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Items: 1 to 50 of 51

1.

Muco-Obstructive Lung Diseases.

Boyton RJ, Altmann DM.

N Engl J Med. 2019 Sep 5;381(10):e20. doi: 10.1056/NEJMc1907962. No abstract available.

PMID:
31483985
2.

Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C.

Sim MJW, Rajagopalan S, Altmann DM, Boyton RJ, Sun PD, Long EO.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12964-12973. doi: 10.1073/pnas.1903781116. Epub 2019 May 28.

3.

Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial.

Chambers ES, Byrne CS, Morrison DJ, Murphy KG, Preston T, Tedford C, Garcia-Perez I, Fountana S, Serrano-Contreras JI, Holmes E, Reynolds CJ, Roberts JF, Boyton RJ, Altmann DM, McDonald JAK, Marchesi JR, Akbar AN, Riddell NE, Wallis GA, Frost GS.

Gut. 2019 Aug;68(8):1430-1438. doi: 10.1136/gutjnl-2019-318424. Epub 2019 Apr 10.

4.

Bioluminescent Reporting of In Vivo IFN-γ Immune Responses during Infection and Autoimmunity.

Reynolds CJ, Chong DLW, Li Y, Black SL, Cutler A, Webster Z, Manji J, Altmann DM, Boyton RJ.

J Immunol. 2019 Apr 15;202(8):2502-2510. doi: 10.4049/jimmunol.1801453. Epub 2019 Feb 27.

5.

Lung Defense through IL-8 Carries a Cost of Chronic Lung Remodeling and Impaired Function.

Reynolds CJ, Quigley K, Cheng X, Suresh A, Tahir S, Ahmed-Jushuf F, Nawab K, Choy K, Walker SA, Mathie SA, Sim M, Stowell J, Manji J, Pollard T, Altmann DM, Boyton RJ.

Am J Respir Cell Mol Biol. 2018 Nov;59(5):557-571. doi: 10.1165/rcmb.2018-0007OC.

6.

Immune Control of Burkholderia pseudomallei--Common, High-Frequency T-Cell Responses to a Broad Repertoire of Immunoprevalent Epitopes.

Nithichanon A, Rinchai D, Buddhisa S, Saenmuang P, Kewcharoenwong C, Kessler B, Khaenam P, Chetchotisakd P, Maillere B, Robinson J, Reynolds CJ, Boyton RJ, Altmann DM, Lertmemongkolchai G.

Front Immunol. 2018 Mar 20;9:484. doi: 10.3389/fimmu.2018.00484. eCollection 2018.

7.

T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses.

Reynolds CJ, Suleyman OM, Ortega-Prieto AM, Skelton JK, Bonnesoeur P, Blohm A, Carregaro V, Silva JS, James EA, Maillère B, Dorner M, Boyton RJ, Altmann DM.

Sci Rep. 2018 Jan 12;8(1):672. doi: 10.1038/s41598-017-18781-1.

8.

Infection with Burkholderia pseudomallei - immune correlates of survival in acute melioidosis.

Dunachie SJ, Jenjaroen K, Reynolds CJ, Quigley KJ, Sergeant R, Sumonwiriya M, Chaichana P, Chumseng S, Ariyaprasert P, Lassaux P, Gourlay L, Promwong C, Teparrukkul P, Limmathurotsakul D, Day NPJ, Altmann DM, Boyton RJ.

Sci Rep. 2017 Sep 22;7(1):12143. doi: 10.1038/s41598-017-12331-5.

9.

Guillain-Barré syndrome and arboviral infection in Brazil.

Keesen TSL, de Almeida RP, Gois BM, Peixoto RF, Pachá ASC, Vieira FCF, Paixão M, Cazzaniga R, Boyton RJ, Altmann DM.

Lancet Infect Dis. 2017 Jul;17(7):693-694. doi: 10.1016/S1473-3099(17)30333-X. Epub 2017 Jun 21. No abstract available.

10.

Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C.

Sim MJ, Malaker SA, Khan A, Stowell JM, Shabanowitz J, Peterson ME, Rajagopalan S, Hunt DF, Altmann DM, Long EO, Boyton RJ.

Front Immunol. 2017 Mar 14;8:193. doi: 10.3389/fimmu.2017.00193. eCollection 2017.

11.

Bronchiectasis: Current Concepts in Pathogenesis, Immunology, and Microbiology.

Boyton RJ, Altmann DM.

