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Items: 9


Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination.

Bourgo RJ, Singhal H, Greene GL.

Nat Commun. 2016 Sep 16;7:12893. doi: 10.1038/ncomms12893.


Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors in breast cancer.

Singhal H, Greene ME, Tarulli G, Zarnke AL, Bourgo RJ, Laine M, Chang YF, Ma S, Dembo AG, Raj GV, Hickey TE, Tilley WD, Greene GL.

Sci Adv. 2016 Jun 24;2(6):e1501924. doi: 10.1126/sciadv.1501924. eCollection 2016 Jun.


Retinoblastoma protein potentiates the innate immune response in hepatocytes: significance for hepatocellular carcinoma.

Hutcheson J, Bourgo RJ, Balaji U, Ertel A, Witkiewicz AK, Knudsen ES.

Hepatology. 2014 Oct;60(4):1231-40. doi: 10.1002/hep.27217. Epub 2014 Aug 28.


Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics.

Chapa J, Bourgo RJ, Greene GL, Kulkarni S, An G.

PLoS One. 2013 May 21;8(5):e64091. doi: 10.1371/journal.pone.0064091. Print 2013.


RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control.

Bourgo RJ, Thangavel C, Ertel A, Bergseid J, McClendon AK, Wilkens L, Witkiewicz AK, Wang JY, Knudsen ES.

Mol Cell. 2011 Aug 19;43(4):663-72. doi: 10.1016/j.molcel.2011.06.029.


RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage.

McClendon AK, Dean JL, Ertel A, Fu Z, Rivadeneira DB, Reed CA, Bourgo RJ, Witkiewicz A, Addya S, Mayhew CN, Grimes HL, Fortina P, Knudsen ES.

Gastroenterology. 2011 Oct;141(4):1439-50. doi: 10.1053/j.gastro.2011.06.046. Epub 2011 Jun 24.


RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo.

Bourgo RJ, Ehmer U, Sage J, Knudsen ES.

Mol Biol Cell. 2011 Apr;22(7):931-9. doi: 10.1091/mbc.E10-11-0895. Epub 2011 Feb 2.


SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.

Bourgo RJ, Siddiqui H, Fox S, Solomon D, Sansam CG, Yaniv M, Muchardt C, Metzger D, Chambon P, Roberts CW, Knudsen ES.

Mol Biol Cell. 2009 Jul;20(14):3192-9. doi: 10.1091/mbc.E08-12-1224. Epub 2009 May 20.


Activation of the retinoblastoma tumor suppressor mediates cell cycle inhibition and cell death in specific cervical cancer cell lines.

Bourgo RJ, Braden WA, Wells SI, Knudsen ES.

Mol Carcinog. 2009 Jan;48(1):45-55. doi: 10.1002/mc.20456.

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