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Long-Term Results of NRG Oncology RTOG 0617: Standard- Versus High-Dose Chemoradiotherapy With or Without Cetuximab for Unresectable Stage III Non-Small-Cell Lung Cancer.

Bradley JD, Hu C, Komaki RR, Masters GA, Blumenschein GR, Schild SE, Bogart JA, Forster KM, Magliocco AM, Kavadi VS, Narayan S, Iyengar P, Robinson CG, Wynn RB, Koprowski CD, Olson MR, Meng J, Paulus R, Curran WJ Jr, Choy H.

J Clin Oncol. 2019 Dec 16:JCO1901162. doi: 10.1200/JCO.19.01162. [Epub ahead of print]


Thulium-doped tellurium oxide waveguide amplifier with 7.6  dB net gain on a silicon nitride chip.

Kiani KM, Frankis HC, Mbonde HM, Mateman R, Leinse A, Knights AP, Bradley JDB.

Opt Lett. 2019 Dec 1;44(23):5788-5791. doi: 10.1364/OL.44.005788.


Clinical outcomes and toxicity of proton beam radiation therapy for re-irradiation of locally recurrent breast cancer.

Gabani P, Patel H, Thomas MA, Bottani B, Goddu SM, Straube W, Margenthaler JA, Ochoa L, Bradley JD, Zoberi I.

Clin Transl Radiat Oncol. 2019 Oct 2;19:116-122. doi: 10.1016/j.ctro.2019.09.005. eCollection 2019 Nov.


Repeat stereotactic body radiation therapy (SBRT) for salvage of isolated local recurrence after definitive lung SBRT.

Kennedy WR, Gabani P, Nikitas J, Robinson CG, Bradley JD, Roach MC.

Radiother Oncol. 2019 Aug 31. pii: S0167-8140(19)33056-7. doi: 10.1016/j.radonc.2019.08.010. [Epub ahead of print]


Reply to T. Sio et al.

Bezjak A, Paulus R, Gaspar LE, Timmerman RD, Bradley JD.

J Clin Oncol. 2019 Oct 10;37(29):2699-2700. doi: 10.1200/JCO.19.01663. Epub 2019 Aug 29. No abstract available.


SWOG S1400D (NCT02965378), a Phase II Study of the Fibroblast Growth Factor Receptor Inhibitor AZD4547 in Previously Treated Patients With Fibroblast Growth Factor Pathway-Activated Stage IV Squamous Cell Lung Cancer (Lung-MAP Substudy).

Aggarwal C, Redman MW, Lara PN Jr, Borghaei H, Hoffman P, Bradley JD, Newman AJ 3rd, Feldman MJ, Minichiello K, Miao J, Mack PC, Papadimitrakopoulou VA, Herbst RS, Kelly K, Gandara DR.

J Thorac Oncol. 2019 Oct;14(10):1847-1852. doi: 10.1016/j.jtho.2019.05.041. Epub 2019 Jun 11.


Radiation Toxicity in Lung Cancer Patients: The Heart of the Problem?

Badiyan SN, Robinson CG, Bradley JD.

Int J Radiat Oncol Biol Phys. 2019 Jul 1;104(3):590-592. doi: 10.1016/j.ijrobp.2019.03.007. No abstract available.


SWOG S1400B (NCT02785913), a Phase II Study of GDC-0032 (Taselisib) for Previously Treated PI3K-Positive Patients with Stage IV Squamous Cell Lung Cancer (Lung-MAP Sub-Study).

Langer CJ, Redman MW, Wade JL 3rd, Aggarwal C, Bradley JD, Crawford J, Stella PJ, Knapp MH, Miao J, Minichiello K, Herbst RS, Kelly K, Gandara DR, Papadimitrakopoulou VA.

J Thorac Oncol. 2019 Oct;14(10):1839-1846. doi: 10.1016/j.jtho.2019.05.029. Epub 2019 May 31.


