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Items: 22

1.

The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure.

Boyer DR, Li B, Sun C, Fan W, Zhou K, Hughes MP, Sawaya MR, Jiang L, Eisenberg DS.

Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3592-3602. doi: 10.1073/pnas.1917914117. Epub 2020 Feb 3.

PMID:
32015135
2.

Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs.

Boyer DR, Li B, Sun C, Fan W, Sawaya MR, Jiang L, Eisenberg DS.

Nat Struct Mol Biol. 2019 Nov;26(11):1044-1052. doi: 10.1038/s41594-019-0322-y. Epub 2019 Nov 6.

PMID:
31695184
3.

Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples.

Seidler PM, Boyer DR, Murray KA, Yang TP, Bentzel M, Sawaya MR, Rosenberg G, Cascio D, Williams CK, Newell KL, Ghetti B, DeTure MA, Dickson DW, Vinters HV, Eisenberg DS.

J Biol Chem. 2019 Nov 1;294(44):16451-16464. doi: 10.1074/jbc.RA119.009688. Epub 2019 Sep 19.

PMID:
31537646
4.

Author Correction: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.

Guenther EL, Cao Q, Trinh H, Lu J, Sawaya MR, Cascio D, Boyer DR, Rodriguez JA, Hughes MP, Eisenberg DS.

Nat Struct Mol Biol. 2019 Oct;26(10):988. doi: 10.1038/s41594-019-0316-9.

PMID:
31530939
5.

Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface.

Warmack RA, Boyer DR, Zee CT, Richards LS, Sawaya MR, Cascio D, Gonen T, Eisenberg DS, Clarke SG.

Nat Commun. 2019 Jul 26;10(1):3357. doi: 10.1038/s41467-019-11183-z.

6.

Cryo-EM structures of four polymorphic TDP-43 amyloid cores.

Cao Q, Boyer DR, Sawaya MR, Ge P, Eisenberg DS.

Nat Struct Mol Biol. 2019 Jul;26(7):619-627. doi: 10.1038/s41594-019-0248-4. Epub 2019 Jun 24.

PMID:
31235914
7.

Nanoscale mosaicity revealed in peptide microcrystals by scanning electron nanodiffraction.

Gallagher-Jones M, Ophus C, Bustillo KC, Boyer DR, Panova O, Glynn C, Zee CT, Ciston J, Mancia KC, Minor AM, Rodriguez JA.

Commun Biol. 2019 Jan 18;2:26. doi: 10.1038/s42003-018-0263-8. eCollection 2019.

8.

Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel.

Li B, Ge P, Murray KA, Sheth P, Zhang M, Nair G, Sawaya MR, Shin WS, Boyer DR, Ye S, Eisenberg DS, Zhou ZH, Jiang L.

Nat Commun. 2018 Sep 6;9(1):3609. doi: 10.1038/s41467-018-05971-2.

9.

Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.

Guenther EL, Cao Q, Trinh H, Lu J, Sawaya MR, Cascio D, Boyer DR, Rodriguez JA, Hughes MP, Eisenberg DS.

Nat Struct Mol Biol. 2018 Jun;25(6):463-471. doi: 10.1038/s41594-018-0064-2. Epub 2018 May 21. Erratum in: Nat Struct Mol Biol. 2019 Oct;26(10):988.

10.

Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.

Guenther EL, Ge P, Trinh H, Sawaya MR, Cascio D, Boyer DR, Gonen T, Zhou ZH, Eisenberg DS.

Nat Struct Mol Biol. 2018 Apr;25(4):311-319. doi: 10.1038/s41594-018-0045-5. Epub 2018 Mar 12.

11.

Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks.

Hughes MP, Sawaya MR, Boyer DR, Goldschmidt L, Rodriguez JA, Cascio D, Chong L, Gonen T, Eisenberg DS.

Science. 2018 Feb 9;359(6376):698-701. doi: 10.1126/science.aan6398.

12.

Structure-based inhibitors of tau aggregation.

Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS.

Nat Chem. 2018 Feb;10(2):170-176. doi: 10.1038/nchem.2889. Epub 2017 Nov 20.

13.

Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp.

Gallagher-Jones M, Glynn C, Boyer DR, Martynowycz MW, Hernandez E, Miao J, Zee CT, Novikova IV, Goldschmidt L, McFarlane HT, Helguera GF, Evans JE, Sawaya MR, Cascio D, Eisenberg DS, Gonen T, Rodriguez JA.

Nat Struct Mol Biol. 2018 Feb;25(2):131-134. doi: 10.1038/s41594-017-0018-0. Epub 2018 Jan 15.

14.

Ultrafast Time-Resolved Studies on Fluorescein for Recognition Strands Architecture in Amyloid Fibrils.

Hanczyc P, Mikhailovsky A, Boyer DR, Sawaya MR, Heeger A, Eisenberg D.

J Phys Chem B. 2018 Jan 11;122(1):8-18. doi: 10.1021/acs.jpcb.7b07923. Epub 2018 Jan 3.

PMID:
29237120
15.

Isofunctional enzymes PAD1 and UbiX catalyze formation of a novel cofactor required by ferulic acid decarboxylase and 4-hydroxy-3-polyprenylbenzoic acid decarboxylase.

Lin F, Ferguson KL, Boyer DR, Lin XN, Marsh EN.

ACS Chem Biol. 2015 Apr 17;10(4):1137-44. doi: 10.1021/cb5008103. Epub 2015 Feb 3.

PMID:
25647642
16.

Implementation of an evidence-based bladder scanner protocol.

Boyer DR, Steltzer N, Larrabee JH.

J Nurs Care Qual. 2009 Jan-Mar;24(1):10-6. doi: 10.1097/NCQ.0b013e31818f52bd. No abstract available.

PMID:
19092473
17.

Music and medicine.

Boyer DR.

Pharos Alpha Omega Alpha Honor Med Soc. 1992 Summer;55(3):41. No abstract available.

PMID:
1409864
18.

Studies of the role of membrane lipid order in the effects of delta 9-tetrahydrocannabinol on adenylate cyclase activation in heart.

Hillard CJ, Pounds JJ, Boyer DR, Bloom AS.

J Pharmacol Exp Ther. 1990 Mar;252(3):1075-82.

PMID:
2156989
19.

Post-embedding direct immunogold detection of a protein antigen in insect tissue.

Myers CR, Bergtrom G, Crook SM, Boyer DR, Collins ML.

J Histochem Cytochem. 1986 Feb;34(2):221-6.

PMID:
3511140
20.

Interaction of temperature and hypoxia on respiratory and cardiac responses in the lizard, Sauromalus obesus.

Boyer DR.

Comp Biochem Physiol. 1967 Feb;20(2):437-47. No abstract available.

PMID:
6035555
21.

Hypoxia: effects on heart rate and respiration in the snapping turtle.

BOYER DR.

Science. 1963 May 17;140(3568):813-4.

PMID:
14014707
22.

Effects of temperature and body size upon heart rate and oxygen consumption in turtles.

HUTTON KE, BOYER DR, WILLIAMS JC, CAMPBELL PM.

J Cell Comp Physiol. 1960 Feb;55:87-93. No abstract available.

PMID:
14405655

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