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Items: 32


Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells.

Eliazer S, Muncie JM, Christensen J, Sun X, D'Urso RS, Weaver VM, Brack AS.

Cell Stem Cell. 2019 Sep 3. pii: S1934-5909(19)30342-X. doi: 10.1016/j.stem.2019.08.007. [Epub ahead of print]


Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress.

Scaramozza A, Park D, Kollu S, Beerman I, Sun X, Rossi DJ, Lin CP, Scadden DT, Crist C, Brack AS.

Cell Stem Cell. 2019 Jun 6;24(6):944-957.e5. doi: 10.1016/j.stem.2019.03.020. Epub 2019 Apr 18.


Inferring cell state by quantitative motility analysis reveals a dynamic state system and broken detailed balance.

Kimmel JC, Chang AY, Brack AS, Marshall WF.

PLoS Comput Biol. 2018 Jan 16;14(1):e1005927. doi: 10.1371/journal.pcbi.1005927. eCollection 2018 Jan.


Muscle Stem Cells and Aging.

Hwang AB, Brack AS.

Curr Top Dev Biol. 2018;126:299-322. doi: 10.1016/bs.ctdb.2017.08.008. Epub 2017 Nov 16. Review.


Stem cells: Cause and consequence in aged-muscle decline.

Eliazer S, Brack AS.

Nature. 2016 Dec 15;540(7633):349-350. doi: 10.1038/nature20485. Epub 2016 Nov 30. No abstract available.


The ins and outs of muscle stem cell aging.

Brack AS, Muñoz-Cánoves P.

Skelet Muscle. 2016 Jan 18;6:1. doi: 10.1186/s13395-016-0072-z. eCollection 2016. Review.


Lost in Translation: Preserving Satellite Cell Function with Global Translational Control.

Eliazer S, Brack AS.

Cell Stem Cell. 2016 Jan 7;18(1):5-7. doi: 10.1016/j.stem.2015.12.006.


GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration.

Egerman MA, Cadena SM, Gilbert JA, Meyer A, Nelson HN, Swalley SE, Mallozzi C, Jacobi C, Jennings LL, Clay I, Laurent G, Ma S, Brachat S, Lach-Trifilieff E, Shavlakadze T, Trendelenburg AU, Brack AS, Glass DJ.

Cell Metab. 2015 Jul 7;22(1):164-74. doi: 10.1016/j.cmet.2015.05.010. Epub 2015 May 19.


The Spindle Assembly Checkpoint Safeguards Genomic Integrity of Skeletal Muscle Satellite Cells.

Kollu S, Abou-Khalil R, Shen C, Brack AS.

Stem Cell Reports. 2015 Jun 9;4(6):1061-74. doi: 10.1016/j.stemcr.2015.04.006. Epub 2015 May 7.


Pax7 is back.

Brack AS.

Skelet Muscle. 2014 Dec 14;4(1):24. doi: 10.1186/s13395-014-0024-4. eCollection 2014.


Lineage of origin in rhabdomyosarcoma informs pharmacological response.

Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, Brack AS, Wagers AJ, Rando TA, Capecchi MR, Marini FC, Ehler BR, Zarzabal LA, Goros MW, Michalek JE, Meltzer PS, Langenau DM, LeGallo RD, Mansoor A, Chen Y, Suelves M, Rubin BP, Keller C.

Genes Dev. 2014 Jul 15;28(14):1578-91. doi: 10.1101/gad.238733.114.


Early forming label-retaining muscle stem cells require p27kip1 for maintenance of the primitive state.

Chakkalakal JV, Christensen J, Xiang W, Tierney MT, Boscolo FS, Sacco A, Brack AS.

Development. 2014 Apr;141(8):1649-59. doi: 10.1242/dev.100842.


Cellular mechanisms of somatic stem cell aging.

Jung Y, Brack AS.

Curr Top Dev Biol. 2014;107:405-38. doi: 10.1016/B978-0-12-416022-4.00014-7. Review.


ISSCR 2013: back to Bean Town.

Brack AS, Hochedlinger K.

Stem Cell Reports. 2013;1(6):479-85. doi: 10.1016/j.stemcr.2013.12.004. Epub 2013 Dec 17.


Ageing of the heart reversed by youthful systemic factors!

Brack AS.