Low-loss TeO2-coated Si3N4 waveguides for application in photonic integrated circuits.

Frankis HC, Kiani KM, Bonneville DB, Zhang C, Norris S, Mateman R, Leinse A, Bassim ND, Knights AP, Bradley JDB.

Opt Express. 2019 Apr 29;27(9):12529-12540. doi: 10.1364/OE.27.012529.


Safety and Efficacy of a Five-Fraction Stereotactic Body Radiotherapy Schedule for Centrally Located Non-Small-Cell Lung Cancer: NRG Oncology/RTOG 0813 Trial.

Bezjak A, Paulus R, Gaspar LE, Timmerman RD, Straube WL, Ryan WF, Garces YI, Pu AT, Singh AK, Videtic GM, McGarry RC, Iyengar P, Pantarotto JR, Urbanic JJ, Sun AY, Daly ME, Grills IS, Sperduto P, Normolle DP, Bradley JD, Choy H.

J Clin Oncol. 2019 May 20;37(15):1316-1325. doi: 10.1200/JCO.18.00622. Epub 2019 Apr 3.


Treatment of T3N0 non-small cell lung cancer with chest wall invasion using stereotactic body radiotherapy.

Kennedy WR, Gabani P, Nikitas J, Samson PP, Robinson CG, Bradley JD, Roach MC.

Clin Transl Radiat Oncol. 2019 Feb 21;16:1-6. doi: 10.1016/j.ctro.2019.02.004. eCollection 2019 May.


Stereotactic MR-Guided Online Adaptive Radiation Therapy (SMART) for Ultracentral Thorax Malignancies: Results of a Phase 1 Trial.

Henke LE, Olsen JR, Contreras JA, Curcuru A, DeWees TA, Green OL, Michalski J, Mutic S, Roach MC, Bradley JD, Parikh PJ, Kashani R, Robinson CG.

Adv Radiat Oncol. 2018 Oct 18;4(1):201-209. doi: 10.1016/j.adro.2018.10.003. eCollection 2019 Jan-Mar.


High-Q tellurium-oxide-coated silicon nitride microring resonators.

Frankis HC, Kiani KM, Su D, Mateman R, Leinse A, Bradley JDB.

Opt Lett. 2019 Jan 1;44(1):118-121. doi: 10.1364/OL.44.000118.


Multi-Institutional Validation of a Knowledge-Based Planning Model for Patients Enrolled in RTOG 0617: Implications for Plan Quality Controls in Cooperative Group Trials.

Kavanaugh JA, Holler S, DeWees TA, Robinson CG, Bradley JD, Iyengar P, Higgins KA, Mutic S, Olsen LA.

Pract Radiat Oncol. 2019 Mar;9(2):e218-e227. doi: 10.1016/j.prro.2018.11.007. Epub 2018 Dec 15.


Long-term Follow-up on NRG Oncology RTOG 0915 (NCCTG N0927): A Randomized Phase 2 Study Comparing 2 Stereotactic Body Radiation Therapy Schedules for Medically Inoperable Patients With Stage I Peripheral Non-Small Cell Lung Cancer.

Videtic GM, Paulus R, Singh AK, Chang JY, Parker W, Olivier KR, Timmerman RD, Komaki RR, Urbanic JJ, Stephans KL, Yom SS, Robinson CG, Belani CP, Iyengar P, Ajlouni MI, Gopaul DD, Gomez Suescun JB, McGarry RC, Choy H, Bradley JD.

Int J Radiat Oncol Biol Phys. 2019 Apr 1;103(5):1077-1084. doi: 10.1016/j.ijrobp.2018.11.051. Epub 2018 Dec 1.


A Tellurium Oxide Microcavity Resonator Sensor Integrated On-Chip with a Silicon Waveguide.

Frankis HC, Su D, Bonneville DB, Bradley JDB.

Sensors (Basel). 2018 Nov 21;18(11). pii: E4061. doi: 10.3390/s18114061.


