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Items: 1 to 50 of 85

1.

The immune system profoundly restricts intratumor genetic heterogeneity.

Milo I, Bedora-Faure M, Garcia Z, Thibaut R, Périé L, Shakhar G, Deriano L, Bousso P.

Sci Immunol. 2018 Nov 23;3(29). pii: eaat1435. doi: 10.1126/sciimmunol.aat1435.

PMID:
30470696
2.

CD11c-expressing Ly6C+CCR2+ monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmission.

Heyde S, Philipsen L, Formaglio P, Fu Y, Baars I, Höbbel G, Kleinholz CL, Seiß EA, Stettin J, Gintschel P, Dudeck A, Bousso P, Schraven B, Müller AJ.

PLoS Pathog. 2018 Oct 22;14(10):e1007374. doi: 10.1371/journal.ppat.1007374. eCollection 2018 Oct.

3.

A Metabolism-Based Quorum Sensing Mechanism Contributes to Termination of Inflammatory Responses.

Postat J, Olekhnovitch R, Lemaître F, Bousso P.

Immunity. 2018 Oct 16;49(4):654-665.e5. doi: 10.1016/j.immuni.2018.07.014. Epub 2018 Sep 25.

PMID:
30266340
4.

A human immune system mouse model with robust lymph node development.

Li Y, Masse-Ranson G, Garcia Z, Bruel T, Kök A, Strick-Marchand H, Jouvion G, Serafini N, Lim AI, Dusseaux M, Hieu T, Bourgade F, Toubert A, Finke D, Schwartz O, Bousso P, Mouquet H, Di Santo JP.

Nat Methods. 2018 Aug;15(8):623-630. doi: 10.1038/s41592-018-0071-6. Epub 2018 Jul 31.

PMID:
30065364
5.

The bone marrow is patrolled by NK cells that are primed and expand in response to systemic viral activation.

Milo I, Blecher-Gonen R, Barnett-Itzhaki Z, Bar-Ziv R, Tal O, Gurevich I, Feferman T, Drexler I, Amit I, Bousso P, Shakhar G.

Eur J Immunol. 2018 Jul;48(7):1137-1152. doi: 10.1002/eji.201747378. Epub 2018 May 2.

PMID:
29624673
6.

Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division.

Bohineust A, Garcia Z, Beuneu H, Lemaître F, Bousso P.

J Exp Med. 2018 May 7;215(5):1481-1492. doi: 10.1084/jem.20171708. Epub 2018 Mar 27.

7.

CXCR3/CXCL10 Axis Shapes Tissue Distribution of Memory Phenotype CD8+ T Cells in Nonimmunized Mice.

Alanio C, Barreira da Silva R, Michonneau D, Bousso P, Ingersoll MA, Albert ML.

J Immunol. 2018 Jan 1;200(1):139-146. doi: 10.4049/jimmunol.1700564. Epub 2017 Nov 29.

PMID:
29187588
8.

In Vivo Imaging of T Cell Immunological Synapses and Kinapses in Lymph Nodes.

Moreau HD, Bousso P.

Methods Mol Biol. 2017;1584:559-568. doi: 10.1007/978-1-4939-6881-7_35.

PMID:
28255726
9.

Microchannels for the Study of T Cell Immunological Synapses and Kinapses.

Moreau HD, Bousso P, Lennon-Duménil AM.

Methods Mol Biol. 2017;1584:347-354. doi: 10.1007/978-1-4939-6881-7_20.

PMID:
28255711
10.

S1P1 downregulation tailors CD8+ T-cell residence time in lymph nodes to the strength of the antigenic stimulation.

Breart B, Bousso P.

Eur J Immunol. 2016 Dec;46(12):2730-2736. doi: 10.1002/eji.201646550. Epub 2016 Nov 2.

11.

In vivo effector functions of high-affinity mouse IgG receptor FcγRI in disease and therapy models.

Gillis CM, Zenatti PP, Mancardi DA, Beutier H, Fiette L, Macdonald LE, Murphy AJ, Celli S, Bousso P, Jönsson F, Bruhns P.

J Autoimmun. 2017 Jun;80:95-102. doi: 10.1016/j.jaut.2016.09.009. Epub 2016 Oct 10.

12.

Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies.

Grandjean CL, Montalvao F, Celli S, Michonneau D, Breart B, Garcia Z, Perro M, Freytag O, Gerdes CA, Bousso P.

Sci Rep. 2016 Oct 4;6:34382. doi: 10.1038/srep34382.

13.

Élie Metchnikoff (1845-1916): celebrating 100 years of cellular immunology and beyond.

Underhill DM, Gordon S, Imhof BA, Núñez G, Bousso P.

Nat Rev Immunol. 2016 Oct;16(10):651-6. doi: 10.1038/nri.2016.89. Epub 2016 Aug 1. Review.

PMID:
27477126
14.

A virtual lymph node model to dissect the requirements for T-cell activation by synapses and kinapses.

Moreau HD, Bogle G, Bousso P.

Immunol Cell Biol. 2016 Aug;94(7):680-8. doi: 10.1038/icb.2016.36. Epub 2016 May 10.

15.

Manipulating leukocyte interactions in vivo through optogenetic chemokine release.

Sarris M, Olekhnovitch R, Bousso P.

Blood. 2016 Jun 9;127(23):e35-41. doi: 10.1182/blood-2015-11-684852. Epub 2016 Apr 7.

16.

The PD-1 Axis Enforces an Anatomical Segregation of CTL Activity that Creates Tumor Niches after Allogeneic Hematopoietic Stem Cell Transplantation.

Michonneau D, Sagoo P, Breart B, Garcia Z, Celli S, Bousso P.

Immunity. 2016 Jan 19;44(1):143-154. doi: 10.1016/j.immuni.2015.12.008. Epub 2016 Jan 12.

17.

In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity.

Sagoo P, Garcia Z, Breart B, Lemaître F, Michonneau D, Albert ML, Levy Y, Bousso P.

Nat Med. 2016 Jan;22(1):64-71. doi: 10.1038/nm.4016. Epub 2015 Dec 21.

18.

Induction, Propagation, and Activity of Host Nitric Oxide: Lessons from Leishmania Infection.

Olekhnovitch R, Bousso P.

Trends Parasitol. 2015 Dec;31(12):653-664. doi: 10.1016/j.pt.2015.08.001. Epub 2015 Oct 1. Review.

PMID:
26440786
19.

Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest.

Moreau HD, Lemaître F, Garrod KR, Garcia Z, Lennon-Duménil AM, Bousso P.

Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):12151-6. doi: 10.1073/pnas.1506654112. Epub 2015 Sep 14.

20.

Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors.

Mendes-da-Cruz DA, Brignier AC, Asnafi V, Baleydier F, Messias CV, Lepelletier Y, Bedjaoui N, Renand A, Smaniotto S, Canioni D, Milpied P, Balabanian K, Bousso P, Leprêtre S, Bertrand Y, Dombret H, Ifrah N, Dardenne M, Macintyre E, Savino W, Hermine O.

PLoS One. 2014 Jul 28;9(7):e103405. doi: 10.1371/journal.pone.0103405. eCollection 2014.

21.

Collective nitric oxide production provides tissue-wide immunity during Leishmania infection.

Olekhnovitch R, Ryffel B, Müller AJ, Bousso P.

J Clin Invest. 2014 Apr;124(4):1711-22. doi: 10.1172/JCI72058. Epub 2014 Mar 10.

22.

Visualizing how T cells collect activation signals in vivo.

Moreau HD, Bousso P.

Curr Opin Immunol. 2014 Feb;26:56-62. doi: 10.1016/j.coi.2013.10.013. Epub 2013 Nov 24. Review.

PMID:
24556401
23.

The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imaging.

Montalvao F, Garcia Z, Celli S, Breart B, Deguine J, Van Rooijen N, Bousso P.

J Clin Invest. 2013 Dec;123(12):5098-103. doi: 10.1172/JCI70972. Epub 2013 Nov 1.

24.

Photoconvertible pathogen labeling reveals nitric oxide control of Leishmania major infection in vivo via dampening of parasite metabolism.

Müller AJ, Aeschlimann S, Olekhnovitch R, Dacher M, Späth GF, Bousso P.

Cell Host Microbe. 2013 Oct 16;14(4):460-7. doi: 10.1016/j.chom.2013.09.008.

