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Items: 1 to 50 of 122

1.

Bioactivity of the Cymbopogon citratus (Poaceae) essential oil and its terpenoid constituents on the predatory bug, Podisus nigrispinus (Heteroptera: Pentatomidae).

Brügger BP, Martínez LC, Plata-Rueda A, Castro BMCE, Soares MA, Wilcken CF, Carvalho AG, Serrão JE, Zanuncio JC.

Sci Rep. 2019 Jun 7;9(1):8358. doi: 10.1038/s41598-019-44709-y.

2.

CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.

Hammerschmidt P, Ostkotte D, Nolte H, Gerl MJ, Jais A, Brunner HL, Sprenger HG, Awazawa M, Nicholls HT, Turpin-Nolan SM, Langer T, Krüger M, Brügger B, Brüning JC.

Cell. 2019 May 30;177(6):1536-1552.e23. doi: 10.1016/j.cell.2019.05.008.

PMID:
31150623
3.

Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness.

Wu J, Ma S, Sandhoff R, Ming Y, Hotz-Wagenblatt A, Timmerman V, Bonello-Palot N, Schlotter-Weigel B, Auer-Grumbach M, Seeman P, Löscher WN, Reindl M, Weiss F, Mah E, Weisshaar N, Madi A, Mohr K, Schlimbach T, Velasco Cárdenas RM, Koeppel J, Grünschläger F, Müller L, Baumeister M, Brügger B, Schmitt M, Wabnitz G, Samstag Y, Cui G.

Immunity. 2019 May 21;50(5):1218-1231.e5. doi: 10.1016/j.immuni.2019.03.005. Epub 2019 Apr 2.

PMID:
30952607
4.

Origin of Molecular Oxygen in Comets: Current Knowledge and Perspectives.

Luspay-Kuti A, Mousis O, Lunine JI, Ellinger Y, Pauzat F, Raut U, Bouquet A, Mandt KE, Maggiolo R, Ronnet T, Brugger B, Ozgurel O, Fuselier SA.

Space Sci Rev. 2018 Dec;214. pii: 115. doi: 10.1007/s11214-018-0541-2. Epub 2018 Oct 16.

PMID:
30613113
5.

A method for the quantitative determination of glycerophospholipid regioisomers by UPLC-ESI-MS/MS.

Wozny K, Lehmann WD, Wozny M, Akbulut BS, Brügger B.

Anal Bioanal Chem. 2019 Feb;411(4):915-924. doi: 10.1007/s00216-018-1517-5. Epub 2018 Dec 22.

6.

Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis.

Marx B, Hufbauer M, Zigrino P, Majewski S, Markiefka B, Sachsenheimer T, Brügger B, Akgül B.

Oncotarget. 2018 Sep 25;9(75):34142-34158. doi: 10.18632/oncotarget.26140. eCollection 2018 Sep 25.

7.

Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia.

Chowdhury A, Aich A, Jain G, Wozny K, Lüchtenborg C, Hartmann M, Bernhard O, Balleiniger M, Alfar EA, Zieseniss A, Toischer K, Guan K, Rizzoli SO, Brügger B, Fischer A, Katschinski DM, Rehling P, Dudek J.

Cell Rep. 2018 Oct 16;25(3):561-570.e6. doi: 10.1016/j.celrep.2018.09.057.

8.

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects.

van Hensbergen VP, Movert E, de Maat V, Lüchtenborg C, Le Breton Y, Lambeau G, Payré C, Henningham A, Nizet V, van Strijp JAG, Brügger B, Carlsson F, McIver KS, van Sorge NM.

PLoS Pathog. 2018 Oct 15;14(10):e1007348. doi: 10.1371/journal.ppat.1007348. eCollection 2018 Oct.

9.

Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy.

Fledrich R, Abdelaal T, Rasch L, Bansal V, Schütza V, Brügger B, Lüchtenborg C, Prukop T, Stenzel J, Rahman RU, Hermes D, Ewers D, Möbius W, Ruhwedel T, Katona I, Weis J, Klein D, Martini R, Brück W, Müller WC, Bonn S, Bechmann I, Nave KA, Stassart RM, Sereda MW.

