-Jun;27(3):299-304.

PMID:
23606684
6.

Polychlorinated biphenyl exposure, diabetes and endogenous hormones: a cross-sectional study in men previously employed at a capacitor manufacturing plant.

Persky V, Piorkowski J, Turyk M, Freels S, Chatterton R Jr, Dimos J, Bradlow HL, Chary LK, Burse V, Unterman T, Sepkovic DW, McCann K.

Environ Health. 2012 Aug 29;11:57.

7.

3,3'-Diindolylmethane increases serum interferon-γ levels in the K14-HPV16 transgenic mouse model for cervical cancer.

Sepkovic DW, Raucci L, Stein J, Carlisle AD, Auborn K, Ksieski HB, Nyirenda T, Bradlow HL.

In Vivo. 2012 Mar-Apr;26(2):207-11.

PMID:
22351660
8.

Anti-proliferative effects of Chinese herb Cornus officinalis in a cell culture model for estrogen receptor-positive clinical breast cancer.

Telang NT, Li G, Sepkovic DW, Bradlow HL, Wong GY.

Mol Med Rep. 2012 Jan;5(1):22-8. doi: 10.3892/mmr.2011.617. Epub 2011 Oct 4.

PMID:
21971582
9.
10.

Associations of polychlorinated biphenyl exposure and endogenous hormones with diabetes in post-menopausal women previously employed at a capacitor manufacturing plant.

Persky V, Piorkowski J, Turyk M, Freels S, Chatterton R Jr, Dimos J, Bradlow HL, Chary LK, Burse V, Unterman T, Sepkovic D, McCann K.

Environ Res. 2011 Aug;111(6):817-24. doi: 10.1016/j.envres.2011.05.012.

PMID:
21684538
11.

Results from a dose-response study using 3,3'-diindolylmethane in the K14-HPV16 transgenic mouse model: cervical histology.

Sepkovic DW, Stein J, Carlisle AD, Ksieski HB, Auborn K, Raucci L, Nyirenda T, Bradlow HL.

Cancer Prev Res (Phila). 2011 Jun;4(6):890-6. doi: 10.1158/1940-6207.CAPR-10-0369. Epub 2011 Mar 7.

12.

3,3'-diindolylmethane modulates estrogen metabolism in patients with thyroid proliferative disease: a pilot study.

Rajoria S, Suriano R, Parmar PS, Wilson YL, Megwalu U, Moscatello A, Bradlow HL, Sepkovic DW, Geliebter J, Schantz SP, Tiwari RK.

Thyroid. 2011 Mar;21(3):299-304. doi: 10.1089/thy.2010.0245. Epub 2011 Jan 22.

13.
14.

Diindolylmethane inhibits cervical dysplasia, alters estrogen metabolism, and enhances immune response in the K14-HPV16 transgenic mouse model.

Sepkovic DW, Stein J, Carlisle AD, Ksieski HB, Auborn K, Bradlow HL.

Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2957-64. doi: 10.1158/1055-9965.EPI-09-0698. Epub 2009 Oct 27. Erratum in: Cancer Epidemiol Biomarkers Prev. 2010 Feb;19(2):628.

15.

Lycium barbarum inhibits growth of estrogen receptor positive human breast cancer cells by favorably altering estradiol metabolism.

Li G, Sepkovic DW, Bradlow HL, Telang NT, Wong GY.

Nutr Cancer. 2009;61(3):408-14. doi: 10.1080/01635580802585952.

PMID:
19373615
16.

Clues to understanding the oxidation of estradiol in humans: effects of acute infectious hepatitis, autoimmune hepatitis, and chronic liver disease.

Lahita RG, Schaefer RA, Bradlow HL, Kreek MJ.

Ann N Y Acad Sci. 2009 Feb;1155:242-51. doi: 10.1111/j.1749-6632.2009.04359.x.

17.

Estrogen hydroxylation--the good and the bad.

Sepkovic DW, Bradlow HL.

Ann N Y Acad Sci. 2009 Feb;1155:57-67. doi: 10.1111/j.1749-6632.2008.03675.x. Review.

PMID:
19250192
18.

3,3'-Diindolylmethane and genistein decrease the adverse effects of estrogen in LNCaP and PC-3 prostate cancer cells.

Smith S, Sepkovic D, Bradlow HL, Auborn KJ.

J Nutr. 2008 Dec;138(12):2379-85. doi: 10.3945/jn.108.090993.

19.
20.

Variants in estrogen metabolism and biosynthesis genes and urinary estrogen metabolites in women with a family history of breast cancer.

Greenlee H, Chen Y, Kabat GC, Wang Q, Kibriya MG, Gurvich I, Sepkovic DW, Bradlow HL, Senie RT, Santella RM, Ahsan H.