25.

Phenotypic CD8+ T cell diversification occurs before, during, and after the first T cell division.

Lemaître F, Moreau HD, Vedele L, Bousso P.

J Immunol. 2013 Aug 15;191(4):1578-85. doi: 10.4049/jimmunol.1300424. Epub 2013 Jul 8.

26.

Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation.

Guenin-Macé L, Veyron-Churlet R, Thoulouze MI, Romet-Lemonne G, Hong H, Leadlay PF, Danckaert A, Ruf MT, Mostowy S, Zurzolo C, Bousso P, Chrétien F, Carlier MF, Demangel C.

J Clin Invest. 2013 Apr;123(4):1501-12. doi: 10.1172/JCI66576. Epub 2013 Mar 15.

27.

Shigella impairs T lymphocyte dynamics in vivo.

Salgado-Pabón W, Celli S, Arena ET, Nothelfer K, Roux P, Sellge G, Frigimelica E, Bousso P, Sansonetti PJ, Phalipon A.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4458-63. doi: 10.1073/pnas.1300981110. Epub 2013 Feb 15.

28.

Dynamics of NK cell interactions in vivo.

Deguine J, Bousso P.

Immunol Rev. 2013 Jan;251(1):154-9. doi: 10.1111/imr.12015. Review.

PMID:
23278747
29.

Cutting edge: tumor-targeting antibodies enhance NKG2D-mediated NK cell cytotoxicity by stabilizing NK cell-tumor cell interactions.

Deguine J, Breart B, Lemaître F, Bousso P.

J Immunol. 2012 Dec 15;189(12):5493-7. doi: 10.4049/jimmunol.1202065. Epub 2012 Nov 26.

30.

Functional immunoimaging: the revolution continues.

Bousso P, Moreau HD.

Nat Rev Immunol. 2012 Dec;12(12):858-64. doi: 10.1038/nri3342. Review.

PMID:
23175230
31.

Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis.

Garrod KR, Moreau HD, Garcia Z, Lemaître F, Bouvier I, Albert ML, Bousso P.

Cell Rep. 2012 Nov 29;2(5):1438-47. doi: 10.1016/j.celrep.2012.10.015. Epub 2012 Nov 15.

32.

Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory.

Pace L, Tempez A, Arnold-Schrauf C, Lemaitre F, Bousso P, Fetler L, Sparwasser T, Amigorena S.

Science. 2012 Oct 26;338(6106):532-6. doi: 10.1126/science.1227049.

33.

Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles.

Garcia Z, Lemaître F, van Rooijen N, Albert ML, Levy Y, Schwartz O, Bousso P.

Blood. 2012 Dec 6;120(24):4744-50. doi: 10.1182/blood-2012-02-408179. Epub 2012 Oct 12.

34.

How many dendritic cells are required to initiate a T-cell response?

Celli S, Day M, Müller AJ, Molina-Paris C, Lythe G, Bousso P.

Blood. 2012 Nov 8;120(19):3945-8. doi: 10.1182/blood-2012-01-408260. Epub 2012 Sep 20.

35.

CD4+ T cells rely on a cytokine gradient to control intracellular pathogens beyond sites of antigen presentation.

Müller AJ, Filipe-Santos O, Eberl G, Aebischer T, Späth GF, Bousso P.

Immunity. 2012 Jul 27;37(1):147-57. doi: 10.1016/j.immuni.2012.05.015. Epub 2012 Jun 21.

36.

Mathematical model of tumor immunotherapy for bladder carcinoma identifies the limitations of the innate immune response.

Breban R, Bisiaux A, Biot C, Rentsch C, Bousso P, Albert ML.

Oncoimmunology. 2012 Jan 1;1(1):9-17.

37.

Dynamic in situ cytometry uncovers T cell receptor signaling during immunological synapses and kinapses in vivo.

Moreau HD, Lemaître F, Terriac E, Azar G, Piel M, Lennon-Dumenil AM, Bousso P.

Immunity. 2012 Aug 24;37(2):351-63. doi: 10.1016/j.immuni.2012.05.014. Epub 2012 Jun 7.

38.

Preexisting BCG-specific T cells improve intravesical immunotherapy for bladder cancer.

