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Inhaled Corticosteroids and Adult Asthma.

Boulet LP, Nair P.

Am J Respir Crit Care Med. 2019 Jul 24. doi: 10.1164/rccm.201907-1301LE. [Epub ahead of print] No abstract available.


The Global Initiative for Asthma (GINA): 25 years later.

Boulet LP, Reddel H, Bateman E, Pedersen S, FitzGerald JM, O'Byrne PM.

Eur Respir J. 2019 Jul 4. pii: 1900598. doi: 10.1183/13993003.00598-2019. [Epub ahead of print] Review.


GINA 2019: a fundamental change in asthma management: Treatment of asthma with short-acting bronchodilators alone is no longer recommended for adults and adolescents.

Reddel HK, FitzGerald JM, Bateman ED, Bacharier LB, Becker A, Brusselle G, Buhl R, Cruz AA, Fleming L, Inoue H, Ko FW, Krishnan JA, Levy ML, Lin J, Pedersen SE, Sheikh A, Yorgancioglu A, Boulet LP.

Eur Respir J. 2019 Jun 27;53(6). pii: 1901046. doi: 10.1183/13993003.01046-2019. Print 2019 Jun. No abstract available.


Omalizumab in patients with severe asthma and persistent sputum eosinophilia.

Mukherjee M, Kjarsgaard M, Radford K, Huang C, Leigh R, Dorscheid DR, Lemiere C, Boulet LP, Waserman S, Martin J, Nair P.

Allergy Asthma Clin Immunol. 2019 Apr 3;15:21. doi: 10.1186/s13223-019-0337-2. eCollection 2019.


Impact of adding a video to patient education on quality of life among adults with atrial fibrillation: a randomized controlled trial.

Gagné M, Legault C, Boulet LP, Charbonneau L, Lemyre M, Giguere AMC, Poirier P.

Patient Educ Couns. 2019 Aug;102(8):1490-1498. doi: 10.1016/j.pec.2019.03.015. Epub 2019 Mar 31.


Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma.

Bousquet J, Bedbrook A, Czarlewski W, Onorato GL, Arnavielhe S, Laune D, Mathieu-Dupas E, Fonseca J, Costa E, Lourenço O, Morais-Almeida M, Todo-Bom A, Illario M, Menditto E, Canonica GW, Cecchi L, Monti R, Napoli L, Ventura MT, De Feo G, Fokkens WJ, Chavannes NH, Reitsma S, Cruz AA, da Silva J, Serpa FS, Larenas-Linnemann D, Fuentes Perez JM, Huerta-Villalobos YR, Rivero-Yeverino D, Rodriguez-Zagal E, Valiulis A, Dubakiene R, Emuzyte R, Kvedariene V, Annesi-Maesano I, Blain H, Bonniaud P, Bosse I, Dauvilliers Y, Devillier P, Fontaine JF, Pépin JL, Pham-Thi N, Portejoie F, Picard R, Roche N, Rolland C, Schmidt-Grendelmeier P, Kuna P, Samolinski B, Anto JM, Cardona V, Mullol J, Pinnock H, Ryan D, Sheikh A, Walker S, Williams S, Becker S, Klimek L, Pfaar O, Bergmann KC, Mösges R, Zuberbier T, Roller-Wirnsberger RE, Tomazic PV, Haahtela T, Salimäki J, Toppila-Salmi S, Valovirta E, Vasankari T, Gemicioğlu B, Yorgancioglu A, Papadopoulos NG, Prokopakis EP, Tsiligianni IG, Bosnic-Anticevich S, O'Hehir R, Ivancevich JC, Neffen H, Zernotti ME, Kull I, Melén E, Wickman M, Bachert C, Hellings PW, Brusselle G, Palkonen S, Bindslev-Jensen C, Eller E, Waserman S, Boulet LP, Bouchard J, Chu DK, Schünemann HJ, Sova M, De Vries G, van Eerd M, Agache I, Ansotegui IJ, Bewick M, Casale T, Dykewick M, Ebisawa M, Murray R, Naclerio R, Okamoto Y, Wallace DV; The MASK study group.

Clin Transl Allergy. 2019 Mar 11;9:16. doi: 10.1186/s13601-019-0252-0. eCollection 2019. Review.


Family medicine physician teachers and residents' intentions to prescribe and interpret spirometry: a descriptive cross-sectional study.

Desjardins A, Boulay MÈ, Gagné M, Simon M, Boulet LP.

J Asthma. 2019 Mar 23:1-11. doi: 10.1080/02770903.2018.1553052. [Epub ahead of print]


Longitudinal comparison of outcomes in patients with smoking-related asthma-COPD overlap and in non-smoking asthmatics with incomplete reversibility of airway obstruction.

