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Inflammasome is activated in the liver of cholestatic patients and aggravates hepatic injury in bile duct ligated mouse.

Cai SY, Ge M, Mennone A, Hoque R, Ouyang X, Boyer JL.

Cell Mol Gastroenterol Hepatol. 2019 Dec 27. pii: S2352-345X(19)30184-5. doi: 10.1016/j.jcmgh.2019.12.008. [Epub ahead of print]


OSTα deficiency: A disorder with cholestasis, liver fibrosis and congenital diarrhea.

Gao E, Cheema H, Waheed N, Mushtaq I, Erden N, Nelson-Williams C, Jain D, Soroka CJ, Boyer JL, Khalil Y, Clayton PT, Mistry PK, Lifton RP, Vilarinho S.

Hepatology. 2019 Dec 21. doi: 10.1002/hep.31087. [Epub ahead of print]


Safety and immunogenicity of VGX-3100 formulations in a healthy young adult population.

Hollenberg RK, Krieger DR, Samuels R, Kraynyak K, Sylvester A, Morrow M, Boyer J, Dallas M, Bhuyan PK.

Hum Vaccin Immunother. 2019 Dec 20:1-9. doi: 10.1080/21645515.2019.1695459. [Epub ahead of print]


Inhibition of Osteoclastogenesis by the RNA-Binding Protein QKI5: a Novel Approach to Protect from Bone Resorption.

Rauwel B, Degboé Y, Diallo K, Sayegh S, Baron M, Boyer JF, Constantin A, Cantagrel A, Davignon JL.

J Bone Miner Res. 2019 Dec 13. doi: 10.1002/jbmr.3943. [Epub ahead of print]


[Pharmacogenetics for patient care in France: A discipline that evolves!]

Barin-Le Guellec C, Picard N, Alarcan H, Barreau M, Becquemont L, Quaranta S, Boyer JC, Loriot MA; réseau national de pharmacogénétique (RNPGx).

Therapie. 2019 Oct 30. pii: S0040-5957(19)30154-4. doi: 10.1016/j.therap.2019.09.006. [Epub ahead of print] French.


Integrative proteomic and phosphoproteomic profiling of prostate cell lines.

Katsogiannou M, Boyer JB, Valdeolivas A, Remy E, Calzone L, Audebert S, Rocchi P, Camoin L, Baudot A.

PLoS One. 2019 Nov 1;14(11):e0224148. doi: 10.1371/journal.pone.0224148. eCollection 2019.


Scaffold-Based Analytics: Enabling Hit-to-Lead Decisions by Visualizing Chemical Series Linked across Large Datasets.

Bandyopadhyay D, Kreatsoulas C, Brady PG, Boyer J, He Z, Scavello G Jr, Peryea T, Jadhav A, Nguyen DT, Guha R.

J Chem Inf Model. 2019 Nov 25;59(11):4880-4892. doi: 10.1021/acs.jcim.9b00243. Epub 2019 Oct 29.


Bile acid metabolism and T cell responses in cholangiopathy: Not one-way traffic.

Shetty S, Boyer JL.

J Hepatol. 2019 Oct;71(4):657-659. doi: 10.1016/j.jhep.2019.07.012. Epub 2019 Aug 22. No abstract available.


Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart

Khalil H, Kanisicak O, Vagnozzi RJ, Johansen AK, Maliken BD, Prasad V, Boyer JG, Brody MJ, Schips T, Kilian KK, Correll RN, Kawasaki K, Nagata K, Molkentin JD.

JCI Insight. 2019 Aug 8;4(15):e128722. doi: 10.1172/jci.insight.128722.


Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial.

Modjarrad K, Roberts CC, Mills KT, Castellano AR, Paolino K, Muthumani K, Reuschel EL, Robb ML, Racine T, Oh MD, Lamarre C, Zaidi FI, Boyer J, Kudchodkar SB, Jeong M, Darden JM, Park YK, Scott PT, Remigio C, Parikh AP, Wise MC, Patel A, Duperret EK, Kim KY, Choi H, White S, Bagarazzi M, May JM, Kane D, Lee H, Kobinger G, Michael NL, Weiner DB, Thomas SJ, Maslow JN.

