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Toxicity Related to Radiotherapy Dose and Targeting Strategy: A Pooled Analysis of Cooperative Group Trials of Combined Modality Therapy for Locally Advanced Non-Small Cell Lung Cancer.

Schild SE, Fan W, Stinchcombe TE, Vokes EE, Ramalingam SS, Bradley JD, Kelly K, Pang HH, Wang X.

J Thorac Oncol. 2018 Oct 4. pii: S1556-0864(18)33173-3. doi: 10.1016/j.jtho.2018.09.021. [Epub ahead of print]


Defining Optimal Comorbidity Measures for Patients With Early-Stage Non-Small Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy.

DeWees TA, Nikitas J, Rehman S, Bradley JD, Robinson CG, Roach MC.

Pract Radiat Oncol. 2018 Sep 20. pii: S1879-8500(18)30264-9. doi: 10.1016/j.prro.2018.09.001. [Epub ahead of print]


Optimizing radiation dose and fractionation for the definitive treatment of locally advanced non-small cell lung cancer.

Roach MC, Bradley JD, Robinson CG.

J Thorac Dis. 2018 Aug;10(Suppl 21):S2465-S2473. doi: 10.21037/jtd.2018.01.153. Review.


Magnetic Resonance Image-Guided Radiotherapy (MRIgRT): A 4.5-Year Clinical Experience.

Henke LE, Contreras JA, Green OL, Cai B, Kim H, Roach MC, Olsen JR, Fischer-Valuck B, Mullen DF, Kashani R, Thomas MA, Huang J, Zoberi I, Yang D, Rodriguez V, Bradley JD, Robinson CG, Parikh P, Mutic S, Michalski J.

Clin Oncol (R Coll Radiol). 2018 Nov;30(11):720-727. doi: 10.1016/j.clon.2018.08.010. Epub 2018 Sep 7.


Optically pumped rare-earth-doped Al2O3 distributed-feedback lasers on silicon [Invited].

Pollnau M, Bradley JDB.

Opt Express. 2018 Sep 3;26(18):24164-24189. doi: 10.1364/OE.26.024164.


Stereotactic Body Radiation Therapy for Central Early-Stage NSCLC: Results of a Prospective Phase I/II Trial.

Roach MC, Robinson CG, DeWees TA, Ganachaud J, Przybysz D, Drzymala R, Rehman S, Kashani R, Bradley JD.

J Thorac Oncol. 2018 Nov;13(11):1727-1732. doi: 10.1016/j.jtho.2018.07.017. Epub 2018 Jul 26.


In Silico Trial of MR-Guided Midtreatment Adaptive Planning for Hypofractionated Stereotactic Radiation Therapy in Centrally Located Thoracic Tumors.

Henke LE, Kashani R, Hilliard J, DeWees TA, Curcuru A, Przybysz D, Green O, Robinson CG, Bradley JD.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):987-995. doi: 10.1016/j.ijrobp.2018.06.022. Epub 2018 Jun 25.


Predictive biomarkers for response to EGFR-directed monoclonal antibodies for advanced squamous cell lung cancer.

Bonomi PD, Gandara D, Hirsch FR, Kerr KM, Obasaju C, Paz-Ares L, Bellomo C, Bradley JD, Bunn PA Jr, Culligan M, Jett JR, Kim ES, Langer CJ, Natale RB, Novello S, Pérol M, Ramalingam SS, Reck M, Reynolds CH, Smit EF, Socinski MA, Spigel DR, Vansteenkiste JF, Wakelee H, Thatcher N.

Ann Oncol. 2018 Aug 1;29(8):1701-1709. doi: 10.1093/annonc/mdy196.


Stereotactic Body Radiation Therapy for Operable Early-Stage Lung Cancer: Findings From the NRG Oncology RTOG 0618 Trial.