Annu Rev Pathol. 2016 May 23;11:523-54. doi: 10.1146/annurev-pathol-012615-044344. Epub 2016 Mar 2. Review.

PMID:
26980162
12.

BIITE: A Tool to Determine HLA Class II Epitopes from T Cell ELISpot Data.

Boelen L, O'Neill PK, Quigley KJ, Reynolds CJ, Maillere B, Robinson JH, Lertmemongkolchai G, Altmann DM, Boyton RJ, Asquith B.

PLoS Comput Biol. 2016 Mar 8;12(3):e1004796. doi: 10.1371/journal.pcbi.1004796. eCollection 2016 Mar.

13.

CD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor.

Ascough S, Ingram RJ, Chu KK, Musson JA, Moore SJ, Gallagher T, Baillie L, Williamson ED, Robinson JH, Maillere B, Boyton RJ, Altmann DM.

Front Microbiol. 2016 Jan 5;6:1506. doi: 10.3389/fmicb.2015.01506. eCollection 2015.

14.

KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells.

Sim MJ, Stowell J, Sergeant R, Altmann DM, Long EO, Boyton RJ.

Eur J Immunol. 2016 Jan;46(1):185-91. doi: 10.1002/eji.201545757. Epub 2015 Nov 2.

15.

Natural cutaneous anthrax infection, but not vaccination, induces a CD4(+) T cell response involving diverse cytokines.

Ingram RJ, Ascough S, Reynolds CJ, Metan G, Doganay M, Baillie L, Williamson DE, Robinson JH, Maillere B, Boyton RJ, Altmann DM.

Cell Biosci. 2015 Apr 26;5:20. doi: 10.1186/s13578-015-0011-4. eCollection 2015.

16.

Autoantigen cross-reactive environmental antigen can trigger multiple sclerosis-like disease.

Reynolds CJ, Sim MJ, Quigley KJ, Altmann DM, Boyton RJ.

J Neuroinflammation. 2015 May 13;12:91. doi: 10.1186/s12974-015-0313-9.

17.

MS in South Asians in England: early disease onset and novel pattern of myelin autoimmunity.

Nicholas RS, Kostadima V, Hanspal M, Wakerley BR, Sergeant R, Decuypere S, Malik O, Boyton RJ, Altmann DM.

BMC Neurol. 2015 May 3;15:72. doi: 10.1186/s12883-015-0324-2.

18.

Chronic Infection by Mucoid Pseudomonas aeruginosa Associated with Dysregulation in T-Cell Immunity to Outer Membrane Porin F.

Quigley KJ, Reynolds CJ, Goudet A, Raynsford EJ, Sergeant R, Quigley A, Worgall S, Bilton D, Wilson R, Loebinger MR, Maillere B, Altmann DM, Boyton RJ.

Am J Respir Crit Care Med. 2015 Jun 1;191(11):1250-64. doi: 10.1164/rccm.201411-1995OC.

19.

CD4+ T cell epitopes of FliC conserved between strains of Burkholderia: implications for vaccines against melioidosis and cepacia complex in cystic fibrosis.

Musson JA, Reynolds CJ, Rinchai D, Nithichanon A, Khaenam P, Favry E, Spink N, Chu KK, De Soyza A, Bancroft GJ, Lertmemongkolchai G, Maillere B, Boyton RJ, Altmann DM, Robinson JH.

J Immunol. 2014 Dec 15;193(12):6041-9. doi: 10.4049/jimmunol.1402273. Epub 2014 Nov 12.

20.

The serodominant secreted effector protein of Salmonella, SseB, is a strong CD4 antigen containing an immunodominant epitope presented by diverse HLA class II alleles.

Reynolds CJ, Jones C, Blohmke CJ, Darton TC, Goudet A, Sergeant R, Maillere B, Pollard AJ, Altmann DM, Boyton RJ.

Immunology. 2014 Nov;143(3):438-46. doi: 10.1111/imm.12327.

21.

Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4+ T cell immunity.

Ascough S, Ingram RJ, Chu KK, Reynolds CJ, Musson JA, Doganay M, Metan G, Ozkul Y, Baillie L, Sriskandan S, Moore SJ, Gallagher TB, Dyson H, Williamson ED, Robinson JH, Maillere B, Boyton RJ, Altmann DM.

PLoS Pathog. 2014 May 1;10(5):e1004085. doi: 10.1371/journal.ppat.1004085. eCollection 2014 May.

22.

Injectional anthrax infection due to heroin use induces strong immunological memory.

