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Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist.

Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BK.

Nat Chem Biol. 2018 Nov 30. doi: 10.1038/s41589-018-0182-5. [Epub ahead of print]


Large-Scale Measurement of mRNA Degradation in Escherichia coli: To Delay or Not to Delay.

Laguerre S, González I, Nouaille S, Moisan A, Villa-Vialaneix N, Gaspin C, Bouvier M, Carpousis AJ, Cocaign-Bousquet M, Girbal L.

Methods Enzymol. 2018;612:47-66. doi: 10.1016/bs.mie.2018.07.003. Epub 2018 Aug 29.


FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs.

Wright SC, Cañizal MCA, Benkel T, Simon K, Le Gouill C, Matricon P, Namkung Y, Lukasheva V, König GM, Laporte SA, Carlsson J, Kostenis E, Bouvier M, Schulte G, Hoffmann C.

Sci Signal. 2018 Dec 4;11(559). pii: eaar5536. doi: 10.1126/scisignal.aar5536.


Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors.

Namkung Y, LeGouill C, Kumar S, Cao Y, Teixeira LB, Lukasheva V, Giubilaro J, Simões SC, Longpré JM, Devost D, Hébert TE, Piñeyro G, Leduc R, Costa-Neto CM, Bouvier M, Laporte SA.

Sci Signal. 2018 Dec 4;11(559). pii: eaat1631. doi: 10.1126/scisignal.aat1631.


Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion.

Hamoud N, Tran V, Aimi T, Kakegawa W, Lahaie S, Thibault MP, Pelletier A, Wong GW, Kim IS, Kania A, Yuzaki M, Bouvier M, Côté JF.

Nat Commun. 2018 Oct 26;9(1):4470. doi: 10.1038/s41467-018-06897-5.


Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist.

Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, Kobilka BK.

Nat Chem Biol. 2018 Nov;14(11):1059-1066. doi: 10.1038/s41589-018-0145-x. Epub 2018 Oct 16.


Translating biased signaling in the ghrelin receptor system into differential in vivo functions.

Mende F, Hundahl C, Plouffe B, Skov LJ, Sivertsen B, Madsen AN, Lückmann M, Diep TA, Offermanns S, Frimurer TM, Bouvier M, Holst B.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10255-E10264. doi: 10.1073/pnas.1804003115. Epub 2018 Oct 9.


Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes.

Picard LP, Schönegge AM, Lohse MJ, Bouvier M.

Commun Biol. 2018 Aug 7;1:106. doi: 10.1038/s42003-018-0101-z. eCollection 2018.


Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9.

Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, Shenoy SK, Laporte SA, Rockman HA, Lefkowitz RJ.

Sci Signal. 2018 Sep 25;11(549). pii: eaat7650. doi: 10.1126/scisignal.aat7650.


Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling.

Karamitri A, Plouffe B, Bonnefond A, Chen M, Gallion J, Guillaume JL, Hegron A, Boissel M, Canouil M, Langenberg C, Wareham NJ, Le Gouill C, Lukasheva V, Lichtarge O, Froguel P, Bouvier M, Jockers R.

Sci Signal. 2018 Aug 28;11(545). pii: eaan6622. doi: 10.1126/scisignal.aan6622.


Discovery of small molecule inhibitors of adenovirus by disrupting E3-19K/HLA-A2 interactions.

Ren J, Dsouza NR, Deng H, Lee H, Bouvier M, Johnson ME.

Bioorg Med Chem Lett. 2018 Sep 15;28(17):2837-2841. doi: 10.1016/j.bmcl.2018.07.036. Epub 2018 Jul 29.


Computational design of orthogonal membrane receptor-effector switches for rewiring signaling pathways.

Young M, Dahoun T, Sokrat B, Arber C, Chen KM, Bouvier M, Barth P.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7051-7056. doi: 10.1073/pnas.1718489115. Epub 2018 Jun 18.