Timmerman RD, Paulus R, Pass HI, Gore EM, Edelman MJ, Galvin J, Straube WL, Nedzi LA, McGarry RC, Robinson CG, Schiff PB, Chang G, Loo BW Jr, Bradley JD, Choy H.

JAMA Oncol. 2018 Sep 1;4(9):1263-1266. doi: 10.1001/jamaoncol.2018.1251.


Molecular and Immune Biomarker Testing in Squamous-Cell Lung Cancer: Effect of Current and Future Therapies and Technologies.

Hirsch FR, Kerr KM, Bunn PA Jr, Kim ES, Obasaju C, Pérol M, Bonomi P, Bradley JD, Gandara D, Jett JR, Langer CJ, Natale RB, Novello S, Paz-Ares L, Ramalingam SS, Reck M, Reynolds CH, Smit EF, Socinski MA, Spigel DR, Stinchcombe TE, Vansteenkiste JF, Wakelee H, Thatcher N.

Clin Lung Cancer. 2018 Jul;19(4):331-339. doi: 10.1016/j.cllc.2018.03.014. Epub 2018 Mar 21. Review.


High-Q-factor Al2O3 micro-trench cavities integrated with silicon nitride waveguides on silicon.

Su Z, Li N, Frankis HC, Magden ES, Adam TN, Leake G, Coolbaugh D, Bradley JDB, Watts MR.

Opt Express. 2018 Apr 30;26(9):11161-11170. doi: 10.1364/OE.26.011161.


Exploring Radiotherapy Targeting Strategy and Dose: A Pooled Analysis of Cooperative Group Trials of Combined Modality Therapy for Stage III NSCLC.

Schild SE, Pang HH, Fan W, Stinchcombe TE, Vokes EE, Ramalingam SS, Bradley JD, Kelly K, Wang X.

J Thorac Oncol. 2018 Aug;13(8):1171-1182. doi: 10.1016/j.jtho.2018.04.011. Epub 2018 Apr 22.


Baricitinib in Patients with Rheumatoid Arthritis and an Inadequate Response to Conventional Disease-Modifying Antirheumatic Drugs in United States and Rest of World: A Subset Analysis.

Wells AF, Greenwald M, Bradley JD, Alam J, Arora V, Kartman CE.

Rheumatol Ther. 2018 Jun;5(1):43-55. doi: 10.1007/s40744-018-0110-x. Epub 2018 Apr 21.


Association of 1p/19q Codeletion and Radiation Necrosis in Adult Cranial Gliomas After Proton or Photon Therapy.

Acharya S, Robinson CG, Michalski JM, Mullen D, DeWees TA, Campian JL, Chundury A, Bottani B, Hallahan DE, Bradley JD, Huang J.

Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):334-343. doi: 10.1016/j.ijrobp.2018.01.099. Epub 2018 Feb 9.


Natural Disasters and the Importance of Minimizing Subsequent Radiation Therapy Interruptions for Locally Advanced Lung Cancer.

Roach MC, Robinson CG, Bradley JD.

Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):836-837. doi: 10.1016/j.ijrobp.2017.11.001. No abstract available.


Broadband 2-µm emission on silicon chips: monolithically integrated Holmium lasers.

Li N, Magden ES, Su Z, Singh N, Ruocco A, Xin M, Byrd M, Callahan PT, Bradley JDB, Baiocco C, Vermeulen D, Watts MR.

Opt Express. 2018 Feb 5;26(3):2220-2230. doi: 10.1364/OE.26.002220.


The Functional Immune Response of Patients on Extracorporeal Life Support.

Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK.

ASAIO J. 2018 Jan 10. doi: 10.1097/MAT.0000000000000748. [Epub ahead of print]


Optimal imaging surveillance after stereotactic ablative radiation therapy for early-stage non-small cell lung cancer: Findings of an International Delphi Consensus Study.

Nguyen TK, Senan S, Bradley JD, Franks K, Giuliani M, Guckenberger M, Landis M, Loo BW Jr, Louie AV, Onishi H, Schmidt H, Timmerman R, Videtic GMM, Palma DA.

