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Items: 1 to 50 of 76

1.

T follicular helper-like cells contribute to skin fibrosis.

Taylor DK, Mittereder N, Kuta E, Delaney T, Burwell T, Dacosta K, Zhao W, Cheng LI, Brown C, Boutrin A, Guo X, White WI, Zhu J, Dong H, Bowen MA, Lin J, Gao C, Yu L, Ramaswamy M, Gaudreau MC, Woods R, Herbst R, Carlesso G.

Sci Transl Med. 2018 Mar 7;10(431). pii: eaaf5307. doi: 10.1126/scitranslmed.aaf5307.

PMID:
29514998
2.

A novel bicistronic gene design couples stable cell line selection with a fucose switch in a designer CHO host to produce native and afucosylated glycoform antibodies.

Roy G, Martin T, Barnes A, Wang J, Jimenez RB, Rice M, Li L, Feng H, Zhang S, Chaerkady R, Wu H, Marelli M, Hatton D, Zhu J, Bowen MA.

MAbs. 2018 Apr;10(3):416-430. doi: 10.1080/19420862.2018.1433975. Epub 2018 Feb 22.

3.

Uncovering heterogeneous interactions in online commercial networks.

Zhang F, Zeng A, Ma B, Fan Y, Di Z.

Sci Rep. 2017 Dec 8;7(1):17209. doi: 10.1038/s41598-017-17410-1.

4.

History and Practice of Thyroid Fine-Needle Aspiration in China, Based on Retrospective Study of the Practice in Shandong University Qilu Hospital.

Liu Z, Liu D, Ma B, Zhang X, Su P, Chen L, Zeng Q.

J Pathol Transl Med. 2017 Nov;51(6):528-532. doi: 10.4132/jptm.2017.09.12. Epub 2017 Oct 19. Review.

5.

Sequential screening by ClonePix FL and intracellular staining facilitate isolation of high producer cell lines for monoclonal antibody manufacturing.

Roy G, Miro-Quesada G, Zhuang L, Martin T, Zhu J, Wu H, Marelli M, Bowen MA.

J Immunol Methods. 2017 Dec;451:100-110. doi: 10.1016/j.jim.2017.08.012. Epub 2017 Sep 8.

PMID:
28890364
6.

Lessons from the Hamster: Cricetulus griseus Tissue and CHO Cell Line Proteome Comparison.

Heffner KM, Hizal DB, Yerganian GS, Kumar A, Can Ö, O'Meally R, Cole R, Chaerkady R, Wu H, Bowen MA, Betenbaugh MJ.

J Proteome Res. 2017 Oct 6;16(10):3672-3687. doi: 10.1021/acs.jproteome.7b00382. Epub 2017 Sep 14.

PMID:
28876938
7.

Development of a fluorescent reporter system for monitoring ER stress in Chinese hamster ovary cells and its application for therapeutic protein production.

Roy G, Zhang S, Li L, Higham E, Wu H, Marelli M, Bowen MA.

PLoS One. 2017 Aug 23;12(8):e0183694. doi: 10.1371/journal.pone.0183694. eCollection 2017.

8.

Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.

Douthwaite J, Moisan J, Privezentzev C, Soskic B, Sabbah S, Cohen S, Collinson A, England E, Huntington C, Kemp B, Zhuang L, Hudak S, Rees DG, Goldberg D, Barton C, Chang L, Vainshtein I, Liang M, Iciek L, Ambery P, Peakman M, Vaughan TJ, Tree TIM, Sansom DM, Bowen MA, Minter RR, Jermutus L.

J Immunol. 2017 Sep 1;199(5):1943. doi: 10.4049/jimmunol.1790013. No abstract available.

PMID:
28827388
9.

Statistical Models for the Analysis of Isobaric Tags Multiplexed Quantitative Proteomics.

D'Angelo G, Chaerkady R, Yu W, Hizal DB, Hess S, Zhao W, Lekstrom K, Guo X, White WI, Roskos L, Bowen MA, Yang H.

J Proteome Res. 2017 Sep 1;16(9):3124-3136. doi: 10.1021/acs.jproteome.6b01050. Epub 2017 Aug 18.

