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Changes in mechanical loading affect arthritis-induced bone loss in mice.

Liphardt AM, Windahl SH, Sehic E, Hannemann N, Gustafsson KL, Bozec A, Schett G, Engdahl C.

Bone. 2019 Nov 9:115149. doi: 10.1016/j.bone.2019.115149. [Epub ahead of print]


How Autoantibodies Regulate Osteoclast Induced Bone Loss in Rheumatoid Arthritis.

Steffen U, Schett G, Bozec A.

Front Immunol. 2019 Jul 3;10:1483. doi: 10.3389/fimmu.2019.01483. eCollection 2019. Review.


Evaluation of the information given to patients undergoing total pharyngolaryngectomy and quality of life: a prospective multicentric study.

Bozec A, Schultz P, Gal J, Chamorey E, Chateau Y, Dassonville O, Poissonnet G, Peyrade F, Saada E, Guigay J, Benezery K, Leysalle A, Santini L, Giovanni A, Messaoudi L, Fakhry N.

Eur Arch Otorhinolaryngol. 2019 Sep;276(9):2531-2539. doi: 10.1007/s00405-019-05513-6. Epub 2019 Jun 20.


Pharyngeal diverticulum: Iatrogenic complication of anterior cervical spine surgery.

Villarmé A, Bozec A, Santini J, Dassonville O.

Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Jun 6. pii: S1879-7296(19)30093-6. doi: 10.1016/j.anorl.2019.05.003. [Epub ahead of print]


Prevalence and characteristics of HPV-driven oropharyngeal cancer in France.

Mirghani H, Bellera C, Delaye J, Dolivet G, Fakhry N, Bozec A, Garrel R, Malard O, Jegoux F, Maingon P, Sarini J, Noel G, Duflo S, Temam S, Lefebvre JL, Costes-Martineau V.

Cancer Epidemiol. 2019 Aug;61:89-94. doi: 10.1016/j.canep.2019.05.007. Epub 2019 May 31.


Soluble CD83 Triggers Resolution of Arthritis and Sustained Inflammation Control in IDO Dependent Manner.

Royzman D, Andreev D, Stich L, Rauh M, Bäuerle T, Ellmann S, Boon L, Kindermann M, Peckert K, Bozec A, Schett G, Steinkasserer A, Zinser E.

Front Immunol. 2019 Apr 2;10:633. doi: 10.3389/fimmu.2019.00633. eCollection 2019.


Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis.

Hannemann N, Cao S, Eriksson D, Schnelzer A, Jordan J, Eberhardt M, Schleicher U, Rech J, Ramming A, Uebe S, Ekici A, Cañete JD, Chen X, Bäuerle T, Vera J, Bogdan C, Schett G, Bozec A.

J Clin Invest. 2019 Apr 16;129(7):2669-2684. doi: 10.1172/JCI96832.


Current role of primary surgical treatment in patients with head and neck squamous cell carcinoma.

Bozec A, Culié D, Poissonnet G, Dassonville O.

Curr Opin Oncol. 2019 May;31(3):138-145. doi: 10.1097/CCO.0000000000000531.


Evolution and predictive factors of quality of life in patients undergoing oncologic surgery for head and neck cancer: A prospective multicentric study.

Bozec A, Schultz P, Gal J, Chamorey E, Chateau Y, Dassonville O, Poissonnet G, Demard F, Peyrade F, Saada E, Benezery K, Leysalle A, Santini L, Messaoudi L, Fakhry N.

Surg Oncol. 2019 Mar;28:236-242. doi: 10.1016/j.suronc.2019.01.012. Epub 2019 Jan 28.


Fra1 Controls Rheumatoid Factor Autoantibody Production by Bone Marrow Plasma Cells and the Development of Autoimmune Bone Loss.

Grötsch B, Lux A, Rombouts Y, Hoffmann AC, Andreev D, Nimmerjahn F, Xiang W, Scherer HU, Schett G, Bozec A.

J Bone Miner Res. 2019 Jul;34(7):1352-1365. doi: 10.1002/jbmr.3705. Epub 2019 Mar 19.


In Vivo Models of Rheumatoid Arthritis.

Grötsch B, Bozec A, Schett G.

