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Items: 44

1.

Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B cell Responses to Influenza Hemagglutinin.

Andrews SF, Chambers MJ, Schramm CA, Plyler J, Raab JE, Kanekiyo M, Gillespie RA, Ransier A, Darko S, Hu J, Chen X, Yassine HM, Boyington JC, Crank MC, Chen GL, Coates E, Mascola JR, Douek DC, Graham BS, Ledgerwood JE, McDermott AB.

Immunity. 2019 Aug 20;51(2):398-410.e5. doi: 10.1016/j.immuni.2019.06.024. Epub 2019 Jul 23.

PMID:
31350180
2.

Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages.

Corbett KS, Moin SM, Yassine HM, Cagigi A, Kanekiyo M, Boyoglu-Barnum S, Myers SI, Tsybovsky Y, Wheatley AK, Schramm CA, Gillespie RA, Shi W, Wang L, Zhang Y, Andrews SF, Joyce MG, Crank MC, Douek DC, McDermott AB, Mascola JR, Graham BS, Boyington JC.

MBio. 2019 Feb 26;10(1). pii: e02810-18. doi: 10.1128/mBio.02810-18.

3.

Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies.

Duan H, Chen X, Boyington JC, Cheng C, Zhang Y, Jafari AJ, Stephens T, Tsybovsky Y, Kalyuzhniy O, Zhao P, Menis S, Nason MC, Normandin E, Mukhamedova M, DeKosky BJ, Wells L, Schief WR, Tian M, Alt FW, Kwong PD, Mascola JR.

Immunity. 2018 Aug 21;49(2):301-311.e5. doi: 10.1016/j.immuni.2018.07.005. Epub 2018 Jul 31.

PMID:
30076101
4.

Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera.

Yassine HM, McTamney PM, Boyington JC, Ruckwardt TJ, Crank MC, Smatti MK, Ledgerwood JE, Graham BS.

Sci Rep. 2018 Jun 5;8(1):8628. doi: 10.1038/s41598-018-26538-7.

5.

Protection of calves by a prefusion-stabilized bovine RSV F vaccine.

Zhang B, Chen L, Silacci C, Thom M, Boyington JC, Druz A, Joyce MG, Guzman E, Kong WP, Lai YT, Stewart-Jones GBE, Tsybovsky Y, Yang Y, Zhou T, Baxa U, Mascola JR, Corti D, Lanzavecchia A, Taylor G, Kwong PD.

NPJ Vaccines. 2017 Mar 8;2:7. doi: 10.1038/s41541-017-0005-9.

6.

Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans.

Andrews SF, Joyce MG, Chambers MJ, Gillespie RA, Kanekiyo M, Leung K, Yang ES, Tsybovsky Y, Wheatley AK, Crank MC, Boyington JC, Prabhakaran MS, Narpala SR, Chen X, Bailer RT, Chen G, Coates E, Kwong PD, Koup RA, Mascola JR, Graham BS, Ledgerwood JE, McDermott AB.

Sci Immunol. 2017 Jul 14;2(13). pii: eaan2676. doi: 10.1126/sciimmunol.aan2676.

PMID:
28783708
7.

Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus.

Boyington JC, Joyce MG, Sastry M, Stewart-Jones GB, Chen M, Kong WP, Ngwuta JO, Thomas PV, Tsybovsky Y, Yang Y, Zhang B, Chen L, Druz A, Georgiev IS, Ko K, Zhou T, Mascola JR, Graham BS, Kwong PD.

PLoS One. 2016 Jul 27;11(7):e0159709. doi: 10.1371/journal.pone.0159709. eCollection 2016.

8.

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.

Joyce MG, Wheatley AK, Thomas PV, Chuang GY, Soto C, Bailer RT, Druz A, Georgiev IS, Gillespie RA, Kanekiyo M, Kong WP, Leung K, Narpala SN, Prabhakaran MS, Yang ES, Zhang B, Zhang Y, Asokan M, Boyington JC, Bylund T, Darko S, Lees CR, Ransier A, Shen CH, Wang L, Whittle JR, Wu X, Yassine HM, Santos C, Matsuoka Y, Tsybovsky Y, Baxa U; NISC Comparative Sequencing Program, Mullikin JC, Subbarao K, Douek DC, Graham BS, Koup RA, Ledgerwood JE, Roederer M, Shapiro L, Kwong PD, Mascola JR, McDermott AB.

