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Items: 12

1.

CDK12 regulates DNA repair genes by suppressing intronic polyadenylation.

Dubbury SJ, Boutz PL, Sharp PA.

Nature. 2018 Dec;564(7734):141-145. doi: 10.1038/s41586-018-0758-y. Epub 2018 Nov 28.

2.

Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors.

Martin SES, Tan ZW, Itkonen HM, Duveau DY, Paulo JA, Janetzko J, Boutz PL, Törk L, Moss FA, Thomas CJ, Gygi SP, Lazarus MB, Walker S.

J Am Chem Soc. 2018 Oct 24;140(42):13542-13545. doi: 10.1021/jacs.8b07328. Epub 2018 Oct 4.

3.

Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow.

Murphy PA, Butty VL, Boutz PL, Begum S, Kimble AL, Sharp PA, Burge CB, Hynes RO.

Elife. 2018 Jan 2;7. pii: e29494. doi: 10.7554/eLife.29494.

4.

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.

Braun CJ, Stanciu M, Boutz PL, Patterson JC, Calligaris D, Higuchi F, Neupane R, Fenoglio S, Cahill DP, Wakimoto H, Agar NYR, Yaffe MB, Sharp PA, Hemann MT, Lees JA.

Cancer Cell. 2017 Oct 9;32(4):411-426.e11. doi: 10.1016/j.ccell.2017.08.018. Epub 2017 Sep 28.

5.

Detained introns are a novel, widespread class of post-transcriptionally spliced introns.

Boutz PL, Bhutkar A, Sharp PA.

Genes Dev. 2015 Jan 1;29(1):63-80. doi: 10.1101/gad.247361.114.

6.

Rbfox2 controls autoregulation in RNA-binding protein networks.

Jangi M, Boutz PL, Paul P, Sharp PA.

Genes Dev. 2014 Mar 15;28(6):637-51. doi: 10.1101/gad.235770.113.

7.

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.

Boutz PL, Stoilov P, Li Q, Lin CH, Chawla G, Ostrow K, Shiue L, Ares M Jr, Black DL.

Genes Dev. 2007 Jul 1;21(13):1636-52.

8.

MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development.

Boutz PL, Chawla G, Stoilov P, Black DL.

Genes Dev. 2007 Jan 1;21(1):71-84.

9.

Homologues of the Caenorhabditis elegans Fox-1 protein are neuronal splicing regulators in mammals.

Underwood JG, Boutz PL, Dougherty JD, Stoilov P, Black DL.

Mol Cell Biol. 2005 Nov;25(22):10005-16.

10.

Exon repression by polypyrimidine tract binding protein.

Amir-Ahmady B, Boutz PL, Markovtsov V, Phillips ML, Black DL.

RNA. 2005 May;11(5):699-716.

11.

Influenza virus nucleoprotein interacts with influenza virus polymerase proteins.

Biswas SK, Boutz PL, Nayak DP.

J Virol. 1998 Jul;72(7):5493-501.

12.

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