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Items: 1 to 50 of 147

1.

Improved detection of blood stream pathogens by real-time PCR in severe sepsis.

Lehmann LE, Hunfeld KP, Steinbrucker M, Brade V, Book M, Seifert H, Bingold T, Hoeft A, Wissing H, Stüber F.

Intensive Care Med. 2010 Jan;36(1):49-56. doi: 10.1007/s00134-009-1608-z. Epub 2009 Sep 15.

2.

Mutational analyses of the BbCRASP-1 protein of Borrelia burgdorferi identify residues relevant for the architecture and binding of host complement regulators FHL-1 and factor H.

Kraiczy P, Hanssen-Hübner C, Kitiratschky V, Brenner C, Besier S, Brade V, Simon MM, Skerka C, Roversi P, Lea SM, Stevenson B, Wallich R, Zipfel PF.

Int J Med Microbiol. 2009 Apr;299(4):255-68. doi: 10.1016/j.ijmm.2008.09.002. Epub 2009 Jan 9.

PMID:
19138559
3.

Thymidine-dependent Staphylococcus aureus small-colony variants: human pathogens that are relevant not only in cases of cystic fibrosis lung disease.

Besier S, Zander J, Siegel E, Saum SH, Hunfeld KP, Ehrhart A, Brade V, Wichelhaus TA.

J Clin Microbiol. 2008 Nov;46(11):3829-32. doi: 10.1128/JCM.01440-08. Epub 2008 Oct 1.

4.

Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1.

Siegel C, Schreiber J, Haupt K, Skerka C, Brade V, Simon MM, Stevenson B, Wallich R, Zipfel PF, Kraiczy P.

J Biol Chem. 2008 Dec 12;283(50):34855-63. doi: 10.1074/jbc.M805844200. Epub 2008 Sep 29.

5.

Identification and characterization of the factor H and FHL-1 binding complement regulator-acquiring surface protein 1 of the Lyme disease spirochete Borrelia spielmanii sp. nov.

Herzberger P, Siegel C, Skerka C, Fingerle V, Schulte-Spechtel U, Wilske B, Brade V, Zipfel PF, Wallich R, Kraiczy P.

Int J Med Microbiol. 2009 Feb;299(2):141-54. doi: 10.1016/j.ijmm.2008.06.005. Epub 2008 Aug 15.

PMID:
18706858
6.

Systematic analysis highlights the key role of TLR2/NF-kappaB/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates.

Sadik CD, Hunfeld KP, Bachmann M, Kraiczy P, Eberhardt W, Brade V, Pfeilschifter J, Mühl H.

Int J Biochem Cell Biol. 2008;40(11):2508-21. doi: 10.1016/j.biocel.2008.04.014. Epub 2008 May 16.

PMID:
18571457
7.

The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates.

Besier S, Zander J, Kahl BC, Kraiczy P, Brade V, Wichelhaus TA.

Antimicrob Agents Chemother. 2008 Jun;52(6):2183-9. doi: 10.1128/AAC.01395-07. Epub 2008 Mar 31.

8.

[Molecular biological detection of pathogens in patients with sepsis. Potentials, limitations and perspectives].

Hunfeld KP, Bingold T, Brade V, Wissing H.

Anaesthesist. 2008 Apr;57(4):326-37. doi: 10.1007/s00101-008-1345-7. Review. German.

PMID:
18351304
9.

Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances.

Besier S, Ludwig A, Zander J, Brade V, Wichelhaus TA.

Antimicrob Agents Chemother. 2008 Apr;52(4):1570-2. doi: 10.1128/AAC.01098-07. Epub 2008 Jan 22.

10.

Borrelia burgdorferi complement regulator-acquiring surface proteins (BbCRASPs): Expression patterns during the mammal-tick infection cycle.

Bykowski T, Woodman ME, Cooley AE, Brissette CA, Wallich R, Brade V, Kraiczy P, Stevenson B.

