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Items: 1 to 50 of 62

1.

Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury.

Burnside ER, De Winter F, Didangelos A, James ND, Andreica EC, Layard-Horsfall H, Muir EM, Verhaagen J, Bradbury EJ.

Brain. 2018 Jun 14. doi: 10.1093/brain/awy158. [Epub ahead of print]

PMID:
29912283
2.

Combined Transcriptomics, Proteomics and Bioinformatics Identify Drug Targets in Spinal Cord Injury.

Tica J, Bradbury EJ, Didangelos A.

Int J Mol Sci. 2018 May 14;19(5). pii: E1461. doi: 10.3390/ijms19051461.

3.

'Chase': in dogged pursuit of a therapy for spinal cord injury.

Moon LDF, Bradbury EJ.

Brain. 2018 Apr 1;141(4):941-943. doi: 10.1093/brain/awy067. No abstract available.

PMID:
29596667
4.

Structural and Functional Substitution of Deleted Primary Sensory Neurons by New Growth from Intrinsic Spinal Cord Nerve Cells: An Alternative Concept in Reconstruction of Spinal Cord Circuits.

James ND, Angéria M, Bradbury EJ, Damberg P, McMahon SB, Risling M, Carlstedt T.

Front Neurol. 2017 Jul 24;8:358. doi: 10.3389/fneur.2017.00358. eCollection 2017.

5.

Comparative Phytochemical Analysis of Chinese and Bay Starvine (Schisandra spp.): Potential for Development as a New Dietary Supplement Ingredient.

Lyles JT, Tyler P, Bradbury EJ, Nelson K, Brown CF, Pierce ST, Quave CL.

J Diet Suppl. 2017 Nov 2;14(6):640-652. doi: 10.1080/19390211.2017.1304483. Epub 2017 Apr 6.

PMID:
28384001
6.

The soft mechanical signature of glial scars in the central nervous system.

Moeendarbary E, Weber IP, Sheridan GK, Koser DE, Soleman S, Haenzi B, Bradbury EJ, Fawcett J, Franze K.

Nat Commun. 2017 Mar 20;8:14787. doi: 10.1038/ncomms14787.

7.

Neuregulin-1 controls an endogenous repair mechanism after spinal cord injury.

Bartus K, Galino J, James ND, Hernandez-Miranda LR, Dawes JM, Fricker FR, Garratt AN, McMahon SB, Ramer MS, Birchmeier C, Bennett DL, Bradbury EJ.

Brain. 2016 May;139(Pt 5):1394-416. doi: 10.1093/brain/aww039. Epub 2016 Mar 17.

PMID:
26993800
8.

The Expression of Inflammatory Mediators in Bladder Pain Syndrome.

Offiah I, Didangelos A, Dawes J, Cartwright R, Khullar V, Bradbury EJ, O'Sullivan S, Williams D, Chessell IP, Pallas K, Graham G, O'Reilly BA, McMahon SB.

Eur Urol. 2016 Aug;70(2):283-90. doi: 10.1016/j.eururo.2016.02.058. Epub 2016 Mar 7.

9.

High-throughput proteomics reveal alarmins as amplifiers of tissue pathology and inflammation after spinal cord injury.

Didangelos A, Puglia M, Iberl M, Sanchez-Bellot C, Roschitzki B, Bradbury EJ.

Sci Rep. 2016 Feb 22;6:21607. doi: 10.1038/srep21607.

10.

Chondroitinase gene therapy improves upper limb function following cervical contusion injury.

James ND, Shea J, Muir EM, Verhaagen J, Schneider BL, Bradbury EJ.

Exp Neurol. 2015 Sep;271:131-5. doi: 10.1016/j.expneurol.2015.05.022. Epub 2015 Jun 1.

11.

Large animal and primate models of spinal cord injury for the testing of novel therapies.

Kwon BK, Streijger F, Hill CE, Anderson AJ, Bacon M, Beattie MS, Blesch A, Bradbury EJ, Brown A, Bresnahan JC, Case CC, Colburn RW, David S, Fawcett JW, Ferguson AR, Fischer I, Floyd CL, Gensel JC, Houle JD, Jakeman LB, Jeffery ND, Jones LA, Kleitman N, Kocsis J, Lu P, Magnuson DS, Marsala M, Moore SW, Mothe AJ, Oudega M, Plant GW, Rabchevsky AS, Schwab JM, Silver J, Steward O, Xu XM, Guest JD, Tetzlaff W.