PMID:
28745510
10.

CD6 as a potential target for treating multiple sclerosis.

Li Y, Singer NG, Whitbred J, Bowen MA, Fox DA, Lin F.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2687-2692. doi: 10.1073/pnas.1615253114. Epub 2017 Feb 16.

11.

Guiding bispecific monovalent antibody formation through proteolysis of IgG1 single-chain.

Dimasi N, Fleming R, Sachsenmeier KF, Bezabeh B, Hay C, Wu J, Sult E, Rajan S, Zhuang L, Cariuk P, Buchanan A, Bowen MA, Wu H, Gao C.

MAbs. 2017 Apr;9(3):438-454. doi: 10.1080/19420862.2016.1277301. Epub 2017 Jan 5.

12.

High-Throughput Lipidomic and Transcriptomic Analysis To Compare SP2/0, CHO, and HEK-293 Mammalian Cell Lines.

Zhang Y, Baycin-Hizal D, Kumar A, Priola J, Bahri M, Heffner KM, Wang M, Han X, Bowen MA, Betenbaugh MJ.

Anal Chem. 2017 Feb 7;89(3):1477-1485. doi: 10.1021/acs.analchem.6b02984. Epub 2017 Jan 9.

PMID:
27991764
13.

A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.

Douthwaite J, Moisan J, Privezentzev C, Soskic B, Sabbah S, Cohen S, Collinson A, England E, Huntington C, Kemp B, Zhuang L, Hudak S, Rees DG, Goldberg D, Barton C, Chang L, Vainshtein I, Liang M, Iciek L, Ambery P, Peakman M, Vaughan TJ, Tree TI, Sansom DM, Bowen MA, Minter RR, Jermutus L.

J Immunol. 2017 Jan 1;198(1):528-537. Epub 2016 Nov 23. Erratum in: J Immunol. 2017 Sep 1;199(5):1943.

14.

The TGF-β inhibitory activity of antibody 37E1B5 depends on its H-CDR2 glycan.

Tsui P, Higazi DR, Wu Y, Dunmore R, Solier E, Kasali T, Bond NJ, Huntington C, Carruthers A, Hood J, Borrok MJ, Barnes A, Rickert K, Phipps S, Shirinian L, Zhu J, Bowen MA, Dall'Acqua W, Murray LA.

MAbs. 2017 Jan;9(1):104-113. doi: 10.1080/19420862.2016.1255390. Epub 2016 Nov 11.

15.

Interconversion of Peptide Mass Spectral Libraries Derivatized with iTRAQ or TMT Labels.

Zhang Z, Yang X, Mirokhin YA, Tchekhovskoi DV, Ji W, Markey SP, Roth J, Neta P, Hizal DB, Bowen MA, Stein SE.

J Proteome Res. 2016 Sep 2;15(9):3180-7. doi: 10.1021/acs.jproteome.6b00406. Epub 2016 Aug 8.

PMID:
27386737
16.

Combining phage display with de novo protein sequencing for reverse engineering of monoclonal antibodies.

Rickert KW, Grinberg L, Woods RM, Wilson S, Bowen MA, Baca M.

MAbs. 2016;8(3):501-12. doi: 10.1080/19420862.2016.1145865.

17.

Variation analysis of EXO1 gene in Chinese patients with premature ovarian failure.

Su S, Han T, Ma B, Li W, Qin Y, Zhao S, Chen ZJ.

Reprod Biomed Online. 2016 Mar;32(3):329-33. doi: 10.1016/j.rbmo.2015.12.003. Epub 2015 Dec 29.

PMID:
26774993
18.

A sensitive LC-MS/MS method to quantify methylergonovine in human plasma and its application to a pharmacokinetic study.

Gao Y, Sun Q, Liu D, Ma B, Zhao H, Fang Z, Wang H, Lou H.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Feb 1;1011:62-8. doi: 10.1016/j.jchromb.2015.12.046. Epub 2015 Dec 28.

PMID:
26760224
19.

Cellular traffic cops: the interplay between lipids and proteins regulates vesicular formation, trafficking, and signaling in mammalian cells.