Lancet Infect Dis. 2019 Sep;19(9):1013-1022. doi: 10.1016/S1473-3099(19)30266-X. Epub 2019 Jul 24.


2018 Annual Report of the Accreditation Council for Pharmacy Education

Vlasses PH, Wadelin JW, Boyer JG, Travlos DV, Rouse MJ, Avery C.

Am J Pharm Educ. 2019 Jun;83(5):7598. doi: 10.5688/ajpe7598. No abstract available.


Tensile force exerted by suture during renorrhaphy using current techniques.

Zanghi J, Boyer J, Martinez C, Patel A, Petit C, Siegert J, Nguyen T.

J Robot Surg. 2019 Jul 12. doi: 10.1007/s11701-019-00999-y. [Epub ahead of print]


Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223.

Calvente CJ, Tameda M, Johnson CD, Del Pilar H, Lin YC, Adronikou N, De Mollerat Du Jeu X, Llorente C, Boyer J, Feldstein AE.

J Clin Invest. 2019 Jul 11;130:4091-4109. doi: 10.1172/JCI122258.


[Interest and difficulties in setting up pharmaceutical reconciliations for patients with dressings for complex wounds].

Painchart L, Drancourt P, Aubert J, Inghels Y, Boyer J.

Ann Pharm Fr. 2019 Nov;77(6):516-531. doi: 10.1016/j.pharma.2019.06.003. Epub 2019 Jun 26. French.


[Dihydropyrimidine dehydrogenase deficiency screening for management of patients receiving a fluoropyrimidine: Results of two national practice surveys addressed to clinicians and biologists].

Loriot MA, Masskouri F, Carni P, Le Malicot K, Seitz JF, Michel P, Legoux JL, Bouché O, André T, Faroux R, Delaloge S, Malka D, Guigay J, Thariat J, Thomas F, Barin-Le-Guellec C, Ciccolini J, Boyer JC, Étienne-Grimaldi MC.

Bull Cancer. 2019 Sep;106(9):759-775. doi: 10.1016/j.bulcan.2019.04.013. Epub 2019 Jun 25. French.


Effects of Vedolizumab in Patients With Primary Sclerosing Cholangitis and Inflammatory Bowel Diseases.

Lynch KD, Chapman RW, Keshav S, Montano-Loza AJ, Mason AL, Kremer AE, Vetter M, de Krijger M, Ponsioen CY, Trivedi P, Hirschfield G, Schramm C, Liu CH, Bowlus CL, Estes DJ, Pratt D, Hedin C, Bergquist A, de Vries AC, van der Woude CJ, Yu L, Assis DN, Boyer J, Ytting H, Hallibasic E, Trauner M, Marschall HU, Daretti LM, Marzioni M, Yimam KK, Perin N, Floreani A, Beretta-Piccoli BT, Rogers JK; International Primary Sclerosing Cholangitis Study Group (IPSCSG), Levy C.

Clin Gastroenterol Hepatol. 2020 Jan;18(1):179-187.e6. doi: 10.1016/j.cgh.2019.05.013. Epub 2019 May 14.


Olecranon bursitis secondary to Mycobacterium europaeum infection in a patient receiving immunosuppressive drugs for rheumatoid arthritis.

Dutertre M, Delobel P, Marchou B, Boyer JF, Mougari F, Martin-Blondel G.

Med Mal Infect. 2019 Aug;49(5):358-359. doi: 10.1016/j.medmal.2019.03.002. Epub 2019 May 14. No abstract available.


[Acute carpal tunnel syndrome caused by a thrombosis of a persistent median artery: 2 case reports].

Avenel M, Miranda S, Benhamou Y, Michelin P, Boyer JC, Lévesque H, Armengol G.

Rev Med Interne. 2019 Jul;40(7):453-456. doi: 10.1016/j.revmed.2019.04.002. Epub 2019 Apr 28. French.


Review: Endogenously Produced Volatiles for In Vitro Toxicity Testing Using Cell Lines.

Winters BR, Pleil JD, Boyer JC, Nylander-French LA, Wallace MAG, Madden MC.

Appl In Vitro Toxicol. 2018 Jun 1;4(2):129-138. doi: 10.1089/aivt.2017.0038. Review.


Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies.

Soroka CJ, Assis DN, Boyer JL.

Methods Mol Biol. 2019;1981:363-372. doi: 10.1007/978-1-4939-9420-5_24.


Analyzing and comparing complex environmental time series using a cumulative sums approach.

Regier P, Briceño H, Boyer JN.

MethodsX. 2019 Apr 9;6:779-787. doi: 10.1016/j.mex.2019.03.014. eCollection 2019.


Publisher Correction: Low genetic variation is associated with low mutation rate in the giant duckweed.

Xu S, Stapley J, Gablenz S, Boyer J, Appenroth KJ, Sree KS, Gershenzon J, Widmer A, Huber M.

Nat Commun. 2019 Apr 16;10(1):1857. doi: 10.1038/s41467-019-09796-5.


ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity.

Boyer JG, Prasad V, Song T, Lee D, Fu X, Grimes KM, Sargent MA, Sadayappan S, Molkentin JD.

JCI Insight. 2019 Apr 9;5. pii: 127356. doi: 10.1172/jci.insight.127356.


Autosomal recessive Treacher Collins syndrome due to POLR1C mutations: Report of a new family and review of the literature.

Ghesh L, Vincent M, Delemazure AS, Boyer J, Corre P, Perez F, Geneviève D, Laplanche JL, Collet C, Isidor B.

Am J Med Genet A. 2019 Jul;179(7):1390-1394. doi: 10.1002/ajmg.a.61147. Epub 2019 Apr 8.


Targeting Cytokine Signaling and Lymphocyte Traffic via Small Molecules in Inflammatory Bowel Disease: JAK Inhibitors and S1PR Agonists.

Pérez-Jeldres T, Tyler CJ, Boyer JD, Karuppuchamy T, Yarur A, Giles DA, Yeasmin S, Lundborg L, Sandborn WJ, Patel DR, Rivera-Nieves J.

Front Pharmacol. 2019 Mar 13;10:212. doi: 10.3389/fphar.2019.00212. eCollection 2019. Review.


Intradermal SynCon® Ebola GP DNA Vaccine Is Temperature Stable and Safely Demonstrates Cellular and Humoral Immunogenicity Advantages in Healthy Volunteers.

Tebas P, Kraynyak KA, Patel A, Maslow JN, Morrow MP, Sylvester AJ, Knoblock D, Gillespie E, Amante D, Racine T, McMullan T, Jeong M, Roberts CC, Park YK, Boyer J, Broderick KE, Kobinger GP, Bagarazzi M, Weiner DB, Sardesai NY, White SM.

J Infect Dis. 2019 Jul 2;220(3):400-410. doi: 10.1093/infdis/jiz132.


Low genetic variation is associated with low mutation rate in the giant duckweed.

Xu S, Stapley J, Gablenz S, Boyer J, Appenroth KJ, Sree KS, Gershenzon J, Widmer A, Huber M.

Nat Commun. 2019 Mar 20;10(1):1243. doi: 10.1038/s41467-019-09235-5. Erratum in: Nat Commun. 2019 Apr 16;10(1):1857.


Harold J. Fallon, M.D. (1931-2018).

Boyer JL.

Hepatology. 2019 May;69(5):2308-2309. doi: 10.1002/hep.30585. Epub 2019 Mar 27. No abstract available.


Factors Affecting Tamoxifen Metabolism in Patients With Breast Cancer: Preliminary Results of the French PHACS Study.

Puszkiel A, Arellano C, Vachoux C, Evrard A, Le Morvan V, Boyer JC, Robert J, Delmas C, Dalenc F, Debled M, Venat-Bouvet L, Jacot W, Suc E, Sillet-Bach I, Filleron T, Roché H, Chatelut E, White-Koning M, Thomas F.

Clin Pharmacol Ther. 2019 Sep;106(3):585-595. doi: 10.1002/cpt.1404. Epub 2019 Apr 10.


Polarization of Rheumatoid Macrophages by TNF Targeting Through an IL-10/STAT3 Mechanism.

Degboé Y, Rauwel B, Baron M, Boyer JF, Ruyssen-Witrand A, Constantin A, Davignon JL.