Cell. 2016 Jul 28;166(3):609-623. doi: 10.1016/j.cell.2016.06.043. Epub 2016 Jul 21.

9.

Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection.

Yassine HM, Boyington JC, McTamney PM, Wei CJ, Kanekiyo M, Kong WP, Gallagher JR, Wang L, Zhang Y, Joyce MG, Lingwood D, Moin SM, Andersen H, Okuno Y, Rao SS, Harris AK, Kwong PD, Mascola JR, Nabel GJ, Graham BS.

Nat Med. 2015 Sep;21(9):1065-70. doi: 10.1038/nm.3927. Epub 2015 Aug 24.

PMID:
26301691
10.

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo.

Rudicell RS, Kwon YD, Ko SY, Pegu A, Louder MK, Georgiev IS, Wu X, Zhu J, Boyington JC, Chen X, Shi W, Yang ZY, Doria-Rose NA, McKee K, O'Dell S, Schmidt SD, Chuang GY, Druz A, Soto C, Yang Y, Zhang B, Zhou T, Todd JP, Lloyd KE, Eudailey J, Roberts KE, Donald BR, Bailer RT, Ledgerwood J; NISC Comparative Sequencing Program, Mullikin JC, Shapiro L, Koup RA, Graham BS, Nason MC, Connors M, Haynes BF, Rao SS, Roederer M, Kwong PD, Mascola JR, Nabel GJ.

J Virol. 2014 Nov;88(21):12669-82. doi: 10.1128/JVI.02213-14. Epub 2014 Aug 20.

11.

Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor.

Pegu A, Yang ZY, Boyington JC, Wu L, Ko SY, Schmidt SD, McKee K, Kong WP, Shi W, Chen X, Todd JP, Letvin NL, Huang J, Nason MC, Hoxie JA, Kwong PD, Connors M, Rao SS, Mascola JR, Nabel GJ.

Sci Transl Med. 2014 Jul 2;6(243):243ra88. doi: 10.1126/scitranslmed.3008992.

12.

Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.

McLellan JS, Chen M, Joyce MG, Sastry M, Stewart-Jones GB, Yang Y, Zhang B, Chen L, Srivatsan S, Zheng A, Zhou T, Graepel KW, Kumar A, Moin S, Boyington JC, Chuang GY, Soto C, Baxa U, Bakker AQ, Spits H, Beaumont T, Zheng Z, Xia N, Ko SY, Todd JP, Rao S, Graham BS, Kwong PD.

Science. 2013 Nov 1;342(6158):592-8. doi: 10.1126/science.1243283. Erratum in: Science. 2013 Nov 22;342(6161):931.

13.

Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies.

Kanekiyo M, Wei CJ, Yassine HM, McTamney PM, Boyington JC, Whittle JR, Rao SS, Kong WP, Wang L, Nabel GJ.

Nature. 2013 Jul 4;499(7456):102-6. doi: 10.1038/nature12202. Epub 2013 May 22.

PMID:
23698367
14.

Outer domain of HIV-1 gp120: antigenic optimization, structural malleability, and crystal structure with antibody VRC-PG04.

Joyce MG, Kanekiyo M, Xu L, Biertümpfel C, Boyington JC, Moquin S, Shi W, Wu X, Yang Y, Yang ZY, Zhang B, Zheng A, Zhou T, Zhu J, Mascola JR, Kwong PD, Nabel GJ.

J Virol. 2013 Feb;87(4):2294-306. doi: 10.1128/JVI.02717-12. Epub 2012 Dec 12.

15.

Structural and genetic basis for development of broadly neutralizing influenza antibodies.

Lingwood D, McTamney PM, Yassine HM, Whittle JR, Guo X, Boyington JC, Wei CJ, Nabel GJ.

Nature. 2012 Sep 27;489(7417):566-70. doi: 10.1038/nature11371. Epub 2012 Aug 29.

PMID:
22932267
16.

Elicitation of broadly neutralizing influenza antibodies in animals with previous influenza exposure.

Wei CJ, Yassine HM, McTamney PM, Gall JG, Whittle JR, Boyington JC, Nabel GJ.