Pract Radiat Oncol. 2018 Mar - Apr;8(2):e71-e78. doi: 10.1016/j.prro.2017.10.008. Epub 2017 Dec 30.


Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: a review of the National Cancer Database.

Vlacich G, Samson PP, Perkins SM, Roach MC, Parikh PJ, Bradley JD, Lockhart AC, Puri V, Meyers BF, Kozower B, Robinson CG.

Cancer Med. 2017 Dec;6(12):2886-2896. doi: 10.1002/cam4.1250. Epub 2017 Nov 15.


Two-and-a-half-year clinical experience with the world's first magnetic resonance image guided radiation therapy system.

Fischer-Valuck BW, Henke L, Green O, Kashani R, Acharya S, Bradley JD, Robinson CG, Thomas M, Zoberi I, Thorstad W, Gay H, Huang J, Roach M, Rodriguez V, Santanam L, Li H, Li H, Contreras J, Mazur T, Hallahan D, Olsen JR, Parikh P, Mutic S, Michalski J.

Adv Radiat Oncol. 2017 Jun 1;2(3):485-493. doi: 10.1016/j.adro.2017.05.006. eCollection 2017 Jul-Sep.


Concomitant Chemotherapy and Radiotherapy with SBRT Boost for Unresectable Stage III Non-Small Cell Lung Cancer: A Phase I Study.

Higgins KA, Pillai RN, Chen Z, Tian S, Zhang C, Patel P, Pakkala S, Shelton J, Force SD, Fernandez FG, Steuer CE, Owonikoko TK, Ramalingam SS, Bradley JD, Curran WJ.

J Thorac Oncol. 2017 Nov;12(11):1687-1695. doi: 10.1016/j.jtho.2017.07.036. Epub 2017 Sep 13.


Monolithically-integrated distributed feedback laser compatible with CMOS processing.

Magden ES, Li N, Purnawirman, Bradley JDB, Singh N, Ruocco A, Petrich GS, Leake G, Coolbaugh DD, Ippen EP, Watts MR, Kolodziejski LA.

Opt Express. 2017 Jul 24;25(15):18058-18065. doi: 10.1364/OE.25.018058.


Ultra-narrow-linewidth Al2O3:Er3+ lasers with a wavelength-insensitive waveguide design on a wafer-scale silicon nitride platform.

Purnawirman, Li N, Magden ES, Singh G, Singh N, Baldycheva A, Hosseini ES, Sun J, Moresco M, Adam TN, Leake G, Coolbaugh D, Bradley JDB, Watts MR.

Opt Express. 2017 Jun 12;25(12):13705-13713. doi: 10.1364/OE.25.013705.


Independent test of a model to predict severe acute esophagitis.

Huang EX, Robinson CG, Molotievschi A, Bradley JD, Deasy JO, Oh JH.

Adv Radiat Oncol. 2016 Nov 16;2(1):37-43. doi: 10.1016/j.adro.2016.11.003. eCollection 2017 Jan-Mar.


Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extracranial Irradiation for Extensive-Disease Small Cell Lung Cancer (ED SCLC): NRG Oncology RTOG 0937.

Gore EM, Hu C, Sun AY, Grimm DF, Ramalingam SS, Dunlap NE, Higgins KA, Werner-Wasik M, Allen AM, Iyengar P, Videtic GMM, Hales RK, McGarry RC, Urbanic JJ, Pu AT, Johnstone CA, Stieber VW, Paulus R, Bradley JD.

J Thorac Oncol. 2017 Oct;12(10):1561-1570. doi: 10.1016/j.jtho.2017.06.015. Epub 2017 Jun 23.


Randomized Phase II Study of Preoperative Chemoradiotherapy ± Panitumumab Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIa, N2+) Non-Small Cell Lung Cancer: NRG Oncology RTOG 0839.

