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Items: 25


Disease-Modifying Effects of a Novel Cathepsin K Inhibitor in Osteoarthritis: A Randomized, Placebo-Controlled Study.

Conaghan PG, Bowes MA, Kingsbury SR, Brett A, Guillard G, Rizoska B, Sjögren N, Graham P, Jansson Å, Wadell C, Bethell R, Öhd J.

Ann Intern Med. 2019 Dec 31. doi: 10.7326/M19-0675. [Epub ahead of print]


Very early MRI responses to therapy as a predictor of later radiographic progression in early rheumatoid arthritis.

Conaghan PG, Østergaard M, Troum O, Bowes MA, Guillard G, Wilkinson B, Xie Z, Andrews J, Stein A, Chapman D, Koenig A.

Arthritis Res Ther. 2019 Oct 21;21(1):214. doi: 10.1186/s13075-019-2000-1.


Precision, Reliability, and Responsiveness of a Novel Automated Quantification Tool for Cartilage Thickness: Data from the Osteoarthritis Initiative.

Bowes MA, Guillard GA, Vincent GR, Brett AD, Wolstenholme CBH, Conaghan PG.

J Rheumatol. 2020 Feb;47(2):282-289. doi: 10.3899/jrheum.180541. Epub 2019 Apr 15.


Marked and rapid change of bone shape in acutely ACL injured knees - an exploratory analysis of the Kanon trial.

Bowes MA, Lohmander LS, Wolstenholme CBH, Vincent GR, Conaghan PG, Frobell RB.

Osteoarthritis Cartilage. 2019 Apr;27(4):638-645. doi: 10.1016/j.joca.2018.12.021. Epub 2019 Jan 14.


The relationship between two different measures of osteoarthritis bone pathology, bone marrow lesions and 3D bone shape: data from the Osteoarthritis Initiative.

Dube B, Bowes MA, Hensor EMA, Barr A, Kingsbury SR, Conaghan PG.

Osteoarthritis Cartilage. 2018 Oct;26(10):1333-1337. doi: 10.1016/j.joca.2018.06.011. Epub 2018 Jul 12.


The influence of psychosocial factors in veteran adjustment to civilian life.

Bowes MA, Ferreira N, Henderson M.

Clin Psychol Psychother. 2018 Mar 25. doi: 10.1002/cpp.2182. [Epub ahead of print]


Bisphosphonates intake and its association with changes of periarticular bone area and three-dimensional shape: data from the Osteoarthritis Initiative (OAI).

Haj-Mirzaian A, Guermazi A, Roemer FW, Bowes MA, Conaghan PG, Demehri S.

Osteoarthritis Cartilage. 2018 Apr;26(4):564-568. doi: 10.1016/j.joca.2018.01.005. Epub 2018 Jan 9.


Where does meniscal damage progress most rapidly? An analysis using three-dimensional shape models on data from the Osteoarthritis Initiative.

Dube B, Bowes MA, Kingsbury SR, Hensor EMA, Muzumdar S, Conaghan PG.

Osteoarthritis Cartilage. 2018 Jan;26(1):62-71. doi: 10.1016/j.joca.2017.10.012. Epub 2017 Oct 17.


Patellofemoral morphology is not related to pain using three-dimensional quantitative analysis in an older population: data from the Osteoarthritis Initiative.

Drew BT, Bowes MA, Redmond AC, Dube B, Kingsbury SR, Conaghan PG.

Rheumatology (Oxford). 2017 Dec 1;56(12):2135-2144. doi: 10.1093/rheumatology/kex329.


Repeatability and response to therapy of dynamic contrast-enhanced magnetic resonance imaging biomarkers in rheumatoid arthritis in a large multicentre trial setting.

Waterton JC, Ho M, Nordenmark LH, Jenkins M, DiCarlo J, Guillard G, Roberts C, Buonaccorsi G, Parker GJM, Bowes MA, Peterfy C, Kellner H, Taylor PC.

Eur Radiol. 2017 Sep;27(9):3662-3668. doi: 10.1007/s00330-017-4736-9. Epub 2017 Jan 23.


Bone Area Provides a Responsive Outcome Measure for Bone Changes in Short-term Knee Osteoarthritis Studies.

Bowes MA, Maciewicz RA, Waterton JC, Hunter DJ, Conaghan PG.

J Rheumatol. 2016 Dec;43(12):2179-2182. Epub 2016 Oct 1.


