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Items: 1 to 50 of 168

1.

Permeabilised skeletal muscle reveals mitochondrial deficiency in malignant hyperthermia-susceptible individuals.

Chang L, Daly C, Miller DM, Allen PD, Boyle JP, Hopkins PM, Shaw MA.

Br J Anaesth. 2019 May;122(5):613-621. doi: 10.1016/j.bja.2019.02.010. Epub 2019 Mar 20.

PMID:
30916033
2.
3.

Effector variation at tandem gene arrays in tissue-dwelling coccidia: who needs antigenic variation anyway?

Blank ML, Boyle JP.

Curr Opin Microbiol. 2018 Dec;46:86-92. doi: 10.1016/j.mib.2018.09.001. Epub 2018 Oct 11. Review.

PMID:
30317151
4.

Quercetin preserves redox status and stimulates mitochondrial function in metabolically-stressed HepG2 cells.

Houghton MJ, Kerimi A, Tumova S, Boyle JP, Williamson G.

Free Radic Biol Med. 2018 Dec;129:296-309. doi: 10.1016/j.freeradbiomed.2018.09.037. Epub 2018 Sep 25.

PMID:
30266680
5.

Dissection of the in vitro developmental program of Hammondia hammondi reveals a link between stress sensitivity and life cycle flexibility in Toxoplasma gondii.

Sokol SL, Primack AS, Nair SC, Wong ZS, Tembo M, Verma SK, Cerqueira-Cezar CK, Dubey JP, Boyle JP.

Elife. 2018 May 22;7. pii: e36491. doi: 10.7554/eLife.36491.

6.

A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions.

Blank ML, Parker ML, Ramaswamy R, Powell CJ, English ED, Adomako-Ankomah Y, Pernas LF, Workman SD, Boothroyd JC, Boulanger MJ, Boyle JP.

Mol Microbiol. 2018 Jun;108(5):519-535. doi: 10.1111/mmi.13947. Epub 2018 Apr 11.

7.

Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines.

Ander SE, Rudzki EN, Arora N, Sadovsky Y, Coyne CB, Boyle JP.

MBio. 2018 Jan 9;9(1). pii: e01678-17. doi: 10.1128/mBio.01678-17.

8.

Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K+ channel Kv1.5.

Al-Owais MM, Hettiarachchi NT, Boyle JP, Scragg JL, Elies J, Dallas ML, Lippiat JD, Steele DS, Peers C.

Cell Death Dis. 2017 Nov 2;8(11):e3163. doi: 10.1038/cddis.2017.568.

9.

A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K+ channels in carbon monoxide-induced proarrhythmic early afterdepolarizations.

Al-Owais MM, Hettiarachchi NT, Kirton HM, Hardy ME, Boyle JP, Scragg JL, Steele DS, Peers C.

FASEB J. 2017 Nov;31(11):4845-4854. doi: 10.1096/fj.201700259R. Epub 2017 Jul 25.

10.

Heme oxygenase-1 derived carbon monoxide suppresses Aβ1-42 toxicity in astrocytes.

Hettiarachchi NT, Boyle JP, Dallas ML, Al-Owais MM, Scragg JL, Peers C.

Cell Death Dis. 2017 Jun 15;8(6):e2884. doi: 10.1038/cddis.2017.276.

11.

TgPRELID, a Mitochondrial Protein Linked to Multidrug Resistance in the Parasite Toxoplasma gondii.

Jeffers V, Kamau ET, Srinivasan AR, Harper J, Sankaran P, Post SE, Varberg JM, Sullivan WJ Jr, Boyle JP.

mSphere. 2017 Feb 1;2(1). pii: e00229-16. doi: 10.1128/mSphere.00229-16. eCollection 2017 Jan-Feb.

12.

A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance.

McConkey CA, Delorme-Axford E, Nickerson CA, Kim KS, Sadovsky Y, Boyle JP, Coyne CB.

Sci Adv. 2016 Mar 4;2(3):e1501462. doi: 10.1126/sciadv.1501462. eCollection 2016 Mar.

13.

Host Mitochondrial Association Evolved in the Human Parasite Toxoplasma gondii via Neofunctionalization of a Gene Duplicate.

Adomako-Ankomah Y, English ED, Danielson JJ, Pernas LF, Parker ML, Boulanger MJ, Dubey JP, Boyle JP.

Genetics. 2016 May;203(1):283-98. doi: 10.1534/genetics.115.186270. Epub 2016 Feb 26.