Exp Neurol. 2015 Jul;269:154-68. doi: 10.1016/j.expneurol.2015.04.008. Epub 2015 Apr 19.

PMID:
25902036
12.

Sulfonylureas--a novel treatment to reduce tissue damage after acute spinal cord injury?--Authors' reply.

Bradbury EJ, Ramer MS, Ramer LM.

Lancet Neurol. 2015 Apr;14(4):352-3. doi: 10.1016/S1474-4422(15)70038-4. No abstract available.

PMID:
25792092
13.

Regulation of IL-10 by chondroitinase ABC promotes a distinct immune response following spinal cord injury.

Didangelos A, Iberl M, Vinsland E, Bartus K, Bradbury EJ.

J Neurosci. 2014 Dec 3;34(49):16424-32. doi: 10.1523/JNEUROSCI.2927-14.2014.

14.

Restoring function after spinal cord injury: towards clinical translation of experimental strategies.

Ramer LM, Ramer MS, Bradbury EJ.

Lancet Neurol. 2014 Dec;13(12):1241-56. doi: 10.1016/S1474-4422(14)70144-9. Epub 2014 Nov 10. Review.

PMID:
25453463
15.

A pilot study of herbal medicine use in a Midwest Latino population.

Kiefer D, Tellez-Girón P, Bradbury EJ.

WMJ. 2014 Apr;113(2):64-71.

16.

Effect of dietary nonphytate phosphorus and calcium concentration on calcium appetite of broiler chicks.

Wilkinson SJ, Bradbury EJ, Bedford MR, Cowieson AJ.

Poult Sci. 2014 Jul;93(7):1695-703. doi: 10.3382/ps.2013-03537. Epub 2014 May 26.

PMID:
24864288
17.

Nutritional geometry of calcium and phosphorus nutrition in broiler chicks. The effect of different dietary calcium and phosphorus concentrations and ratios on nutrient digestibility.

Wilkinson SJ, Bradbury EJ, Thomson PC, Bedford MR, Cowieson AJ.

Animal. 2014 Jul;8(7):1080-8. doi: 10.1017/S1751731114001049. Epub 2014 May 19.

PMID:
24840343
18.

Nutritional geometry of calcium and phosphorus nutrition in broiler chicks. Growth performance, skeletal health and intake arrays.

Bradbury EJ, Wilkinson SJ, Cronin GM, Thomson PC, Bedford MR, Cowieson AJ.

Animal. 2014 Jul;8(7):1071-9. doi: 10.1017/S1751731114001037. Epub 2014 May 19.

PMID:
24840206
19.

Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury.

Bartus K, James ND, Didangelos A, Bosch KD, Verhaagen J, Yáñez-Muñoz RJ, Rogers JH, Schneider BL, Muir EM, Bradbury EJ.

J Neurosci. 2014 Apr 2;34(14):4822-36. doi: 10.1523/JNEUROSCI.4369-13.2014.

20.

Manipulating the extracellular matrix and its role in brain and spinal cord plasticity and repair.

Burnside ER, Bradbury EJ.

Neuropathol Appl Neurobiol. 2014 Feb;40(1):26-59. doi: 10.1111/nan.12114. Review.

PMID:
24438519
21.

Geographic differences in patterns of genetic differentiation among bitter and sweet manioc (Manihot esculenta subsp. esculenta; Euphorbiaceae).

Bradbury EJ, Duputié A, Delêtre M, Roullier C, Narváez-Trujillo A, Manu-Aduening JA, Emshwiller E, McKey D.

Am J Bot. 2013 May;100(5):857-66. doi: 10.3732/ajb.1200482. Epub 2013 Apr 2.

22.

Combination therapies.

Oudega M, Bradbury EJ, Ramer MS.

Handb Clin Neurol. 2012;109:617-36. doi: 10.1016/B978-0-444-52137-8.00038-3. Review.

PMID:
23098740
23.

Chondroitinase ABC promotes compensatory sprouting of the intact corticospinal tract and recovery of forelimb function following unilateral pyramidotomy in adult mice.

