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Clinician-Facilitated Physical Activity Intervention Versus Pulmonary Rehabilitation for Improving Physical Activity in COPD: A Feasibility Study.

O'Neill B, O'Shea O, McDonough S, McGarvey L, Bradbury I, Arden M, Troosters T, Cosgrove D, McManus T, McDonnell T, Bradley J.

COPD. 2018 Sep 5:1-11. doi: 10.1080/15412555.2018.1486396. [Epub ahead of print]


Environmental extremes drive population structure at the northern range limit of Atlantic salmon in North America.

Sylvester EVA, Beiko RG, Bentzen P, Paterson I, Horne JB, Watson B, Lehnert S, Duffy S, Clément M, Robertson MJ, Bradbury IR.

Mol Ecol. 2018 Aug 27. doi: 10.1111/mec.14849. [Epub ahead of print]


PMERGE: Computational filtering of paralogous sequences from RAD-seq data.

Nadukkalam Ravindran P, Bentzen P, Bradbury IR, Beiko RG.

Ecol Evol. 2018 Jun 11;8(14):7002-7013. doi: 10.1002/ece3.4219. eCollection 2018 Jul.


Genotyping-by-sequencing of genome-wide microsatellite loci reveals fine-scale harvest composition in a coastal Atlantic salmon fishery.

Bradbury IR, Wringe BF, Watson B, Paterson I, Horne J, Beiko R, Lehnert SJ, Clément M, Anderson EC, Jeffery NW, Duffy S, Sylvester E, Robertson M, Bentzen P.

Evol Appl. 2018 Mar 11;11(6):918-930. doi: 10.1111/eva.12606. eCollection 2018 Jul.


Genomewide evidence of environmentally mediated secondary contact of European green crab (Carcinus maenas) lineages in eastern North America.

Jeffery NW, Bradbury IR, Stanley RRE, Wringe BF, Van Wyngaarden M, Lowen JB, McKenzie CH, Matheson K, Sargent PS, DiBacco C.

Evol Appl. 2018 Feb 23;11(6):869-882. doi: 10.1111/eva.12601. eCollection 2018 Jul.


Education of healthcare professionals for preventing pressure ulcers.

Porter-Armstrong AP, Moore ZE, Bradbury I, McDonough S.

Cochrane Database Syst Rev. 2018 May 25;5:CD011620. doi: 10.1002/14651858.CD011620.pub2. Review.


Fine-scale temperature-associated genetic structure between inshore and offshore populations of sea scallop (Placopecten magellanicus).

Lehnert SJ, DiBacco C, Van Wyngaarden M, Jeffery NW, Ben Lowen J, Sylvester EVA, Wringe BF, Stanley RRE, Hamilton LC, Bradbury IR.

Heredity (Edinb). 2018 May 17. doi: 10.1038/s41437-018-0087-9. [Epub ahead of print]


A climate-associated multispecies cryptic cline in the northwest Atlantic.

Stanley RRE, DiBacco C, Lowen B, Beiko RG, Jeffery NW, Van Wyngaarden M, Bentzen P, Brickman D, Benestan L, Bernatchez L, Johnson C, Snelgrove PVR, Wang Z, Wringe BF, Bradbury IR.

Sci Adv. 2018 Mar 28;4(3):eaaq0929. doi: 10.1126/sciadv.aaq0929. eCollection 2018 Mar.


Oceanographic variation influences spatial genomic structure in the sea scallop, Placopecten magellanicus.

Van Wyngaarden M, Snelgrove PVR, DiBacco C, Hamilton LC, Rodríguez-Ezpeleta N, Zhan L, Beiko RG, Bradbury IR.

Ecol Evol. 2018 Feb 11;8(5):2824-2841. doi: 10.1002/ece3.3846. eCollection 2018 Mar.


Applications of random forest feature selection for fine-scale genetic population assignment.

Sylvester EVA, Bentzen P, Bradbury IR, Clément M, Pearce J, Horne J, Beiko RG.

Evol Appl. 2017 Sep 14;11(2):153-165. doi: 10.1111/eva.12524. eCollection 2018 Feb.


Range-wide parallel climate-associated genomic clines in Atlantic salmon.

Jeffery NW, Stanley RRE, Wringe BF, Guijarro-Sabaniel J, Bourret V, Bernatchez L, Bentzen P, Beiko RG, Gilbey J, Clément M, Bradbury IR.

