Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 74

1.

TRPV1 promotes opioid analgesia during inflammation.

Basso L, Aboushousha R, Fan CY, Iftinca M, Melo H, Flynn R, Agosti F, Hollenberg MD, Thompson R, Bourinet E, Trang T, Altier C.

Sci Signal. 2019 Apr 2;12(575). pii: eaav0711. doi: 10.1126/scisignal.aav0711.

PMID:
30940767
2.

Cav3.2 T-type calcium channels shape electrical firing in mouse Lamina II neurons.

Candelas M, Reynders A, Arango-Lievano M, Neumayer C, Fruquière A, Demes E, Hamid J, Lemmers C, Bernat C, Monteil A, Compan V, Laffray S, Inquimbert P, Le Feuvre Y, Zamponi GW, Moqrich A, Bourinet E, Méry PF.

Sci Rep. 2019 Feb 28;9(1):3112. doi: 10.1038/s41598-019-39703-3.

3.

Inhibition of Cav 3.2 calcium channels: A new target for colonic hypersensitivity associated with low-grade inflammation.

Picard E, Carvalho FA, Agosti F, Bourinet E, Ardid D, Eschalier A, Daulhac L, Mallet C.

Br J Pharmacol. 2019 Apr;176(7):950-963. doi: 10.1111/bph.14608. Epub 2019 Mar 11.

PMID:
30714145
4.

5-HT2A receptor-dependent phosphorylation of mGlu2 receptor at Serine 843 promotes mGlu2 receptor-operated Gi/o signaling.

Murat S, Bigot M, Chapron J, König GM, Kostenis E, Battaglia G, Nicoletti F, Bourinet E, Bockaert J, Marin P, Vandermoere F.

Mol Psychiatry. 2018 Jun 1. doi: 10.1038/s41380-018-0069-6. [Epub ahead of print]

PMID:
29858599
5.

The Low-Threshold Calcium Channel Cav3.2 Mediates Burst Firing of Mature Dentate Granule Cells.

Dumenieu M, Senkov O, Mironov A, Bourinet E, Kreutz MR, Dityatev A, Heine M, Bikbaev A, Lopez-Rojas J.

Cereb Cortex. 2018 Jul 1;28(7):2594-2609. doi: 10.1093/cercor/bhy084.

6.

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.

Song OR, Kim HB, Jouny S, Ricard I, Vandeputte A, Deboosere N, Marion E, Queval CJ, Lesport P, Bourinet E, Henrion D, Oh SB, Lebon G, Sandoz G, Yeramian E, Marsollier L, Brodin P.

Toxins (Basel). 2017 Jul 18;9(7). pii: E227. doi: 10.3390/toxins9070227.

7.

Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain.

Ventéo S, Laffray S, Wetzel C, Rivat C, Scamps F, Méchaly I, Bauchet L, Raoul C, Bourinet E, Lewin GR, Carroll P, Pattyn A.

Sci Rep. 2016 Nov 2;6:36407. doi: 10.1038/srep36407.

8.

Block of voltage-gated calcium channels by peptide toxins.

Bourinet E, Zamponi GW.

Neuropharmacology. 2017 Dec;127:109-115. doi: 10.1016/j.neuropharm.2016.10.016. Epub 2016 Oct 15. Review.

PMID:
27756538
9.

Genetic alteration of the metal/redox modulation of Cav3.2 T-type calcium channel reveals its role in neuronal excitability.

Voisin T, Bourinet E, Lory P.

J Physiol. 2016 Jul 1;594(13):3561-74. doi: 10.1113/JP271925. Epub 2016 May 7.

10.

T-type calcium channels in neuropathic pain.

Bourinet E, Francois A, Laffray S.

Pain. 2016 Feb;157 Suppl 1:S15-22. doi: 10.1097/j.pain.0000000000000469. Review.

PMID:
26785151
11.

Transcriptional Profiling of Cutaneous MRGPRD Free Nerve Endings and C-LTMRs.

Reynders A, Mantilleri A, Malapert P, Rialle S, Nidelet S, Laffray S, Beurrier C, Bourinet E, Moqrich A.

Cell Rep. 2015 Feb 17;10(6):1007-1019. doi: 10.1016/j.celrep.2015.01.022. Epub 2015 Feb 13.

12.

The Low-Threshold Calcium Channel Cav3.2 Determines Low-Threshold Mechanoreceptor Function.