Starkey ML, Bartus K, Barritt AW, Bradbury EJ.

Eur J Neurosci. 2012 Dec;36(12):3665-78. doi: 10.1111/ejn.12017. Epub 2012 Oct 14.

24.

Chondroitinase ABC promotes plasticity of spinal reflexes following peripheral nerve injury.

Bosch KD, Bradbury EJ, Verhaagen J, Fawcett JW, McMahon SB.

Exp Neurol. 2012 Nov;238(1):64-78. doi: 10.1016/j.expneurol.2012.08.003. Epub 2012 Aug 20.

PMID:
22917776
25.

Re-wiring the spinal cord: introduction to the special issue on plasticity after spinal cord injury.

Bradbury EJ.

Exp Neurol. 2012 May;235(1):1-4. doi: 10.1016/j.expneurol.2012.03.004. Epub 2012 Mar 13. No abstract available.

PMID:
22440889
26.

Conduction failure following spinal cord injury: functional and anatomical changes from acute to chronic stages.

James ND, Bartus K, Grist J, Bennett DL, McMahon SB, Bradbury EJ.

J Neurosci. 2011 Dec 14;31(50):18543-55. doi: 10.1523/JNEUROSCI.4306-11.2011.

27.

Chondroitin sulphate proteoglycans: key modulators of spinal cord and brain plasticity.

Bartus K, James ND, Bosch KD, Bradbury EJ.

Exp Neurol. 2012 May;235(1):5-17. doi: 10.1016/j.expneurol.2011.08.008. Epub 2011 Aug 16. Review.

PMID:
21871887
28.

Delayed treatment with chondroitinase ABC reverses chronic atrophy of rubrospinal neurons following spinal cord injury.

Carter LM, McMahon SB, Bradbury EJ.

Exp Neurol. 2011 Mar;228(1):149-56. doi: 10.1016/j.expneurol.2010.12.023. Epub 2011 Jan 6.

PMID:
21215745
29.

Manipulating the glial scar: chondroitinase ABC as a therapy for spinal cord injury.

Bradbury EJ, Carter LM.

Brain Res Bull. 2011 Mar 10;84(4-5):306-16. doi: 10.1016/j.brainresbull.2010.06.015. Epub 2010 Jul 8. Review.

PMID:
20620201
30.

Neural progenitors promote axon growth in vitro and ex vivo but not following injury.

Webber DJ, Yip P, Bradbury EJ, Minger SL, McMahon SB.

J Stem Cells. 2009;4(1):1-16. doi: jsc.2009.4.1.1.

PMID:
20498687
31.

The yellow fluorescent protein (YFP-H) mouse reveals neuroprotection as a novel mechanism underlying chondroitinase ABC-mediated repair after spinal cord injury.

Carter LM, Starkey ML, Akrimi SF, Davies M, McMahon SB, Bradbury EJ.

J Neurosci. 2008 Dec 24;28(52):14107-20. doi: 10.1523/JNEUROSCI.2217-08.2008.

32.

Expression of the regeneration-associated protein SPRR1A in primary sensory neurons and spinal cord of the adult mouse following peripheral and central injury.

Starkey ML, Davies M, Yip PK, Carter LM, Wong DJ, McMahon SB, Bradbury EJ.

J Comp Neurol. 2009 Mar 1;513(1):51-68. doi: 10.1002/cne.21944.

33.

Chondroitinase ABC-mediated plasticity of spinal sensory function.

Cafferty WB, Bradbury EJ, Lidierth M, Jones M, Duffy PJ, Pezet S, McMahon SB.

J Neurosci. 2008 Nov 12;28(46):11998-2009. doi: 10.1523/JNEUROSCI.3877-08.2008.

34.

Effects of Etanercept and Minocycline in a rat model of spinal cord injury.

Marchand F, Tsantoulas C, Singh D, Grist J, Clark AK, Bradbury EJ, McMahon SB.

Eur J Pain. 2009 Aug;13(7):673-81. doi: 10.1016/j.ejpain.2008.08.001. Epub 2008 Oct 11.

PMID:
18849175
35.

Therapeutic time window for the application of chondroitinase ABC after spinal cord injury.

