Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 687


Structural Insight into G Protein-Coupled Receptor Signaling Efficacy and Bias between Gs and β-Arrestin.

Picard LP, Schonegge AM, Bouvier M.

ACS Pharmacol Transl Sci. 2019 Apr 3;2(3):148-154. doi: 10.1021/acsptsci.9b00012. eCollection 2019 Jun 14.


Beta-arrestins operate an on/off control switch for focal adhesion kinase activity.

Alexander RA, Lot I, Saha K, Abadie G, Lambert M, Decosta E, Kobayashi H, Beautrait A, Borrull A, Asnacios A, Bouvier M, Scott MGH, Marullo S, Enslen H.

Cell Mol Life Sci. 2020 Feb 10. doi: 10.1007/s00018-020-03471-5. [Epub ahead of print]


RNA processing machineries in Archaea: the 5'-3' exoribonuclease aRNase J of the β-CASP family is engaged specifically with the helicase ASH-Ski2 and the 3'-5' exoribonucleolytic RNA exosome machinery.

Phung DK, Etienne C, Batista M, Langendijk-Genevaux P, Moalic Y, Laurent S, Liuu S, Morales V, Jebbar M, Fichant G, Bouvier M, Flament D, Clouet-d'Orval B.

Nucleic Acids Res. 2020 Feb 7. pii: gkaa052. doi: 10.1093/nar/gkaa052. [Epub ahead of print]


Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment.

García RA, Ito BR, Lupisella JA, Carson NA, Hsu MY, Fernando G, Heroux M, Bouvier M, Dierks E, Kick EK, Gordon DA, Chen J, Mintier G, Carrier M, St-Onge S, Shah H, Towne J, Bucardo MS, Ma X, Ryan CS, Wurtz NR, Ostrowski J, Villarreal FJ.

JACC Basic Transl Sci. 2019 Nov 13;4(8):905-920. doi: 10.1016/j.jacbts.2019.07.005. eCollection 2019 Dec.


Is the extent of obstetric anal sphincter injury correlated with the severity of fecal incontinence in the long term?

Luciano L, Bouvier M, Baumstarck K, Vitton V.

Tech Coloproctol. 2020 Jan;24(1):49-55. doi: 10.1007/s10151-019-02128-1. Epub 2019 Dec 9.


Immune evasion by adenoviruses: a window into host-virus adaptation.

Oliveira ERA, Bouvier M.

FEBS Lett. 2019 Dec;593(24):3496-3503. doi: 10.1002/1873-3468.13682. Epub 2019 Dec 5. Review.


Phase I/II multisite trial of optimally dosed clofarabine and low-dose TBI for hematopoietic cell transplantation in acute myeloid leukemia.

Krakow EF, Gyurkocza B, Storer BE, Chauncey TR, McCune JS, Radich JP, Bouvier ME, Estey EH, Storb R, Maloney DG, Sandmaier BM.

Am J Hematol. 2020 Jan;95(1):48-56. doi: 10.1002/ajh.25665. Epub 2019 Nov 8.


ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.

Li L, Batliwala M, Bouvier M.

J Biol Chem. 2019 Dec 6;294(49):18534-18544. doi: 10.1074/jbc.RA119.010102. Epub 2019 Oct 10.


Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response.

Benredjem B, Gallion J, Pelletier D, Dallaire P, Charbonneau J, Cawkill D, Nagi K, Gosink M, Lukasheva V, Jenkinson S, Ren Y, Somps C, Murat B, Van Der Westhuizen E, Le Gouill C, Lichtarge O, Schmidt A, Bouvier M, Pineyro G.

Nat Commun. 2019 Sep 9;10(1):4075. doi: 10.1038/s41467-019-11875-6.


Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics.

Pedersen MF, Wróbel TM, Märcher-Rørsted E, Pedersen DS, Møller TC, Gabriele F, Pedersen H, Matosiuk D, Foster SR, Bouvier M, Bräuner-Osborne H.

Neuropharmacology. 2020 Apr;166:107718. doi: 10.1016/j.neuropharm.2019.107718. Epub 2019 Jul 24.


The Safety of Maternal and Fetal MRI at 3 T.

Chartier AL, Bouvier MJ, McPherson DR, Stepenosky JE, Taysom DA, Marks RM.

AJR Am J Roentgenol. 2019 Nov;213(5):1170-1173. doi: 10.2214/AJR.19.21400. Epub 2019 Jul 16.


Discovery of Potent Protease-Activated Receptor 4 Antagonists with in Vivo Antithrombotic Efficacy.