François A, Schüetter N, Laffray S, Sanguesa J, Pizzoccaro A, Dubel S, Mantilleri A, Nargeot J, Noël J, Wood JN, Moqrich A, Pongs O, Bourinet E.

Cell Rep. 2015 Jan 20;10(3):370-382. doi: 10.1016/j.celrep.2014.12.042. Epub 2015 Jan 15.

13.

GINIP, a Gαi-interacting protein, functions as a key modulator of peripheral GABAB receptor-mediated analgesia.

Gaillard S, Lo Re L, Mantilleri A, Hepp R, Urien L, Malapert P, Alonso S, Deage M, Kambrun C, Landry M, Low SA, Alloui A, Lambolez B, Scherrer G, Le Feuvre Y, Bourinet E, Moqrich A.

Neuron. 2014 Oct 1;84(1):123-136. doi: 10.1016/j.neuron.2014.08.056. Epub 2014 Sep 18.

14.

Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception.

Pereira V, Busserolles J, Christin M, Devilliers M, Poupon L, Legha W, Alloui A, Aissouni Y, Bourinet E, Lesage F, Eschalier A, Lazdunski M, Noël J.

Pain. 2014 Dec;155(12):2534-44. doi: 10.1016/j.pain.2014.09.013. Epub 2014 Sep 18.

PMID:
25239074
15.

The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity.

García-Caballero A, Gadotti VM, Stemkowski P, Weiss N, Souza IA, Hodgkinson V, Bladen C, Chen L, Hamid J, Pizzoccaro A, Deage M, François A, Bourinet E, Zamponi GW.

Neuron. 2014 Sep 3;83(5):1144-58. doi: 10.1016/j.neuron.2014.07.036.

16.

T-type calcium channel Cav3.2 deficient mice show elevated anxiety, impaired memory and reduced sensitivity to psychostimulants.

Gangarossa G, Laffray S, Bourinet E, Valjent E.

Front Behav Neurosci. 2014 Mar 18;8:92. doi: 10.3389/fnbeh.2014.00092. eCollection 2014.

17.

T-type calcium channels in chronic pain: mouse models and specific blockers.

François A, Laffray S, Pizzoccaro A, Eschalier A, Bourinet E.

Pflugers Arch. 2014 Apr;466(4):707-17. doi: 10.1007/s00424-014-1484-4. Epub 2014 Mar 4. Review.

PMID:
24590509
18.

Ca(v)3.2 calcium channels: the key protagonist in the supraspinal effect of paracetamol.

Kerckhove N, Mallet C, François A, Boudes M, Chemin J, Voets T, Bourinet E, Alloui A, Eschalier A.

Pain. 2014 Apr;155(4):764-72. doi: 10.1016/j.pain.2014.01.015. Epub 2014 Jan 18.

PMID:
24447516
19.

Calcium-permeable ion channels in pain signaling.

Bourinet E, Altier C, Hildebrand ME, Trang T, Salter MW, Zamponi GW.

Physiol Rev. 2014 Jan;94(1):81-140. doi: 10.1152/physrev.00023.2013. Review. Erratum in: Physiol Rev. 2014 Jul;94(3):987.

20.

Alleviating pain hypersensitivity through activation of type 4 metabotropic glutamate receptor.

Vilar B, Busserolles J, Ling B, Laffray S, Ulmann L, Malhaire F, Chapuy E, Aissouni Y, Etienne M, Bourinet E, Acher F, Pin JP, Eschalier A, Goudet C.

J Neurosci. 2013 Nov 27;33(48):18951-65. doi: 10.1523/JNEUROSCI.1221-13.2013.

21.

TAFA4, a chemokine-like protein, modulates injury-induced mechanical and chemical pain hypersensitivity in mice.

Delfini MC, Mantilleri A, Gaillard S, Hao J, Reynders A, Malapert P, Alonso S, François A, Barrere C, Seal R, Landry M, Eschallier A, Alloui A, Bourinet E, Delmas P, Le Feuvre Y, Moqrich A.

Cell Rep. 2013 Oct 31;5(2):378-88. doi: 10.1016/j.celrep.2013.09.013. Epub 2013 Oct 17.

22.

State-dependent properties of a new T-type calcium channel blocker enhance Ca(V)3.2 selectivity and support analgesic effects.

Francois A, Kerckhove N, Meleine M, Alloui A, Barrere C, Gelot A, Uebele VN, Renger JJ, Eschalier A, Ardid D, Bourinet E.

Pain. 2013 Feb;154(2):283-93. doi: 10.1016/j.pain.2012.10.023. Epub 2012 Nov 5.