R Soc Open Sci. 2017 Nov 15;4(11):171394. doi: 10.1098/rsos.171394. eCollection 2017 Nov.


Cardiac biomarkers for early detection and prediction of trastuzumab and/or lapatinib-induced cardiotoxicity in patients with HER2-positive early-stage breast cancer: a NeoALTTO sub-study (BIG 1-06).

Ponde N, Bradbury I, Lambertini M, Ewer M, Campbell C, Ameels H, Zardavas D, Di Cosimo S, Baselga J, Huober J, Izquierdo M, Fumagalli D, Bozovic-Spasojevic I, Maetens M, Harbeck N, Pusztai L, Berghorn M, Im YH, Borrego MR, Chen DR, Rodeheffer R, Piccart M, Suter T, de Azambuja E.

Breast Cancer Res Treat. 2018 Apr;168(3):631-638. doi: 10.1007/s10549-017-4628-3. Epub 2017 Dec 27.


Ancient chromosomal rearrangement associated with local adaptation of a postglacially colonized population of Atlantic Cod in the northwest Atlantic.

Sinclair-Waters M, Bradbury IR, Morris CJ, Lien S, Kent MP, Bentzen P.

Mol Ecol. 2018 Jan;27(2):339-351. doi: 10.1111/mec.14442. Epub 2017 Dec 27.


Evolutionary genetics of immunological supertypes reveals two faces of the Red Queen.

Lighten J, Papadopulos AST, Mohammed RS, Ward BJ, G Paterson I, Baillie L, Bradbury IR, Hendry AP, Bentzen P, van Oosterhout C.

Nat Commun. 2017 Nov 3;8(1):1294. doi: 10.1038/s41467-017-01183-2.


Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions.

Berg PR, Star B, Pampoulie C, Bradbury IR, Bentzen P, Hutchings JA, Jentoft S, Jakobsen KS.

Heredity (Edinb). 2017 Dec;119(6):418-428. doi: 10.1038/hdy.2017.54. Epub 2017 Sep 20.


hybriddetective: A workflow and package to facilitate the detection of hybridization using genomic data in r.

Wringe BF, Stanley RRE, Jeffery NW, Anderson EC, Bradbury IR.

Mol Ecol Resour. 2017 Nov;17(6):e275-e284. doi: 10.1111/1755-0998.12704. Epub 2017 Sep 18.


RAD sequencing reveals genomewide divergence between independent invasions of the European green crab (Carcinus maenas) in the Northwest Atlantic.

Jeffery NW, DiBacco C, Van Wyngaarden M, Hamilton LC, Stanley RRE, Bernier R, FitzGerald J, Matheson K, McKenzie CH, Nadukkalam Ravindran P, Beiko R, Bradbury IR.

Ecol Evol. 2017 Mar 14;7(8):2513-2524. doi: 10.1002/ece3.2872. eCollection 2017 Apr.


Genomic evidence of hybridization between two independent invasions of European green crab (Carcinus maenas) in the Northwest Atlantic.

Jeffery NW, DiBacco C, Wringe BF, Stanley RRE, Hamilton LC, Ravindran PN, Bradbury IR.

Heredity (Edinb). 2017 Sep;119(3):154-165. doi: 10.1038/hdy.2017.22. Epub 2017 Apr 19.


Impact of Diabetes, Insulin, and Metformin Use on the Outcome of Patients With Human Epidermal Growth Factor Receptor 2-Positive Primary Breast Cancer: Analysis From the ALTTO Phase III Randomized Trial.

Sonnenblick A, Agbor-Tarh D, Bradbury I, Di Cosimo S, Azim HA Jr, Fumagalli D, Sarp S, Wolff AC, Andersson M, Kroep J, Cufer T, Simon SD, Salman P, Toi M, Harris L, Gralow J, Keane M, Moreno-Aspitia A, Piccart-Gebhart M, de Azambuja E.

J Clin Oncol. 2017 May 1;35(13):1421-1429. doi: 10.1200/JCO.2016.69.7722. Epub 2017 Mar 13.


Online support groups for women with breast cancer.

McCaughan E, Parahoo K, Hueter I, Northouse L, Bradbury I.

Cochrane Database Syst Rev. 2017 Mar 10;3:CD011652. doi: 10.1002/14651858.CD011652.pub2. Review.