EMBO J. 2013 Aug 14;32(16):2189-90. doi: 10.1038/emboj.2013.162. Epub 2013 Jul 16.


An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis.

Li Z, Gilbert JA, Zhang Y, Zhang M, Qiu Q, Ramanujan K, Shavlakadze T, Eash JK, Scaramozza A, Goddeeris MM, Kirsch DG, Campbell KP, Brack AS, Glass DJ.

Dev Cell. 2012 Dec 11;23(6):1176-88. doi: 10.1016/j.devcel.2012.10.019. Epub 2012 Nov 21. Erratum in: Dev Cell. 2013 Jan 14;24(1):112.


The aged niche disrupts muscle stem cell quiescence.

Chakkalakal JV, Jones KM, Basson MA, Brack AS.

Nature. 2012 Oct 18;490(7420):355-60. doi: 10.1038/nature11438. Epub 2012 Sep 26.


Extrinsic Regulation of Satellite Cell Function and Muscle Regeneration Capacity during Aging.

Chakkalakal J, Brack A.

J Stem Cell Res Ther. 2012 Sep 26;Suppl 11:001.


Tissue-specific stem cells: lessons from the skeletal muscle satellite cell.

Brack AS, Rando TA.

Cell Stem Cell. 2012 May 4;10(5):504-14. doi: 10.1016/j.stem.2012.04.001. Review.


Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, Rossi DJ.

Cell Stem Cell. 2010 Nov 5;7(5):618-30. doi: 10.1016/j.stem.2010.08.012. Epub 2010 Sep 30.


Muscle stem cells and reversible quiescence: the role of sprouty.

Abou-Khalil R, Brack AS.

Cell Cycle. 2010 Jul 1;9(13):2575-80. doi: 10.4161/cc.9.13.12149. Review.


Sprouty1 regulates reversible quiescence of a self-renewing adult muscle stem cell pool during regeneration.

Shea KL, Xiang W, LaPorta VS, Licht JD, Keller C, Basson MA, Brack AS.

Cell Stem Cell. 2010 Feb 5;6(2):117-29. doi: 10.1016/j.stem.2009.12.015.


BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration.

Brack AS, Murphy-Seiler F, Hanifi J, Deka J, Eyckerman S, Keller C, Aguet M, Rando TA.

Dev Biol. 2009 Nov 1;335(1):93-105. doi: 10.1016/j.ydbio.2009.08.014. Epub 2009 Aug 21.


A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis.

Brack AS, Conboy IM, Conboy MJ, Shen J, Rando TA.

Cell Stem Cell. 2008 Jan 10;2(1):50-9. doi: 10.1016/j.stem.2007.10.006.


MyoD- and nerve-dependent maintenance of MyoD expression in mature muscle fibres acts through the DRR/PRR element.

Chargé SB, Brack AS, Bayol SA, Hughes SM.

BMC Dev Biol. 2008 Jan 23;8:5. doi: 10.1186/1471-213X-8-5.


Intrinsic changes and extrinsic influences of myogenic stem cell function during aging.

Brack AS, Rando TA.

Stem Cell Rev. 2007 Fall;3(3):226-37. Review.


Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis.

Brack AS, Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C, Rando TA.

Science. 2007 Aug 10;317(5839):807-10.


Muscle hypertrophy induced by the Ski protein: cyto-architecture and ultrastructure.

Bruusgaard JC, Brack AS, Hughes SM, Gundersen K.

Acta Physiol Scand. 2005 Oct;185(2):141-9.


Bifunctional rhodamine probes of Myosin regulatory light chain orientation in relaxed skeletal muscle fibers.

Brack AS, Brandmeier BD, Ferguson RE, Criddle S, Dale RE, Irving M.

Biophys J. 2004 Apr;86(4):2329-41.


In situ orientations of protein domains: troponin C in skeletal muscle fibers.

Ferguson RE, Sun YB, Mercier P, Brack AS, Sykes BD, Corrie JE, Trentham DR, Irving M.

Mol Cell. 2003 Apr;11(4):865-74.


Aging-related satellite cell differentiation defect occurs prematurely after Ski-induced muscle hypertrophy.

Chargé SB, Brack AS, Hughes SM.

Am J Physiol Cell Physiol. 2002 Oct;283(4):C1228-41.

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