Nat Commun. 2018 Aug 2;9(1):3025. doi: 10.1038/s41467-018-05420-0.

10.

Inconspicuous Little Allies: How Membrane Lipids Help Modulate Protein Function.

Brügger B.

ACS Cent Sci. 2018 May 23;4(5):530-531. doi: 10.1021/acscentsci.8b00283. Epub 2018 May 11. No abstract available.

11.

Molecular and structural architecture of polyQ aggregates in yeast.

Gruber A, Hornburg D, Antonin M, Krahmer N, Collado J, Schaffer M, Zubaite G, Lüchtenborg C, Sachsenheimer T, Brügger B, Mann M, Baumeister W, Hartl FU, Hipp MS, Fernández-Busnadiego R.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3446-E3453. doi: 10.1073/pnas.1717978115. Epub 2018 Mar 26.

12.

Brr6 and Brl1 locate to nuclear pore complex assembly sites to promote their biogenesis.

Zhang W, Neuner A, Rüthnick D, Sachsenheimer T, Lüchtenborg C, Brügger B, Schiebel E.

J Cell Biol. 2018 Mar 5;217(3):877-894. doi: 10.1083/jcb.201706024. Epub 2018 Feb 9.

13.

Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolomics as additional symptoms in a new patient with ATP6AP1-CDG.

Dimitrov B, Himmelreich N, Hipgrave Ederveen AL, Lüchtenborg C, Okun JG, Breuer M, Hutter AM, Carl M, Guglielmi L, Hellwig A, Thiemann KC, Jost M, Peters V, Staufner C, Hoffmann GF, Hackenberg A, Paramasivam N, Wiemann S, Eils R, Schlesner M, Strahl S, Brügger B, Wuhrer M, Christoph Korenke G, Thiel C.

Mol Genet Metab. 2018 Mar;123(3):364-374. doi: 10.1016/j.ymgme.2018.01.008. Epub 2018 Jan 31.

PMID:
29396028
14.

Mcp3 is a novel mitochondrial outer membrane protein that follows a unique IMP-dependent biogenesis pathway.

Sinzel M, Tan T, Wendling P, Kalbacher H, Özbalci C, Chelius X, Westermann B, Brügger B, Rapaport D, Dimmer KS.

EMBO Rep. 2017 Oct;18(10):1869. doi: 10.15252/embr.201745020. No abstract available.

15.

The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles.

Trautz B, Wiedemann H, Lüchtenborg C, Pierini V, Kranich J, Glass B, Kräusslich HG, Brocker T, Pizzato M, Ruggieri A, Brügger B, Fackler OT.

J Biol Chem. 2017 Aug 18;292(33):13702-13713. doi: 10.1074/jbc.M117.797332. Epub 2017 Jun 28.

16.

Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy.

Kleinecke S, Richert S, de Hoz L, Brügger B, Kungl T, Asadollahi E, Quintes S, Blanz J, McGonigal R, Naseri K, Sereda MW, Sachsenheimer T, Lüchtenborg C, Möbius W, Willison H, Baes M, Nave KA, Kassmann CM.

Elife. 2017 May 4;6. pii: e23332. doi: 10.7554/eLife.23332.

17.

Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.

Schonauer S, Körschen HG, Penno A, Rennhack A, Breiden B, Sandhoff K, Gutbrod K, Dörmann P, Raju DN, Haberkant P, Gerl MJ, Brügger B, Zigdon H, Vardi A, Futerman AH, Thiele C, Wachten D.

J Biol Chem. 2017 Apr 14;292(15):6177-6189. doi: 10.1074/jbc.M116.762831. Epub 2017 Mar 3.

18.

Multivariate approach to quantitative analysis of Aphis gossypii Glover (Hemiptera: Aphididae) and their natural enemy populations at different cotton spacings.