Ascough S, Ingram RJ, Abarra A, Holmes AJ, Maillere B, Altmann DM, Boyton RJ.

J Infect. 2014 Feb;68(2):200-3. No abstract available.

23.

Peptide-induced immune regulation by a promiscuous and immunodominant CD4T-cell epitope of Timothy grass pollen: a role of Cbl-b and Itch in regulation.

Till SJ, Raynsford EJ, Reynolds CJ, Quigley KJ, Grzybowska-Kowalczyk A, Saggar LR, Goldstone A, Maillere B, Kwok WW, Altmann DM, Durham SR, Boyton RJ.

Thorax. 2014 Apr;69(4):335-45. doi: 10.1136/thoraxjnl-2013-204324. Epub 2013 Nov 20.

24.

Th1 not Th17 cells drive spontaneous MS-like disease despite a functional regulatory T cell response.

Lowther DE, Chong DL, Ascough S, Ettorre A, Ingram RJ, Boyton RJ, Altmann DM.

Acta Neuropathol. 2013 Oct;126(4):501-15. doi: 10.1007/s00401-013-1159-9. Epub 2013 Aug 10.

PMID:
23934116
25.

Immune mechanisms and the impact of the disrupted lung microbiome in chronic bacterial lung infection and bronchiectasis.

Boyton RJ, Reynolds CJ, Quigley KJ, Altmann DM.

Clin Exp Immunol. 2013 Feb;171(2):117-23. doi: 10.1111/cei.12003. Review.

26.

Immune regulation in idiopathic bronchiectasis.

Boyton RJ, Altmann DM.

Ann N Y Acad Sci. 2012 Dec;1272:68-72. doi: 10.1111/j.1749-6632.2012.06756.x.

PMID:
23231716
27.

Increased HLA-E expression in white matter lesions in multiple sclerosis.

Durrenberger PF, Webb LV, Sim MJ, Nicholas RS, Altmann DM, Boyton RJ.

Immunology. 2012 Dec;137(4):317-25. doi: 10.1111/imm.12012.

28.

Diverse approaches to analysing the history of human and pathogen evolution: how to tell the story of the past 70 000 years.

Altmann DM, Balloux F, Boyton RJ.

Philos Trans R Soc Lond B Biol Sci. 2012 Mar 19;367(1590):765-9. doi: 10.1098/rstb.2011.0318.

29.

Innate immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1).

Durrenberger PF, Ettorre A, Kamel F, Webb LV, Sim M, Nicholas RS, Malik O, Reynolds R, Boyton RJ, Altmann DM.

J Neuroinflammation. 2012 Jan 2;9:1. doi: 10.1186/1742-2094-9-1.

30.

Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression.

Campbell JD, Buckland KF, McMillan SJ, Kearley J, Oldfield WL, Stern LJ, Grönlund H, van Hage M, Reynolds CJ, Boyton RJ, Cobbold SP, Kay AB, Altmann DM, Lloyd CM, Larché M.

J Exp Med. 2009 Jul 6;206(7):1535-47. doi: 10.1084/jem.20082901. Epub 2009 Jun 15.

31.

A role of cellular prion protein in programming T-cell cytokine responses in disease.

Ingram RJ, Isaacs JD, Kaur G, Lowther DE, Reynolds CJ, Boyton RJ, Collinge J, Jackson GS, Altmann DM.

FASEB J. 2009 Jun;23(6):1672-84. doi: 10.1096/fj.08-116087. Epub 2009 Feb 9.

PMID:
19204074
32.

Regulation of immunity in bronchiectasis.

Boyton RJ.

Med Mycol. 2009;47 Suppl 1:S175-82. doi: 10.1080/13693780802163370. Epub 2008 Jun 4. Review.

PMID:
18608925
33.

Human leucocyte antigen class II association in idiopathic bronchiectasis, a disease of chronic lung infection, implicates a role for adaptive immunity.

Boyton RJ, Smith J, Jones M, Reynolds C, Ozerovitch L, Chaudhry A, Wilson R, Rose M, Altmann DM.

Clin Exp Immunol. 2008 Apr;152(1):95-101. doi: 10.1111/j.1365-2249.2008.03596.x. Epub 2008 Jan 28.

34.

Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease.

Boyton RJ, Altmann DM.

Clin Exp Immunol. 2007 Jul;149(1):1-8. Epub 2007 May 22. Review.

35.

IFN gamma and CXCR-1 gene polymorphisms in idiopathic bronchiectasis.