Int J Med Microbiol. 2008 Sep 1;298 Suppl 1:249-56. doi: 10.1016/j.ijmm.2007.10.002. Epub 2007 Dec 31. Review.

11.

Borrelia burgdorferi complement regulator-acquiring surface protein 2 (CspZ) as a serological marker of human Lyme disease.

Kraiczy P, Seling A, Brissette CA, Rossmann E, Hunfeld KP, Bykowski T, Burns LH, Troese MJ, Cooley AE, Miller JC, Brade V, Wallich R, Casjens S, Stevenson B.

Clin Vaccine Immunol. 2008 Mar;15(3):484-91. Epub 2007 Dec 26.

12.

Influence of dTMP on the phenotypic appearance and intracellular persistence of Staphylococcus aureus.

Zander J, Besier S, Saum SH, Dehghani F, Loitsch S, Brade V, Wichelhaus TA.

Infect Immun. 2008 Apr;76(4):1333-9. Epub 2007 Dec 26.

13.

Release of latent ClyA cytolysin from Escherichia coli mediated by a bacteriophage-associated putative holin (BlyA) from Borrelia burgdorferi.

Ludwig A, von Rhein C, Mischke A, Brade V.

Int J Med Microbiol. 2008 Jul;298(5-6):473-81. Epub 2007 Sep 25.

PMID:
17897882
14.

Human pathogenic Borrelia spielmanii sp. nov. resists complement-mediated killing by direct binding of immune regulators factor H and factor H-like protein 1.

Herzberger P, Siegel C, Skerka C, Fingerle V, Schulte-Spechtel U, van Dam A, Wilske B, Brade V, Zipfel PF, Wallich R, Kraiczy P.

Infect Immun. 2007 Oct;75(10):4817-25. Epub 2007 Jul 16.

15.

Coordinated expression of Borrelia burgdorferi complement regulator-acquiring surface proteins during the Lyme disease spirochete's mammal-tick infection cycle.

Bykowski T, Woodman ME, Cooley AE, Brissette CA, Brade V, Wallich R, Kraiczy P, Stevenson B.

Infect Immun. 2007 Sep;75(9):4227-36. Epub 2007 Jun 11.

16.

Binding of human factor H-related protein 1 to serum-resistant Borrelia burgdorferi is mediated by borrelial complement regulator-acquiring surface proteins.

Haupt K, Kraiczy P, Wallich R, Brade V, Skerka C, Zipfel PF.

J Infect Dis. 2007 Jul 1;196(1):124-33. Epub 2007 May 23.

PMID:
17538892
17.

[Subcutaneous emphysema of unusual extent].

Besier S, Bingold TM, Walcher F, Engels K, Spellerberg B, Brade V, Brandt C.

Chirurg. 2007 Dec;78(12):1148-51. German.

PMID:
17431554
18.

Molecular analysis of the thymidine-auxotrophic small colony variant phenotype of Staphylococcus aureus.

Besier S, Ludwig A, Ohlsen K, Brade V, Wichelhaus TA.

Int J Med Microbiol. 2007 Jul;297(4):217-25. Epub 2007 Apr 6.

PMID:
17412637
19.

First case of human babesiosis in Germany - Clinical presentation and molecular characterisation of the pathogen.

Häselbarth K, Tenter AM, Brade V, Krieger G, Hunfeld KP.

Int J Med Microbiol. 2007 Jun;297(3):197-204. Epub 2007 Mar 12.

PMID:
17350888
20.

Leprosy in a pregnant woman.

Böddinghaus BK, Ludwig RJ, Kaufmann R, Enzensberger R, Gies V, Kramme S, Brade V, Brandt CM.

Infection. 2007 Feb;35(1):37-9.

PMID:
17297589
21.

Binding of human complement regulators FHL-1 and factor H to CRASP-1 orthologs of Borrelia burgdorferi.

Kraiczy P, Rossmann E, Brade V, Simon MM, Skerka C, Zipfel PF, Wallich R.

Wien Klin Wochenschr. 2006 Nov;118(21-22):669-76.

PMID:
17160605
22.
23.

