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Items: 1 to 50 of 59

1.

Drug discovery in the new millennium: the pivotal role of biotechnology.

Boulnois GJ.

Trends Biotechnol. 2000 Jan;18(1):31-3.

PMID:
10631779
2.

Streptococcus pneumoniae produces a second haemolysin that is distinct from pneumolysin.

Canvin JR, Paton JC, Boulnois GJ, Andrew PW, Mitchell TJ.

Microb Pathog. 1997 Mar;22(3):129-32.

PMID:
9075215
3.

The role of pneumolysin and autolysin in the pathology of pneumonia and septicemia in mice infected with a type 2 pneumococcus.

Canvin JR, Marvin AP, Sivakumaran M, Paton JC, Boulnois GJ, Andrew PW, Mitchell TJ.

J Infect Dis. 1995 Jul;172(1):119-23.

PMID:
7797901
4.

Growth and virulence of a complement-activation-negative mutant of Streptococcus pneumoniae in the rabbit cornea.

Johnson MK, Callegan MC, Engel LS, O'Callaghan RJ, Hill JM, Hobden JA, Boulnois GJ, Andrew PW, Mitchell TJ.

Curr Eye Res. 1995 Apr;14(4):281-4.

PMID:
7606914
5.

A neuraminidase from Streptococcus pneumoniae has the features of a surface protein.

Cámara M, Boulnois GJ, Andrew PW, Mitchell TJ.

Infect Immun. 1994 Sep;62(9):3688-95.

6.

A role in cell-binding for the C-terminus of pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae.

Owen RH, Boulnois GJ, Andrew PW, Mitchell TJ.

FEMS Microbiol Lett. 1994 Aug 15;121(2):217-21.

PMID:
7926673
7.
8.
9.
11.

Genetic analysis of the gene cluster encoding nonfimbrial adhesin I from an Escherichia coli uropathogen.

Ahrens R, Ott M, Ritter A, Hoschützky H, Bühler T, Lottspeich F, Boulnois GJ, Jann K, Hacker J.

Infect Immun. 1993 Jun;61(6):2505-12.

12.

Cytotoxic effects on hair cells of guinea pig cochlea produced by pneumolysin, the thiol activated toxin of Streptococcus pneumoniae.

Comis SD, Osborne MP, Stephen J, Tarlow MJ, Hayward TL, Mitchell TJ, Andrew PW, Boulnois GJ.

Acta Otolaryngol. 1993 Mar;113(2):152-9.

PMID:
8475728
13.

Molecular and cell biology of opportunistic infections in AIDS. Mycobacteria.

Ralphs NT, Boulnois GJ, Andrew PW.

Mol Cell Biol Hum Dis Ser. 1993;2:71-93. Review. No abstract available.

PMID:
8261180
14.

Molecular analysis of the pathogenicity of Streptococcus pneumoniae: the role of pneumococcal proteins.

Paton JC, Andrew PW, Boulnois GJ, Mitchell TJ.

Annu Rev Microbiol. 1993;47:89-115. Review.

PMID:
7903033
15.

Effect of immunization with Freund's adjuvant and pneumolysin on histologic features of pneumococcal infection in the rat lung in vivo.

Roberts P, Jeffery PK, Mitchell TJ, Andrew PW, Boulnois GJ, Feldman C, Cole PJ, Wilson R.

Infect Immun. 1992 Nov;60(11):4969-72.

16.

The interaction of Streptococcus pneumoniae with intact human respiratory mucosa in vitro.

Feldman C, Read R, Rutman A, Jeffery PK, Brain A, Lund V, Mitchell TJ, Andrew PW, Boulnois GJ, Todd HC, et al.

Eur Respir J. 1992 May;5(5):576-83.

PMID:
1612157
17.

Pneumococcal proteins and the pathogenesis of disease caused by Streptococcus pneumoniae.

Boulnois GJ.

J Gen Microbiol. 1992 Feb;138(2):249-59. Review. No abstract available.