Kumar A, Baycin-Hizal D, Zhang Y, Bowen MA, Betenbaugh MJ.

Curr Opin Biotechnol. 2015 Dec;36:215-21. doi: 10.1016/j.copbio.2015.09.006. Epub 2015 Nov 2. Review.

PMID:
26540512
20.

Structural insights into the interaction of human IgG1 with FcγRI: no direct role of glycans in binding.

Oganesyan V, Mazor Y, Yang C, Cook KE, Woods RM, Ferguson A, Bowen MA, Martin T, Zhu J, Wu H, Dall'Acqua WF.

Acta Crystallogr D Biol Crystallogr. 2015 Nov;71(Pt 11):2354-61. doi: 10.1107/S1399004715018015. Epub 2015 Oct 31.

21.

Interventional Magnetic Resonance Imaging Clinic: The Emory University Experience.

Nour SG, Powell TE, Eberhardt J, Bowen MA, Pennington G, Meltzer CC.

Magn Reson Imaging Clin N Am. 2015 Nov;23(4):681-8. doi: 10.1016/j.mric.2015.07.001. Review.

PMID:
26499284
22.

Elucidation of the CHO Super-Ome (CHO-SO) by Proteoinformatics.

Kumar A, Baycin-Hizal D, Wolozny D, Pedersen LE, Lewis NE, Heffner K, Chaerkady R, Cole RN, Shiloach J, Zhang H, Bowen MA, Betenbaugh MJ.

J Proteome Res. 2015 Nov 6;14(11):4687-703. doi: 10.1021/acs.jproteome.5b00588. Epub 2015 Oct 13.

23.

The Impact of Nonphysician Providers on Diagnostic and Interventional Radiology Practices: Operational and Educational Implications.

Hawkins CM, Bowen MA, Gilliland CA, Walls DG, Duszak R Jr.

J Am Coll Radiol. 2015 Sep;12(9):898-904. doi: 10.1016/j.jacr.2015.03.034.

PMID:
26355201
24.

Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry.

VanBrunt MP, Shanebeck K, Caldwell Z, Johnson J, Thompson P, Martin T, Dong H, Li G, Xu H, D'Hooge F, Masterson L, Bariola P, Tiberghien A, Ezeadi E, Williams DG, Hartley JA, Howard PW, Grabstein KH, Bowen MA, Marelli M.

Bioconjug Chem. 2015 Nov 18;26(11):2249-60. doi: 10.1021/acs.bioconjchem.5b00359. Epub 2015 Sep 11.

PMID:
26332743
25.

A Neutralizing Antibody Assay Based on a Reporter of Antibody-Dependent Cell-Mediated Cytotoxicity.

Wu Y, Li JJ, Kim HJ, Liu X, Liu W, Akhgar A, Bowen MA, Spitz S, Jiang XR, Roskos LK, White WI.

AAPS J. 2015 Nov;17(6):1417-26. doi: 10.1208/s12248-015-9798-5. Epub 2015 Jul 24.

26.

The impact of nonphysician providers on diagnostic and interventional radiology practices: regulatory, billing, and compliance perspectives.

Hawkins CM, Bowen MA, Gilliland CA, Walls DG, Duszak R Jr.

J Am Coll Radiol. 2015 Aug;12(8):776-81. doi: 10.1016/j.jacr.2015.03.036. Epub 2015 May 23. Review.

PMID:
26006744
27.

Development of an antibody that neutralizes soluble IgE and eliminates IgE expressing B cells.

Nyborg AC, Zacco A, Ettinger R, Jack Borrok M, Zhu J, Martin T, Woods R, Kiefer C, Bowen MA, Suzanne Cohen E, Herbst R, Wu H, Coats S.

Cell Mol Immunol. 2016 May;13(3):391-400. doi: 10.1038/cmi.2015.19. Epub 2015 Mar 23.

28.

Risks associated with premature ovarian failure in Han Chinese women.

Wang H, Chen H, Qin Y, Shi Z, Zhao X, Xu J, Ma B, Chen ZJ.