García-Alías G, Lin R, Akrimi SF, Story D, Bradbury EJ, Fawcett JW.

Exp Neurol. 2008 Apr;210(2):331-8. Epub 2007 Nov 21.

PMID:
18158149
36.
37.

Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.

Eickholt BJ, Ahmed AI, Davies M, Papakonstanti EA, Pearce W, Starkey ML, Bilancio A, Need AC, Smith AJ, Hall SM, Hamers FP, Giese KP, Bradbury EJ, Vanhaesebroeck B.

PLoS One. 2007 Sep 11;2(9):e869.

38.

Chondroitinase ABC promotes sprouting of intact and injured spinal systems after spinal cord injury.

Barritt AW, Davies M, Marchand F, Hartley R, Grist J, Yip P, McMahon SB, Bradbury EJ.

J Neurosci. 2006 Oct 18;26(42):10856-67.

39.

Lentiviral vector expressing retinoic acid receptor beta2 promotes recovery of function after corticospinal tract injury in the adult rat spinal cord.

Yip PK, Wong LF, Pattinson D, Battaglia A, Grist J, Bradbury EJ, Maden M, McMahon SB, Mazarakis ND.

Hum Mol Genet. 2006 Nov 1;15(21):3107-18. Epub 2006 Sep 19.

PMID:
16984961
40.

Spinal cord repair strategies: why do they work?

Bradbury EJ, McMahon SB.

Nat Rev Neurosci. 2006 Aug;7(8):644-53. Review.

PMID:
16858392
41.

Role of spinal microglia in rat models of peripheral nerve injury and inflammation.

Clark AK, Gentry C, Bradbury EJ, McMahon SB, Malcangio M.

Eur J Pain. 2007 Feb;11(2):223-30. Epub 2006 Mar 20.

PMID:
16545974
42.

A clonal cell line from immortalized olfactory ensheathing glia promotes functional recovery in the injured spinal cord.

Moreno-Flores MT, Bradbury EJ, Martín-Bermejo MJ, Agudo M, Lim F, Pastrana E, Avila J, Díaz-Nido J, McMahon SB, Wandosell F.

Mol Ther. 2006 Mar;13(3):598-608. Epub 2006 Jan 19.

43.

Assessing behavioural function following a pyramidotomy lesion of the corticospinal tract in adult mice.

Starkey ML, Barritt AW, Yip PK, Davies M, Hamers FP, McMahon SB, Bradbury EJ.

Exp Neurol. 2005 Oct;195(2):524-39.

PMID:
16051217
44.

Regulation of neuropilin 1 by spinal cord injury in adult rats.

Agudo M, Robinson M, Cafferty W, Bradbury EJ, Kilkenny C, Hunt SP, McMahon SB.

Mol Cell Neurosci. 2005 Mar;28(3):475-84.

PMID:
15737738
46.

NGF and GDNF ameliorate the increase in ATF3 expression which occurs in dorsal root ganglion cells in response to peripheral nerve injury.

Averill S, Michael GJ, Shortland PJ, Leavesley RC, King VR, Bradbury EJ, McMahon SB, Priestley JV.

Eur J Neurosci. 2004 Mar;19(6):1437-45.

PMID:
15066140
47.

Glial cell line-derived neurotrophic factor increases calcitonin gene-related peptide immunoreactivity in sensory and motoneurons in vivo.

Ramer MS, Bradbury EJ, Michael GJ, Lever IJ, McMahon SB.

Eur J Neurosci. 2003 Nov;18(10):2713-21.

PMID:
14656320
48.

A novel control mechanism based on GDNF modulation of somatostatin release from sensory neurones.

Malcangio M, Getting SJ, Grist J, Cunningham JR, Bradbury EJ, Charbel Issa P, Lever IJ, Pezet S, Perretti M.

FASEB J. 2002 May;16(7):730-2. Epub 2002 Mar 12.

PMID:
11978739
49.

Chondroitinase ABC promotes functional recovery after spinal cord injury.

Bradbury EJ, Moon LD, Popat RJ, King VR, Bennett GS, Patel PN, Fawcett JW, McMahon SB.

Nature. 2002 Apr 11;416(6881):636-40.

PMID:
11948352
50.

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