Timing of hypertonic saline and airway clearance techniques in adults with cystic fibrosis during pulmonary exacerbation: pilot data from a randomised crossover study.

O'Neill K, Moran F, Tunney MM, Elborn JS, Bradbury I, Downey DG, Rendall J, Bradley JM.

BMJ Open Respir Res. 2017 Jan 12;4(1):e000168. doi: 10.1136/bmjresp-2016-000168. eCollection 2017.


Treatment of the axilla in patients with primary breast cancer and low burden axillary disease: Limitations of the evidence from randomised controlled trials.

Robertson JF, Herrod PJ, Matthew J, Kilburn LS, Coles CE, Bradbury I.

Crit Rev Oncol Hematol. 2017 Feb;110:74-80. doi: 10.1016/j.critrevonc.2016.11.011. Epub 2016 Nov 25. Review.


Comparing accelerometer, pedometer and a questionnaire for measuring physical activity in bronchiectasis: a validity and feasibility study?

O'Neill B, McDonough SM, Wilson JJ, Bradbury I, Hayes K, Kirk A, Kent L, Cosgrove D, Bradley JM, Tully MA.

Respir Res. 2017 Jan 14;18(1):16. doi: 10.1186/s12931-016-0497-2.


Identifying patterns of dispersal, connectivity and selection in the sea scallop, Placopecten magellanicus, using RADseq-derived SNPs.

Van Wyngaarden M, Snelgrove PV, DiBacco C, Hamilton LC, Rodríguez-Ezpeleta N, Jeffery NW, Stanley RR, Bradbury IR.

Evol Appl. 2016 Nov 2;10(1):102-117. doi: 10.1111/eva.12432. eCollection 2017 Jan.


Adaptive phenotypic response to climate enabled by epigenetics in a K-strategy species, the fish Leucoraja ocellata (Rajidae).

Lighten J, Incarnato D, Ward BJ, van Oosterhout C, Bradbury I, Hanson M, Bentzen P.

R Soc Open Sci. 2016 Oct 26;3(10):160299. eCollection 2016 Oct.


RNA Sequencing to Predict Response to Neoadjuvant Anti-HER2 Therapy: A Secondary Analysis of the NeoALTTO Randomized Clinical Trial.

Fumagalli D, Venet D, Ignatiadis M, Azim HA Jr, Maetens M, Rothé F, Salgado R, Bradbury I, Pusztai L, Harbeck N, Gomez H, Chang TW, Coccia-Portugal MA, Di Cosimo S, de Azambuja E, de la Peña L, Nuciforo P, Brase JC, Huober J, Baselga J, Piccart M, Loi S, Sotiriou C.

JAMA Oncol. 2016 Sep 29. doi: 10.1001/jamaoncol.2016.3824. [Epub ahead of print]


parallelnewhybrid: an R package for the parallelization of hybrid detection using newhybrids.

Wringe BF, Stanley RR, Jeffery NW, Anderson EC, Bradbury IR.

Mol Ecol Resour. 2017 Jan;17(1):91-95. doi: 10.1111/1755-0998.12597. Epub 2016 Oct 1.


genepopedit: a simple and flexible tool for manipulating multilocus molecular data in R.

Stanley RR, Jeffery NW, Wringe BF, DiBacco C, Bradbury IR.

Mol Ecol Resour. 2017 Jan;17(1):12-18. doi: 10.1111/1755-0998.12569. Epub 2016 Aug 11.


Lung Clearance Index in Adults and Children With Cystic Fibrosis.

O'Neill K, Tunney MM, Johnston E, Rowan S, Downey DG, Rendall J, Reid A, Bradbury I, Elborn JS, Bradley JM.

Chest. 2016 Dec;150(6):1323-1332. doi: 10.1016/j.chest.2016.06.029. Epub 2016 Jul 6.


megasat: automated inference of microsatellite genotypes from sequence data.

Zhan L, Paterson IG, Fraser BA, Watson B, Bradbury IR, Nadukkalam Ravindran P, Reznick D, Beiko RG, Bentzen P.

Mol Ecol Resour. 2017 Mar;17(2):247-256. doi: 10.1111/1755-0998.12561. Epub 2016 Jul 19.


Don't bet against the natal homing abilities of marine fishes.

Bentzen P, Bradbury IR.

Mol Ecol. 2016 Jun;25(12):2691-2. doi: 10.1111/mec.13591.