Induction Radiation Therapy for Esophageal Cancer: Does Dose Affect Outcomes?

Semenkovich TR, Samson PP, Hudson JL, Subramanian M, Meyers BF, Kozower BD, Kreisel D, Patterson GA, Robinson CG, Bradley JD, Puri V.

Ann Thorac Surg. 2019 Mar;107(3):903-911. doi: 10.1016/j.athoracsur.2018.09.064. Epub 2018 Nov 13.


Toxicity Related to Radiotherapy Dose and Targeting Strategy: A Pooled Analysis of Cooperative Group Trials of Combined Modality Therapy for Locally Advanced Non-Small Cell Lung Cancer.

Schild SE, Fan W, Stinchcombe TE, Vokes EE, Ramalingam SS, Bradley JD, Kelly K, Pang HH, Wang X.

J Thorac Oncol. 2019 Feb;14(2):298-303. doi: 10.1016/j.jtho.2018.09.021. Epub 2018 Oct 4.


Defining Optimal Comorbidity Measures for Patients With Early-Stage Non-small cell lung cancer Treated With Stereotactic Body Radiation Therapy.

DeWees TA, Nikitas J, Rehman S, Bradley JD, Robinson CG, Roach MC.

Pract Radiat Oncol. 2019 Jan;9(1):e83-e89. doi: 10.1016/j.prro.2018.09.001. Epub 2018 Sep 20.


Optimizing radiation dose and fractionation for the definitive treatment of locally advanced non-small cell lung cancer.

Roach MC, Bradley JD, Robinson CG.

J Thorac Dis. 2018 Aug;10(Suppl 21):S2465-S2473. doi: 10.21037/jtd.2018.01.153. Review.


Magnetic Resonance Image-Guided Radiotherapy (MRIgRT): A 4.5-Year Clinical Experience.

Henke LE, Contreras JA, Green OL, Cai B, Kim H, Roach MC, Olsen JR, Fischer-Valuck B, Mullen DF, Kashani R, Thomas MA, Huang J, Zoberi I, Yang D, Rodriguez V, Bradley JD, Robinson CG, Parikh P, Mutic S, Michalski J.

Clin Oncol (R Coll Radiol). 2018 Nov;30(11):720-727. doi: 10.1016/j.clon.2018.08.010. Epub 2018 Sep 7.


Optically pumped rare-earth-doped Al2O3 distributed-feedback lasers on silicon [Invited].

Pollnau M, Bradley JDB.

Opt Express. 2018 Sep 3;26(18):24164-24189. doi: 10.1364/OE.26.024164.


Stereotactic Body Radiation Therapy for Central Early-Stage NSCLC: Results of a Prospective Phase I/II Trial.

Roach MC, Robinson CG, DeWees TA, Ganachaud J, Przybysz D, Drzymala R, Rehman S, Kashani R, Bradley JD.

J Thorac Oncol. 2018 Nov;13(11):1727-1732. doi: 10.1016/j.jtho.2018.07.017. Epub 2018 Jul 26.


In Silico Trial of MR-Guided Midtreatment Adaptive Planning for Hypofractionated Stereotactic Radiation Therapy in Centrally Located Thoracic Tumors.

Henke LE, Kashani R, Hilliard J, DeWees TA, Curcuru A, Przybysz D, Green O, Robinson CG, Bradley JD.

Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):987-995. doi: 10.1016/j.ijrobp.2018.06.022. Epub 2018 Jun 25.


Predictive biomarkers for response to EGFR-directed monoclonal antibodies for advanced squamous cell lung cancer.

Bonomi PD, Gandara D, Hirsch FR, Kerr KM, Obasaju C, Paz-Ares L, Bellomo C, Bradley JD, Bunn PA Jr, Culligan M, Jett JR, Kim ES, Langer CJ, Natale RB, Novello S, Pérol M, Ramalingam SS, Reck M, Reynolds CH, Smit EF, Socinski MA, Spigel DR, Vansteenkiste JF, Wakelee H, Thatcher N.