Sci Transl Med. 2012 Aug 15;4(147):147ra114. doi: 10.1126/scitranslmed.3004273.

17.

Computational prediction of N-linked glycosylation incorporating structural properties and patterns.

Chuang GY, Boyington JC, Joyce MG, Zhu J, Nabel GJ, Kwong PD, Georgiev I.

Bioinformatics. 2012 Sep 1;28(17):2249-55. doi: 10.1093/bioinformatics/bts426. Epub 2012 Jul 10.

18.

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.

McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, Zhou T, Zhu J, Boyington JC, Chuang GY, Diwanji D, Georgiev I, Kwon YD, Lee D, Louder MK, Moquin S, Schmidt SD, Yang ZY, Bonsignori M, Crump JA, Kapiga SH, Sam NE, Haynes BF, Burton DR, Koff WC, Walker LM, Phogat S, Wyatt R, Orwenyo J, Wang LX, Arthos J, Bewley CA, Mascola JR, Nabel GJ, Schief WR, Ward AB, Wilson IA, Kwong PD.

Nature. 2011 Nov 23;480(7377):336-43. doi: 10.1038/nature10696.

19.

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials.

Ledgerwood JE, Wei CJ, Hu Z, Gordon IJ, Enama ME, Hendel CS, McTamney PM, Pearce MB, Yassine HM, Boyington JC, Bailer R, Tumpey TM, Koup RA, Mascola JR, Nabel GJ, Graham BS; VRC 306 Study Team.

Lancet Infect Dis. 2011 Dec;11(12):916-24. doi: 10.1016/S1473-3099(11)70240-7. Epub 2011 Oct 3.

PMID:
21975270
20.

The 1.5 Å crystal structure of human receptor for advanced glycation endproducts (RAGE) ectodomains reveals unique features determining ligand binding.

Park H, Adsit FG, Boyington JC.

J Biol Chem. 2010 Dec 24;285(52):40762-70. doi: 10.1074/jbc.M110.169276. Epub 2010 Oct 13. Erratum in: J Biol Chem. 2011 May 27;286(21):19178. Adsit, Floyd G [added].

21.

Induction of broadly neutralizing H1N1 influenza antibodies by vaccination.

Wei CJ, Boyington JC, McTamney PM, Kong WP, Pearce MB, Xu L, Andersen H, Rao S, Tumpey TM, Yang ZY, Nabel GJ.

Science. 2010 Aug 27;329(5995):1060-4. doi: 10.1126/science.1192517. Epub 2010 Jul 15.

22.

Cross-neutralization of 1918 and 2009 influenza viruses: role of glycans in viral evolution and vaccine design.

Wei CJ, Boyington JC, Dai K, Houser KV, Pearce MB, Kong WP, Yang ZY, Tumpey TM, Nabel GJ.

Sci Transl Med. 2010 Mar 24;2(24):24ra21. doi: 10.1126/scitranslmed.3000799.

23.

Biochemical and structural characterization of cathepsin L-processed Ebola virus glycoprotein: implications for viral entry and immunogenicity.

Hood CL, Abraham J, Boyington JC, Leung K, Kwong PD, Nabel GJ.

J Virol. 2010 Mar;84(6):2972-82. doi: 10.1128/JVI.02151-09. Epub 2010 Jan 6.

24.

Overview of protein folds in the immune system.

Sun PD, Boyington JC.

Curr Protoc Immunol. 2001 Nov;Appendix 1:Appendix 1N. doi: 10.1002/0471142735.ima01ns44.

PMID:
18432648
25.

Overview of protein structural and functional folds.

Sun PD, Foster CE, Boyington JC.

Curr Protoc Protein Sci. 2004 May;Chapter 17:Unit 17.1. doi: 10.1002/0471140864.ps1701s35. Review.

PMID:
18429251
26.

The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1.

Park H, Adsit FG, Boyington JC.

J Biol Chem. 2005 Apr 8;280(14):13593-9. Epub 2005 Feb 5.

27.

A structural perspective on MHC class I recognition by killer cell immunoglobulin-like receptors.

Boyington JC, Sun PD.

Mol Immunol. 2002 May;38(14):1007-21. Review.

PMID:
11955593
28.

Structure of killer cell immunoglobulin-like receptors and their recognition of the class I MHC molecules.