Methods Mol Biol. 2019;1914:269-280. doi: 10.1007/978-1-4939-8997-3_14.


Corrigendum to "Environmental contamination by bacteria in hospital washrooms according to hand-drying method: a multi-centre study" [J Hospital Infection 100 (2018) 469-475].

Best E, Parnell P, Couturier J, Barbut F, Le Bozec A, Arnoldo L, Madia A, Brusaferro S, Wilcox MH.

J Hosp Infect. 2019 Apr;101(4):487. doi: 10.1016/j.jhin.2019.01.014. Epub 2019 Jan 31. No abstract available.


An original procedure for orbitonasal cutaneous infiltrative tumor repair, using combined forehead and melolabial propeller flaps.

Vandersteen C, Culié D, Dassonville O, Bozec A, Guevara N, Savoldelli C, Poissonnet G.

Eur Arch Otorhinolaryngol. 2019 Feb;276(2):535-540. doi: 10.1007/s00405-018-5237-4. Epub 2018 Dec 5.


Total pharyngolaryngectomy in the elderly: The impact of age on postoperative complications and oncologic and functional outcomes.

Milliet F, Gal J, Chamorey E, Dassonville O, Poissonnet G, Peyrade F, Benezery K, Hechema R, Sudaka A, Sanchez-Luini M, Demard F, Santini J, Bozec A.

Surg Oncol. 2018 Dec;27(4):767-772. doi: 10.1016/j.suronc.2018.10.007. Epub 2018 Oct 11.


Versatility of cervicofacial flaps: Cervical-medial cheek flap for reconstruction in cutaneous substance loss of the inner cheek.

Hufschmidt K, Bozec A, Camuzard O, Clerico C, Berguiga R, Dassonville O, Santini J, Poissonnet G.

Head Neck. 2018 Dec;40(12):2574-2582. doi: 10.1002/hed.25183. Epub 2018 Nov 17.


Prediction of early metastatic disease in experimental breast cancer bone metastasis by combining PET/CT and MRI parameters to a Model-Averaged Neural Network.

Ellmann S, Seyler L, Evers J, Heinen H, Bozec A, Prante O, Kuwert T, Uder M, Bäuerle T.

Bone. 2019 Mar;120:254-261. doi: 10.1016/j.bone.2018.11.008. Epub 2018 Nov 13.


Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis.

Chen Z, Bozec A, Ramming A, Schett G.

Nat Rev Rheumatol. 2019 Jan;15(1):9-17. doi: 10.1038/s41584-018-0109-2. Review.


Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy.

Bertero T, Oldham WM, Grasset EM, Bourget I, Boulter E, Pisano S, Hofman P, Bellvert F, Meneguzzi G, Bulavin DV, Estrach S, Feral CC, Chan SY, Bozec A, Gaggioli C.

Cell Metab. 2019 Jan 8;29(1):124-140.e10. doi: 10.1016/j.cmet.2018.09.012. Epub 2018 Oct 4.


Fra-2 Expression in Osteoblasts Regulates Systemic Inflammation and Lung Injury through Osteopontin.

Luo Y, Grötsch B, Hannemann N, Jimenez M, Ipseiz N, Uluckan O, Lin N, Schett G, Wagner EF, Bozec A.

Mol Cell Biol. 2018 Oct 29;38(22). pii: e00022-18. doi: 10.1128/MCB.00022-18. Print 2018 Nov 15.


Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases.

Hahn J, Schauer C, Czegley C, Kling L, Petru L, Schmid B, Weidner D, Reinwald C, Biermann MHC, Blunder S, Ernst J, Lesner A, Bäuerle T, Palmisano R, Christiansen S, Herrmann M, Bozec A, Gruber R, Schett G, Hoffmann MH.

FASEB J. 2019 Jan;33(1):1401-1414. doi: 10.1096/fj.201800752R. Epub 2018 Aug 21.


Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells.

Grasset EM, Bertero T, Bozec A, Friard J, Bourget I, Pisano S, Lecacheur M, Maiel M, Bailleux C, Emelyanov A, Ilie M, Hofman P, Meneguzzi G, Duranton C, Bulavin DV, Gaggioli C.