Prevalence and clinical significance of Staphylococcus aureus small-colony variants in cystic fibrosis lung disease.

Besier S, Smaczny C, von Mallinckrodt C, Krahl A, Ackermann H, Brade V, Wichelhaus TA.

J Clin Microbiol. 2007 Jan;45(1):168-72. Epub 2006 Nov 15.

24.

Functional characterization of BbCRASP-2, a distinct outer membrane protein of Borrelia burgdorferi that binds host complement regulators factor H and FHL-1.

Hartmann K, Corvey C, Skerka C, Kirschfink M, Karas M, Brade V, Miller JC, Stevenson B, Wallich R, Zipfel PF, Kraiczy P.

Mol Microbiol. 2006 Sep;61(5):1220-36.

25.
26.

Structure-function mapping of BbCRASP-1, the key complement factor H and FHL-1 binding protein of Borrelia burgdorferi.

Cordes FS, Kraiczy P, Roversi P, Simon MM, Brade V, Jahraus O, Wallis R, Goodstadt L, Ponting CP, Skerka C, Zipfel PF, Wallich R, Lea SM.

Int J Med Microbiol. 2006 May;296 Suppl 40:177-84. Epub 2006 Mar 10.

PMID:
16530476
27.

Borrelia burgdorferi regulates expression of complement regulator-acquiring surface protein 1 during the mammal-tick infection cycle.

von Lackum K, Miller JC, Bykowski T, Riley SP, Woodman ME, Brade V, Kraiczy P, Stevenson B, Wallich R.

Infect Immun. 2005 Nov;73(11):7398-405.

28.

[Spontaneous gas gangrene in a diabetic patient with Clostridium septicum].

Mischke A, Besier S, Walcher F, Waibel H, Brade V, Brandt C.

Chirurg. 2005 Oct;76(10):983-6. German.

PMID:
16021394
29.
30.

Identification and functional characterization of complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes Borrelia afzelii and Borrelia garinii.

Wallich R, Pattathu J, Kitiratschky V, Brenner C, Zipfel PF, Brade V, Simon MM, Kraiczy P.

Infect Immun. 2005 Apr;73(4):2351-9.

31.
32.

A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi.

Cordes FS, Roversi P, Kraiczy P, Simon MM, Brade V, Jahraus O, Wallis R, Skerka C, Zipfel PF, Wallich R, Lea SM.

Nat Struct Mol Biol. 2005 Mar;12(3):276-7. Epub 2005 Feb 13.

PMID:
15711564
33.

New real-time PCR-based method for in vitro susceptibility testing of Anaplasma phagocytophilum against antimicrobial agents.

Hunfeld KP, Bittner T, Rödel R, Brade V, Cinatl J.

Int J Antimicrob Agents. 2004 Jun;23(6):563-71.

PMID:
15194126
34.

Immunological characterization of the complement regulator factor H-binding CRASP and Erp proteins of Borrelia burgdorferi.

Kraiczy P, Hartmann K, Hellwage J, Skerka C, Kirschfink M, Brade V, Zipfel PF, Wallich R, Stevenson B.

Int J Med Microbiol. 2004 Apr;293 Suppl 37:152-7.

PMID:
15146998
35.

Zoonotic Babesia: possibly emerging pathogens to be considered for tick-infested humans in Central Europe.

Hunfeld KP, Brade V.

Int J Med Microbiol. 2004 Apr;293 Suppl 37:93-103. Review.

PMID:
15146990
36.

Crystallization and preliminary crystallographic analysis of BbCRASP-1, a complement regulator-acquiring surface protein of Borrelia burgdorferi.

Cordes FS, Kraiczy P, Roversi P, Skerka C, Kirschfink M, Simon MM, Brade V, Lowe ED, Zipfel P, Wallich R, Lea SM.

Acta Crystallogr D Biol Crystallogr. 2004 May;60(Pt 5):929-32. Epub 2004 Apr 21.

PMID:
15103142
37.

Streptococcus pyogenes meningitis complicating varicella in a 3-month-old child.