Boyington JC, Brooks AG, Sun PD.

Immunol Rev. 2001 Jun;181:66-78. Review.

PMID:
11513153
29.

Natural killer cell recognition of HLA class I molecules.

Brooks AG, Boyington JC, Sun PD.

Rev Immunogenet. 2000;2(3):433-48. Review.

PMID:
11256749
30.

Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.

Boyington JC, Motyka SA, Schuck P, Brooks AG, Sun PD.

Nature. 2000 Jun 1;405(6786):537-43.

PMID:
10850706
31.

Reconstitution of bacterial expressed human CD94: the importance of the stem region for dimer formation.

Boyington JC, Raiz AN, Brooks AG, Patamawenu A, Sun PD.

Protein Expr Purif. 2000 Mar;18(2):235-41.

PMID:
10686155
32.

Stoichiometric arginine binding in the oxygenase domain of inducible nitric oxide synthase requires a single molecule of tetrahydrobiopterin per dimer.

Rafferty SP, Boyington JC, Kulansky R, Sun PD, Malech HL.

Biochem Biophys Res Commun. 1999 Apr 13;257(2):344-7.

PMID:
10198214
33.

Structure of CD94 reveals a novel C-type lectin fold: implications for the NK cell-associated CD94/NKG2 receptors.

Boyington JC, Riaz AN, Patamawenu A, Coligan JE, Brooks AG, Sun PD.

Immunity. 1999 Jan;10(1):75-82.

34.

Structure and mechanism of lipoxygenases.

Prigge ST, Boyington JC, Faig M, Doctor KS, Gaffney BJ, Amzel LM.

Biochimie. 1997 Nov;79(11):629-36. Review.

PMID:
9479444
35.

Crystal structure of formate dehydrogenase H: catalysis involving Mo, molybdopterin, selenocysteine, and an Fe4S4 cluster.

Boyington JC, Gladyshev VN, Khangulov SV, Stadtman TC, Sun PD.

Science. 1997 Feb 28;275(5304):1305-8.

36.

The three-dimensional structure of soybean lipoxygenase-1: an arachidonic acid 15-lipoxygenase.

Boyington JC, Gaffney BJ, Amzel LM.

Adv Exp Med Biol. 1997;400A:133-8. No abstract available.

PMID:
9547548
37.

Characterization of crystalline formate dehydrogenase H from Escherichia coli. Stabilization, EPR spectroscopy, and preliminary crystallographic analysis.

Gladyshev VN, Boyington JC, Khangulov SV, Grahame DA, Stadtman TC, Sun PD.

J Biol Chem. 1996 Apr 5;271(14):8095-100.

38.

Structure conservation in lipoxygenases: structural analysis of soybean lipoxygenase-1 and modeling of human lipoxygenases.

Prigge ST, Boyington JC, Gaffney BJ, Amzel LM.

Proteins. 1996 Mar;24(3):275-91.

PMID:
8778775
39.

Lipoxygenase structure and mechanism.

Gaffney BJ, Boyington JC, Amzel LM, Doctor KS, Prigge ST, Yuan SM.

Adv Prostaglandin Thromboxane Leukot Res. 1995;23:11-6. Review. No abstract available.

PMID:
7732813
40.

The x-ray structure and biophysical studies of a 15-lipoxygenase.

Boyington JC, Gaffney BJ, Amzel LM, Doctor KS, Mavrophilipos DV, Mavrophilipos ZV, Colom A, Yuan SM.

Ann N Y Acad Sci. 1994 Nov 15;744:310-3. No abstract available.

PMID:
7825855
41.

Structure of soybean lipoxygenase-I.

Boyington JC, Gaffney BJ, Amzel LM.

Biochem Soc Trans. 1993 Aug;21 ( Pt 3)(3):744-8. Review. No abstract available.

PMID:
8224502
42.

The three-dimensional structure of an arachidonic acid 15-lipoxygenase.

Boyington JC, Gaffney BJ, Amzel LM.

Science. 1993 Jun 4;260(5113):1482-6.

PMID:
8502991
43.
44.

The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family.

Joris B, Ghuysen JM, Dive G, Renard A, Dideberg O, Charlier P, Frère JM, Kelly JA, Boyington JC, Moews PC, et al.

Biochem J. 1988 Mar 1;250(2):313-24.

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