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Items: 23


Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy.

Bertero T, Oldham WM, Grasset EM, Bourget I, Boulter E, Pisano S, Hofman P, Bellvert F, Meneguzzi G, Bulavin DV, Estrach S, Feral CC, Chan SY, Bozec A, Gaggioli C.

Cell Metab. 2019 Jan 8;29(1):124-140.e10. doi: 10.1016/j.cmet.2018.09.012. Epub 2018 Oct 4.


Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells.

Grasset EM, Bertero T, Bozec A, Friard J, Bourget I, Pisano S, Lecacheur M, Maiel M, Bailleux C, Emelyanov A, Ilie M, Hofman P, Meneguzzi G, Duranton C, Bulavin DV, Gaggioli C.

Cancer Res. 2018 Sep 15;78(18):5229-5242. doi: 10.1158/0008-5472.CAN-18-0601. Epub 2018 Jul 19.


A new long noncoding RNA (lncRNA) is induced in cutaneous squamous cell carcinoma and down-regulates several anticancer and cell differentiation genes in mouse.

Ponzio G, Rezzonico R, Bourget I, Allan R, Nottet N, Popa A, Magnone V, Rios G, Mari B, Barbry P.

J Biol Chem. 2017 Jul 28;292(30):12483-12495. doi: 10.1074/jbc.M117.776260. Epub 2017 Jun 8.


Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts.

Bonan S, Albrengues J, Grasset E, Kuzet SE, Nottet N, Bourget I, Bertero T, Mari B, Meneguzzi G, Gaggioli C.

Oncotarget. 2017 Jan 3;8(1):1304-1320. doi: 10.18632/oncotarget.13610.


Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts.

Albrengues J, Bertero T, Grasset E, Bonan S, Maiel M, Bourget I, Philippe C, Herraiz Serrano C, Benamar S, Croce O, Sanz-Moreno V, Meneguzzi G, Feral CC, Cristofari G, Gaggioli C.

Nat Commun. 2015 Dec 15;6:10204. doi: 10.1038/ncomms10204.


Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation.

Brahimi-Horn MC, Giuliano S, Saland E, Lacas-Gervais S, Sheiko T, Pelletier J, Bourget I, Bost F, Féral C, Boulter E, Tauc M, Ivan M, Garmy-Susini B, Popa A, Mari B, Sarry JE, Craigen WJ, Pouysségur J, Mazure NM.

Cancer Metab. 2015 Aug 26;3:8. doi: 10.1186/s40170-015-0133-5. eCollection 2015.


LIF mediates proinvasive activation of stromal fibroblasts in cancer.

Albrengues J, Bourget I, Pons C, Butet V, Hofman P, Tartare-Deckert S, Feral CC, Meneguzzi G, Gaggioli C.

Cell Rep. 2014 Jun 12;7(5):1664-1678. doi: 10.1016/j.celrep.2014.04.036. Epub 2014 May 22.


HIF1 transcription factor regulates laminin-332 expression and keratinocyte migration.

Fitsialos G, Bourget I, Augier S, Ginouvès A, Rezzonico R, Odorisio T, Cianfarani F, Virolle T, Pouysségur J, Meneguzzi G, Berra E, Ponzio G, Buscà R.

J Cell Sci. 2008 Sep 15;121(Pt 18):2992-3001. doi: 10.1242/jcs.029256. Epub 2008 Aug 19.


Diagnostic challenges in facioscapulohumeral muscular dystrophy.

Sacconi S, Salviati L, Bourget I, Figarella D, Péréon Y, Lemmers R, van der Maarel S, Desnuelle C.

Neurology. 2006 Oct 24;67(8):1464-6.


hCOX18 and hCOX19: two human genes involved in cytochrome c oxidase assembly.

Sacconi S, Trevisson E, Pistollato F, Baldoin MC, Rezzonico R, Bourget I, Desnuelle C, Tenconi R, Basso G, DiMauro S, Salviati L.

Biochem Biophys Res Commun. 2005 Nov 25;337(3):832-9. Epub 2005 Sep 29.


Dominant negative effect of connexin33 on gap junctional communication is mediated by connexin43 sequestration.

Fiorini C, Mograbi B, Cronier L, Bourget I, Decrouy X, Nebout M, Ferrua B, Malassine A, Samson M, Fénichel P, Segretain D, Pointis G.