Breast Cancer Res Treat. 2007 Mar;102(1):111-7. Epub 2006 Jul 19.

PMID:
16850246
21.

Estrogen metabolism and breast cancer.

Kabat GC, O'Leary ES, Gammon MD, Sepkovic DW, Teitelbaum SL, Britton JA, Terry MB, Neugut AI, Bradlow HL.

Epidemiology. 2006 Jan;17(1):80-8.

PMID:
16357599
22.

A common CYP1B1 polymorphism is associated with 2-OHE1/16-OHE1 urinary estrone ratio.

Paracchini V, Pedotti P, Raimondi S, Garte S, Bradlow HL, Sepkovic DW, Taioli E.

Clin Chem Lab Med. 2005;43(7):702-6.

PMID:
16207128
23.

Comparison of plasma and urinary levels of 2-hydroxyestrogen and 16 alpha-hydroxyestrogen metabolites.

Bradlow HL, Jernström H, Sepkovic DW, Klug TL, Narod SA.

Mol Genet Metab. 2006 Feb;87(2):135-46. Epub 2005 Sep 13.

PMID:
16165383
24.

Urinary estrogen metabolites and their ratio among Asian American women.

Falk RT, Fears TR, Xu X, Hoover RN, Pike MC, Wu AH, Nomura AM, Kolonel LN, West DW, Sepkovic DW, Bradlow HL, Ziegler RG.

Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):221-6.

25.

Steroids as procarcinogenic agents.

Bradlow HL, Sepkovic DW.

Ann N Y Acad Sci. 2004 Dec;1028:216-32. Review.

PMID:
15650248
26.
27.

Influence of postmenopausal hormone replacement therapy on an estrogen metabolite biomarker of risk for breast cancer.

Alvarez-Vasquez RB, Axelrod D, Frenkel K, Newman MC, Sepkovic DW, Bradlow HL, Zumoff B.

Horm Metab Res. 2003 Jun;35(6):358-61.

PMID:
12920658
28.

Predictors of the plasma ratio of 2-hydroxyestrone to 16alpha-hydroxyestrone among pre-menopausal, nulliparous women from four ethnic groups.

Jernström H, Klug TL, Sepkovic DW, Bradlow HL, Narod SA.

Carcinogenesis. 2003 May;24(5):991-1005.

PMID:
12771045
29.

Urinary estrogen metabolites and breast cancer: differential pattern of risk found with pre- versus post-treatment collection.

Fowke JH, Qi D, Bradlow HL, Shu XO, Gao YT, Cheng JR, Jin F, Zheng W.

Steroids. 2003 Jan;68(1):65-72.

PMID:
12475724
30.

The Long Island Breast Cancer Study Project: description of a multi-institutional collaboration to identify environmental risk factors for breast cancer.

Gammon MD, Neugut AI, Santella RM, Teitelbaum SL, Britton JA, Terry MB, Eng SM, Wolff MS, Stellman SD, Kabat GC, Levin B, Bradlow HL, Hatch M, Beyea J, Camann D, Trent M, Senie RT, Garbowski GC, Maffeo C, Montalvan P, Berkowitz GS, Kemeny M, Citron M, Schnabe F, Schuss A, Hajdu S, Vincguerra V, Collman GW, Obrams GI.

Breast Cancer Res Treat. 2002 Jun;74(3):235-54.

PMID:
12206514
31.

Environmental toxins and breast cancer on Long Island. II. Organochlorine compound levels in blood.

Gammon MD, Wolff MS, Neugut AI, Eng SM, Teitelbaum SL, Britton JA, Terry MB, Levin B, Stellman SD, Kabat GC, Hatch M, Senie R, Berkowitz G, Bradlow HL, Garbowski G, Maffeo C, Montalvan P, Kemeny M, Citron M, Schnabel F, Schuss A, Hajdu S, Vinceguerra V, Niguidula N, Ireland K, Santella RM.

Cancer Epidemiol Biomarkers Prev. 2002 Aug;11(8):686-97.

32.

Altered neuroendocrine immune (NEI) networks in rheumatology.

Cutolo M, Bijlsma JW, Lahita RG, Masi AT, Straub RH, Bradlow HL.

Ann N Y Acad Sci. 2002 Jun;966:xiii-xviii. Review. No abstract available.

PMID:
12114252
33.

Diet and breast cancer.

Bradlow HL, Sepkovic DW.

Ann N Y Acad Sci. 2002 Jun;963:247-67.

PMID:
12095951
34.

Quantitative determination of 3,3'-diindolylmethane in urine of individuals receiving indole-3-carbinol.

Sepkovic DW, Bradlow HL, Bell M.

Nutr Cancer. 2001;41(1-2):57-63.

PMID:
12094629
35.