Miller MM, Banville J, Friends TJ, Gagnon M, Hangeland JJ, Lavallée JF, Martel A, O'Grady H, Rémillard R, Ruediger E, Tremblay F, Posy SL, Allegretto NJ, Guarino VR, Harden DG, Harper TW, Hartl K, Josephs J, Malmstrom S, Watson C, Yang Y, Zhang G, Wong P, Yang J, Bouvier M, Seiffert DA, Wexler RR, Lawrence RM, Priestley ES, Marinier A.

J Med Chem. 2019 Aug 22;62(16):7400-7416. doi: 10.1021/acs.jmedchem.9b00186. Epub 2019 Aug 5.


Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs.

Wang W, Shen M, Fischer C, Basu R, Hazra S, Couvineau P, Paul M, Wang F, Toth S, Mix DS, Poglitsch M, Gerard NP, Bouvier M, Vederas JC, Penninger JM, Kassiri Z, Oudit GY.

Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13006-13015. doi: 10.1073/pnas.1900152116. Epub 2019 Jun 12.


In Vitro Studies of MHC Class I Peptide Loading and Exchange.

Bouvier M.

Methods Mol Biol. 2019;1988:71-81. doi: 10.1007/978-1-4939-9450-2_6.


Trimming of MHC Class I Ligands by ERAP Aminopeptidases.

Weimershaus M, Evnouchidou I, Li L, van Endert P, Bouvier M.

Methods Mol Biol. 2019;1988:31-43. doi: 10.1007/978-1-4939-9450-2_3.


Shipboard Global Health Engagement Missions: Essential Lessons for Military Healthcare Personnel.

King HC, Bouvier M, Todd N, Bryan CJ, Montalto G, Johnson C, Hawkins R, Braun LA, Malone J, Kelley PW.

Mil Med. 2019 Dec 1;184(11-12):e758-e764. doi: 10.1093/milmed/usz113.


Author Correction: Hybridization is a recurrent evolutionary stimulus in wild yeast speciation.

Eberlein C, Hénault M, Fijarczyk A, Charron G, Bouvier M, Kohn LM, Anderson JB, Landry CR.

Nat Commun. 2019 May 13;10(1):2199. doi: 10.1038/s41467-019-09702-z.


Impact of Organic Coating on Soot Angular and Spectral Scattering Properties.

Lefevre G, Yon J, Bouvier M, Liu F, Coppalle A.

Environ Sci Technol. 2019 Jun 4;53(11):6383-6391. doi: 10.1021/acs.est.8b05482. Epub 2019 May 14.


Three-dimensional high-resolution anorectal manometry can predict response to biofeedback therapy in defecation disorders.

Andrianjafy C, Luciano L, Loundou A, Bouvier M, Vitton V.

Int J Colorectal Dis. 2019 Jun;34(6):1131-1140. doi: 10.1007/s00384-019-03297-z. Epub 2019 May 1.


Hybridization of β-Adrenergic Agonists and Antagonists Confers G Protein Bias.

Stanek M, Picard LP, Schmidt MF, Kaindl JM, Hübner H, Bouvier M, Weikert D, Gmeiner P.

J Med Chem. 2019 May 23;62(10):5111-5131. doi: 10.1021/acs.jmedchem.9b00349. Epub 2019 May 13.


Chemogenetics defines receptor-mediated functions of short chain free fatty acids.

Bolognini D, Barki N, Butcher AJ, Hudson BD, Sergeev E, Molloy C, Moss CE, Bradley SJ, Le Gouill C, Bouvier M, Tobin AB, Milligan G.

Nat Chem Biol. 2019 May;15(5):489-498. doi: 10.1038/s41589-019-0270-1. Epub 2019 Apr 15.


Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons.

Ehrlich AT, Semache M, Gross F, Da Fonte DF, Runtz L, Colley C, Mezni A, Le Gouill C, Lukasheva V, Hogue M, Darcq E, Bouvier M, Kieffer BL.

iScience. 2019 Apr 26;14:47-57. doi: 10.1016/j.isci.2019.03.011. Epub 2019 Mar 15.


Bioluminescence resonance energy transfer-based imaging of protein-protein interactions in living cells.

Kobayashi H, Picard LP, Schönegge AM, Bouvier M.

Nat Protoc. 2019 Apr;14(4):1084-1107. doi: 10.1038/s41596-019-0129-7. Epub 2019 Mar 25.


Detachment of the RNA degradosome from the inner membrane of Escherichia coli results in a global slowdown of mRNA degradation, proteolysis of RNase E and increased turnover of ribosome-free transcripts.

Hadjeras L, Poljak L, Bouvier M, Morin-Ogier Q, Canal I, Cocaign-Bousquet M, Girbal L, Carpousis AJ.