Edelman MJ, Hu C, Le QT, Donington JS, D'Souza WD, Dicker AP, Loo BW, Gore EM, Videtic GMM, Evans NR, Leach JW, Diehn M, Feigenberg SJ, Chen Y, Paulus R, Bradley JD.

J Thorac Oncol. 2017 Sep;12(9):1413-1420. doi: 10.1016/j.jtho.2017.06.007. Epub 2017 Jun 16.


Athermal synchronization of laser source with WDM filter in a silicon photonics platform.

Li N, Su Z, Purnawirman, Salih Magden E, Poulton CV, Ruocco A, Singh N, Byrd MJ, Bradley JDB, Leake G, Watts MR.

Appl Phys Lett. 2017 May 22;110(21):211105. doi: 10.1063/1.4984022.


Modeling the Cellular Response of Lung Cancer to Radiation Therapy for a Broad Range of Fractionation Schedules.

Jeong J, Oh JH, Sonke JJ, Belderbos J, Bradley JD, Fontanella AN, Rao SS, Deasy JO.

Clin Cancer Res. 2017 Sep 15;23(18):5469-5479. doi: 10.1158/1078-0432.CCR-16-3277. Epub 2017 May 24.


Challenging Situations for Lung SBRT.

Przybysz D, Bradley JD.

J Thorac Oncol. 2017 Jun;12(6):916-918. doi: 10.1016/j.jtho.2017.04.007. No abstract available.


Pooled Analysis of Individual Patient Data on Concurrent Chemoradiotherapy for Stage III Non-Small-Cell Lung Cancer in Elderly Patients Compared With Younger Patients Who Participated in US National Cancer Institute Cooperative Group Studies.

Stinchcombe TE, Zhang Y, Vokes EE, Schiller JH, Bradley JD, Kelly K, Curran WJ Jr, Schild SE, Movsas B, Clamon G, Govindan R, Blumenschein GR, Socinski MA, Ready NE, Akerley WL, Cohen HJ, Pang HH, Wang X.

J Clin Oncol. 2017 Sep 1;35(25):2885-2892. doi: 10.1200/JCO.2016.71.4758. Epub 2017 May 11.


Wavelength division multiplexed light source monolithically integrated on a silicon photonics platform.

Purnawirman, Li N, Magden ES, Singh G, Moresco M, Adam TN, Leake G, Coolbaugh D, Bradley JDB, Watts MR.

Opt Lett. 2017 May 1;42(9):1772-1775. doi: 10.1364/OL.42.001772.


High-power thulium lasers on a silicon photonics platform.

Li N, Purnawirman P, Su Z, Salih Magden E, Callahan PT, Shtyrkova K, Xin M, Ruocco A, Baiocco C, Ippen EP, Kärtner FX, Bradley JD, Vermeulen D, Watts MR.

Opt Lett. 2017 Mar 15;42(6):1181-1184. doi: 10.1364/OL.42.001181.


Reply to D. Ball et al.

Chun SG, Hu C, Bradley JD.

J Clin Oncol. 2017 May 1;35(13):1493-1494. doi: 10.1200/JCO.2016.71.5755. Epub 2017 Jan 9. No abstract available.


Impact of Intensity-Modulated Radiation Therapy Technique for Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial.

Chun SG, Hu C, Choy H, Komaki RU, Timmerman RD, Schild SE, Bogart JA, Dobelbower MC, Bosch W, Galvin JM, Kavadi VS, Narayan S, Iyengar P, Robinson CG, Wynn RB, Raben A, Augspurger ME, MacRae RM, Paulus R, Bradley JD.

J Clin Oncol. 2017 Jan;35(1):56-62. Epub 2016 Oct 31.


Ultra-compact and low-threshold thulium microcavity laser monolithically integrated on silicon.

Su Z, Li N, Salih Magden E, Byrd M, Purnawirman P, Adam TN, Leake G, Coolbaugh D, Bradley JD, Watts MR.