Abrogation of estrogen-mediated cellular and biochemical effects by indole-3-carbinol.

Ashok BT, Chen Y, Liu X, Bradlow HL, Mittelman A, Tiwari RK.

Nutr Cancer. 2001;41(1-2):180-7.

PMID:
12094623
36.

Effect of soy protein on endogenous hormones in postmenopausal women.

Persky VW, Turyk ME, Wang L, Freels S, Chatterton R Jr, Barnes S, Erdman J Jr, Sepkovic DW, Bradlow HL, Potter S.

Am J Clin Nutr. 2002 Jan;75(1):145-53. Erratum in: Am J Clin Nutr 2002 Sep;76(3):695.

PMID:
11756072
37.
38.

Urinary estrogen metabolites and mammographic parenchymal patterns in postmenopausal women.

Riza E, dos Santos Silva I, De Stavola B, Bradlow HL, Sepkovic DW, Linos D, Linos A.

Cancer Epidemiol Biomarkers Prev. 2001 Jun;10(6):627-34.

39.

Reciprocal expression of ERalpha and ERbeta is associated with estrogen-mediated modulation of intestinal tumorigenesis.

Weyant MJ, Carothers AM, Mahmoud NN, Bradlow HL, Remotti H, Bilinski RT, Bertagnolli MM.

Cancer Res. 2001 Mar 15;61(6):2547-51.

40.

Re: CYP17 promoter polymorphism and breast cancer in Australian women under age forty years.

Jernström H, Vesprini D, Bradlow HL, Narod SA.

J Natl Cancer Inst. 2001 Apr 4;93(7):554-5. No abstract available.

PMID:
11287451
41.

Estrogen metabolism as a risk factor for head and neck cancer.

Yoo HJ, Sepkovic DW, Bradlow HL, Yu GP, Sirilian HV, Schantz SP.

Otolaryngol Head Neck Surg. 2001 Mar;124(3):241-7.

PMID:
11240983
42.

Estrone and estradiol metabolism in vivo in human breast cysts.

Raju U, Sepkovic DW, Miller WR, Dixon JM, Bradlow HL, Levitz M.

Steroids. 2000 Dec;65(12):883-8.

PMID:
11077086
43.

Estrogen metabolism and risk of breast cancer: a prospective study of the 2:16alpha-hydroxyestrone ratio in premenopausal and postmenopausal women.

Muti P, Bradlow HL, Micheli A, Krogh V, Freudenheim JL, Schünemann HJ, Stanulla M, Yang J, Sepkovic DW, Trevisan M, Berrino F.

Epidemiology. 2000 Nov;11(6):635-40.

PMID:
11055622
44.

Feeding DHEA to C57/B167 mice.

Bradlow HL.

Proc Soc Exp Biol Med. 2000 Sep;224(4):201-2. No abstract available.

PMID:
10964250
45.

Placebo-controlled trial of indole-3-carbinol in the treatment of CIN.

Bell MC, Crowley-Nowick P, Bradlow HL, Sepkovic DW, Schmidt-Grimminger D, Howell P, Mayeaux EJ, Tucker A, Turbat-Herrera EA, Mathis JM.

Gynecol Oncol. 2000 Aug;78(2):123-9.

PMID:
10926790
46.

Phytochemicals as modulators of cancer risk.

Bradlow HL, Telang NT, Sepkovic DW, Osborne MP.

Adv Exp Med Biol. 1999;472:207-21. Review.

PMID:
10736628
47.

Endocrine characteristics of human breast epithelial cells, MCF-10F.

Singhal H, Guo L, Bradlow HL, Mittelman A, Tiwari RK.

Horm Res. 1999;52(4):171-7.

PMID:
10725782
48.

Multifunctional aspects of the action of indole-3-carbinol as an antitumor agent.

Bradlow HL, Sepkovic DW, Telang NT, Osborne MP.

Ann N Y Acad Sci. 1999;889:204-13. Review.

PMID:
10668495
49.

A new ELISA kit for measuring urinary 2-hydroxyestrone, 16alpha-hydroxyestrone, and their ratio: reproducibility, validity, and assay performance after freeze-thaw cycling and preservation by boric acid.

Falk RT, Rossi SC, Fears TR, Sepkovic DW, Migella A, Adlercreutz H, Donaldson J, Bradlow HL, Ziegler RG.

Cancer Epidemiol Biomarkers Prev. 2000 Jan;9(1):81-7.

50.

Reproducibility of plasma and urinary sex hormone levels in premenopausal women over a one-year period.

Michaud DS, Manson JE, Spiegelman D, Barbieri RL, Sepkovic DW, Bradlow HL, Hankinson SE.

Cancer Epidemiol Biomarkers Prev. 1999 Dec;8(12):1059-64.

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