Front Immunol. 2019 Jan 18;10:3. doi: 10.3389/fimmu.2019.00003. eCollection 2019.


Bile-Derived Organoids From Patients With Primary Sclerosing Cholangitis Recapitulate Their Inflammatory Immune Profile.

Soroka CJ, Assis DN, Alrabadi LS, Roberts S, Cusack L, Jaffe AB, Boyer JL.

Hepatology. 2019 Sep;70(3):871-882. doi: 10.1002/hep.30470. Epub 2019 Mar 13.


Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays.

Zeng X, Kirkpatrick R, Hofmann G, Grillot D, Linhart V, Viviani F, Marino J Jr, Boyer J, Graham TL, Lu Q, Wu Z, Benowitz A, Cousins R.

PLoS One. 2018 Dec 12;13(12):e0207140. doi: 10.1371/journal.pone.0207140. eCollection 2018.


How can we best monitor 5-FU administration to maximize benefit to risk ratio?

Goirand F, Lemaitre F, Launay M, Tron C, Chatelut E, Boyer JC, Bardou M, Schmitt A.

Expert Opin Drug Metab Toxicol. 2018 Dec;14(12):1303-1313. doi: 10.1080/17425255.2018.1550484. Epub 2018 Nov 23. Review.


The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle.

Kwong JQ, Huo J, Bround MJ, Boyer JG, Schwanekamp JA, Ghazal N, Maxwell JT, Jang YC, Khuchua Z, Shi K, Bers DM, Davis J, Molkentin JD.

JCI Insight. 2018 Nov 15;3(22). pii: 121689. doi: 10.1172/jci.insight.121689.


Can I Have Your Recipe? Using a Fidelity of Implementation (FOI) Framework to Identify the Key Ingredients of Formative Assessment for Learning.

Offerdahl EG, McConnell M, Boyer J.

CBE Life Sci Educ. 2018 Dec;17(4):es16. doi: 10.1187/cbe.18-02-0029.


H19 Is Expressed in Hybrid Hepatocyte Nuclear Factor 4α+ Periportal Hepatocytes but Not Cytokeratin 19+ Cholangiocytes in Cholestatic Livers.

Jiang Y, Huang Y, Cai S, Song Y, Boyer JL, Zhang K, Gao L, Zhao J, Huang W, Liang G, Liangpunsakul S, Wang L.

Hepatol Commun. 2018 Sep 24;2(11):1356-1368. doi: 10.1002/hep4.1252. eCollection 2018 Nov.


Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy.

Vitale LA, Thomas LJ, He LZ, O'Neill T, Widger J, Crocker A, Sundarapandiyan K, Storey JR, Forsberg EM, Weidlick J, Baronas AR, Gergel LE, Boyer JM, Sisson C, Goldstein J, Marsh HC Jr, Keler T.

Cancer Immunol Immunother. 2019 Feb;68(2):233-245. doi: 10.1007/s00262-018-2267-0. Epub 2018 Oct 31.


Modulation of T-cell responses by anti-tumor necrosis factor treatments in rheumatoid arthritis: a review.

Davignon JL, Rauwel B, Degboé Y, Constantin A, Boyer JF, Kruglov A, Cantagrel A.

Arthritis Res Ther. 2018 Oct 12;20(1):229. doi: 10.1186/s13075-018-1725-6. Review.


Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines.

Patel A, Reuschel EL, Kraynyak KA, Racine T, Park DH, Scott VL, Audet J, Amante D, Wise MC, Keaton AA, Wong G, Villarreal DO, Walters J, Muthumani K, Shedlock DJ, de La Vega MA, Plyler R, Boyer J, Broderick KE, Yan J, Khan AS, Jones S, Bello A, Soule G, Tran KN, He S, Tierney K, Qiu X, Kobinger GP, Sardesai NY, Weiner DB.

J Infect Dis. 2019 Jan 29;219(4):544-555. doi: 10.1093/infdis/jiy537.


Bile Infarcts: New Insights Into the Pathogenesis of Obstructive Cholestasis.

Cai SY, Boyer JL.

Hepatology. 2019 Feb;69(2):473-475. doi: 10.1002/hep.30291. Epub 2019 Jan 16. No abstract available.