Cancer Res. 2018 Sep 15;78(18):5229-5242. doi: 10.1158/0008-5472.CAN-18-0601. Epub 2018 Jul 19.


Environmental contamination by bacteria in hospital washrooms according to hand-drying method: a multi-centre study.

Best E, Parnell P, Couturier J, Barbut F, Le Bozec A, Arnoldo L, Madia A, Brusaferro S, Wilcox MH.

J Hosp Infect. 2018 Dec;100(4):469-475. doi: 10.1016/j.jhin.2018.07.002. Epub 2018 Jul 10. Erratum in: J Hosp Infect. 2019 Apr;101(4):487.


Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice.

Omata Y, Frech M, Primbs T, Lucas S, Andreev D, Scholtysek C, Sarter K, Kindermann M, Yeremenko N, Baeten DL, Andreas N, Kamradt T, Bozec A, Ramming A, Krönke G, Wirtz S, Schett G, Zaiss MM.

Cell Rep. 2018 Jul 3;24(1):169-180. doi: 10.1016/j.celrep.2018.06.005.


Role of supracricoid partial laryngectomy with cricohyoidoepiglottopexy in glottic carcinoma with anterior commissure involvement.

Pescetto B, Gal J, Chamorey E, Dassonville O, Poissonnet G, Bozec A.

Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Aug;135(4):249-253. doi: 10.1016/j.anorl.2018.05.004. Epub 2018 Jun 7.


Impact of HPV-associated p16-expression and other clinical factors on therapeutic decision-making in patients with oropharyngeal cancer: A GETTEC multicentric study.

Culié D, Garrel R, Viotti J, Schiappa R, Chamorey E, Fakhry N, Lallemant B, Vergez S, Dupret-Bories A, Dassonville O, Poissonnet G, Santini J, Peyrade F, Benezery K, Sudaka A, Jourdan-Soulier F, Chapel F, Guelfucci B, Bozec A.

Eur J Surg Oncol. 2018 Dec;44(12):1908-1913. doi: 10.1016/j.ejso.2018.05.022. Epub 2018 May 25.


[New insights into the function of bone marrow].

Schett G, Bozec A, Bekeredjian-Ding I, Chang HD, David JP, Dörner T, Grässel S, Gunzer M, Manz R, Mei H, Mielenz D, Müller-Ladner U, Neumann E, Radbruch A, Richter W, Straub RH.

Z Rheumatol. 2018 May;77(Suppl 1):4-7. doi: 10.1007/s00393-018-0456-z. Review. German. No abstract available.


Microsatellite instability associated with durable complete response to PD-L1 inhibitor in head and neck squamous cell carcinoma.

Tardy MP, Di Mauro I, Ebran N, Refae S, Bozec A, Benezery K, Peyrade F, Guigay J, Sudaka-Bahadoran A, Badoual C, Pedeutour F, Saada-Bouzid E.

Oral Oncol. 2018 May;80:104-107. doi: 10.1016/j.oraloncology.2018.04.001. Epub 2018 Apr 7. No abstract available.


New insights into the key role of HIF-1α in IL-10-producing B cells.

Meng X, Bozec A.

Cell Stress. 2018 Mar 22;2(4):94-95. doi: 10.15698/cst2018.04.133.


Long-term quality of life and psycho-social outcomes after oropharyngeal cancer surgery and radial forearm free-flap reconstruction: A GETTEC prospective multicentric study.

Bozec A, Demez P, Gal J, Chamorey E, Louis MY, Blanchard D, De Raucourt D, Merol JC, Brenet E, Dassonville O, Poissonnet G, Santini J, Peyrade F, Benezery K, Lesnik M, Berta E, Ransy P, Babin E.

Surg Oncol. 2018 Mar;27(1):23-30. doi: 10.1016/j.suronc.2017.11.005. Epub 2017 Nov 24.


Abatacept blocks anti-citrullinated protein antibody and rheumatoid factor mediated cytokine production in human macrophages in IDO-dependent manner.

Bozec A, Luo Y, Engdahl C, Figueiredo C, Bang H, Schett G.

Arthritis Res Ther. 2018 Feb 7;20(1):24. doi: 10.1186/s13075-018-1527-x.


Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease.