Biot C, Rentsch CA, Gsponer JR, Birkhäuser FD, Jusforgues-Saklani H, Lemaître F, Auriau C, Bachmann A, Bousso P, Demangel C, Peduto L, Thalmann GN, Albert ML.

Sci Transl Med. 2012 Jun 6;4(137):137ra72. doi: 10.1126/scitranslmed.3003586.

39.

Cutting Edge: A dual role for type I IFNs during polyinosinic-polycytidylic acid-induced NK cell activation.

Beuneu H, Deguine J, Bouvier I, Di Santo JP, Albert ML, Bousso P.

J Immunol. 2011 Sep 1;187(5):2084-8. doi: 10.4049/jimmunol.1004210. Epub 2011 Aug 1.

40.

Chronic infections capture little attention of the masses.

Bousso P.

Immunity. 2011 May 27;34(5):699-701. doi: 10.1016/j.immuni.2011.05.005.

41.

Visualizing the innate and adaptive immune responses underlying allograft rejection by two-photon microscopy.

Celli S, Albert ML, Bousso P.

Nat Med. 2011 Jun;17(6):744-9. doi: 10.1038/nm.2376. Epub 2011 May 15.

PMID:
21572426
42.

A role for the immediate early gene product c-fos in imprinting T cells with short-term memory for signal summation.

Clark CE, Hasan M, Bousso P.

PLoS One. 2011 Apr 28;6(4):e18916. doi: 10.1371/journal.pone.0018916.

43.

Immunization route dictates cross-priming efficiency and impacts the optimal timing of adjuvant delivery.

Bouvier I, Jusforgues-Saklani H, Lim A, Lemaître F, Lemercier B, Auriau C, Nicola MA, Leroy S, Law HK, Bandeira A, Moon JJ, Bousso P, Albert ML.

Front Immunol. 2011 Dec 8;2:71. doi: 10.3389/fimmu.2011.00071. eCollection 2011.

44.

Restricted microbiota and absence of cognate TCR antigen leads to an unbalanced generation of Th17 cells.

Lochner M, Bérard M, Sawa S, Hauer S, Gaboriau-Routhiau V, Fernandez TD, Snel J, Bousso P, Cerf-Bensussan N, Eberl G.

J Immunol. 2011 Feb 1;186(3):1531-7. doi: 10.4049/jimmunol.1001723. Epub 2010 Dec 22.

45.

Quantifying subcellular distribution of fluorescent fusion proteins in cells migrating within tissues.

Melichar HJ, Li O, Herzmark P, Padmanabhan RK, Oliaro J, Ludford-Menting MJ, Bousso P, Russell SM, Roysam B, Robey EA.

Immunol Cell Biol. 2011 May;89(4):549-57. doi: 10.1038/icb.2010.122. Epub 2010 Oct 19.

PMID:
20956985
46.

Intravital imaging reveals distinct dynamics for natural killer and CD8(+) T cells during tumor regression.

Deguine J, Breart B, Lemaître F, Di Santo JP, Bousso P.

Immunity. 2010 Oct 29;33(4):632-44. doi: 10.1016/j.immuni.2010.09.016. Epub 2010 Oct 14.

47.

Visualizing the functional diversification of CD8+ T cell responses in lymph nodes.

Beuneu H, Lemaître F, Deguine J, Moreau HD, Bouvier I, Garcia Z, Albert ML, Bousso P.

Immunity. 2010 Sep 24;33(3):412-23. doi: 10.1016/j.immuni.2010.08.016.

48.

Signal 0 for guided priming of CTLs: NKT cells do it too.

Bousso P, Albert ML.

Nat Immunol. 2010 Apr;11(4):284-6. doi: 10.1038/ni0410-284. Review. No abstract available.

PMID:
20300136
49.

Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes.

Azar GA, Lemaître F, Robey EA, Bousso P.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3675-80. doi: 10.1073/pnas.0905901107. Epub 2010 Feb 4.

50.

Dynamic behavior of NK cells during activation in lymph nodes.

Beuneu H, Deguine J, Breart B, Mandelboim O, Di Santo JP, Bousso P.

Blood. 2009 Oct 8;114(15):3227-34. doi: 10.1182/blood-2009-06-228759. Epub 2009 Aug 10.

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