Milk Fat Globules Hamper Adhesion of Enterohemorrhagic Escherichia coli to Enterocytes: In Vitro and in Vivo Evidence.

Douëllou T, Galia W, Kerangart S, Marchal T, Milhau N, Bastien R, Bouvier M, Buff S, Montel MC, Sergentet-Thevenot D.

Front Microbiol. 2018 May 15;9:947. doi: 10.3389/fmicb.2018.00947. eCollection 2018.


Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors.

Chaturvedi M, Schilling J, Beautrait A, Bouvier M, Benovic JL, Shukla AK.

Trends Biochem Sci. 2018 Jul;43(7):533-546. doi: 10.1016/j.tibs.2018.04.003. Epub 2018 May 4. Review.


Insights into RNA-processing pathways and associated RNA-degrading enzymes in Archaea.

Clouet-d'Orval B, Batista M, Bouvier M, Quentin Y, Fichant G, Marchfelder A, Maier LK.

FEMS Microbiol Rev. 2018 Sep 1;42(5):579-613. doi: 10.1093/femsre/fuy016.


Indeterminate genotypes of hepatitis C virus by the Abbott RealTime HCV Genotype II assay in Morocco. About eight cases resolved by a sequencing method.

Mesbahi Z, Kabbaj H, Malki H, Bouihat N, Qrafli M, Belefquih B, Marcil S, Challine D, Pawlotsky JM, Bouvier M, Seffar M.

J Med Virol. 2018 Aug;90(8):1352-1357. doi: 10.1002/jmv.25191. Epub 2018 Apr 26.


Monitoring ligand-dependent assembly of receptor ternary complexes in live cells by BRETFect.

Cotnoir-White D, El Ezzy M, Boulay PL, Rozendaal M, Bouvier M, Gagnon E, Mader S.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2653-E2662. doi: 10.1073/pnas.1716224115. Epub 2018 Feb 27.


Effects of haloperidol and clozapine on synapse-related gene expression in specific brain regions of male rats.

von Wilmsdorff M, Manthey F, Bouvier ML, Staehlin O, Falkai P, Meisenzahl-Lechner E, Schmitt A, Gebicke-Haerter PJ.

Eur Arch Psychiatry Clin Neurosci. 2018 Sep;268(6):555-563. doi: 10.1007/s00406-018-0872-8. Epub 2018 Feb 5.


Species-specific clinical characteristics of human coronavirus infection among otherwise healthy adolescents and adults.

Bouvier M, Chen WJ, Arnold JC, Fairchok MP, Danaher PJ, Lalani T, Malone L, Mor D, Ridoré M, Burgess TH, Millar EV.

Influenza Other Respir Viruses. 2018 Mar;12(2):299-303. doi: 10.1111/irv.12538. Epub 2018 Feb 2.


Recurrent Intragenic Duplication within the NR5A1 Gene and Severe Proximal Hypospadias.

Peycelon M, Mansour-Hendili L, Hyon C, Collot N, Houang M, Legendre M, Chabaud M, Bouvier MD, Audry G, Amselem S, Siffroi JP.

Sex Dev. 2017;11(5-6):293-297. doi: 10.1159/000485909. Epub 2018 Jan 13.


Tandem autologous/allogeneic hematopoietic cell transplantation with bortezomib maintenance therapy for high-risk myeloma.

Green DJ, Maloney DG, Storer BE, Sandmaier BM, Holmberg LA, Becker PS, Fang M, Martin PJ, Georges GE, Bouvier ME, Storb R, Mielcarek M.

Blood Adv. 2017 Nov 9;1(24):2247-2256. doi: 10.1182/bloodadvances.2017010686. eCollection 2017 Nov 14.


High-resolution anorectal manometry may probably be worth every penny.

Vitton V, Benezech A, Bouvier M.

Neurogastroenterol Motil. 2018 Jan;30(1). doi: 10.1111/nmo.13217. No abstract available.


Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity.

Schönegge AM, Gallion J, Picard LP, Wilkins AD, Le Gouill C, Audet M, Stallaert W, Lohse MJ, Kimmel M, Lichtarge O, Bouvier M.

Nat Commun. 2017 Dec 18;8(1):2169. doi: 10.1038/s41467-017-02257-x.


Comparison of Abbott Architect®, Siemens Immulite®, and Diasorin Liaison® for determination of Epstein-Barr virus serological diagnosis.

François C, Segard C, Bouvier M, Stefanski M, Pannier C, Zawadzki P, Roussel C, Hecquet D, Duverlie G, Brochot E, Castelain S.

Diagn Microbiol Infect Dis. 2018 Feb;90(2):96-101. doi: 10.1016/j.diagmicrobio.2017.10.020. Epub 2017 Nov 7.


Pharmacological Characterization of 5-Substituted 1-[(2,3-dihydro-1-benzofuran-2-yl)methyl]piperazines: Novel Antagonists for the Histamine H3 and H4 Receptors with Anti-inflammatory Potential.

Corrêa MF, Barbosa ÁJR, Teixeira LB, Duarte DA, Simões SC, Parreiras-E-Silva LT, Balbino AM, Landgraf RG, Bouvier M, Costa-Neto CM, Fernandes JPS.

Front Pharmacol. 2017 Nov 14;8:825. doi: 10.3389/fphar.2017.00825. eCollection 2017.


Comparative Evaluation of a Novel Phage Protein Ligand Assay and Immunomagnetic Separation Method To Isolate the Seven Top Serogroups of Escherichia coli (O157, O26, O103, O145, O111, O45, and O121) in Foods at Risk.

Bouvier M, Miszczycha SD, Guillarme X, Tadla C, Collinet L, Sergentet DT.

J Food Prot. 2017 Dec;80(12):1973-1979. doi: 10.4315/0362-028X.JFP-16-479.


Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing.

Ehrlich AT, Semache M, Bailly J, Wojcik S, Arefin TM, Colley C, Le Gouill C, Gross F, Lukasheva V, Hogue M, Darcq E, Harsan LA, Bouvier M, Kieffer BL.

Brain Struct Funct. 2018 Apr;223(3):1275-1296. doi: 10.1007/s00429-017-1547-3. Epub 2017 Nov 6.


Prevalence of Fecal Incontinence in Adults with Cystic Fibrosis.

Benezech A, Desmazes-Dufeu N, Baumstarck K, Bouvier M, Coltey B, Reynaud-Gaubert M, Vitton V.

Dig Dis Sci. 2018 Apr;63(4):982-988. doi: 10.1007/s10620-017-4825-2. Epub 2017 Oct 30.


Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy.

Teixeira LB, Parreiras-E-Silva LT, Bruder-Nascimento T, Duarte DA, Simões SC, Costa RM, Rodríguez DY, Ferreira PAB, Silva CAA, Abrao EP, Oliveira EB, Bouvier M, Tostes RC, Costa-Neto CM.

Sci Rep. 2017 Sep 19;7(1):11903. doi: 10.1038/s41598-017-12074-3.


Use of airborne lidar data to improve plant species richness and diversity monitoring in lowland and mountain forests.

Bouvier M, Durrieu S, Gosselin F, Herpigny B.

PLoS One. 2017 Sep 13;12(9):e0184524. doi: 10.1371/journal.pone.0184524. eCollection 2017.


Functional New World monkey oxytocin forms elicit an altered signaling profile and promotes parental care in rats.

Parreiras-E-Silva LT, Vargas-Pinilla P, Duarte DA, Longo D, Espinoza Pardo GV, Dulor Finkler A, Paixão-Côrtes VR, Paré P, Rovaris DL, Oliveira EB, Caceres RA, Gonçalves GL, Bouvier M, Salzano FM, Lucion AB, Costa-Neto CM, Bortolini MC.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9044-9049. doi: 10.1073/pnas.1711687114. Epub 2017 Aug 7.