J Cell Sci. 2004 Sep 15;117(Pt 20):4665-72. Epub 2004 Aug 25.


Down-regulation of Hox A7 is required for cell adhesion and migration on fibronectin during early HL-60 monocytic differentiation.

Leroy P, Berto F, Bourget I, Rossi B.

J Leukoc Biol. 2004 Apr;75(4):680-8. Epub 2004 Jan 2.


Cross-talk between RhoGTPases and stress activated kinases for matrix metalloproteinase-9 induction in response to keratinocytes injury.

Turchi L, Chassot AA, Bourget I, Baldescchi C, Ortonne JP, Meneguzzi G, Lemichez E, Ponzio G.

J Invest Dermatol. 2003 Dec;121(6):1291-300.


The sensitivity of activated Cys Ret mutants to glial cell line-derived neurotrophic factor is mandatory to rescue neuroectodermic cells from apoptosis.

Mograbi B, Bocciardi R, Bourget I, Juhel T, Farahi-Far D, Romeo G, Ceccherini I, Rossi B.

Mol Cell Biol. 2001 Oct;21(20):6719-30.


Glial cell line-derived neurotrophic factor-stimulated phosphatidylinositol 3-kinase and Akt activities exert opposing effects on the ERK pathway: importance for the rescue of neuroectodermic cells.

Mograbi B, Bocciardi R, Bourget I, Busca R, Rochet N, Farahi-Far D, Juhel T, Rossi B.

J Biol Chem. 2001 Nov 30;276(48):45307-19. Epub 2001 Sep 4.


The multiple endocrine neoplasia type 2B point mutation switches the specificity of the Ret tyrosine kinase towards cellular substrates that are susceptible to interact with Crk and Nck.

Bocciardi R, Mograbi B, Pasini B, Borrello MG, Pierotti MA, Bourget I, Fischer S, Romeo G, Rossi B.

Oncogene. 1997 Nov 6;15(19):2257-65.


Human monocytes express amphiregulin and heregulin growth factors upon activation.

Mograbi B, Rochet N, Imbert V, Bourget I, Bocciardi R, Emiliozzi C, Rossi B.

Eur Cytokine Netw. 1997 Mar;8(1):73-81.


CD20 monoclonal antibodies decrease interleukin-4-stimulated expression of the low-affinity receptor for IgE (Fc epsilon RII/CD23) in human B cells by increasing the extent of its cleavage.

Bourget I, Di Berardino W, Breittmayer JP, Grenier-Brossette N, Plana-Prades M, Bonnefoy JY, Cousin JL.

Eur J Immunol. 1995 Jul;25(7):1872-6.


CD20 monoclonal antibodies stimulate extracellular cleavage of the low affinity receptor for IgE (Fc epsilon RII/CD23) in Epstein-Barr-transformed B cells.

Bourget I, Di Berardino W, Breittmayer JP, Grenier-Brossette N, Plana-Prades M, Bonnefoy JY, Cousin JL.

J Biol Chem. 1994 Mar 4;269(9):6927-30.


Platelet-activating factor activates a Ca(2+)-dependent K+ channel which is not involved in c-fos expression in human B lymphoblastoid cells.

Di Berardino W, Bourget I, Schmid-Antomarchi H, Cousin JL.

Cell Signal. 1993 Sep;5(5):623-31.


CD20 monoclonal antibodies down-regulate IgM at the surface of B cells.

Bourget I, Breittmayer JP, Grenier-Brossette N, Cousin JL.

Eur J Immunol. 1993 Mar;23(3):768-71.


Spontaneous and ligand-induced endocytosis of CD23 (Fc epsilon receptor II) from the surface of B lymphocytes generates a 16-kDa intracellular fragment.

Grenier-Brossette N, Bourget I, Akoundi C, Bonnefoy JY, Cousin JL.

Eur J Immunol. 1992 Jun;22(6):1573-7.


Pertussis toxin-induced mitogenesis in human T lymphocytes.

Grenier-Brossette N, Bourget I, Breittmayer JP, Ferrua B, Fehlmann M, Cousin JL.

Immunopharmacology. 1991 Mar-Apr;21(2):109-19.


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