Reprod Biomed Online. 2015 Apr;30(4):401-7. doi: 10.1016/j.rbmo.2014.12.013. Epub 2015 Jan 13.

PMID:
25682306
29.

Coupling enrichment methods with proteomics for understanding and treating disease.

Kumar A, Baycin-Hizal D, Shiloach J, Bowen MA, Betenbaugh MJ.

Proteomics Clin Appl. 2015 Feb;9(1-2):33-47. doi: 10.1002/prca.201400097. Epub 2015 Jan 19. Review.

PMID:
25523641
30.

Expanding roles of nurse practitioners and physician assistants as providers of nonvascular invasive radiology procedures.

Duszak R Jr, Walls DG, Wang JM, Hemingway J, Hughes DR, Small WC, Bowen MA.

J Am Coll Radiol. 2015 Mar;12(3):284-9. doi: 10.1016/j.jacr.2014.08.021. Epub 2014 Oct 16.

PMID:
25444061
31.

Subjective and objective findings in patients with true dehiscence versus thin bone over the superior semicircular canal.

Mehta R, Klumpp ML, Spear SA, Bowen MA, Arriaga MA, Ying YL.

Otol Neurotol. 2015 Feb;36(2):289-94. doi: 10.1097/MAO.0000000000000654.

PMID:
25406871
32.

Exploiting the proteomics revolution in biotechnology: from disease and antibody targets to optimizing bioprocess development.

Heffner KM, Hizal DB, Kumar A, Shiloach J, Zhu J, Bowen MA, Betenbaugh MJ.

Curr Opin Biotechnol. 2014 Dec;30:80-6. doi: 10.1016/j.copbio.2014.06.006. Epub 2014 Jul 3. Review.

PMID:
24997444
33.
34.

Engineering a therapeutic IgG molecule to address cysteinylation, aggregation and enhance thermal stability and expression.

Buchanan A, Clementel V, Woods R, Harn N, Bowen MA, Mo W, Popovic B, Bishop SM, Dall'Acqua W, Minter R, Jermutus L, Bedian V.

MAbs. 2013 Mar-Apr;5(2):255-62. doi: 10.4161/mabs.23392. Epub 2013 Feb 14.

35.

Highly stable and efficient Ag/AgCl@TiO2 photocatalyst: preparation, characterization, and application in the treatment of aqueous hazardous pollutants.

Guo JF, Ma B, Yin A, Fan K, Dai WL.

J Hazard Mater. 2012 Apr 15;211-212:77-82. doi: 10.1016/j.jhazmat.2011.11.082. Epub 2011 Dec 1.

PMID:
22178280
36.

A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo.

Ward E, Mittereder N, Kuta E, Sims GP, Bowen MA, Dall'Acqua W, Tedder T, Kiener P, Coyle AJ, Wu H, Jallal B, Herbst R.

Br J Haematol. 2011 Nov;155(4):426-37. doi: 10.1111/j.1365-2141.2011.08857.x. Epub 2011 Sep 9.

PMID:
21902688
37.

Whole-molecule antibody engineering: generation of a high-affinity anti-IL-6 antibody with extended pharmacokinetics.

Finch DK, Sleeman MA, Moisan J, Ferraro F, Botterell S, Campbell J, Cochrane D, Cruwys S, England E, Lane S, Rendall E, Sinha M, Walker C, Rees G, Bowen MA, Schneider A, Liang M, Faggioni R, Fung M, Mallinder PR, Wilkinson T, Kolbeck R, Vaughan T, Lowe DC.

J Mol Biol. 2011 Aug 26;411(4):791-807. doi: 10.1016/j.jmb.2011.06.031. Epub 2011 Jun 23.

PMID:
21723291
38.

Diagnostic and interventional sialendoscopy: a preliminary experience.

Bowen MA, Tauzin M, Kluka EA, Nuss DW, DiLeo M, McWhorter AJ, Schaitkin B, Walvekar RR.

Laryngoscope. 2011 Feb;121(2):299-303. doi: 10.1002/lary.21390. Epub 2011 Jan 14.

PMID:
21271577
39.

B-cell depletion in vitro and in vivo with an afucosylated anti-CD19 antibody.