Malaquias JB, Ramalho FS, Dos S Dias CT, Brugger BP, S Lira AC, Wilcken CF, Pachú JK, Zanuncio JC.

Sci Rep. 2017 Feb 9;7:41740. doi: 10.1038/srep41740.

19.

Transcriptomic analysis displays the effect of (-)-roemerine on the motility and nutrient uptake in Escherichia coli.

Ayyildiz D, Arga KY, Avci FG, Altinisik FE, Gurer C, Gulsoy Toplan G, Kazan D, Wozny K, Brügger B, Mertoglu B, Sariyar Akbulut B.

Curr Genet. 2017 Aug;63(4):709-722. doi: 10.1007/s00294-016-0673-4. Epub 2016 Dec 24.

PMID:
28013396
20.

PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position.

Luján P, Varsano G, Rubio T, Hennrich ML, Sachsenheimer T, Gálvez-Santisteban M, Martín-Belmonte F, Gavin AC, Brügger B, Köhn M.

J Cell Sci. 2016 Nov 1;129(21):4130-4142. Epub 2016 Sep 21.

21.

Mcp3 is a novel mitochondrial outer membrane protein that follows a unique IMP-dependent biogenesis pathway.

Sinzel M, Tan T, Wendling P, Kalbacher H, Özbalci C, Chelius X, Westermann B, Brügger B, Rapaport D, Dimmer KS.

EMBO Rep. 2016 Jul;17(7):965-81. doi: 10.15252/embr.201541273. Epub 2016 May 24. Erratum in: EMBO Rep. 2017 Oct;18(10 ):1869.

22.

Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions.

Gerl MJ, Bittl V, Kirchner S, Sachsenheimer T, Brunner HL, Lüchtenborg C, Özbalci C, Wiedemann H, Wegehingel S, Nickel W, Haberkant P, Schultz C, Krüger M, Brügger B.

PLoS One. 2016 Apr 21;11(4):e0153009. doi: 10.1371/journal.pone.0153009. eCollection 2016.

23.

Morphology and Molecular Composition of Purified Bovine Viral Diarrhea Virus Envelope.

Callens N, Brügger B, Bonnafous P, Drobecq H, Gerl MJ, Krey T, Roman-Sosa G, Rümenapf T, Lambert O, Dubuisson J, Rouillé Y.

PLoS Pathog. 2016 Mar 3;12(3):e1005476. doi: 10.1371/journal.ppat.1005476. eCollection 2016 Mar.

24.

Cardiac-specific succinate dehydrogenase deficiency in Barth syndrome.

Dudek J, Cheng IF, Chowdhury A, Wozny K, Balleininger M, Reinhold R, Grunau S, Callegari S, Toischer K, Wanders RJ, Hasenfuß G, Brügger B, Guan K, Rehling P.

EMBO Mol Med. 2016 Feb 1;8(2):139-54. doi: 10.15252/emmm.201505644.

25.

Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions.

Haberkant P, Stein F, Höglinger D, Gerl MJ, Brügger B, Van Veldhoven PP, Krijgsveld J, Gavin AC, Schultz C.

ACS Chem Biol. 2016 Jan 15;11(1):222-30. doi: 10.1021/acschembio.5b00810. Epub 2015 Nov 25.

PMID:
26555438
26.

α1-Antitrypsin Combines with Plasma Fatty Acids and Induces Angiopoietin-like Protein 4 Expression.

Frenzel E, Wrenger S, Brügger B, Salipalli S, Immenschuh S, Aggarwal N, Lichtinghagen R, Mahadeva R, Marcondes AM, Dinarello CA, Welte T, Janciauskiene S.

J Immunol. 2015 Oct 15;195(8):3605-16. doi: 10.4049/jimmunol.1500740. Epub 2015 Sep 11.

27.

Inhibition of Ebola virus glycoprotein-mediated cytotoxicity by targeting its transmembrane domain and cholesterol.