Meng X, Grötsch B, Luo Y, Knaup KX, Wiesener MS, Chen XX, Jantsch J, Fillatreau S, Schett G, Bozec A.

Nat Commun. 2018 Jan 17;9(1):251. doi: 10.1038/s41467-017-02683-x.


The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis.

Bergmann C, Brandt A, Merlevede B, Hallenberger L, Dees C, Wohlfahrt T, Pötter S, Zhang Y, Chen CW, Mallano T, Liang R, Kagwiria R, Kreuter A, Pantelaki I, Bozec A, Abraham D, Rieker R, Ramming A, Distler O, Schett G, Distler JHW.

Ann Rheum Dis. 2018 Jan;77(1):150-158. doi: 10.1136/annrheumdis-2017-211501. Epub 2017 Oct 25.


MiR-223-3p inhibits angiogenesis and promotes resistance to cetuximab in head and neck squamous cell carcinoma.

Bozec A, Zangari J, Butori-Pepino M, Ilie M, Lalvee S, Juhel T, Butori C, Brest P, Hofman P, Vouret-Craviari V.

Oncotarget. 2017 Jul 11;8(34):57174-57186. doi: 10.18632/oncotarget.19170. eCollection 2017 Aug 22.


[Reirradiation of head and neck cancers].

Doyen J, Lam Cham Kee D, Krebs L, Guigay J, Dassonville O, Peyrade F, Poissonnet G, Saâda-Bouzid E, Sudaka A, Bozec A, Bénézery K.

Cancer Radiother. 2017 Oct;21(6-7):521-526. doi: 10.1016/j.canrad.2017.07.023. Epub 2017 Aug 18. Review. French.


Galectin-3 as a novel regulator of osteoblast-osteoclast interaction and bone homeostasis.

Simon D, Derer A, Andes FT, Lezuo P, Bozec A, Schett G, Herrmann M, Harre U.

Bone. 2017 Dec;105:35-41. doi: 10.1016/j.bone.2017.08.013. Epub 2017 Aug 16.


Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells.

Rauber S, Luber M, Weber S, Maul L, Soare A, Wohlfahrt T, Lin NY, Dietel K, Bozec A, Herrmann M, Kaplan MH, Weigmann B, Zaiss MM, Fearon U, Veale DJ, Cañete JD, Distler O, Rivellese F, Pitzalis C, Neurath MF, McKenzie ANJ, Wirtz S, Schett G, Distler JHW, Ramming A.

Nat Med. 2017 Aug;23(8):938-944. doi: 10.1038/nm.4373. Epub 2017 Jul 17.


Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription.

Ubieta K, Garcia M, Grötsch B, Uebe S, Weber GF, Stein M, Ekici A, Schett G, Mielenz D, Bozec A.

J Exp Med. 2017 Jul 3;214(7):2059-2071. doi: 10.1084/jem.20160514. Epub 2017 May 31.


A defined metabolic state in pre B cells governs B-cell development and is counterbalanced by Swiprosin-2/EFhd1.

Stein M, Dütting S, Mougiakakos D, Bösl M, Fritsch K, Reimer D, Urbanczyk S, Steinmetz T, Schuh W, Bozec A, Winkler TH, Jäck HM, Mielenz D.

Cell Death Differ. 2017 Jul;24(7):1239-1252. doi: 10.1038/cdd.2017.52. Epub 2017 May 19.


T Regulatory Cells in Bone Remodelling.

Bozec A, Zaiss MM.

Curr Osteoporos Rep. 2017 Jun;15(3):121-125. doi: 10.1007/s11914-017-0356-1. Review.


The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages.

Hannemann N, Jordan J, Paul S, Reid S, Baenkler HW, Sonnewald S, Bäuerle T, Vera J, Schett G, Bozec A.

J Immunol. 2017 May 1;198(9):3605-3614. doi: 10.4049/jimmunol.1601330. Epub 2017 Mar 15.


Latest perspectives on macrophages in bone homeostasis.

Bozec A, Soulat D.

Pflugers Arch. 2017 Apr;469(3-4):517-525. doi: 10.1007/s00424-017-1952-8. Epub 2017 Feb 28. Review.


An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer.