The relationship between three-dimensional knee MRI bone shape and total knee replacement-a case control study: data from the Osteoarthritis Initiative.

Barr AJ, Dube B, Hensor EM, Kingsbury SR, Peat G, Bowes MA, Sharples LD, Conaghan PG.

Rheumatology (Oxford). 2016 Sep;55(9):1585-93. doi: 10.1093/rheumatology/kew191. Epub 2016 May 15.


Comparing the effects of tofacitinib, methotrexate and the combination, on bone marrow oedema, synovitis and bone erosion in methotrexate-naive, early active rheumatoid arthritis: results of an exploratory randomised MRI study incorporating semiquantitative and quantitative techniques.

Conaghan PG, Østergaard M, Bowes MA, Wu C, Fuerst T, van der Heijde D, Irazoque-Palazuelos F, Soto-Raices O, Hrycaj P, Xie Z, Zhang R, Wyman BT, Bradley JD, Soma K, Wilkinson B.

Ann Rheum Dis. 2016 Jun;75(6):1024-33. doi: 10.1136/annrheumdis-2015-208267. Epub 2016 Jan 25.


Osteoarthritic bone marrow lesions almost exclusively colocate with denuded cartilage: a 3D study using data from the Osteoarthritis Initiative.

Bowes MA, McLure SW, Wolstenholme CB, Vincent GR, Williams S, Grainger A, Conaghan PG.

Ann Rheum Dis. 2016 Oct;75(10):1852-7. doi: 10.1136/annrheumdis-2015-208407. Epub 2015 Dec 15.


A systematic review of the relationship between subchondral bone features, pain and structural pathology in peripheral joint osteoarthritis.

Barr AJ, Campbell TM, Hopkinson D, Kingsbury SR, Bowes MA, Conaghan PG.

Arthritis Res Ther. 2015 Aug 25;17:228. doi: 10.1186/s13075-015-0735-x. Review.


The relationship between clinical characteristics, radiographic osteoarthritis and 3D bone area: data from the osteoarthritis initiative.

Barr AJ, Dube B, Hensor EM, Kingsbury SR, Peat G, Bowes MA, Conaghan PG.

Osteoarthritis Cartilage. 2014 Oct;22(10):1703-9. doi: 10.1016/j.joca.2014.06.026.


A novel method for bone area measurement provides new insights into osteoarthritis and its progression.

Bowes MA, Vincent GR, Wolstenholme CB, Conaghan PG.

Ann Rheum Dis. 2015 Mar;74(3):519-25. doi: 10.1136/annrheumdis-2013-204052. Epub 2013 Dec 4.


Magnetic resonance imaging-based three-dimensional bone shape of the knee predicts onset of knee osteoarthritis: data from the osteoarthritis initiative.

Neogi T, Bowes MA, Niu J, De Souza KM, Vincent GR, Goggins J, Zhang Y, Felson DT.

Arthritis Rheum. 2013 Aug;65(8):2048-58. doi: 10.1002/art.37987.


Effect of bisphosphonate use in patients with symptomatic and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative.

Laslett LL, Kingsbury SR, Hensor EM, Bowes MA, Conaghan PG.

Ann Rheum Dis. 2014 May;73(5):824-30. doi: 10.1136/annrheumdis-2012-202989. Epub 2013 Apr 12.


Can cartilage loss be detected in knee osteoarthritis (OA) patients with 3-6 months' observation using advanced image analysis of 3T MRI?

Hunter DJ, Bowes MA, Eaton CB, Holmes AP, Mann H, Kwoh CK, Maciewicz RA, Samuels J, Waterton JC.

Osteoarthritis Cartilage. 2010 May;18(5):677-83. doi: 10.1016/j.joca.2010.02.010. Epub 2010 Feb 26.


Analgesic profile of the nicotinic acetylcholine receptor agonists, (+)-epibatidine and ABT-594 in models of persistent inflammatory and neuropathic pain.

Kesingland AC, Gentry CT, Panesar MS, Bowes MA, Vernier JM, Cube R, Walker K, Urban L.

Pain. 2000 May;86(1-2):113-8.


Endopeptidase-24.11: a cell-surface enzyme for metabolizing regulatory peptides.

Kenny AJ, Bowes MA, Gee NS, Matsas R.

Biochem Soc Trans. 1985 Apr;13(2):293-5. No abstract available.


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