Hacke M, Björkholm P, Hellwig A, Himmels P, Ruiz de Almodóvar C, Brügger B, Wieland F, Ernst AM.

Nat Commun. 2015 Jul 9;6:7688. doi: 10.1038/ncomms8688.

PMID:
26158910
28.

Quantitative analysis of the human T cell palmitome.

Morrison E, Kuropka B, Kliche S, Brügger B, Krause E, Freund C.

Sci Rep. 2015 Jun 26;5:11598. doi: 10.1038/srep11598.

29.

Homeostasis of phospholipids - The level of phosphatidylethanolamine tightly adapts to changes in ethanolamine plasmalogens.

Dorninger F, Brodde A, Braverman NE, Moser AB, Just WW, Forss-Petter S, Brügger B, Berger J.

Biochim Biophys Acta. 2015 Feb;1851(2):117-28. doi: 10.1016/j.bbalip.2014.11.005. Epub 2014 Nov 15.

30.

Tools to study lipid functions. Preface.

Brügger B, Brown A.

Biochim Biophys Acta. 2014 Aug;1841(8):1021. doi: 10.1016/j.bbalip.2014.06.001. No abstract available.

PMID:
24954117
31.

Identification of novel sphingolipid-binding motifs in mammalian membrane proteins.

Björkholm P, Ernst AM, Hacke M, Wieland F, Brügger B, von Heijne G.

Biochim Biophys Acta. 2014 Aug;1838(8):2066-70. doi: 10.1016/j.bbamem.2014.04.026. Epub 2014 May 2.

32.

Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architecture.

Harner ME, Unger AK, Izawa T, Walther DM, Ozbalci C, Geimer S, Reggiori F, Brügger B, Mann M, Westermann B, Neupert W.

Elife. 2014 Jan 1;3:e01684. doi: 10.7554/eLife.01684.

33.

Analysis of transmembrane domains and lipid modified peptides with matrix-assisted laser desorption ionization-time-of-flight mass spectrometry.

Gerl MJ, Sachsenheimer T, Grzybek M, Coskun U, Wieland FT, Brügger B.

Anal Chem. 2014 Apr 15;86(8):3722-6. doi: 10.1021/ac500446z. Epub 2014 Mar 24.

PMID:
24628620
34.

Lipidomics: analysis of the lipid composition of cells and subcellular organelles by electrospray ionization mass spectrometry.

Brügger B.

Annu Rev Biochem. 2014;83:79-98. doi: 10.1146/annurev-biochem-060713-035324. Epub 2014 Mar 3. Review.

PMID:
24606142
35.

Sphingolipids as modulators of membrane proteins.

Ernst AM, Brügger B.

Biochim Biophys Acta. 2014 May;1841(5):665-70. doi: 10.1016/j.bbalip.2013.10.016. Epub 2013 Nov 5. Review.

PMID:
24201378
36.

Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol.

Küch EM, Vellaramkalayil R, Zhang I, Lehnen D, Brügger B, Sreemmel W, Ehehalt R, Poppelreuther M, Füllekrug J.

Biochim Biophys Acta. 2014 Feb;1841(2):227-39.

PMID:
24201376
37.

Quantitative analysis of cellular lipids by nano-electrospray ionization mass spectrometry.

Özbalci C, Sachsenheimer T, Brügger B.

Methods Mol Biol. 2013;1033:3-20. doi: 10.1007/978-1-62703-487-6_1.

PMID:
23996167
38.

Synthesis and biological properties of novel brefeldin A analogues.

Seehafer K, Rominger F, Helmchen G, Langhans M, Robinson DG, Özata B, Brügger B, Strating JR, van Kuppeveld FJ, Klein CD.

J Med Chem. 2013 Jul 25;56(14):5872-84. doi: 10.1021/jm400615g. Epub 2013 Jul 8.

PMID:
23805957
39.

Mcp1 and Mcp2, two novel proteins involved in mitochondrial lipid homeostasis.

Tan T, Ozbalci C, Brügger B, Rapaport D, Dimmer KS.