Herbst R, Wang Y, Gallagher S, Mittereder N, Kuta E, Damschroder M, Woods R, Rowe DC, Cheng L, Cook K, Evans K, Sims GP, Pfarr DS, Bowen MA, Dall'Acqua W, Shlomchik M, Tedder TF, Kiener P, Jallal B, Wu H, Coyle AJ.

J Pharmacol Exp Ther. 2010 Oct;335(1):213-22. doi: 10.1124/jpet.110.168062. Epub 2010 Jul 6. Erratum in: J Pharmacol Exp Ther. 2011 Jan;336(1):294. Dall'Aqua, William [corrected to Dall'Acqua, William].

40.

Nonphysician providers in radiology: the Emory University experience.

Bowen MA, Torres WE, Small WC.

Radiology. 2007 Oct;245(1):3-6. No abstract available.

PMID:
17885173
41.

CD166 expression, characterization, and localization in salivary epithelium: implications for function during sialoadenitis.

Abidi SM, Saifullah MK, Zafiropulos MD, Kaput C, Bowen MA, Cotton C, Singer NG.

J Clin Immunol. 2006 Jan;26(1):12-21.

PMID:
16418799
42.

High circulating levels of soluble scavenger receptors (sCD5 and sCD6) in patients with primary Sjögren's syndrome.

Ramos-Casals M, Font J, García-Carrasco M, Calvo J, Places L, Padilla O, Cervera R, Bowen MA, Lozano F, Ingelmo M.

Rheumatology (Oxford). 2001 Sep;40(9):1056-9.

PMID:
11561119
43.

CD5 signal transduction: positive or negative modulation of antigen receptor signaling.

Lozano F, Simarro M, Calvo J, Vilà JM, Padilla O, Bowen MA, Campbell KS.

Crit Rev Immunol. 2000;20(4):347-58. Review.

PMID:
11100806
44.

Cell surface receptors and their ligands: in vitro analysis of CD6-CD166 interactions.

Bowen MA, Aruffo AA, Bajorath J.

Proteins. 2000 Aug 15;40(3):420-8. Review.

PMID:
10861932
45.

CD5 is A potential selecting ligand for B-cell surface immunoglobulin: a possible role in maintenance and selective expansion of normal and malignant B cells.

Pospisil R, Silverman GJ, Marti GE, Aruffo A, Bowen MA, Mage RG.

Leuk Lymphoma. 2000 Jan;36(3-4):353-65.

PMID:
10674908
46.

Relevance of individual CD5 extracellular domains on antibody recognition, glycosylation and co-mitogenic signalling.

Calvo J, Padilla O, Places L, Vigorito E, Vilà JM, Vilella R, Milà J, Vives J, Bowen MA, Lozano F.

Tissue Antigens. 1999 Jul;54(1):16-26.

PMID:
10458319
47.

Interaction of recombinant and natural soluble CD5 forms with an alternative cell surface ligand.

Calvo J, Places L, Padilla O, Vilà JM, Vives J, Bowen MA, Lozano F.

Eur J Immunol. 1999 Jul;29(7):2119-29.

48.

Adhesion molecules, their receptors, and their regulation: analysis of CD6-activated leukocyte cell adhesion molecule (ALCAM/CD166) interactions.

Bowen MA, Aruffo A.

Transplant Proc. 1999 Feb-Mar;31(1-2):795-6. Review. No abstract available.

PMID:
10083342
49.

CD5 negatively regulates the T-cell antigen receptor signal transduction pathway: involvement of SH2-containing phosphotyrosine phosphatase SHP-1.

Perez-Villar JJ, Whitney GS, Bowen MA, Hewgill DH, Aruffo AA, Kanner SB.

Mol Cell Biol. 1999 Apr;19(4):2903-12.

50.

Analysis of the tyrosine phosphorylation and calcium fluxing of human CD6 isoforms with different cytoplasmatic domains.

Kobarg J, Whitney GS, Palmer D, Aruffo A, Bowen MA.

Eur J Immunol. 1997 Nov;27(11):2971-80.

PMID:
9394826

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