Ann Oncol. 2018 Aug 1;29(8):1701-1709. doi: 10.1093/annonc/mdy196. Review.


Stereotactic Body Radiation Therapy for Operable Early-Stage Lung Cancer: Findings From the NRG Oncology RTOG 0618 Trial.

Timmerman RD, Paulus R, Pass HI, Gore EM, Edelman MJ, Galvin J, Straube WL, Nedzi LA, McGarry RC, Robinson CG, Schiff PB, Chang G, Loo BW Jr, Bradley JD, Choy H.

JAMA Oncol. 2018 Sep 1;4(9):1263-1266. doi: 10.1001/jamaoncol.2018.1251.


Molecular and Immune Biomarker Testing in Squamous-Cell Lung Cancer: Effect of Current and Future Therapies and Technologies.

Hirsch FR, Kerr KM, Bunn PA Jr, Kim ES, Obasaju C, Pérol M, Bonomi P, Bradley JD, Gandara D, Jett JR, Langer CJ, Natale RB, Novello S, Paz-Ares L, Ramalingam SS, Reck M, Reynolds CH, Smit EF, Socinski MA, Spigel DR, Stinchcombe TE, Vansteenkiste JF, Wakelee H, Thatcher N.

Clin Lung Cancer. 2018 Jul;19(4):331-339. doi: 10.1016/j.cllc.2018.03.014. Epub 2018 Mar 21. Review.


High-Q-factor Al2O3 micro-trench cavities integrated with silicon nitride waveguides on silicon.

Su Z, Li N, Frankis HC, Magden ES, Adam TN, Leake G, Coolbaugh D, Bradley JDB, Watts MR.

Opt Express. 2018 Apr 30;26(9):11161-11170. doi: 10.1364/OE.26.011161.


Exploring Radiotherapy Targeting Strategy and Dose: A Pooled Analysis of Cooperative Group Trials of Combined Modality Therapy for Stage III NSCLC.

Schild SE, Pang HH, Fan W, Stinchcombe TE, Vokes EE, Ramalingam SS, Bradley JD, Kelly K, Wang X.

J Thorac Oncol. 2018 Aug;13(8):1171-1182. doi: 10.1016/j.jtho.2018.04.011. Epub 2018 Apr 22.


Baricitinib in Patients with Rheumatoid Arthritis and an Inadequate Response to Conventional Disease-Modifying Antirheumatic Drugs in United States and Rest of World: A Subset Analysis.

Wells AF, Greenwald M, Bradley JD, Alam J, Arora V, Kartman CE.

Rheumatol Ther. 2018 Jun;5(1):43-55. doi: 10.1007/s40744-018-0110-x. Epub 2018 Apr 21.


Association of 1p/19q Codeletion and Radiation Necrosis in Adult Cranial Gliomas After Proton or Photon Therapy.

Acharya S, Robinson CG, Michalski JM, Mullen D, DeWees TA, Campian JL, Chundury A, Bottani B, Hallahan DE, Bradley JD, Huang J.

Int J Radiat Oncol Biol Phys. 2018 Jun 1;101(2):334-343. doi: 10.1016/j.ijrobp.2018.01.099. Epub 2018 Feb 9.


Natural Disasters and the Importance of Minimizing Subsequent Radiation Therapy Interruptions for Locally Advanced Lung Cancer.

Roach MC, Robinson CG, Bradley JD.

Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):836-837. doi: 10.1016/j.ijrobp.2017.11.001. No abstract available.


Broadband 2-µm emission on silicon chips: monolithically integrated Holmium lasers.

Li N, Magden ES, Su Z, Singh N, Ruocco A, Xin M, Byrd M, Callahan PT, Bradley JDB, Baiocco C, Vermeulen D, Watts MR.