Boulet LP, Boulay ME, Milot J, Lepage J, Bilodeau L, Maltais F.

Int J Chron Obstruct Pulmon Dis. 2019 Feb 27;14:493-498. doi: 10.2147/COPD.S192003. eCollection 2019.


Cough in exercise and athletes.

Boulet LP, Turmel J.

Pulm Pharmacol Ther. 2019 Apr;55:67-74. doi: 10.1016/j.pupt.2019.02.003. Epub 2019 Feb 13. Review.


The Electronic Asthma Management System (eAMS) improves primary care asthma management.

Gupta S, Price C, Agarwal G, Chan D, Goel S, Boulet LP, Kaplan AG, Lebovic G, Mamdani M, Straus SE.

Eur Respir J. 2019 Apr 25;53(4). pii: 1802241. doi: 10.1183/13993003.02241-2018. Print 2019 Apr.


Nouvel outil factuel pour orienter la création de plans d’action pour l’asthme chez les adultes.

Kouri A, Kaplan A, Boulet LP, Gupta S.

Can Fam Physician. 2019 Feb;65(2):e51-e55. Review. French.

Free PMC Article

New evidence-based tool to guide the creation of asthma action plans for adults.

Kouri A, Kaplan A, Boulet LP, Gupta S.

Can Fam Physician. 2019 Feb;65(2):103-106. Review.


Large care gaps in primary care management of asthma: a longitudinal practice audit.

Price C, Agarwal G, Chan D, Goel S, Kaplan AG, Boulet LP, Mamdani MM, Straus SE, Lebovic G, Gupta S.

BMJ Open. 2019 Jan 29;9(1):e022506. doi: 10.1136/bmjopen-2018-022506.


Development process and patient usability preferences for a touch screen tablet-based questionnaire.

Lam Shin Cheung V, Kastner M, Sale JE, Straus S, Kaplan A, Boulet LP, Gupta S.

Health Informatics J. 2019 Jan 23:1460458218824749. doi: 10.1177/1460458218824749. [Epub ahead of print]


Adherence stages measured by patient-reported outcome instruments in adults with asthma: a scoping review.

Gagné M, Boulet LP, Pérez N, Moisan J.

J Asthma. 2019 Jan 21:1-9. doi: 10.1080/02770903.2019.1565823. [Epub ahead of print]


Persistent Reduction of Mucin Production after Bronchial Thermoplasty in Severe Asthma.

Haj Salem I, Gras D, Joubert P, Boulet LP, Lampron N, Martel S, Godbout K, Chanez P, Laviolette M, Chakir J.

Am J Respir Crit Care Med. 2019 Feb 15;199(4):536-538. doi: 10.1164/rccm.201811-2064LE. No abstract available.


The many faces of asthma-chronic obstructive pulmonary disease overlap.

Boulet LP, Hanania NA.

Curr Opin Pulm Med. 2019 Jan;25(1):1-10. doi: 10.1097/MCP.0000000000000547.


Changes in airway inflammation and remodelling in swimmers after quitting sport competition.

Bougault V, Odashiro P, Turmel J, Orain M, Laviolette M, Joubert P, Boulet LP.

Clin Exp Allergy. 2018 Dec;48(12):1748-1751. doi: 10.1111/cea.13257. Epub 2018 Sep 14. No abstract available.


Underdiagnosis and Overdiagnosis of Chronic Obstructive Pulmonary Disease.

Diab N, Gershon AS, Sin DD, Tan WC, Bourbeau J, Boulet LP, Aaron SD.

Am J Respir Crit Care Med. 2018 Nov 1;198(9):1130-1139. doi: 10.1164/rccm.201804-0621CI.


Patient preferences for a touch screen tablet-based asthma questionnaire.

Gupta S, Lam Shin Cheung V, Kastner M, Straus S, Kaplan A, Boulet LP, Sale JEM.

J Asthma. 2019 Jul;56(7):771-781. doi: 10.1080/02770903.2018.1490750. Epub 2018 Sep 28.


Genetic variants with gene regulatory effects are associated with diisocyanate-induced asthma.

Bernstein DI, Lummus ZL, Kesavalu B, Yao J, Kottyan L, Miller D, Cartier A, Cruz MJ, Lemiere C, Muñoz X, Quirce S, Tarlo S, Sastre J, Boulet LP, Weirauch MT, Kaufman K.

J Allergy Clin Immunol. 2018 Sep;142(3):959-969. doi: 10.1016/j.jaci.2018.06.022. Epub 2018 Jun 30.