Immunotherapy Targeting HPV16/18 Generates Potent Immune Responses in HPV-Associated Head and Neck Cancer.

Aggarwal C, Cohen RB, Morrow MP, Kraynyak KA, Sylvester AJ, Knoblock DM, Bauml JM, Weinstein GS, Lin A, Boyer J, Sakata L, Tan S, Anton A, Dickerson K, Mangrolia D, Vang R, Dallas M, Oyola S, Duff S, Esser M, Kumar R, Weiner D, Csiki I, Bagarazzi ML.

Clin Cancer Res. 2019 Jan 1;25(1):110-124. doi: 10.1158/1078-0432.CCR-18-1763. Epub 2018 Sep 21.


An in Vivo Imaging Assay Detects Spatial Variability in Glucose Release from Plant Roots.

Voothuluru P, Braun DM, Boyer JS.

Plant Physiol. 2018 Nov;178(3):1002-1010. doi: 10.1104/pp.18.00614. Epub 2018 Sep 20.


Cell Trafficking Interference in Inflammatory Bowel Disease: Therapeutic Interventions Based on Basic Pathogenesis Concepts.

Pérez-Jeldres T, Tyler CJ, Boyer JD, Karuppuchamy T, Bamias G, Dulai PS, Boland BS, Sandborn WJ, Patel DR, Rivera-Nieves J.

Inflamm Bowel Dis. 2019 Jan 10;25(2):270-282. doi: 10.1093/ibd/izy269. Review.


Liver Complications Following Treatment of Hematologic Malignancy With Anti-CD22-Calicheamicin (Inotuzumab Ozogamicin).

McDonald GB, Freston JW, Boyer JL, DeLeve LD.

Hepatology. 2019 Feb;69(2):831-844. doi: 10.1002/hep.30222. Epub 2019 Jan 18.


[5-fluorouracil therapeutic drug monitoring: Update and recommendations of the STP-PT group of the SFPT and the GPCO-Unicancer].

Lemaitre F, Goirand F, Launay M, Chatelut E, Boyer JC, Evrard A, Paludetto MN, Guilhaumou R, Ciccolini J, Schmitt A.

Bull Cancer. 2018 Sep;105(9):790-803. doi: 10.1016/j.bulcan.2018.06.008. Epub 2018 Aug 10. Review. French.


Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases.

Lindor KD, Bowlus CL, Boyer J, Levy C, Mayo M.

Hepatology. 2019 Jan;69(1):394-419. doi: 10.1002/hep.30145. Epub 2018 Nov 6. No abstract available.


Solute Carrier Organic Anion Transporter Family Member 3A1 Is a Bile Acid Efflux Transporter in Cholestasis.

Pan Q, Zhang X, Zhang L, Cheng Y, Zhao N, Li F, Zhou X, Chen S, Li J, Xu S, Huang D, Chen Y, Li L, Wang H, Chen W, Cai SY, Boyer JL, Chai J.

Gastroenterology. 2018 Nov;155(5):1578-1592.e16. doi: 10.1053/j.gastro.2018.07.031. Epub 2018 Jul 29.


Histologic features of autoimmune hepatitis: a critical appraisal.

Gurung A, Assis DN, McCarty TR, Mitchell KA, Boyer JL, Jain D.

Hum Pathol. 2018 Dec;82:51-60. doi: 10.1016/j.humpath.2018.07.014. Epub 2018 Jul 21.


O-GlcNAcylation site mapping by (azide-alkyne) click chemistry and mass spectrometry following intensive fractionation of skeletal muscle cells proteins.

Deracinois B, Camoin L, Lambert M, Boyer JB, Dupont E, Bastide B, Cieniewski-Bernard C.

J Proteomics. 2018 Aug 30;186:83-97. doi: 10.1016/j.jprot.2018.07.005. Epub 2018 Jul 26.


Normative and conceptual ELSI research: what it is, and why it's important.

Parker LS, Sankar PL, Boyer J, Jean McEwen JD, Kaufman D.

Genet Med. 2019 Feb;21(2):505-509. doi: 10.1038/s41436-018-0065-x. Epub 2018 Jul 4.


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