Mol Microbiol. 2019 Jun;111(6):1715-1731. doi: 10.1111/mmi.14248. Epub 2019 Apr 6.


Agonist-induced desensitisation of β3 -adrenoceptors: Where, when, and how?

Okeke K, Angers S, Bouvier M, Michel MC.

Br J Pharmacol. 2019 Jul;176(14):2539-2558. doi: 10.1111/bph.14633. Epub 2019 Apr 7. Review.


Hybridization is a recurrent evolutionary stimulus in wild yeast speciation.

Eberlein C, Hénault M, Fijarczyk A, Charron G, Bouvier M, Kohn LM, Anderson JB, Landry CR.

Nat Commun. 2019 Feb 25;10(1):923. doi: 10.1038/s41467-019-08809-7. Erratum in: Nat Commun. 2019 May 13;10(1):2199.


Can wearing high heels influence anal canal pressure and the severity of fecal incontinence?

Vitton V, Luciano L, Ortiz S, Baumstarck K, Bouvier M.

Int Urogynecol J. 2019 Dec;30(12):2049-2054. doi: 10.1007/s00192-019-03902-3. Epub 2019 Feb 22.


Three-dimensional high-resolution anorectal manometry in functional anorectal disorders: results from a large observational cohort study.

Andrianjafy C, Luciano L, Bazin C, Baumstarck K, Bouvier M, Vitton V.

Int J Colorectal Dis. 2019 Apr;34(4):719-729. doi: 10.1007/s00384-019-03235-z. Epub 2019 Jan 31.


Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist.

Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BK.

Nat Chem Biol. 2019 Feb;15(2):205. doi: 10.1038/s41589-018-0182-5.


Large-Scale Measurement of mRNA Degradation in Escherichia coli: To Delay or Not to Delay.

Laguerre S, González I, Nouaille S, Moisan A, Villa-Vialaneix N, Gaspin C, Bouvier M, Carpousis AJ, Cocaign-Bousquet M, Girbal L.

Methods Enzymol. 2018;612:47-66. doi: 10.1016/bs.mie.2018.07.003. Epub 2018 Aug 29.


FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs.

Wright SC, Cañizal MCA, Benkel T, Simon K, Le Gouill C, Matricon P, Namkung Y, Lukasheva V, König GM, Laporte SA, Carlsson J, Kostenis E, Bouvier M, Schulte G, Hoffmann C.

Sci Signal. 2018 Dec 4;11(559). pii: eaar5536. doi: 10.1126/scisignal.aar5536.


Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors.

Namkung Y, LeGouill C, Kumar S, Cao Y, Teixeira LB, Lukasheva V, Giubilaro J, Simões SC, Longpré JM, Devost D, Hébert TE, Piñeyro G, Leduc R, Costa-Neto CM, Bouvier M, Laporte SA.

Sci Signal. 2018 Dec 4;11(559). pii: eaat1631. doi: 10.1126/scisignal.aat1631.


Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion.

Hamoud N, Tran V, Aimi T, Kakegawa W, Lahaie S, Thibault MP, Pelletier A, Wong GW, Kim IS, Kania A, Yuzaki M, Bouvier M, Côté JF.

Nat Commun. 2018 Oct 26;9(1):4470. doi: 10.1038/s41467-018-06897-5.


Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist.

Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BK.

Nat Chem Biol. 2018 Nov;14(11):1059-1066. doi: 10.1038/s41589-018-0145-x. Epub 2018 Oct 16. Erratum in: Nat Chem Biol. 2019 Feb;15(2):205.


Translating biased signaling in the ghrelin receptor system into differential in vivo functions.

Mende F, Hundahl C, Plouffe B, Skov LJ, Sivertsen B, Madsen AN, Lückmann M, Diep TA, Offermanns S, Frimurer TM, Bouvier M, Holst B.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10255-E10264. doi: 10.1073/pnas.1804003115. Epub 2018 Oct 9.


Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes.

Picard LP, Schönegge AM, Lohse MJ, Bouvier M.

Commun Biol. 2018 Aug 7;1:106. doi: 10.1038/s42003-018-0101-z. eCollection 2018.


Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9.

Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, Shenoy SK, Laporte SA, Rockman HA, Lefkowitz RJ.

Sci Signal. 2018 Sep 25;11(549). pii: eaat7650. doi: 10.1126/scisignal.aat7650.


Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling.

Karamitri A, Plouffe B, Bonnefond A, Chen M, Gallion J, Guillaume JL, Hegron A, Boissel M, Canouil M, Langenberg C, Wareham NJ, Le Gouill C, Lukasheva V, Lichtarge O, Froguel P, Bouvier M, Jockers R.

