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Items: 24

1.

ROS-mediated EB1 phosphorylation through Akt/GSK3β pathway: implication in cancer cell response to microtubule-targeting agents.

Le Grand M, Rovini A, Bourgarel-Rey V, Honore S, Bastonero S, Braguer D, Carre M.

Oncotarget. 2014 May 30;5(10):3408-23.

2.

Bcl-2-enhanced efficacy of microtubule-targeting chemotherapy through Bim overexpression: implications for cancer treatment.

Savry A, Carre M, Berges R, Rovini A, Pobel I, Chacon C, Braguer D, Bourgarel-Rey V.

Neoplasia. 2013 Jan;15(1):49-60.

3.

Impact of plasma and intracellular exposure and CYP3A4, CYP3A5, and ABCB1 genetic polymorphisms on vincristine-induced neurotoxicity.

Guilhaumou R, Solas C, Bourgarel-Rey V, Quaranta S, Rome A, Simon N, Lacarelle B, Andre N.

Cancer Chemother Pharmacol. 2011 Dec;68(6):1633-8. doi: 10.1007/s00280-011-1745-2. Epub 2011 Oct 4.

PMID:
21968951
4.

Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins. Part 2.

Combes S, Barbier P, Douillard S, McLeer-Florin A, Bourgarel-Rey V, Pierson JT, Fedorov AY, Finet JP, Boutonnat J, Peyrot V.

J Med Chem. 2011 May 12;54(9):3153-62. doi: 10.1021/jm901826e. Epub 2011 Apr 13.

PMID:
21488686
5.

Transcriptional down-regulation of Bcl-2 by vinorelbine: identification of a novel binding site of p53 on Bcl-2 promoter.

Bourgarel-Rey V, Savry A, Hua G, Carré M, Bressin C, Chacon C, Imbert J, Braguer D, Barra Y.

Biochem Pharmacol. 2009 Nov 1;78(9):1148-56. doi: 10.1016/j.bcp.2009.06.025. Epub 2009 Jun 23.

PMID:
19555669
6.

Synthesis and biological evaluation of polymethoxylated 4-heteroarylcoumarins as tubulin assembly inhibitor.

Ganina OG, Daras E, Bourgarel-Rey V, Peyrot V, Andresyuk AN, Finet JP, Fedorov AY, Beletskaya IP, Combes S.

Bioorg Med Chem. 2008 Oct 1;16(19):8806-12. doi: 10.1016/j.bmc.2008.09.003. Epub 2008 Sep 5.

PMID:
18805012
7.

Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites.

Honoré S, Pagano A, Gauthier G, Bourgarel-Rey V, Verdier-Pinard P, Civiletti K, Kruczynski A, Braguer D.

Mol Cancer Ther. 2008 Jul;7(7):2080-9. doi: 10.1158/1535-7163.MCT-08-0156.

8.

Nox1 downstream of 12-lipoxygenase controls cell proliferation but not cell spreading of colon cancer cells.

de Carvalho DD, Sadok A, Bourgarel-Rey V, Gattacceca F, Penel C, Lehmann M, Kovacic H.

Int J Cancer. 2008 Apr 15;122(8):1757-64.

9.

Nox1-dependent superoxide production controls colon adenocarcinoma cell migration.

Sadok A, Bourgarel-Rey V, Gattacceca F, Penel C, Lehmann M, Kovacic H.

Biochim Biophys Acta. 2008 Jan;1783(1):23-33. Epub 2007 Oct 30.

10.

Minimal effect of MDR1 and CYP3A5 genetic polymorphisms on the pharmacokinetics of indinavir in HIV-infected patients.

Solas C, Simon N, Drogoul MP, Quaranta S, Frixon-Marin V, Bourgarel-Rey V, Brunet C, Gastaut JA, Durand A, Lacarelle B, Poizot-Martin I.

Br J Clin Pharmacol. 2007 Sep;64(3):353-62. Epub 2007 May 22.

11.

Cascade synthesis of polyoxygenated 6H,11H-[2]benzopyrano-[4,3-c][1]benzopyran-11-ones.

Naumov MI, Sutirin SA, Shavyrin AS, Ganina OG, Beletskaya IP, Bourgarel-Rey V, Combes S, Finet JP, Fedorov AY.

J Org Chem. 2007 Apr 27;72(9):3293-301. Epub 2007 Mar 28.

PMID:
17388631
12.

Bcl-2 down-regulation and tubulin subtype composition are involved in resistance of ovarian cancer cells to vinflunine.