A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling.

Beautrait A, Paradis JS, Zimmerman B, Giubilaro J, Nikolajev L, Armando S, Kobayashi H, Yamani L, Namkung Y, Heydenreich FM, Khoury E, Audet M, Roux PP, Veprintsev DB, Laporte SA, Bouvier M.

Nat Commun. 2017 Apr 18;8:15054. doi: 10.1038/ncomms15054.


Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

Sokolina K, Kittanakom S, Snider J, Kotlyar M, Maurice P, Gandía J, Benleulmi-Chaachoua A, Tadagaki K, Oishi A, Wong V, Malty RH, Deineko V, Aoki H, Amin S, Yao Z, Morató X, Otasek D, Kobayashi H, Menendez J, Auerbach D, Angers S, Pržulj N, Bouvier M, Babu M, Ciruela F, Jockers R, Jurisica I, Stagljar I.

Mol Syst Biol. 2017 Mar 15;13(3):918. doi: 10.15252/msb.20167430.


Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca2+ in Nonexcitable Cells.

Stallaert W, van der Westhuizen ET, Schönegge AM, Plouffe B, Hogue M, Lukashova V, Inoue A, Ishida S, Aoki J, Le Gouill C, Bouvier M.

Mol Pharmacol. 2017 May;91(5):533-544. doi: 10.1124/mol.116.106419. Epub 2017 Mar 9.


3D High-definition anorectal manometry: Values obtained in asymptomatic volunteers, fecal incontinence and chronic constipation. Results of a prospective multicenter study (NOMAD).

Mion F, Garros A, Brochard C, Vitton V, Ropert A, Bouvier M, Damon H, Siproudhis L, Roman S.

Neurogastroenterol Motil. 2017 Aug;29(8). doi: 10.1111/nmo.13049. Epub 2017 Mar 2.


Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure.

Möller D, Banerjee A, Uzuneser TC, Skultety M, Huth T, Plouffe B, Hübner H, Alzheimer C, Friedland K, Müller CP, Bouvier M, Gmeiner P.

J Med Chem. 2017 Apr 13;60(7):2908-2929. doi: 10.1021/acs.jmedchem.6b01857. Epub 2017 Mar 22.


Predicting phenotype from genotype: Improving accuracy through more robust experimental and computational modeling.

Gallion J, Koire A, Katsonis P, Schoenegge AM, Bouvier M, Lichtarge O.

Hum Mutat. 2017 May;38(5):569-580. doi: 10.1002/humu.23193. Epub 2017 Feb 28.


Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis.

Cahill TJ 3rd, Thomsen AR, Tarrasch JT, Plouffe B, Nguyen AH, Yang F, Huang LY, Kahsai AW, Bassoni DL, Gavino BJ, Lamerdin JE, Triest S, Shukla AK, Berger B, Little J 4th, Antar A, Blanc A, Qu CX, Chen X, Kawakami K, Inoue A, Aoki J, Steyaert J, Sun JP, Bouvier M, Skiniotis G, Lefkowitz RJ.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2562-2567. doi: 10.1073/pnas.1701529114. Epub 2017 Feb 21.


Targeting a Proteinase-Activated Receptor 4 (PAR4) Carboxyl Terminal Motif to Regulate Platelet Function.

Ramachandran R, Mihara K, Thibeault P, Vanderboor CM, Petri B, Saifeddine M, Bouvier M, Hollenberg MD.

Mol Pharmacol. 2017 Apr;91(4):287-295. doi: 10.1124/mol.116.106526. Epub 2017 Jan 26.


Blockade of protease-activated receptor-4 (PAR4) provides robust antithrombotic activity with low bleeding.