Boyton RJ, Reynolds C, Wahid FN, Jones MG, Ozerovitch L, Ahmad T, Chaudhry A, Jewell DP, Kon OM, Smith J, Rose M, Newman-Taylor AJ, Cole P, Wilson R, Altmann DM.

Tissue Antigens. 2006 Oct;68(4):325-30.

PMID:
17026468
36.

Effect of tolerance induction to immunodominant T-cell epitopes of Sendai virus on gene expression following repeat administration to lung.

Griesenbach U, Boyton RJ, Somerton L, Garcia SE, Ferrari S, Owaki T, Ya-Fen Z, Geddes DM, Hasegawa M, Altmann DM, Alton EW.

Gene Ther. 2006 Mar;13(5):449-56.

PMID:
16319950
37.

HLA-C and killer cell immunoglobulin-like receptor genes in idiopathic bronchiectasis.

Boyton RJ, Smith J, Ward R, Jones M, Ozerovitch L, Wilson R, Rose M, Trowsdale J, Altmann DM.

Am J Respir Crit Care Med. 2006 Feb 1;173(3):327-33. Epub 2005 Oct 27.

PMID:
16254274
38.

Pulmonary infection with Cryptococcus neoformans in the face of underlying sarcoidosis.

Boyton RJ, Altmann DM, Wright A, Kon OM.

Respiration. 2007;74(4):462-6. Epub 2005 Aug 11.

PMID:
16106116
39.

Stat4-null non-obese diabetic mice: protection from diabetes and experimental allergic encephalomyelitis, but with concomitant epitope spread.

Boyton RJ, Davies S, Marden C, Fantino C, Reynolds C, Portugal K, Dewchand H, Altmann DM.

Int Immunol. 2005 Sep;17(9):1157-65. Epub 2005 Jul 18.

PMID:
16027138
40.

Infectious lung complications in patients with HIV/AIDS.

Boyton RJ.

Curr Opin Pulm Med. 2005 May;11(3):203-7. Review.

PMID:
15818180
41.

High incidence of spontaneous disease in an HLA-DR15 and TCR transgenic multiple sclerosis model.

Ellmerich S, Mycko M, Takacs K, Waldner H, Wahid FN, Boyton RJ, King RH, Smith PA, Amor S, Herlihy AH, Hewitt RE, Jutton M, Price DA, Hafler DA, Kuchroo VK, Altmann DM.

J Immunol. 2005 Feb 15;174(4):1938-46.

42.

Disease-related epitope spread in a humanized T cell receptor transgenic model of multiple sclerosis.

Ellmerich S, Takacs K, Mycko M, Waldner H, Wahid F, Boyton RJ, Smith PA, Amor S, Baker D, Hafler DA, Kuchroo VK, Altmann DM.

Eur J Immunol. 2004 Jul;34(7):1839-48.

43.

Asthma: new developments in cytokine regulation.

Boyton RJ, Altmann DM.

Clin Exp Immunol. 2004 Apr;136(1):13-4. No abstract available.

44.

The pulmonary physician in critical care * Illustrative case 5: HIV associated pneumonia.

Boyton RJ, Mitchell DM, Kon OM.

Thorax. 2003 Aug;58(8):721-5. Review. No abstract available.

45.

Reciprocal conditioning: T cells as regulators of dendritic cell function.

Altmann DM, Boyton RJ.

Immunology. 2003 Aug;109(4):473-5. No abstract available.

46.

Is selection for TCR affinity a factor in cytokine polarization?

Boyton RJ, Altmann DM.

Trends Immunol. 2002 Nov;23(11):526-9.

PMID:
12401404
47.

Pulmonary defences to acute respiratory infection.

Boyton RJ, Openshaw PJ.

Br Med Bull. 2002;61:1-12. Review.

PMID:
11997295
48.

Transgenic models of autoimmune disease.

Boyton RJ, Altmann DM.

Clin Exp Immunol. 2002 Jan;127(1):4-11. Review.

49.
50.

Glutamic acid decarboxylase T lymphocyte responses associated with susceptibility or resistance to type I diabetes: analysis in disease discordant human twins, non-obese diabetic mice and HLA-DQ transgenic mice.

Boyton RJ, Lohmann T, Londei M, Kalbacher H, Halder T, Frater AJ, Douek DC, Leslie DG, Flavell RA, Altmann DM.

Int Immunol. 1998 Dec;10(12):1765-76.

PMID:
9885897

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