14.

Regulation of the T-type Ca(2+) channel Cav3.2 by hydrogen sulfide: emerging controversies concerning the role of H2 S in nociception.

Elies J, Scragg JL, Boyle JP, Gamper N, Peers C.

J Physiol. 2016 Aug 1;594(15):4119-29. doi: 10.1113/JP270963. Epub 2016 Feb 25. Review.

15.

Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes.

Lorenzi H, Khan A, Behnke MS, Namasivayam S, Swapna LS, Hadjithomas M, Karamycheva S, Pinney D, Brunk BP, Ajioka JW, Ajzenberg D, Boothroyd JC, Boyle JP, Dardé ML, Diaz-Miranda MA, Dubey JP, Fritz HM, Gennari SM, Gregory BD, Kim K, Saeij JP, Su C, White MW, Zhu XQ, Howe DK, Rosenthal BM, Grigg ME, Parkinson J, Liu L, Kissinger JC, Roos DS, Sibley LD.

Nat Commun. 2016 Jan 7;7:10147. doi: 10.1038/ncomms10147.

16.

Medial tibial "spackling" to lessen chronic medial tibial soft tissue irritation.

Martin JR, Watters TS, Levy DL, Jennings JM, Boyle JP, Dennis DA.

Arthroplast Today. 2016 Jul 2;2(3):111-115. doi: 10.1016/j.artd.2016.05.003. eCollection 2016 Sep.

17.

The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway.

Yang Z, Kirton HM, MacDougall DA, Boyle JP, Deuchars J, Frater B, Ponnambalam S, Hardy ME, White E, Calaghan SC, Peers C, Steele DS.

Sci Signal. 2015 Oct 13;8(398):ra101. doi: 10.1126/scisignal.aaa7677.

18.

Inhibition of T-type Ca2+ Channels by Hydrogen Sulfide.

Elies J, Scragg JL, Dallas ML, Huang D, Huang S, Boyle JP, Gamper N, Peers C.

Adv Exp Med Biol. 2015;860:353-60. doi: 10.1007/978-3-319-18440-1_40.

PMID:
26303500
19.

Heme Oxygenase-1 Influences Apoptosis via CO-mediated Inhibition of K+ Channels.

Al-Owais MM, Dallas ML, Boyle JP, Scragg JL, Peers C.

Adv Exp Med Biol. 2015;860:343-51. doi: 10.1007/978-3-319-18440-1_39.

PMID:
26303499
20.

T-Type Ca2+ Channel Regulation by CO: A Mechanism for Control of Cell Proliferation.

Duckles H, Al-Owais MM, Elies J, Johnson E, Boycott HE, Dallas ML, Porter KE, Boyle JP, Scragg JL, Peers C.

Adv Exp Med Biol. 2015;860:291-300. doi: 10.1007/978-3-319-18440-1_33.

PMID:
26303493
21.

H2S does not regulate proliferation via T-type Ca2+ channels.

Elies J, Johnson E, Boyle JP, Scragg JL, Peers C.

Biochem Biophys Res Commun. 2015 Jun 12;461(4):659-64. doi: 10.1016/j.bbrc.2015.04.087. Epub 2015 Apr 24.

22.

International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease.

Bryant CE, Orr S, Ferguson B, Symmons MF, Boyle JP, Monie TP.

Pharmacol Rev. 2015;67(2):462-504. doi: 10.1124/pr.114.009928. Review.

23.

Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators.

Workman DG, Tsatsanis A, Lewis FW, Boyle JP, Mousadoust M, Hettiarachchi NT, Hunter M, Peers CS, Tétard D, Duce JA.

Metallomics. 2015 May;7(5):867-76. doi: 10.1039/c4mt00326h. Epub 2015 Mar 17.

24.

New method for the orthogonal labeling and purification of Toxoplasma gondii proteins while inside the host cell.

Wier GM, McGreevy EM, Brown MJ, Boyle JP.

MBio. 2015 Mar 10;6(2):e01628. doi: 10.1128/mBio.01628-14.

25.

Secreted effectors in Toxoplasma gondii and related species: determinants of host range and pathogenesis?

English ED, Adomako-Ankomah Y, Boyle JP.

Parasite Immunol. 2015 Mar;37(3):127-40. doi: 10.1111/pim.12166. Review.

26.

Insights into the molecular basis of the NOD2 signalling pathway.