Brandt CM, Kitz R, Lütticken R, Brade V.

Scand J Infect Dis. 2003;35(11-12):876-8.

PMID:
14723366
38.

Comparison of in vitro activities of ketolides, macrolides, and an azalide against the spirochete Borrelia burgdorferi.

Hunfeld KP, Wichelhaus TA, Rödel R, Acker G, Brade V, Kraiczy P.

Antimicrob Agents Chemother. 2004 Jan;48(1):344-7.

39.

Complement resistance of Borrelia burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins.

Kraiczy P, Hellwage J, Skerka C, Becker H, Kirschfink M, Simon MM, Brade V, Zipfel PF, Wallich R.

J Biol Chem. 2004 Jan 23;279(4):2421-9. Epub 2003 Nov 7.

40.

Selection of ketolide resistance in Staphylococcus aureus.

Besier S, Hunfeld KP, Giesser I, Schäfer V, Brade V, Wichelhaus TA.

Int J Antimicrob Agents. 2003 Jul;22(1):87-8. No abstract available.

PMID:
12842336
41.

Immune evasion of Borrelia burgdorferi: mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family.

Kraiczy P, Hellwage J, Skerka C, Kirschfink M, Brade V, Zipfel PF, Wallich R.

Eur J Immunol. 2003 Mar;33(3):697-707.

42.

Molecular analysis of fusidic acid resistance in Staphylococcus aureus.

Besier S, Ludwig A, Brade V, Wichelhaus TA.

Mol Microbiol. 2003 Jan;47(2):463-9.

43.

Disseminated cutaneous Mycobacterium marinum infection in a patient with non-Hodgkin's lymphoma.

Enzensberger R, Hunfeld KP, Elshorst-Schmidt T, Böer A, Brade V.

Infection. 2002 Dec;30(6):393-5.

PMID:
12478331
44.

Factor H family proteins: on complement, microbes and human diseases.

Zipfel PF, Skerka C, Hellwage J, Jokiranta ST, Meri S, Brade V, Kraiczy P, Noris M, Remuzzi G.

Biochem Soc Trans. 2002 Nov;30(Pt 6):971-8. Review.

PMID:
12440956
45.

Quality of Lyme disease serology. Lessons from the German Proficiency Testing Program 1999-2001. A preliminary report.

Hunfeld KP, Stanek G, Straube E, Hagedorn HJ, Schörner C, Mühlschlegel F, Brade V.

Wien Klin Wochenschr. 2002 Jul 31;114(13-14):591-600.

PMID:
12422607
46.

Development and laboratory evaluation of a new recombinant ELISA for the serodiagnosis of Lyme disease.

Hunfeld KP, Ernst M, Zachary P, Jaulhac B, Sonneborn HH, Brade V.

Wien Klin Wochenschr. 2002 Jul 31;114(13-14):580-5.

PMID:
12422605
47.

Complement regulator-acquiring surface proteins of Borrelia burgdorferi: a new protein family involved in complement resistance.

Kraiczy P, Skerka C, Zipfel PF, Brade V.

Wien Klin Wochenschr. 2002 Jul 31;114(13-14):568-73. Review.

PMID:
12422603
48.

Clinical quiz. Disseminated dermatitis.

Enzensberger R, Hunfeld KP, Elshorst-Schmidt T, Böer A, Brade V.

Infection. 2002 Oct;30(5):292. No abstract available.

PMID:
12420735
49.

Biological cost of rifampin resistance from the perspective of Staphylococcus aureus.

Wichelhaus TA, Böddinghaus B, Besier S, Schäfer V, Brade V, Ludwig A.

Antimicrob Agents Chemother. 2002 Nov;46(11):3381-5.

50.

[Osteomyelitis of the tibial head caused by Mycobacterium haemophilium in a patient with AIDS].

Gruschke A, Enzensberger R, Brade V.

Dtsch Med Wochenschr. 2002 Sep 20;127(38):1947-50. German.

PMID:
12239654

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