PMID:
1564436
18.

Pneumolysin induces the salient histologic features of pneumococcal infection in the rat lung in vivo.

Feldman C, Munro NC, Jeffery PK, Mitchell TJ, Andrew PW, Boulnois GJ, Guerreiro D, Rohde JA, Todd HC, Cole PJ, et al.

Am J Respir Cell Mol Biol. 1991 Nov;5(5):416-23.

PMID:
1834101
19.

Structure and function of pneumolysin, the multifunctional, thiol-activated toxin of Streptococcus pneumoniae.

Boulnois GJ, Paton JC, Mitchell TJ, Andrew PW.

Mol Microbiol. 1991 Nov;5(11):2611-6. Review.

PMID:
1779752
21.

Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein.

Mitchell TJ, Andrew PW, Saunders FK, Smith AN, Boulnois GJ.

Mol Microbiol. 1991 Aug;5(8):1883-8.

PMID:
1766369
22.

Purification and immunogenicity of genetically obtained pneumolysin toxoids and their conjugation to Streptococcus pneumoniae type 19F polysaccharide.

Paton JC, Lock RA, Lee CJ, Li JP, Berry AM, Mitchell TJ, Andrew PW, Hansman D, Boulnois GJ.

Infect Immun. 1991 Jul;59(7):2297-304.

23.

A DNA primer/probe system for the rapid and sensitive detection of Mycobacterium tuberculosis-complex pathogens.

Ralphs NT, Garrett S, Morse R, Cookson JB, Andrew PW, Boulnois GJ.

J Appl Bacteriol. 1991 Mar;70(3):221-6.

PMID:
1903132
24.

Sequence of the Candida albicans gene encoding the secretory aspartate proteinase.

Hube B, Turver CJ, Odds FC, Eiffert H, Boulnois GJ, Köchel H, Rüchel R.

J Med Vet Mycol. 1991;29(2):129-32.

PMID:
1880680
25.

[Identification, cloning and characterization of the gene for the secretory aspartate protease of Candida albicans].

Hube B, Turver CJ, Odds FC, Eiffert H, Boulnois GJ, Köchel H, Rüchel R.

Mycoses. 1991;34 Suppl 1:59-61. German. No abstract available.

PMID:
1818265
27.

The effect of Streptococcus pneumoniae pneumolysin on human respiratory epithelium in vitro.

Feldman C, Mitchell TJ, Andrew PW, Boulnois GJ, Read RC, Todd HC, Cole PJ, Wilson R.

Microb Pathog. 1990 Oct;9(4):275-84.

PMID:
2097494
28.

Comparison of pneumolysin genes and proteins from Streptococcus pneumoniae types 1 and 2.

Mitchell TJ, Mendez F, Paton JC, Andrew PW, Boulnois GJ.

Nucleic Acids Res. 1990 Jul 11;18(13):4010. No abstract available.

29.

Identification and characterization of a gene that controls colony morphology and auto-aggregation in Escherichia coli K12.

Warne SR, Varley JM, Boulnois GJ, Norton MG.

J Gen Microbiol. 1990 Mar;136(3):455-62.

PMID:
2167922
30.

Molecular cloning and expression of the genes encoding the Escherichia coli K4 capsular polysaccharide, a fructose-substituted chondroitin.

Drake CR, Roberts IS, Jann B, Jann K, Boulnois GJ.

FEMS Microbiol Lett. 1990 Jan 1;54(1-3):227-30.

PMID:
2182375
31.

Genetics of capsular polysaccharide production in bacteria.

Boulnois GJ, Roberts IS.

Curr Top Microbiol Immunol. 1990;150:1-18. Review. No abstract available.

PMID:
2105187
32.

Bacterial polysaccharide capsule synthesis, export and evolution of structural diversity.

Boulnois GJ, Jann K.

Mol Microbiol. 1989 Dec;3(12):1819-23. Review.