Boyle JP, Parkhouse R, Monie TP.

Open Biol. 2014 Dec;4(12). pii: 140178. doi: 10.1098/rsob.140178. Review.

27.

Oxidative modulation of K+ channels in the central nervous system in neurodegenerative diseases and aging.

Peers C, Boyle JP.

Antioxid Redox Signal. 2015 Feb 20;22(6):505-21. doi: 10.1089/ars.2014.6007. Epub 2014 Dec 4. Review.

28.

Hammondia hammondi harbors functional orthologs of the host-modulating effectors GRA15 and ROP16 but is distinguished from Toxoplasma gondii by a unique transcriptional profile.

Walzer KA, Wier GM, Dam RA, Srinivasan AR, Borges AL, English ED, Herrmann DC, Schares G, Dubey JP, Boyle JP.

Eukaryot Cell. 2014 Dec;13(12):1507-18. doi: 10.1128/EC.00215-14. Epub 2014 Oct 3.

29.

Hydrogen sulfide inhibits Cav3.2 T-type Ca2+ channels.

Elies J, Scragg JL, Huang S, Dallas ML, Huang D, MacDougall D, Boyle JP, Gamper N, Peers C.

FASEB J. 2014 Dec;28(12):5376-87. doi: 10.1096/fj.14-257113. Epub 2014 Sep 2.

PMID:
25183670
30.

Human trophoblasts confer resistance to viruses implicated in perinatal infection.

Bayer A, Delorme-Axford E, Sleigher C, Frey TK, Trobaugh DW, Klimstra WB, Emert-Sedlak LA, Smithgall TE, Kinchington PR, Vadia S, Seveau S, Boyle JP, Coyne CB, Sadovsky Y.

Am J Obstet Gynecol. 2015 Jan;212(1):71.e1-71.e8. doi: 10.1016/j.ajog.2014.07.060. Epub 2014 Aug 6.

31.

Blau syndrome polymorphisms in NOD2 identify nucleotide hydrolysis and helical domain 1 as signalling regulators.

Parkhouse R, Boyle JP, Monie TP.

FEBS Lett. 2014 Sep 17;588(18):3382-9. doi: 10.1016/j.febslet.2014.07.029. Epub 2014 Aug 2.

32.

Type II Toxoplasma gondii induction of CD40 on infected macrophages enhances interleukin-12 responses.

Morgado P, Sudarshana DM, Gov L, Harker KS, Lam T, Casali P, Boyle JP, Lodoen MB.

Infect Immun. 2014 Oct;82(10):4047-55. doi: 10.1128/IAI.01615-14. Epub 2014 Jul 14.

33.

Interaction between NOD2 and CARD9 involves the NOD2 NACHT and the linker region between the NOD2 CARDs and NACHT domain.

Parkhouse R, Boyle JP, Mayle S, Sawmynaden K, Rittinger K, Monie TP.

FEBS Lett. 2014 Aug 25;588(17):2830-6. doi: 10.1016/j.febslet.2014.06.035. Epub 2014 Jun 21.

34.

Engagement of nucleotide-binding oligomerization domain-containing protein 1 (NOD1) by receptor-interacting protein 2 (RIP2) is insufficient for signal transduction.

Mayle S, Boyle JP, Sekine E, Zurek B, Kufer TA, Monie TP.

J Biol Chem. 2014 Aug 15;289(33):22900-14. doi: 10.1074/jbc.M114.557900. Epub 2014 Jun 23.

35.

Diverse mechanisms underlying the regulation of ion channels by carbon monoxide.

Peers C, Boyle JP, Scragg JL, Dallas ML, Al-Owais MM, Hettiarachichi NT, Elies J, Johnson E, Gamper N, Steele DS.

Br J Pharmacol. 2015 Mar;172(6):1546-56. doi: 10.1111/bph.12760. Epub 2014 Jul 2. Review.

36.

Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response.

Pernas L, Adomako-Ankomah Y, Shastri AJ, Ewald SE, Treeck M, Boyle JP, Boothroyd JC.

PLoS Biol. 2014 Apr 29;12(4):e1001845. doi: 10.1371/journal.pbio.1001845. eCollection 2014 Apr.

37.

Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca2+ channels.

Duckles H, Boycott HE, Al-Owais MM, Elies J, Johnson E, Dallas ML, Porter KE, Giuntini F, Boyle JP, Scragg JL, Peers C.