PMID:
23257507
23.

AKAP79 modulation of L-type channels involves disruption of intramolecular interactions in the CaV1.2 subunit.

Altier C, Dubel SJ, Barrere C, Jarvis SE, Stotz SC, Scott JD, Nargeot J, Zamponi GW, Bourinet E.

Channels (Austin). 2012 May-Jun;6(3):157-65. doi: 10.4161/chan.20865. Epub 2012 May 1.

24.

T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome.

Marger F, Gelot A, Alloui A, Matricon J, Ferrer JF, Barrère C, Pizzoccaro A, Muller E, Nargeot J, Snutch TP, Eschalier A, Bourinet E, Ardid D.

Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11268-73. doi: 10.1073/pnas.1100869108. Epub 2011 Jun 20.

25.

Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors.

Descoeur J, Pereira V, Pizzoccaro A, Francois A, Ling B, Maffre V, Couette B, Busserolles J, Courteix C, Noel J, Lazdunski M, Eschalier A, Authier N, Bourinet E.

EMBO Mol Med. 2011 May;3(5):266-78. doi: 10.1002/emmm.201100134. Epub 2011 Mar 24.

26.

Heterodimerization of ORL1 and opioid receptors and its consequences for N-type calcium channel regulation.

Evans RM, You H, Hameed S, Altier C, Mezghrani A, Bourinet E, Zamponi GW.

J Biol Chem. 2010 Jan 8;285(2):1032-40. doi: 10.1074/jbc.M109.040634. Epub 2009 Nov 3.

27.

T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids.

Barbara G, Alloui A, Nargeot J, Lory P, Eschalier A, Bourinet E, Chemin J.

J Neurosci. 2009 Oct 21;29(42):13106-14. doi: 10.1523/JNEUROSCI.2919-09.2009.

28.

Animal models of chemotherapy-evoked painful peripheral neuropathies.

Authier N, Balayssac D, Marchand F, Ling B, Zangarelli A, Descoeur J, Coudore F, Bourinet E, Eschalier A.

Neurotherapeutics. 2009 Oct;6(4):620-9. doi: 10.1016/j.nurt.2009.07.003. Review.

29.

The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic beta-cell line.

Swayne LA, Mezghrani A, Varrault A, Chemin J, Bertrand G, Dalle S, Bourinet E, Lory P, Miller RJ, Nargeot J, Monteil A.

EMBO Rep. 2009 Aug;10(8):873-80. doi: 10.1038/embor.2009.125. Epub 2009 Jul 3.

30.

Stable membrane expression of postsynaptic CaV1.2 calcium channel clusters is independent of interactions with AKAP79/150 and PDZ proteins.

Di Biase V, Obermair GJ, Szabo Z, Altier C, Sanguesa J, Bourinet E, Flucher BE.

J Neurosci. 2008 Dec 17;28(51):13845-55. doi: 10.1523/JNEUROSCI.3213-08.2008.

31.

Assessing the chemical and biological diversity of an ion channels knowledge database.

Ijjaali I, Dubus E, Bourinet E, Petitet F.

Channels (Austin). 2007 Jul-Aug;1(4):291-9. Epub 2007 Sep 28.

PMID:
18708748
32.

Ligand-based virtual screening to identify new T-type calcium channel blockers.

Ijjaali I, Barrere C, Nargeot J, Petitet F, Bourinet E.

Channels (Austin). 2007 Jul-Aug;1(4):300-4. Epub 2007 Sep 7.

PMID:
18708747
33.

A destructive interaction mechanism accounts for dominant-negative effects of misfolded mutants of voltage-gated calcium channels.

Mezghrani A, Monteil A, Watschinger K, Sinnegger-Brauns MJ, Barrère C, Bourinet E, Nargeot J, Striessnig J, Lory P.

J Neurosci. 2008 Apr 23;28(17):4501-11. doi: 10.1523/JNEUROSCI.2844-07.2008.

34.

Voltage-gated calcium channels in chronic pain: emerging role of alternative splicing.

Swayne LA, Bourinet E.

Pflugers Arch. 2008 Jun;456(3):459-66. doi: 10.1007/s00424-007-0390-4. Epub 2008 Apr 4. Review.

PMID:
18389277
35.

ORL1 receptor-mediated internalization of N-type calcium channels.