Opt Lett. 2016 Dec 15;41(24):5708-5711. doi: 10.1364/OL.41.005708.


Optimal treatment of unresectable stage III non-small cell lung cancer.

Bradley JD.

Clin Adv Hematol Oncol. 2016 Nov;14(11):853-855. No abstract available.


Treatment Design and Rationale for a Randomized Trial of Cisplatin and Etoposide Plus Thoracic Radiotherapy Followed by Nivolumab or Placebo for Locally Advanced Non-Small-Cell Lung Cancer (RTOG 3505).

Gerber DE, Urbanic JJ, Langer C, Hu C, Chang IF, Lu B, Movsas B, Jeraj R, Curran WJ, Bradley JD.

Clin Lung Cancer. 2017 May;18(3):333-339. doi: 10.1016/j.cllc.2016.10.009. Epub 2016 Oct 26.


Heart Dose Is an Independent Dosimetric Predictor of Overall Survival in Locally Advanced Non-Small Cell Lung Cancer.

Speirs CK, DeWees TA, Rehman S, Molotievschi A, Velez MA, Mullen D, Fergus S, Trovo M, Bradley JD, Robinson CG.

J Thorac Oncol. 2017 Feb;12(2):293-301. doi: 10.1016/j.jtho.2016.09.134. Epub 2016 Oct 12.


Is radiographic progression in modern rheumatoid arthritis trials still a robust outcome? Experience from tofacitinib clinical trials.

Landewé RB, Connell CA, Bradley JD, Wilkinson B, Gruben D, Strengholt S, van der Heijde D.

Arthritis Res Ther. 2016 Sep 23;18(1):212.


Enrollment Trends and Disparity Among Patients With Lung Cancer in National Clinical Trials, 1990 to 2012.

Pang HH, Wang X, Stinchcombe TE, Wong ML, Cheng P, Ganti AK, Sargent DJ, Zhang Y, Hu C, Mandrekar SJ, Redman MW, Manola JB, Schilsky RL, Cohen HJ, Bradley JD, Adjei AA, Gandara D, Ramalingam SS, Vokes EE.

J Clin Oncol. 2016 Nov 20;34(33):3992-3999. doi: 10.1200/JCO.2016.67.7088. Epub 2016 Sep 30.


Meta-analysis of long-term joint structural deterioration in minimally treated patients with rheumatoid arthritis.

Jansen JP, Vieira MC, Bradley JD, Cappelleri JC, Zwillich SH, Wallenstein GV.

BMC Musculoskelet Disord. 2016 Aug 18;17(1):348. doi: 10.1186/s12891-016-1195-4.


Overview of Thoracic Oncology Trials in Cooperative Groups Around the Globe.

Salahudeen AA, Patel MI, Baas P, Curran WJ, Bradley JD, Gandara DR, Goss GD, Mok TS, Ramalingam SS, Vokes EE, Malik SM, Wakelee HA.

Clin Lung Cancer. 2017 Jan;18(1):5-12. doi: 10.1016/j.cllc.2016.06.007. Epub 2016 Jun 27. Review.


Institutional Enrollment and Survival Among NSCLC Patients Receiving Chemoradiation: NRG Oncology Radiation Therapy Oncology Group (RTOG) 0617.

Eaton BR, Pugh SL, Bradley JD, Masters G, Kavadi VS, Narayan S, Nedzi L, Robinson C, Wynn RB, Koprowski C, Johnson DW, Meng J, Curran WJ Jr.

J Natl Cancer Inst. 2016 May 19;108(9). pii: djw034. doi: 10.1093/jnci/djw034. Print 2016 Sep.


Establishing the feasibility of the dosimetric compliance criteria of RTOG 1308: phase III randomized trial comparing overall survival after photon versus proton radiochemotherapy for inoperable stage II-IIIB NSCLC.