J Cell Sci. 2013 Aug 15;126(Pt 16):3563-74. doi: 10.1242/jcs.121244. Epub 2013 Jun 18.

40.

Scission of COPI and COPII vesicles is independent of GTP hydrolysis.

Adolf F, Herrmann A, Hellwig A, Beck R, Brügger B, Wieland FT.

Traffic. 2013 Aug;14(8):922-32. doi: 10.1111/tra.12084. Epub 2013 Jun 10.

41.

Differential transport of Influenza A neuraminidase signal anchor peptides to the plasma membrane.

Ernst AM, Zacherl S, Herrmann A, Hacke M, Nickel W, Wieland FT, Brügger B.

FEBS Lett. 2013 May 2;587(9):1411-7. doi: 10.1016/j.febslet.2013.03.019. Epub 2013 Mar 21.

42.

In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids.

Haberkant P, Raijmakers R, Wildwater M, Sachsenheimer T, Brügger B, Maeda K, Houweling M, Gavin AC, Schultz C, van Meer G, Heck AJ, Holthuis JC.

Angew Chem Int Ed Engl. 2013 Apr 2;52(14):4033-8. doi: 10.1002/anie.201210178. Epub 2013 Feb 28. No abstract available.

PMID:
23450850
43.

Comparative lipidomics analysis of HIV-1 particles and their producer cell membrane in different cell lines.

Lorizate M, Sachsenheimer T, Glass B, Habermann A, Gerl MJ, Kräusslich HG, Brügger B.

Cell Microbiol. 2013 Feb;15(2):292-304. doi: 10.1111/cmi.12101. Epub 2013 Jan 10.

PMID:
23279151
44.

Sphingomyelin organization is required for vesicle biogenesis at the Golgi complex.

Duran JM, Campelo F, van Galen J, Sachsenheimer T, Sot J, Egorov MV, Rentero C, Enrich C, Polishchuk RS, Goñi FM, Brügger B, Wieland F, Malhotra V.

EMBO J. 2012 Dec 12;31(24):4535-46. doi: 10.1038/emboj.2012.317. Epub 2012 Nov 23.

45.

Poxvirus membrane biogenesis: rupture not disruption.

Krijnse Locker J, Chlanda P, Sachsenheimer T, Brügger B.

Cell Microbiol. 2013 Feb;15(2):190-9. doi: 10.1111/cmi.12072. Epub 2012 Dec 16. Review.

46.

Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes.

Krumpe K, Frumkin I, Herzig Y, Rimon N, Özbalci C, Brügger B, Rapaport D, Schuldiner M.

Mol Biol Cell. 2012 Oct;23(20):3927-35. doi: 10.1091/mbc.E11-12-0994. Epub 2012 Aug 23.

47.

Mutual recognition of sphingolipid molecular species in membranes.

Ernst AM, Contreras FX, Thiele C, Wieland F, Brügger B.

Biochim Biophys Acta. 2012 Nov;1818(11):2616-22. doi: 10.1016/j.bbamem.2012.06.004. Epub 2012 Jun 12.

48.

Lipids and vesicular transport.

Brügger B, Bankaitis VA.

Biochim Biophys Acta. 2012 Aug;1821(8):1039. doi: 10.1016/j.bbalip.2012.05.005. Epub 2012 May 26. No abstract available.

PMID:
22659299
49.

The structures of COPI-coated vesicles reveal alternate coatomer conformations and interactions.

Faini M, Prinz S, Beck R, Schorb M, Riches JD, Bacia K, Brügger B, Wieland FT, Briggs JA.

Science. 2012 Jun 15;336(6087):1451-4. doi: 10.1126/science.1221443. Epub 2012 May 24.

50.

Large membrane domains in hair bundles specify spatially constricted radixin activation.

Zhao H, Williams DE, Shin JB, Brügger B, Gillespie PG.

J Neurosci. 2012 Mar 28;32(13):4600-9. doi: 10.1523/JNEUROSCI.6184-11.2012.

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