PMID:
2695750
33.

Pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae, does not require a thiol group for in vitro activity.

Saunders FK, Mitchell TJ, Walker JA, Andrew PW, Boulnois GJ.

Infect Immun. 1989 Aug;57(8):2547-52.

34.

Bacterial capsules and interactions with complement and phagocytes.

Roberts IS, Saunders FK, Boulnois GJ.

Biochem Soc Trans. 1989 Jun;17(3):462-4. No abstract available.

PMID:
2666197
35.

Expression of the pneumolysin gene in Escherichia coli: rapid purification and biological properties.

Mitchell TJ, Walker JA, Saunders FK, Andrew PW, Boulnois GJ.

Biochim Biophys Acta. 1989 Jan 23;1007(1):67-72.

PMID:
2642385
36.

Genetics of capsular polysaccharide production in bacteria.

Boulnois GJ.

Symp Soc Exp Biol. 1989;43:417-22. Review.

PMID:
2701488
37.

Molecular cloning and characterisation of the genes for a non-fimbrial adhesin from Escherichia coli.

Hales BA, Beverley-Clarke H, High NJ, Jann K, Perry R, Goldhar J, Boulnois GJ.

Microb Pathog. 1988 Jul;5(1):9-17.

PMID:
2907599
38.

Common organization of gene clusters for production of different capsular polysaccharides (K antigens) in Escherichia coli.

Roberts IS, Mountford R, Hodge R, Jann KB, Boulnois GJ.

J Bacteriol. 1988 Mar;170(3):1305-10.

39.

DNA probes for K-antigen (capsule) typing of Escherichia coli.

Roberts M, Roberts I, Korhonen TK, Jann K, Bitter-Suermann D, Boulnois GJ, Williams PH.

J Clin Microbiol. 1988 Feb;26(2):385-7.

40.

A block of urovirulence genes encoding multiple fimbriae and hemolysin in Escherichia coli O4:K12:H-.

High NJ, Hales BA, Jann K, Boulnois GJ.

Infect Immun. 1988 Feb;56(2):513-7.

41.
42.

Contribution of capsular polysaccharide and surface properties to virulence of Escherichia coli K1.

Allen PM, Roberts I, Boulnois GJ, Saunders JR, Hart CA.

Infect Immun. 1987 Nov;55(11):2662-8.

43.

Analysis of the K1 capsule biosynthesis genes of Escherichia coli: definition of three functional regions for capsule production.

Boulnois GJ, Roberts IS, Hodge R, Hardy KR, Jann KB, Timmis KN.

Mol Gen Genet. 1987 Jun;208(1-2):242-6.

PMID:
3302608
44.
45.

Serotyping and genotyping of encapsulated Escherichia coli K1 sepsis isolates with a monoclonal IgG anti K1 antibody and K1 gene probes.

Frosch M, Roberts I, Görgen I, Metzger S, Boulnois GJ, Bitter-Suermann D.

Microb Pathog. 1987 May;2(5):319-26.

PMID:
3333802
47.

Surface components of Escherichia coli that mediate resistance to the bactericidal activities of serum and phagocytes.

Timmis KN, Boulnois GJ, Bitter-Suermann D, Cabello FC.

Curr Top Microbiol Immunol. 1985;118:197-218. Review. No abstract available.

PMID:
3902381
48.

Transposon donor plasmids, based on ColIb-P9, for use in Pseudomonas putida and a variety of other gram negative bacteria.

Boulnois GJ, Varley JM, Sharpe GS, Franklin FC.

Mol Gen Genet. 1985;200(1):65-7.

PMID:
2993815
49.
50.

Cloning and analysis of the K1 capsule biosynthesis genes of Escherichia coli: lack of homology with Neisseria meningitidis group B DNA sequences.

Echarti C, Hirschel B, Boulnois GJ, Varley JM, Waldvogel F, Timmis KN.

Infect Immun. 1983 Jul;41(1):54-60.

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