Vallejo A, Perurena N, Guruceaga E, Mazur PK, Martinez-Canarias S, Zandueta C, Valencia K, Arricibita A, Gwinn D, Sayles LC, Chuang CH, Guembe L, Bailey P, Chang DK, Biankin A, Ponz-Sarvise M, Andersen JB, Khatri P, Bozec A, Sweet-Cordero EA, Sage J, Lecanda F, Vicent S.

Nat Commun. 2017 Feb 21;8:14294. doi: 10.1038/ncomms14294.


Coverage of Tendon Exposure after Radial Forearm Free Flap by the Dorsoulnar Artery Perforator Flap.

Foissac R, Benatar M, Dassonville O, Bozec A, Poissonnet G, Camuzard O.

Otolaryngol Head Neck Surg. 2017 May;156(5):822-827. doi: 10.1177/0194599817691931. Epub 2017 Feb 14.


Primary total laryngectomy and pharyngolaryngectomy in T4 pharyngolaryngeal cancers: Oncologic and functional results and prognostic factors.

Roux M, Dassonville O, Ettaiche M, Chamorey E, Poissonnet G, Bozec A.

Eur Ann Otorhinolaryngol Head Neck Dis. 2017 May;134(3):151-154. doi: 10.1016/j.anorl.2016.11.009. Epub 2016 Dec 14.


Transoral-transcervical oropharyngectomy without mandibulotomy, associated to fasciocutaneous radial forearm free-flap reconstruction, for oropharyngeal cancer: Postoperative course, oncologic and functional results, and prognostic factors.

Roux M, Dassonville O, Ettaiche M, Poissonnet G, Sudaka A, Bozec A.

Eur Ann Otorhinolaryngol Head Neck Dis. 2017 Apr;134(2):71-76. doi: 10.1016/j.anorl.2016.11.004. Epub 2016 Nov 30.


Multicenter prospective micro-costing study evaluating mandibular free-flap reconstruction.

Dassonville O, Bozec A, Château Y, Reyt E, Devauchelle B, Louis MY, Breton P, Julieron M, Yachouh J, Mallet Y, Sarini J, Dolivet G, Schiappa R, Gal J, Orlanducci MH, Poissonnet G, Chamorey E.

Eur Arch Otorhinolaryngol. 2017 Feb;274(2):1103-1111. doi: 10.1007/s00405-016-4360-3. Epub 2016 Oct 27.


Radiotherapy for elderly patients and cetuximab, a monocentric study.

Falk AT, Hébert C, Tran A, Chand ME, Leysalle A, Thariat J, Dassonville O, Poissonnet G, Bozec A, Saada E, Peyrade F, Benezery K.

Eur Arch Otorhinolaryngol. 2017 Feb;274(2):1061-1065. doi: 10.1007/s00405-016-4336-3. Epub 2016 Oct 11.


Evaluation of the information given to patients undergoing head and neck cancer surgery using the EORTC QLQ-INFO25 questionnaire: A prospective multicentric study.

Bozec A, Schultz P, Gal J, Chamorey E, Chateau Y, Dassonville O, Poissonnet G, Santini J, Peyrade F, Saada E, Guigay J, Benezery K, Leysalle A, Santini L, Giovanni A, Messaoudi L, Fakhry N.

Eur J Cancer. 2016 Nov;67:73-82. doi: 10.1016/j.ejca.2016.08.005. Epub 2016 Sep 9.


Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer.

Bozec A, Ebran N, Radosevic-Robin N, Chamorey E, Yahia HB, Marcie S, Gautier M, Penault-Llorca F, Milano G.

Head Neck. 2017 Jan;39(1):151-159. doi: 10.1002/hed.24560. Epub 2016 Aug 10.


Primary radical ablative surgery and fibula free-flap reconstruction for T4 oral cavity squamous cell carcinoma with mandibular invasion: oncologic and functional results and their predictive factors.

Camuzard O, Dassonville O, Ettaiche M, Chamorey E, Poissonnet G, Berguiga R, Leysalle A, Benezery K, Peyrade F, Saada E, Hechema R, Sudaka A, Haudebourg J, Demard F, Santini J, Bozec A.

Eur Arch Otorhinolaryngol. 2017 Jan;274(1):441-449. doi: 10.1007/s00405-016-4219-7. Epub 2016 Jul 20.


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