Lapatinib-Related Rash and Breast Cancer Outcome in the ALTTO Phase III Randomized Trial.

Sonnenblick A, de Azambuja E, Agbor-Tarh D, Bradbury I, Campbell C, Huang Y, Dueck AC, Pritchard KI, Wolff AC, Jackisch C, Lang I, Untch M, Smith I, Boyle F, Xu B, Gomez H, Perez EA, Piccart M, Azim HA Jr.

J Natl Cancer Inst. 2016 Apr 20;108(8). pii: djw037. doi: 10.1093/jnci/djw037. Print 2016 Aug.


Population structure of Atlantic mackerel inferred from RAD-seq-derived SNP markers: effects of sequence clustering parameters and hierarchical SNP selection.

Rodríguez-Ezpeleta N, Bradbury IR, Mendibil I, Álvarez P, Cotano U, Irigoien X.

Mol Ecol Resour. 2016 Jul;16(4):991-1001. doi: 10.1111/1755-0998.12518. Epub 2016 Mar 22.


Evidence from a Randomized Trial That Exposure to Supplemental Folic Acid at Recommended Levels during Pregnancy Does Not Lead to Increased Unmetabolized Folic Acid Concentrations in Maternal or Cord Blood.

Pentieva K, Selhub J, Paul L, Molloy AM, McNulty B, Ward M, Marshall B, Dornan J, Reilly R, Parle-McDermott A, Bradbury I, Ozaki M, Scott JM, McNulty H.

J Nutr. 2016 Mar;146(3):494-500. doi: 10.3945/jn.115.223644. Epub 2016 Jan 27.


Physical performance tests predict injury in National Collegiate Athletic Association athletes: a three-season prospective cohort study.

Hegedus EJ, McDonough S, Bleakley C, Baxter GD, DePew JT, Bradbury I, Cook C.

Br J Sports Med. 2016 Nov;50(21):1333-1337. doi: 10.1136/bjsports-2015-094885. Epub 2016 Jan 8.


Applying the Transtheoretical Model to Physical Activity Behavior in Individuals With Non-Cystic Fibrosis Bronchiectasis.

Wilson JJ, Kirk A, Hayes K, Bradbury I, McDonough S, Tully MA, O'Neill B, Bradley JM.

Respir Care. 2016 Jan;61(1):68-77. doi: 10.4187/respcare.04154. Epub 2015 Dec 8.


Reply to A. Oguz et al.

O'Sullivan CC, Holmes E, Campbell C, Bradbury I, Zujewski JA, Gelber RD.

J Clin Oncol. 2016 Feb 20;34(6):640-1. doi: 10.1200/JCO.2015.65.1034. Epub 2015 Dec 7. No abstract available.


Annotated mitochondrial genome assemblies for two sand lances (genus: Ammodytes) from the northwest Atlantic.

Horne JB, Mcbride MC, Lighten J, Bradbury IR, Bentzen P.

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 Nov;27(6):4607-4608. Epub 2015 Dec 7.


Transatlantic secondary contact in Atlantic Salmon, comparing microsatellites, a single nucleotide polymorphism array and restriction-site associated DNA sequencing for the resolution of complex spatial structure.

Bradbury IR, Hamilton LC, Dempson B, Robertson MJ, Bourret V, Bernatchez L, Verspoor E.

Mol Ecol. 2015 Oct;24(20):5130-44. doi: 10.1111/mec.13395.


Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab: A Secondary Analysis of the NeoALTTO Trial.

Salgado R, Denkert C, Campbell C, Savas P, Nuciforo P, Aura C, de Azambuja E, Eidtmann H, Ellis CE, Baselga J, Piccart-Gebhart MJ, Michiels S, Bradbury I, Sotiriou C, Loi S.

JAMA Oncol. 2015 Jul;1(4):448-54. doi: 10.1001/jamaoncol.2015.0830. Erratum in: JAMA Oncol. 2015 Nov;1(8):1172. Nucifero, Paolo [corrected to Nuciforo, Paolo]. JAMA Oncol. 2015 Jul;1(4):544.


Complete mitochondrial genomes for Icelus spatula, Aspidophoroides olrikii and Leptoclinus maculatus: pan-Arctic marine fishes from Canadian waters.

Swanburg T, Horne JB, Baillie S, King SD, McBride MC, Mackley MP, Paterson IG, Bradbury IR, Bentzen P.