Opt Express. 2018 Feb 5;26(3):2220-2230. doi: 10.1364/OE.26.002220.


The Functional Immune Response of Patients on Extracorporeal Life Support.

Beshish AG, Bradley JD, McDonough KL, Halligan NLN, McHugh WM, Sturza J, Hall MW, Cornell TT, Dahmer MK.

ASAIO J. 2019 Jan;65(1):77-83. doi: 10.1097/MAT.0000000000000748.


Optimal imaging surveillance after stereotactic ablative radiation therapy for early-stage non-small cell lung cancer: Findings of an International Delphi Consensus Study.

Nguyen TK, Senan S, Bradley JD, Franks K, Giuliani M, Guckenberger M, Landis M, Loo BW Jr, Louie AV, Onishi H, Schmidt H, Timmerman R, Videtic GMM, Palma DA.

Pract Radiat Oncol. 2018 Mar - Apr;8(2):e71-e78. doi: 10.1016/j.prro.2017.10.008. Epub 2017 Dec 30.


Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: a review of the National Cancer Database.

Vlacich G, Samson PP, Perkins SM, Roach MC, Parikh PJ, Bradley JD, Lockhart AC, Puri V, Meyers BF, Kozower B, Robinson CG.

Cancer Med. 2017 Dec;6(12):2886-2896. doi: 10.1002/cam4.1250. Epub 2017 Nov 15.


Two-and-a-half-year clinical experience with the world's first magnetic resonance image guided radiation therapy system.

Fischer-Valuck BW, Henke L, Green O, Kashani R, Acharya S, Bradley JD, Robinson CG, Thomas M, Zoberi I, Thorstad W, Gay H, Huang J, Roach M, Rodriguez V, Santanam L, Li H, Li H, Contreras J, Mazur T, Hallahan D, Olsen JR, Parikh P, Mutic S, Michalski J.

Adv Radiat Oncol. 2017 Jun 1;2(3):485-493. doi: 10.1016/j.adro.2017.05.006. eCollection 2017 Jul-Sep.


Concomitant Chemotherapy and Radiotherapy with SBRT Boost for Unresectable Stage III Non-Small Cell Lung Cancer: A Phase I Study.

Higgins KA, Pillai RN, Chen Z, Tian S, Zhang C, Patel P, Pakkala S, Shelton J, Force SD, Fernandez FG, Steuer CE, Owonikoko TK, Ramalingam SS, Bradley JD, Curran WJ.

J Thorac Oncol. 2017 Nov;12(11):1687-1695. doi: 10.1016/j.jtho.2017.07.036. Epub 2017 Sep 13.


Monolithically-integrated distributed feedback laser compatible with CMOS processing.

Magden ES, Li N, Purnawirman, Bradley JDB, Singh N, Ruocco A, Petrich GS, Leake G, Coolbaugh DD, Ippen EP, Watts MR, Kolodziejski LA.

Opt Express. 2017 Jul 24;25(15):18058-18065. doi: 10.1364/OE.25.018058.


Ultra-narrow-linewidth Al2O3:Er3+ lasers with a wavelength-insensitive waveguide design on a wafer-scale silicon nitride platform.

Purnawirman, Li N, Magden ES, Singh G, Singh N, Baldycheva A, Hosseini ES, Sun J, Moresco M, Adam TN, Leake G, Coolbaugh D, Bradley JDB, Watts MR.

Opt Express. 2017 Jun 12;25(12):13705-13713. doi: 10.1364/OE.25.013705.


Independent test of a model to predict severe acute esophagitis.

Huang EX, Robinson CG, Molotievschi A, Bradley JD, Deasy JO, Oh JH.

Adv Radiat Oncol. 2016 Nov 16;2(1):37-43. doi: 10.1016/j.adro.2016.11.003. eCollection 2017 Jan-Mar.


Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extracranial Irradiation for Extensive-Disease Small Cell Lung Cancer (ED SCLC): NRG Oncology RTOG 0937.