Estève MA, Carré M, Bourgarel-Rey V, Kruczynski A, Raspaglio G, Ferlini C, Braguer D.

Mol Cancer Ther. 2006 Nov;5(11):2824-33.

13.

Interaction of 4-arylcoumarin analogues of combretastatins with microtubule network of HBL100 cells and binding to tubulin.

Rappl C, Barbier P, Bourgarel-Rey V, Grégoire C, Gilli R, Carre M, Combes S, Finet JP, Peyrot V.

Biochemistry. 2006 Aug 1;45(30):9210-8.

PMID:
16866367
14.

Caulerpenyne-colchicine hybrid: synthesis and biological evaluation.

Bourdron J, Commeiras L, Barbier P, Bourgarel-Rey V, Pasquier E, Vanthuyne N, Hubaud JC, Peyrot V, Parrain JL.

Bioorg Med Chem. 2006 Aug 15;14(16):5540-8. Epub 2006 May 22.

PMID:
16714115
15.

Antiangiogenic concentrations of vinflunine increase the interphase microtubule dynamics and decrease the motility of endothelial cells.

Pourroy B, Honoré S, Pasquier E, Bourgarel-Rey V, Kruczynski A, Briand C, Braguer D.

Cancer Res. 2006 Mar 15;66(6):3256-63.

16.

Identification by single-strand conformational polymorphism analysis of known and new mutations of the CYP3A5 gene in a French population.

Quaranta S, Chevalier D, Bourgarel-Rey V, Allorge D, Solas C, Lo-Guidice JM, Sampol-Manos E, Vacher-Coponat H, Moal V, Broly F, Lhermitte M, Lacarelle B.

Toxicol Lett. 2006 Jul 1;164(2):177-84. Epub 2006 Jan 25.

PMID:
16442753
17.

Decrease in c-Myc activity enhances cancer cell sensitivity to vinblastine.

Bressin C, Bourgarel-Rey V, Carré M, Pourroy B, Arango D, Braguer D, Barra Y.

Anticancer Drugs. 2006 Feb;17(2):181-7.

PMID:
16428936
18.

The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis.

Campbell GR, Pasquier E, Watkins J, Bourgarel-Rey V, Peyrot V, Esquieu D, Barbier P, de Mareuil J, Braguer D, Kaleebu P, Yirrell DL, Loret EP.

J Biol Chem. 2004 Nov 12;279(46):48197-204. Epub 2004 Aug 24.

19.

Retinoids repress Ah receptor CYP1A1 induction pathway through the SMRT corepressor.

Fallone F, Villard PH, Sérée E, Rimet O, Nguyen QB, Bourgarel-Rey V, Fouchier F, Barra Y, Durand A, Lacarelle B.

Biochem Biophys Res Commun. 2004 Sep 17;322(2):551-6.

20.

Low concentrations of vinflunine induce apoptosis in human SK-N-SH neuroblastoma cells through a postmitotic G1 arrest and a mitochondrial pathway.

Pourroy B, Carré M, Honoré S, Bourgarel-Rey V, Kruczynski A, Briand C, Braguer D.

Mol Pharmacol. 2004 Sep;66(3):580-91.

PMID:
15322250
21.

Involvement of nuclear factor kappaB in c-Myc induction by tubulin polymerization inhibitors.

Bourgarel-Rey V, Vallee S, Rimet O, Champion S, Braguer D, Desobry A, Briand C, Barra Y.

Mol Pharmacol. 2001 May;59(5):1165-70.

PMID:
11306700
22.

Opposite effects of antimicrotubule agents on c-myc oncogene expression depending on the cell lines used.

Bourgarel-Rey V, El Khyari S, Rimet O, Bordas B, Guigal N, Braguer D, Seree E, Barra Y, Briand C.

Eur J Cancer. 2000 May;36(8):1043-9.

PMID:
10885610
23.

Induction of CYP1A1 by serum independent of AhR pathway.

Guigal N, Seree E, Bourgarel-Rey V, Barra Y.

Biochem Biophys Res Commun. 2000 Jan 19;267(2):572-6.

PMID:
10631103
24.

Metabolism of carbamazepine by CYP3A6: a model for in vitro drug interactions studies.

Mesdjian E, Sérée E, Charvet B, Mirrione A, Bourgarel-Rey V, Desobry A, Barra Y.

Life Sci. 1999;64(10):827-35.

PMID:
10096433

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