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 Jul;27(4):2982-3. doi: 10.3109/19401736.2015.1060472. Epub 2015 Jun 30.


Efficacy of Adjuvant Trastuzumab for Patients With Human Epidermal Growth Factor Receptor 2-Positive Early Breast Cancer and Tumors ≤ 2 cm: A Meta-Analysis of the Randomized Trastuzumab Trials.

O'Sullivan CC, Bradbury I, Campbell C, Spielmann M, Perez EA, Joensuu H, Costantino JP, Delaloge S, Rastogi P, Zardavas D, Ballman KV, Holmes E, de Azambuja E, Piccart-Gebhart M, Zujewski JA, Gelber RD.

J Clin Oncol. 2015 Aug 20;33(24):2600-8. doi: 10.1200/JCO.2015.60.8620. Epub 2015 Jun 22.


Reduced bacterial colony count of anaerobic bacteria is associated with a worsening in lung clearance index and inflammation in cystic fibrosis.

O'Neill K, Bradley JM, Johnston E, McGrath S, McIlreavey L, Rowan S, Reid A, Bradbury I, Einarsson G, Elborn JS, Tunney MM.

PLoS One. 2015 May 20;10(5):e0126980. doi: 10.1371/journal.pone.0126980. eCollection 2015.


Sedentary behaviour and physical activity in bronchiectasis: a cross-sectional study.

Bradley JM, Wilson JJ, Hayes K, Kent L, McDonough S, Tully MA, Bradbury I, Kirk A, Cosgrove D, Convery R, Kelly M, Elborn JS, O'Neill B.

BMC Pulm Med. 2015 May 13;15:61. doi: 10.1186/s12890-015-0046-7.


Shortened Lung Clearance Index is a repeatable and sensitive test in children and adults with cystic fibrosis.

Hannon D, Bradley JM, Bradbury I, Bell N, Elborn JS, O'Neill K.

BMJ Open Respir Res. 2014 Jul 21;1(1):e000031. doi: 10.1136/bmjresp-2014-000031. eCollection 2014.


High HER2 expression correlates with response to the combination of lapatinib and trastuzumab.

Scaltriti M, Nuciforo P, Bradbury I, Sperinde J, Agbor-Tarh D, Campbell C, Chenna A, Winslow J, Serra V, Parra JL, Prudkin L, Jimenez J, Aura C, Harbeck N, Pusztai L, Ellis C, Eidtmann H, Arribas J, Cortes J, de Azambuja E, Piccart M, Baselga J.

Clin Cancer Res. 2015 Feb 1;21(3):569-76. doi: 10.1158/1078-0432.CCR-14-1824. Epub 2014 Dec 2.


Conservation genomics of anadromous Atlantic salmon across its North American range: outlier loci identify the same patterns of population structure as neutral loci.

Moore JS, Bourret V, Dionne M, Bradbury I, O'Reilly P, Kent M, Chaput G, Bernatchez L.

Mol Ecol. 2014 Dec;23(23):5680-97. doi: 10.1111/mec.12972. Epub 2014 Nov 8.


Long distance linkage disequilibrium and limited hybridization suggest cryptic speciation in atlantic cod.

Bradbury IR, Bowman S, Borza T, Snelgrove PV, Hutchings JA, Berg PR, Rodríguez-Ezpeleta N, Lighten J, Ruzzante DE, Taggart C, Bentzen P.

PLoS One. 2014 Sep 26;9(9):e106380. doi: 10.1371/journal.pone.0106380. eCollection 2014.


Reply to C. Fontanella et al.

Azim HA Jr, de Azambuja E, Agbor-Tarh D, Bradbury I.

J Clin Oncol. 2014 Oct 20;32(30):3459. doi: 10.1200/JCO.2014.57.0945. Epub 2014 Sep 15. No abstract available.


Palindromic sequence artifacts generated during next generation sequencing library preparation from historic and ancient DNA.

Star B, Nederbragt AJ, Hansen MH, Skage M, Gilfillan GD, Bradbury IR, Pampoulie C, Stenseth NC, Jakobsen KS, Jentoft S.

PLoS One. 2014 Mar 7;9(3):e89676. doi: 10.1371/journal.pone.0089676. eCollection 2014. Erratum in: PLoS One. 2014;9(7):e103170.

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