Wong PC, Seiffert D, Bird JE, Watson CA, Bostwick JS, Giancarli M, Allegretto N, Hua J, Harden D, Guay J, Callejo M, Miller MM, Lawrence RM, Banville J, Guy J, Maxwell BD, Priestley ES, Marinier A, Wexler RR, Bouvier M, Gordon DA, Schumacher WA, Yang J.

Sci Transl Med. 2017 Jan 4;9(371). pii: eaaf5294. doi: 10.1126/scitranslmed.aaf5294.


KCTD Hetero-oligomers Confer Unique Kinetic Properties on Hippocampal GABAB Receptor-Induced K+ Currents.

Fritzius T, Turecek R, Seddik R, Kobayashi H, Tiao J, Rem PD, Metz M, Kralikova M, Bouvier M, Gassmann M, Bettler B.

J Neurosci. 2017 Feb 1;37(5):1162-1175. doi: 10.1523/JNEUROSCI.2181-16.2016. Epub 2016 Dec 21.


Rectal intussusception: can high resolution three-dimensional ano-rectal manometry compete with conventional defecography?

Benezech A, Cappiello M, Baumstarck K, Grimaud JC, Bouvier M, Vitton V.

Neurogastroenterol Motil. 2017 Apr;29(4). doi: 10.1111/nmo.12978. Epub 2016 Nov 27.


Older adults with heart failure treated with carvedilol, bisoprolol, or metoprolol tartrate: risk of mortality.

Perreault S, de Denus S, White M, White-Guay B, Bouvier M, Dorais M, Dubé MP, Rouleau JL, Tardif JC, Jenna S, Haibe-Kains B, Leduc R, Deblois D.

Pharmacoepidemiol Drug Saf. 2017 Jan;26(1):81-90. doi: 10.1002/pds.4132. Epub 2016 Nov 16.


A Pluridimensional View of Biased Agonism.

Costa-Neto CM, Parreiras-E-Silva LT, Bouvier M.

Mol Pharmacol. 2016 Nov;90(5):587-595. Epub 2016 Sep 16. Review.


Esophageal and anorectal involvement in systemic sclerosis: a systematic assessment with high resolution manometry.

Luciano L, Granel B, Bernit E, Harle JR, Baumstarck K, Grimaud JC, Bouvier M, Vitton V.

Clin Exp Rheumatol. 2016 Sep-Oct;34 Suppl 100(5):63-69. Epub 2016 May 24.


European Survey on Adverse Systemic Reactions in Allergen Immunotherapy (EASSI): a real-life clinical assessment.

Calderón MA, Vidal C, Rodríguez Del Río P, Just J, Pfaar O, Tabar AI, Sánchez-Machín I, Bubel P, Borja J, Eberle P, Reiber R, Bouvier M, Lepelliez A, Klimek L, Demoly P; EASSI Doctors' Group.

Allergy. 2017 Mar;72(3):462-472. doi: 10.1111/all.13066. Epub 2016 Nov 10.


Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region.

Venkatakrishnan AJ, Deupi X, Lebon G, Heydenreich FM, Flock T, Miljus T, Balaji S, Bouvier M, Veprintsev DB, Tate CG, Schertler GF, Babu MM.

Nature. 2016 Aug 25;536(7617):484-7. Epub 2016 Aug 15.


ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing.

Chen H, Li L, Weimershaus M, Evnouchidou I, van Endert P, Bouvier M.

Sci Rep. 2016 Aug 12;6:28902. doi: 10.1038/srep28902.


GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.

Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ.

Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4.


Intense THz Pulses with large ponderomotive potential generated from large aperture photoconductive antennas.

Ropagnol X, Khorasaninejad M, Raeiszadeh M, Safavi-Naeini S, Bouvier M, Côté CY, Laramée A, Reid M, Gauthier MA, Ozaki T.

Opt Express. 2016 May 30;24(11):11299-311. doi: 10.1364/OE.24.011299.


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