Sci Signal. 2018 Aug 28;11(545). pii: eaan6622. doi: 10.1126/scisignal.aan6622.


Discovery of small molecule inhibitors of adenovirus by disrupting E3-19K/HLA-A2 interactions.

Ren J, Dsouza NR, Deng H, Lee H, Bouvier M, Johnson ME.

Bioorg Med Chem Lett. 2018 Sep 15;28(17):2837-2841. doi: 10.1016/j.bmcl.2018.07.036. Epub 2018 Jul 29.


Computational design of orthogonal membrane receptor-effector switches for rewiring signaling pathways.

Young M, Dahoun T, Sokrat B, Arber C, Chen KM, Bouvier M, Barth P.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7051-7056. doi: 10.1073/pnas.1718489115. Epub 2018 Jun 18.


Milk Fat Globules Hamper Adhesion of Enterohemorrhagic Escherichia coli to Enterocytes: In Vitro and in Vivo Evidence.

Douëllou T, Galia W, Kerangart S, Marchal T, Milhau N, Bastien R, Bouvier M, Buff S, Montel MC, Sergentet-Thevenot D.

Front Microbiol. 2018 May 15;9:947. doi: 10.3389/fmicb.2018.00947. eCollection 2018.


Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors.

Chaturvedi M, Schilling J, Beautrait A, Bouvier M, Benovic JL, Shukla AK.

Trends Biochem Sci. 2018 Jul;43(7):533-546. doi: 10.1016/j.tibs.2018.04.003. Epub 2018 May 4. Review.


Insights into RNA-processing pathways and associated RNA-degrading enzymes in Archaea.

Clouet-d'Orval B, Batista M, Bouvier M, Quentin Y, Fichant G, Marchfelder A, Maier LK.

FEMS Microbiol Rev. 2018 Sep 1;42(5):579-613. doi: 10.1093/femsre/fuy016. Review.


Indeterminate genotypes of hepatitis C virus by the Abbott RealTime HCV Genotype II assay in Morocco. About eight cases resolved by a sequencing method.

Mesbahi Z, Kabbaj H, Malki H, Bouihat N, Qrafli M, Belefquih B, Marcil S, Challine D, Pawlotsky JM, Bouvier M, Seffar M.

J Med Virol. 2018 Aug;90(8):1352-1357. doi: 10.1002/jmv.25191. Epub 2018 Apr 26.


Monitoring ligand-dependent assembly of receptor ternary complexes in live cells by BRETFect.

Cotnoir-White D, El Ezzy M, Boulay PL, Rozendaal M, Bouvier M, Gagnon E, Mader S.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2653-E2662. doi: 10.1073/pnas.1716224115. Epub 2018 Feb 27.


Effects of haloperidol and clozapine on synapse-related gene expression in specific brain regions of male rats.

von Wilmsdorff M, Manthey F, Bouvier ML, Staehlin O, Falkai P, Meisenzahl-Lechner E, Schmitt A, Gebicke-Haerter PJ.

Eur Arch Psychiatry Clin Neurosci. 2018 Sep;268(6):555-563. doi: 10.1007/s00406-018-0872-8. Epub 2018 Feb 5.


Species-specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults.

Bouvier M, Chen WJ, Arnold JC, Fairchok MP, Danaher PJ, Lalani T, Malone L, Mor D, Ridoré M, Burgess TH, Millar EV.

Influenza Other Respir Viruses. 2018 Mar;12(2):299-303. doi: 10.1111/irv.12538. Epub 2018 Feb 2.


Recurrent Intragenic Duplication within the NR5A1 Gene and Severe Proximal Hypospadias.

Peycelon M, Mansour-Hendili L, Hyon C, Collot N, Houang M, Legendre M, Chabaud M, Bouvier MD, Audry G, Amselem S, Siffroi JP.

Sex Dev. 2017;11(5-6):293-297. doi: 10.1159/000485909. Epub 2018 Jan 13.


Tandem autologous/allogeneic hematopoietic cell transplantation with bortezomib maintenance therapy for high-risk myeloma.

Green DJ, Maloney DG, Storer BE, Sandmaier BM, Holmberg LA, Becker PS, Fang M, Martin PJ, Georges GE, Bouvier ME, Storb R, Mielcarek M.

Blood Adv. 2017 Nov 9;1(24):2247-2256. doi: 10.1182/bloodadvances.2017010686. eCollection 2017 Nov 14.


High-resolution anorectal manometry may probably be worth every penny.

Vitton V, Benezech A, Bouvier M.

Neurogastroenterol Motil. 2018 Jan;30(1). doi: 10.1111/nmo.13217. No abstract available.


Supplemental Content

Loading ...
Support Center