Pflugers Arch. 2015 Feb;467(2):415-27. doi: 10.1007/s00424-014-1503-5. Epub 2014 Apr 18.

38.

Inhibition of the cardiac Na⁺ channel Nav1.5 by carbon monoxide.

Elies J, Dallas ML, Boyle JP, Scragg JL, Duke A, Steele DS, Peers C.

J Biol Chem. 2014 Jun 6;289(23):16421-9. doi: 10.1074/jbc.M114.569996. Epub 2014 Apr 9.

39.

Continuum approaches to understanding ion and peptide interactions with the membrane.

Latorraca NR, Callenberg KM, Boyle JP, Grabe M.

J Membr Biol. 2014 May;247(5):395-408. doi: 10.1007/s00232-014-9646-z. Epub 2014 Mar 21.

40.

Differential locus expansion distinguishes Toxoplasmatinae species and closely related strains of Toxoplasma gondii.

Adomako-Ankomah Y, Wier GM, Borges AL, Wand HE, Boyle JP.

MBio. 2014 Feb 4;5(1):e01003-13. doi: 10.1128/mBio.01003-13.

41.

Comparative Genomic and Sequence Analysis Provides Insight into the Molecular Functionality of NOD1 and NOD2.

Boyle JP, Mayle S, Parkhouse R, Monie TP.

Front Immunol. 2013 Oct 7;4:317. doi: 10.3389/fimmu.2013.00317. eCollection 2013.

42.

Modeling the impact of prevention policies on future diabetes prevalence in the United States: 2010-2030.

Gregg EW, Boyle JP, Thompson TJ, Barker LE, Albright AL, Williamson DF.

Popul Health Metr. 2013 Sep 18;11(1):18. doi: 10.1186/1478-7954-11-18.

43.

Small area variation in diabetes prevalence in Puerto Rico.

Tierney EF, Burrows NR, Barker LE, Beckles GL, Boyle JP, Cadwell BL, Kirtland KA, Thompson TJ.

Rev Panam Salud Publica. 2013 Jun;33(6):398-406.

44.

Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite.

Feliu V, Vasseur V, Grover HS, Chu HH, Brown MJ, Wang J, Boyle JP, Robey EA, Shastri N, Blanchard N.

PLoS Pathog. 2013;9(6):e1003449. doi: 10.1371/journal.ppat.1003449. Epub 2013 Jun 20.

45.

Carbon monoxide inhibition of Cav3.2 T-type Ca2+ channels reveals tonic modulation by thioredoxin.

Boycott HE, Dallas ML, Elies J, Pettinger L, Boyle JP, Scragg JL, Gamper N, Peers C.

FASEB J. 2013 Aug;27(8):3395-407. doi: 10.1096/fj.13-227249. Epub 2013 May 13.

PMID:
23671274
46.

Hammondia hammondi, an avirulent relative of Toxoplasma gondii, has functional orthologs of known T. gondii virulence genes.

Walzer KA, Adomako-Ankomah Y, Dam RA, Herrmann DC, Schares G, Dubey JP, Boyle JP.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7446-51. doi: 10.1073/pnas.1304322110. Epub 2013 Apr 15.

47.

Bayesian Small Area Estimates of Diabetes Incidence by United States County, 2009.

Barker LE, Thompson TJ, Kirtland KA, Boyle JP, Geiss LS, McCauley MM, Albright AL.

J Data Sci. 2013 Apr;11(1):269-280.

48.

Cell swelling and the NLRP3 inflammasome.

Boyle JP, Bryant CE, Monie TP.

Immunity. 2013 Mar 21;38(3):399. doi: 10.1016/j.immuni.2013.02.006. No abstract available.

49.

Molecular and biological characterization of first isolates of Hammondia hammondi from cats from Ethiopia.

Dubey JP, Tilahun G, Boyle JP, Schares G, Verma SK, Ferreira LR, Oliveira S, Tiao N, Darrington C, Gebreyes WA.

J Parasitol. 2013 Aug;99(4):614-8. doi: 10.1645/12-51.1. Epub 2013 Mar 21.

PMID:
23517380
50.

VennPlex--a novel Venn diagram program for comparing and visualizing datasets with differentially regulated datapoints.

Cai H, Chen H, Yi T, Daimon CM, Boyle JP, Peers C, Maudsley S, Martin B.

PLoS One. 2013;8(1):e53388. doi: 10.1371/journal.pone.0053388. Epub 2013 Jan 7.

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