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Items: 16


Synthesis, F-18 radiolabeling, and microPET evaluation of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines as ligands of the corticotropin-releasing factor type-1 (CRF1) receptor.

Stehouwer JS, Birnbaum MS, Voll RJ, Owens MJ, Plott SJ, Bourke CH, Wassef MA, Kilts CD, Goodman MM.

Bioorg Med Chem. 2015 Aug 1;23(15):4286-302. doi: 10.1016/j.bmc.2015.06.036. Epub 2015 Jun 19.


Prenatal stress, regardless of concurrent escitalopram treatment, alters behavior and amygdala gene expression of adolescent female rats.

Ehrlich DE, Neigh GN, Bourke CH, Nemeth CL, Hazra R, Ryan SJ, Rowson S, Jairam N, Sholar CA, Rainnie DG, Stowe ZN, Owens MJ.

Neuropharmacology. 2015 Oct;97:251-8. doi: 10.1016/j.neuropharm.2015.05.012. Epub 2015 May 30.


Striatal dopamine receptor plasticity in neurotensin deficient mice.

Chastain LG, Qu H, Bourke CH, Iuvone PM, Dobner PR, Nemeroff CB, Kinkead B.

Behav Brain Res. 2015 Mar 1;280:160-71. doi: 10.1016/j.bbr.2014.11.014. Epub 2014 Nov 15.


SSRI or CRF antagonism partially ameliorate depressive-like behavior after adolescent social defeat.

Bourke CH, Glasper ER, Neigh GN.

Behav Brain Res. 2014 Aug 15;270:295-9. doi: 10.1016/j.bbr.2014.05.035. Epub 2014 May 24.


Prenatal antidepressant exposure: clinical and preclinical findings.

Bourke CH, Stowe ZN, Owens MJ.

Pharmacol Rev. 2014 Feb 24;66(2):435-65. doi: 10.1124/pr.111.005207. Print 2014. Review.


Prenatal exposure to escitalopram and/or stress in rats produces limited effects on endocrine, behavioral, or gene expression measures in adult male rats.

Bourke CH, Stowe ZN, Neigh GN, Olson DE, Owens MJ.

Neurotoxicol Teratol. 2013 Sep-Oct;39:100-9. doi: 10.1016/ Epub 2013 Jul 30.


Estradiol stimulates an anti-translocation expression pattern of glucocorticoid co-regulators in a hippocampal cell model.

Malviya SA, Kelly SD, Greenlee MM, Eaton DC, Duke BJ, Bourke CH, Neigh GN.

Physiol Behav. 2013 Oct 2;122:187-92. doi: 10.1016/j.physbeh.2013.03.018. Epub 2013 Mar 26.


Prenatal exposure to escitalopram and/or stress in rats: a prenatal stress model of maternal depression and its treatment.

Bourke CH, Capello CF, Rogers SM, Yu ML, Boss-Williams KA, Weiss JM, Stowe ZN, Owens MJ.

Psychopharmacology (Berl). 2013 Jul;228(2):231-41. doi: 10.1007/s00213-013-3030-z. Epub 2013 Feb 24. Erratum in: Psychopharmacology (Berl). 2014 Dec;231(23):4583.


Escitalopram alters gene expression and HPA axis reactivity in rats following chronic overexpression of corticotropin-releasing factor from the central amygdala.

Flandreau EI, Bourke CH, Ressler KJ, Vale WW, Nemeroff CB, Owens MJ.

Psychoneuroendocrinology. 2013 Aug;38(8):1349-61. doi: 10.1016/j.psyneuen.2012.11.020. Epub 2012 Dec 23.


Translational reciprocity: bridging the gap between preclinical studies and clinical treatment of stress effects on the adolescent brain.

Neigh GN, Ritschel LA, Kilpela LS, Harrell CS, Bourke CH.

Neuroscience. 2013 Sep 26;249:139-53. doi: 10.1016/j.neuroscience.2012.09.075. Epub 2012 Oct 13. Review.


Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner.

Bourke CH, Raees MQ, Malviya S, Bradburn CA, Binder EB, Neigh GN.

Psychoneuroendocrinology. 2013 Jan;38(1):84-93. doi: 10.1016/j.psyneuen.2012.05.001. Epub 2012 May 29.


Stress-induced sex differences: adaptations mediated by the glucocorticoid receptor.

Bourke CH, Harrell CS, Neigh GN.

Horm Behav. 2012 Aug;62(3):210-8. doi: 10.1016/j.yhbeh.2012.02.024. Epub 2012 Mar 3. Review.


Exposure to repeated maternal aggression induces depressive-like behavior and increases startle in adult female rats.

Bourke CH, Neigh GN.

Behav Brain Res. 2012 Feb 1;227(1):270-5. doi: 10.1016/j.bbr.2011.11.001. Epub 2011 Nov 9.


Serotonin transporter occupancy in rats exposed to serotonin reuptake inhibitors in utero or via breast milk.

Capello CF, Bourke CH, Ritchie JC, Stowe ZN, Newport DJ, Nemeroff A, Owens MJ.

J Pharmacol Exp Ther. 2011 Oct;339(1):275-85. doi: 10.1124/jpet.111.183855. Epub 2011 Jul 20.


Behavioral effects of chronic adolescent stress are sustained and sexually dimorphic.

Bourke CH, Neigh GN.

Horm Behav. 2011 Jun;60(1):112-20. doi: 10.1016/j.yhbeh.2011.03.011. Epub 2011 Apr 2.

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