Giaddui T, Chen W, Yu J, Lin L, Simone CB 2nd, Yuan L, Gong YU, Wu QJ, Mohan R, Zhang X, Bluett JB, Gillin M, Moore K, O'Meara E, Presley J, Bradley JD, Liao Z, Galvin J, Xiao Y.

Radiat Oncol. 2016 May 4;11:66. doi: 10.1186/s13014-016-0640-8.


Consensus Statement on Proton Therapy in Early-Stage and Locally Advanced Non-Small Cell Lung Cancer.

Chang JY, Jabbour SK, De Ruysscher D, Schild SE, Simone CB 2nd, Rengan R, Feigenberg S, Khan AJ, Choi NC, Bradley JD, Zhu XR, Lomax AJ, Hoppe BS; International Particle Therapy Co-operative Group Thoracic Subcommittee.

Int J Radiat Oncol Biol Phys. 2016 May 1;95(1):505-16. doi: 10.1016/j.ijrobp.2016.01.036. Epub 2016 Jan 23. Review.


Comparing the effects of tofacitinib, methotrexate and the combination, on bone marrow oedema, synovitis and bone erosion in methotrexate-naive, early active rheumatoid arthritis: results of an exploratory randomised MRI study incorporating semiquantitative and quantitative techniques.

Conaghan PG, Østergaard M, Bowes MA, Wu C, Fuerst T, van der Heijde D, Irazoque-Palazuelos F, Soto-Raices O, Hrycaj P, Xie Z, Zhang R, Wyman BT, Bradley JD, Soma K, Wilkinson B.

Ann Rheum Dis. 2016 Jun;75(6):1024-33. doi: 10.1136/annrheumdis-2015-208267. Epub 2016 Jan 25.


Resonant pumped erbium-doped waveguide lasers using distributed Bragg reflector cavities.

Singh G, Purnawirman P, Bradley JD, Li N, Magden ES, Moresco M, Adam TN, Leake G, Coolbaugh D, Watts MR.

Opt Lett. 2016 Mar 15;41(6):1189-92. doi: 10.1364/OL.41.001189.


Pretreatment 18F-FDG PET Textural Features in Locally Advanced Non-Small Cell Lung Cancer: Secondary Analysis of ACRIN 6668/RTOG 0235.

Ohri N, Duan F, Snyder BS, Wei B, Machtay M, Alavi A, Siegel BA, Johnson DW, Bradley JD, DeNittis A, Werner-Wasik M, El Naqa I.

J Nucl Med. 2016 Jun;57(6):842-8. doi: 10.2967/jnumed.115.166934. Epub 2016 Feb 11.


Factors Associated With Early Mortality in Patients Treated With Concurrent Chemoradiation Therapy for Locally Advanced Non-Small Cell Lung Cancer.

Warner A, Dahele M, Hu B, Palma DA, Senan S, Oberije C, Tsujino K, Moreno-Jimenez M, Kim TH, Marks LB, Rengan R, De Petris L, Ramella S, De Ruyck K, De Dios NR, Bradley JD, Rodrigues G.

Int J Radiat Oncol Biol Phys. 2016 Mar 1;94(3):612-20. doi: 10.1016/j.ijrobp.2015.11.030. Epub 2015 Nov 23. Erratum in: Int J Radiat Oncol Biol Phys. 2016 Jul 1;95(3):1087.


Imaging and Data Acquisition in Clinical Trials for Radiation Therapy.

FitzGerald TJ, Bishop-Jodoin M, Followill DS, Galvin J, Knopp MV, Michalski JM, Rosen MA, Bradley JD, Shankar LK, Laurie F, Cicchetti MG, Moni J, Coleman CN, Deye JA, Capala J, Vikram B.

Int J Radiat Oncol Biol Phys. 2016 Feb 1;94(2):404-11. doi: 10.1016/j.ijrobp.2015.10.028. Epub 2015 Oct 24. Review.

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