Gore EM, Hu C, Sun AY, Grimm DF, Ramalingam SS, Dunlap NE, Higgins KA, Werner-Wasik M, Allen AM, Iyengar P, Videtic GMM, Hales RK, McGarry RC, Urbanic JJ, Pu AT, Johnstone CA, Stieber VW, Paulus R, Bradley JD.

J Thorac Oncol. 2017 Oct;12(10):1561-1570. doi: 10.1016/j.jtho.2017.06.015. Epub 2017 Jun 23.


Randomized Phase II Study of Preoperative Chemoradiotherapy ± Panitumumab Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced (Stage IIIa, N2+) Non-Small Cell Lung Cancer: NRG Oncology RTOG 0839.

Edelman MJ, Hu C, Le QT, Donington JS, D'Souza WD, Dicker AP, Loo BW, Gore EM, Videtic GMM, Evans NR, Leach JW, Diehn M, Feigenberg SJ, Chen Y, Paulus R, Bradley JD.

J Thorac Oncol. 2017 Sep;12(9):1413-1420. doi: 10.1016/j.jtho.2017.06.007. Epub 2017 Jun 16.


Athermal synchronization of laser source with WDM filter in a silicon photonics platform.

Li N, Su Z, Purnawirman, Salih Magden E, Poulton CV, Ruocco A, Singh N, Byrd MJ, Bradley JDB, Leake G, Watts MR.

Appl Phys Lett. 2017 May 22;110(21):211105. doi: 10.1063/1.4984022.


Modeling the Cellular Response of Lung Cancer to Radiation Therapy for a Broad Range of Fractionation Schedules.

Jeong J, Oh JH, Sonke JJ, Belderbos J, Bradley JD, Fontanella AN, Rao SS, Deasy JO.

Clin Cancer Res. 2017 Sep 15;23(18):5469-5479. doi: 10.1158/1078-0432.CCR-16-3277. Epub 2017 May 24.


Challenging Situations for Lung SBRT.

Przybysz D, Bradley JD.

J Thorac Oncol. 2017 Jun;12(6):916-918. doi: 10.1016/j.jtho.2017.04.007. No abstract available.


Pooled Analysis of Individual Patient Data on Concurrent Chemoradiotherapy for Stage III Non-Small-Cell Lung Cancer in Elderly Patients Compared With Younger Patients Who Participated in US National Cancer Institute Cooperative Group Studies.

Stinchcombe TE, Zhang Y, Vokes EE, Schiller JH, Bradley JD, Kelly K, Curran WJ Jr, Schild SE, Movsas B, Clamon G, Govindan R, Blumenschein GR, Socinski MA, Ready NE, Akerley WL, Cohen HJ, Pang HH, Wang X.

J Clin Oncol. 2017 Sep 1;35(25):2885-2892. doi: 10.1200/JCO.2016.71.4758. Epub 2017 May 11.


Wavelength division multiplexed light source monolithically integrated on a silicon photonics platform.

Purnawirman, Li N, Magden ES, Singh G, Moresco M, Adam TN, Leake G, Coolbaugh D, Bradley JDB, Watts MR.

Opt Lett. 2017 May 1;42(9):1772-1775. doi: 10.1364/OL.42.001772.


High-power thulium lasers on a silicon photonics platform.

Li N, Purnawirman P, Su Z, Salih Magden E, Callahan PT, Shtyrkova K, Xin M, Ruocco A, Baiocco C, Ippen EP, Kärtner FX, Bradley JD, Vermeulen D, Watts MR.

Opt Lett. 2017 Mar 15;42(6):1181-1184. doi: 10.1364/OL.42.001181.


Reply to D. Ball et al.

Chun SG, Hu C, Bradley JD.

J Clin Oncol. 2017 May 1;35(13):1493-1494. doi: 10.1200/JCO.2016.71.5755. Epub 2017 Jan 9. No abstract available.


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