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Items: 17

1.

The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth.

Bowers LW, Lineberger CG, Ford NA, Rossi EL, Punjala A, Camp KK, Kimler BK, Fabian CJ, Hursting SD.

Breast Cancer Res Treat. 2019 Feb;173(3):545-557. doi: 10.1007/s10549-018-5021-6. Epub 2018 Oct 26.

2.

Leptin Signaling Mediates Obesity-Associated CSC Enrichment and EMT in Preclinical TNBC Models.

Bowers LW, Rossi EL, McDonell SB, Doerstling SS, Khatib SA, Lineberger CG, Albright JE, Tang X, deGraffenried LA, Hursting SD.

Mol Cancer Res. 2018 May;16(5):869-879. doi: 10.1158/1541-7786.MCR-17-0508. Epub 2018 Feb 16.

3.

Resveratrol inhibits obesity-associated adipose tissue dysfunction and tumor growth in a mouse model of postmenopausal claudin-low breast cancer.

Rossi EL, Khatib SA, Doerstling SS, Bowers LW, Pruski M, Ford NA, Glickman RD, Niu M, Yang P, Cui Z, DiGiovanni J, Hursting SD.

Mol Carcinog. 2018 Mar;57(3):393-407. doi: 10.1002/mc.22763. Epub 2017 Dec 1.

4.

Translating Mechanism-Based Strategies to Break the Obesity-Cancer Link: A Narrative Review.

Smith LA, O'Flanagan CH, Bowers LW, Allott EH, Hursting SD.

J Acad Nutr Diet. 2018 Apr;118(4):652-667. doi: 10.1016/j.jand.2017.08.112. Review.

5.

Signals from the Adipose Microenvironment and the Obesity-Cancer Link-A Systematic Review.

Himbert C, Delphan M, Scherer D, Bowers LW, Hursting S, Ulrich CM.

Cancer Prev Res (Phila). 2017 Sep;10(9):494-506. doi: 10.1158/1940-6207.CAPR-16-0322. Review.

6.

Energy Balance Modulation Impacts Epigenetic Reprogramming, ERα and ERβ Expression, and Mammary Tumor Development in MMTV-neu Transgenic Mice.

Rossi EL, Dunlap SM, Bowers LW, Khatib SA, Doerstling SS, Smith LA, Ford NA, Holley D, Brown PH, Estecio MR, Kusewitt DF, deGraffenried LA, Bultman SJ, Hursting SD.

Cancer Res. 2017 May 1;77(9):2500-2511. doi: 10.1158/0008-5472.CAN-16-2795. Epub 2017 Apr 3.

7.

Reducing the burden of obesity-associated cancers with anti-inflammatory long-chain omega-3 polyunsaturated fatty acids.

Khatib SA, Rossi EL, Bowers LW, Hursting SD.

Prostaglandins Other Lipid Mediat. 2016 Sep;125:100-7. doi: 10.1016/j.prostaglandins.2016.07.011. Epub 2016 Jul 19. Review.

8.

Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice.

Rossi EL, de Angel RE, Bowers LW, Khatib SA, Smith LA, Van Buren E, Bhardwaj P, Giri D, Estecio MR, Troester MA, Hair BY, Kirk EL, Gong T, Shen J, Dannenberg AJ, Hursting SD.

Cancer Prev Res (Phila). 2016 May;9(5):339-48. doi: 10.1158/1940-6207.CAPR-15-0348. Epub 2016 Feb 11.

9.

Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway.

Bowers LW, Wiese M, Brenner AJ, Rossi EL, Tekmal RR, Hursting SD, deGraffenried LA.

PLoS One. 2015 Dec 28;10(12):e0145452. doi: 10.1371/journal.pone.0145452. eCollection 2015.

10.

Targeting the COX-2 Pathway to Improve Therapeutic Response in the Obese Breast Cancer Patient Population.

Bowers LW, deGraffenried LA.

Curr Pharmacol Rep. 2015 Oct 1;1(5):336-345. Epub 2015 Apr 22.

11.

A weighty problem: metabolic perturbations and the obesity-cancer link.

O'Flanagan CH, Bowers LW, Hursting SD.

Horm Mol Biol Clin Investig. 2015 Aug;23(2):47-57. doi: 10.1515/hmbci-2015-0022. Review.

12.

Omega-3-Acid Ethyl Esters Block the Protumorigenic Effects of Obesity in Mouse Models of Postmenopausal Basal-like and Claudin-Low Breast Cancer.

Ford NA, Rossi EL, Barnett K, Yang P, Bowers LW, Hidaka BH, Kimler BF, Carlson SE, Shureiqi I, deGraffenried LA, Fabian CJ, Hursting SD.

Cancer Prev Res (Phila). 2015 Sep;8(9):796-806. doi: 10.1158/1940-6207.CAPR-15-0018. Epub 2015 Jun 22.

13.

The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link.

Bowers LW, Rossi EL, O'Flanagan CH, deGraffenried LA, Hursting SD.

Front Endocrinol (Lausanne). 2015 May 15;6:77. doi: 10.3389/fendo.2015.00077. eCollection 2015. Review.

14.

Obesity-associated systemic interleukin-6 promotes pre-adipocyte aromatase expression via increased breast cancer cell prostaglandin E2 production.

Bowers LW, Brenner AJ, Hursting SD, Tekmal RR, deGraffenried LA.

Breast Cancer Res Treat. 2015 Jan;149(1):49-57. doi: 10.1007/s10549-014-3223-0. Epub 2014 Dec 5.

15.

Obesity promotes aerobic glycolysis in prostate cancer cells.

Cavazos DA, deGraffenried MJ, Apte SA, Bowers LW, Whelan KA, deGraffenried LA.

Nutr Cancer. 2014;66(7):1179-86. doi: 10.1080/01635581.2014.951738. Epub 2014 Sep 29.

16.

NSAID use reduces breast cancer recurrence in overweight and obese women: role of prostaglandin-aromatase interactions.

Bowers LW, Maximo IX, Brenner AJ, Beeram M, Hursting SD, Price RS, Tekmal RR, Jolly CA, deGraffenried LA.

Cancer Res. 2014 Aug 15;74(16):4446-57. doi: 10.1158/0008-5472.CAN-13-3603.

17.

Obesity enhances nongenomic estrogen receptor crosstalk with the PI3K/Akt and MAPK pathways to promote in vitro measures of breast cancer progression.

Bowers LW, Cavazos DA, Maximo IX, Brenner AJ, Hursting SD, deGraffenried LA.

Breast Cancer Res. 2013;15(4):R59.

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