Altier C, Khosravani H, Evans RM, Hameed S, Peloquin JB, Vartian BA, Chen L, Beedle AM, Ferguson SS, Mezghrani A, Dubel SJ, Bourinet E, McRory JE, Zamponi GW.

Nat Neurosci. 2006 Jan;9(1):31-40. Epub 2005 Nov 27.

PMID:
16311589
36.

Voltage gated calcium channels as targets for analgesics.

Bourinet E, Zamponi GW.

Curr Top Med Chem. 2005;5(6):539-46. Review.

PMID:
16022676
37.

Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes.

Mangoni ME, Couette B, Marger L, Bourinet E, Striessnig J, Nargeot J.

Prog Biophys Mol Biol. 2006 Jan-Apr;90(1-3):38-63. Epub 2005 Jun 6. Review.

PMID:
15979127
38.

Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception.

Bourinet E, Alloui A, Monteil A, Barrère C, Couette B, Poirot O, Pages A, McRory J, Snutch TP, Eschalier A, Nargeot J.

EMBO J. 2005 Jan 26;24(2):315-24. Epub 2004 Dec 16.

39.

Acetaminophen: a central analgesic drug that involves a spinal tropisetron-sensitive, non-5-HT(3) receptor-mediated effect.

Libert F, Bonnefont J, Bourinet E, Doucet E, Alloui A, Hamon M, Nargeot J, Eschalier A.

Mol Pharmacol. 2004 Sep;66(3):728-34.

PMID:
15322266
40.

Dissecting the functional role of different isoforms of the L-type Ca2+ channel.

Bourinet E, Mangoni ME, Nargeot J.

J Clin Invest. 2004 May;113(10):1382-4. Review.

41.

Plasma membrane expression of T-type calcium channel alpha(1) subunits is modulated by high voltage-activated auxiliary subunits.

Dubel SJ, Altier C, Chaumont S, Lory P, Bourinet E, Nargeot J.

J Biol Chem. 2004 Jul 9;279(28):29263-9. Epub 2004 Apr 27.

42.

Differential targeting of the L-type Ca2+ channel alpha 1C (CaV1.2) to synaptic and extrasynaptic compartments in hippocampal neurons.

Obermair GJ, Szabo Z, Bourinet E, Flucher BE.

Eur J Neurosci. 2004 Apr;19(8):2109-22.

PMID:
15090038
43.

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

Beedle AM, McRory JE, Poirot O, Doering CJ, Altier C, Barrere C, Hamid J, Nargeot J, Bourinet E, Zamponi GW.

Nat Neurosci. 2004 Feb;7(2):118-25. Epub 2004 Jan 18.

PMID:
14730309
44.

Functional role of L-type Cav1.3 Ca2+ channels in cardiac pacemaker activity.

Mangoni ME, Couette B, Bourinet E, Platzer J, Reimer D, Striessnig J, Nargeot J.

Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5543-8. Epub 2003 Apr 16.

45.

Multiple determinants in voltage-dependent P/Q calcium channels control their retention in the endoplasmic reticulum.

Cornet V, Bichet D, Sandoz G, Marty I, Brocard J, Bourinet E, Mori Y, Villaz M, De Waard M.

Eur J Neurosci. 2002 Sep;16(5):883-95.

PMID:
12372025
46.

Trafficking of L-type calcium channels mediated by the postsynaptic scaffolding protein AKAP79.

Altier C, Dubel SJ, Barrère C, Jarvis SE, Stotz SC, Spaetgens RL, Scott JD, Cornet V, De Waard M, Zamponi GW, Nargeot J, Bourinet E.

J Biol Chem. 2002 Sep 13;277(37):33598-603. Epub 2002 Jul 11.

47.

Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.

Chemin J, Monteil A, Perez-Reyes E, Bourinet E, Nargeot J, Lory P.

J Physiol. 2002 Apr 1;540(Pt 1):3-14.

48.

Interaction of SNX482 with domains III and IV inhibits activation gating of alpha(1E) (Ca(V)2.3) calcium channels.

Bourinet E, Stotz SC, Spaetgens RL, Dayanithi G, Lemos J, Nargeot J, Zamponi GW.

Biophys J. 2001 Jul;81(1):79-88.

49.

Multiple structural elements contribute to voltage-dependent facilitation of neuronal alpha 1C (CaV1.2) L-type calcium channels.

Altier C, Spaetgens RL, Nargeot J, Bourinet E, Zamponi GW.

Neuropharmacology. 2001 Jun;40(8):1050-7.

PMID:
11406197
50.

Supplemental Content

Loading ...
Support Center