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Items: 20


Superion(®) InterSpinous Spacer for treatment of moderate degenerative lumbar spinal stenosis: durable three-year results of a randomized controlled trial.

Patel VV, Nunley PD, Whang PG, Haley TR, Bradley WD, Davis RP, Block JE, Geisler FH.

J Pain Res. 2015 Oct 3;8:657-62. doi: 10.2147/JPR.S92633. eCollection 2015.


Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase.

Simpson MA, Bradley WD, Harburger D, Parsons M, Calderwood DA, Koleske AJ.

J Biol Chem. 2015 Mar 27;290(13):8360-72. doi: 10.1074/jbc.M115.638874. Epub 2015 Feb 18.


Superion interspinous process spacer for intermittent neurogenic claudication secondary to moderate lumbar spinal stenosis: two-year results from a randomized controlled FDA-IDE pivotal trial.

Patel VV, Whang PG, Haley TR, Bradley WD, Nunley PD, Davis RP, Miller LE, Block JE, Geisler FH.

Spine (Phila Pa 1976). 2015 Mar 1;40(5):275-82. doi: 10.1097/BRS.0000000000000735.


EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation.

Bradley WD, Arora S, Busby J, Balasubramanian S, Gehling VS, Nasveschuk CG, Vaswani RG, Yuan CC, Hatton C, Zhao F, Williamson KE, Iyer P, Méndez J, Campbell R, Cantone N, Garapaty-Rao S, Audia JE, Cook AS, Dakin LA, Albrecht BK, Harmange JC, Daniels DL, Cummings RT, Bryant BM, Normant E, Trojer P.

Chem Biol. 2014 Nov 20;21(11):1463-75. doi: 10.1016/j.chembiol.2014.09.017.


Two-year clinical outcomes of a multicenter randomized controlled trial comparing two interspinous spacers for treatment of moderate lumbar spinal stenosis.

Patel VV, Whang PG, Haley TR, Bradley WD, Nunley PD, Miller LE, Block JE, Geisler FH.

BMC Musculoskelet Disord. 2014 Jul 5;15:221. doi: 10.1186/1471-2474-15-221.


Transsacral axial interbody fusion.

Tobler WD, Melgar MA, Raley TJ, Bradley WD, Miller LE, Nasca RJ.

J Neurosurg Spine. 2014 May;20(5):599-600; author reply 600-1. doi: 10.3171/2013.11.SPINE13981. Epub 2014 Mar 14. No abstract available.


Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior.

Warren MS, Bradley WD, Gourley SL, Lin YC, Simpson MA, Reichardt LF, Greer CA, Taylor JR, Koleske AJ.

J Neurosci. 2012 Feb 22;32(8):2824-34. doi: 10.1523/JNEUROSCI.3942-11.2012.


Minimally invasive trans-sacral approach to L5-S1 interbody fusion: Preliminary results from 1 center and review of the literature.

Bradley WD, Hisey MS, Verma-Kurvari S, Ohnmeiss DD.

Int J Spine Surg. 2012 Dec 1;6:110-4. doi: 10.1016/j.ijsp.2011.12.005. eCollection 2012.


Resistance to selective BRAF inhibition can be mediated by modest upstream pathway activation.

Su F, Bradley WD, Wang Q, Yang H, Xu L, Higgins B, Kolinsky K, Packman K, Kim MJ, Trunzer K, Lee RJ, Schostack K, Carter J, Albert T, Germer S, Rosinski J, Martin M, Simcox ME, Lestini B, Heimbrook D, Bollag G.

Cancer Res. 2012 Feb 15;72(4):969-78. doi: 10.1158/0008-5472.CAN-11-1875. Epub 2011 Dec 28.


Antitumor activity of BRAF inhibitor vemurafenib in preclinical models of BRAF-mutant colorectal cancer.

Yang H, Higgins B, Kolinsky K, Packman K, Bradley WD, Lee RJ, Schostack K, Simcox ME, Kopetz S, Heimbrook D, Lestini B, Bollag G, Su F.

Cancer Res. 2012 Feb 1;72(3):779-89. doi: 10.1158/0008-5472.CAN-11-2941. Epub 2011 Dec 16.


The emerging role of the intestine in metabolic diseases.

Bradley WD, Zwingelstein C, Rondinone CM.

Arch Physiol Biochem. 2011 Jul;117(3):165-76. doi: 10.3109/13813455.2011.578651. Review.


Minimally invasive axial presacral L5-S1 interbody fusion: two-year clinical and radiographic outcomes.

Tobler WD, Gerszten PC, Bradley WD, Raley TJ, Nasca RJ, Block JE.

Spine (Phila Pa 1976). 2011 Sep 15;36(20):E1296-301. doi: 10.1097/BRS.0b013e31821b3e37.


Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts.

Bradley WD, Koleske AJ.

J Cell Sci. 2009 Oct 1;122(Pt 19):3441-54. doi: 10.1242/jcs.039859.


Inhibition of Rho via Arg and p190RhoGAP in the postnatal mouse hippocampus regulates dendritic spine maturation, synapse and dendrite stability, and behavior.

Sfakianos MK, Eisman A, Gourley SL, Bradley WD, Scheetz AJ, Settleman J, Taylor JR, Greer CA, Williamson A, Koleske AJ.

J Neurosci. 2007 Oct 10;27(41):10982-92.


The Abl-related gene tyrosine kinase acts through p190RhoGAP to inhibit actomyosin contractility and regulate focal adhesion dynamics upon adhesion to fibronectin.

Peacock JG, Miller AL, Bradley WD, Rodriguez OC, Webb DJ, Koleske AJ.

Mol Biol Cell. 2007 Oct;18(10):3860-72. Epub 2007 Jul 25.


Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane.

Bradley WD, Hernández SE, Settleman J, Koleske AJ.

Mol Biol Cell. 2006 Nov;17(11):4827-36. Epub 2006 Sep 13.


Mechanism of action of a novel viral mutagenic covert nucleotide: molecular interactions with HIV-1 reverse transcriptase and host cell DNA polymerases.

Murakami E, Basavapathruni A, Bradley WD, Anderson KS.

Antiviral Res. 2005 Jul;67(1):10-7. Epub 2005 Jan 26.


Optimizing the interfacial binding and activity of a bacterial phosphatidylinositol-specific phospholipase C.

Feng J, Bradley WD, Roberts MF.

J Biol Chem. 2003 Jul 4;278(27):24651-7. Epub 2003 Apr 24.


Mechanical strength of scaphoid fixation.

Newport ML, Williams CD, Bradley WD.

J Hand Surg Br. 1996 Feb;21(1):99-102.


Leiomyosarcoma of the femoral vein in a marathon runner.

Bradley WD, Fields KB, Delaney MJ.

J Am Board Fam Pract. 1992 Mar-Apr;5(2):219-21. Review.


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