Comparative impact of two continuing education activities targeted at COPD educators on educational outcomes: protocol for a non-randomized controlled study using mixed methods.

Gagné M, Moisan J, Lauzier S, Hamel C, Côté P, Bourbeau J, Boulet LP.

BMC Health Serv Res. 2018 Jun 18;18(1):460. doi: 10.1186/s12913-018-3284-6.


Between-Visit Variability in FEV1 as a Diagnostic Test for Asthma in Adults.

Dean BW, Birnie EE, Whitmore GA, Vandemheen KL, Boulet LP, FitzGerald JM, Ainslie M, Gupta S, Lemiere C, Field SK, McIvor RA, Hernandez P, Mayers I, Aaron SD; Canadian Respiratory Research Network.

Ann Am Thorac Soc. 2018 Sep;15(9):1039-1046. doi: 10.1513/AnnalsATS.201803-211OC.


Inhaled Glucocorticoids in Asthma.

Boulet LP, Gupta S, FitzGerald JM.

N Engl J Med. 2018 May 24;378(21):2050-1. doi: 10.1056/NEJMc1804801. No abstract available.


Underdiagnosis and Overdiagnosis of Asthma.

Aaron SD, Boulet LP, Reddel HK, Gershon AS.

Am J Respir Crit Care Med. 2018 Oct 15;198(8):1012-1020. doi: 10.1164/rccm.201804-0682CI.


Patient-reported outcome instruments that evaluate adherence behaviours in adults with asthma: a systematic review of measurement properties.

Gagné M, Boulet LP, Pérez N, Moisan J.

Br J Clin Pharmacol. 2018 Sep;84(9):1928-1940. doi: 10.1111/bcp.13623. Epub 2018 Jun 26. Review.


Asthma-COPD Overlap Phenotypes and Smoking :Comparative features of asthma in smoking or non-smoking patients with an incomplete reversibility of airway obstruction.

Boulet LP, Boulay MÈ, Dérival JL, Milot J, Lepage J, Bilodeau L, Maltais F.

COPD. 2018 Apr;15(2):130-138. doi: 10.1080/15412555.2017.1395834. Epub 2018 Apr 23.


Exercise and Asthma.

Côté A, Turmel J, Boulet LP.

Semin Respir Crit Care Med. 2018 Feb;39(1):19-28. doi: 10.1055/s-0037-1606215. Epub 2018 Feb 10. Review.


The effects of a CCR3 inhibitor, AXP1275, on allergen-induced airway responses in adults with mild-to-moderate atopic asthma.

Gauvreau GM, FitzGerald JM, Boulet LP, Watson RM, Hui L, Villineuve H, Scime TX, Schlatman AR, Obminski C, Kum J, Boehme S, Ly TW, Bacon KB, O'Byrne PM.

Clin Exp Allergy. 2018 Apr;48(4):445-451. doi: 10.1111/cea.13114. Epub 2018 Mar 13.


Benralizumab attenuates airway eosinophilia in prednisone-dependent asthma.

Sehmi R, Lim HF, Mukherjee M, Huang C, Radford K, Newbold P, Boulet LP, Dorscheid D, Martin JG, Nair P.

J Allergy Clin Immunol. 2018 Apr;141(4):1529-1532.e8. doi: 10.1016/j.jaci.2018.01.008. Epub 2018 Jan 31. No abstract available.


Sputum cytology during late-phase responses to inhalation challenge with different allergens.

Revez JA, Killian KJ, O'Byrne PM, Boulet LP, Upham JW, Gauvreau GM, Ferreira MAR.

Allergy. 2018 Jul;73(7):1470-1478. doi: 10.1111/all.13415. Epub 2018 Feb 6.


War-time asthma: lessons from Syria.

Boulet LP.

J Thorac Dis. 2017 Sep;9(9):3412-3414. doi: 10.21037/jtd.2017.08.91. No abstract available.


Asthma control and action plans.

Kouri A, Boulet LP, Kaplan A, Gupta S.

Eur Respir J. 2017 Dec 7;50(6). pii: 1701883. doi: 10.1183/13993003.01883-2017. Print 2017 Dec. No abstract available.


Novel Blood-based Transcriptional Biomarker Panels Predict the Late-Phase Asthmatic Response.

Singh A, Shannon CP, Kim YW, Yang CX, Balshaw R, Cohen Freue GV, Gauvreau GM, FitzGerald JM, Boulet LP, O'Byrne PM, Tebbutt SJ.

Am J Respir Crit Care Med. 2018 Feb 15;197(4):450-462. doi: 10.1164/rccm.201701-0110OC.


Airway remodeling in asthma: update on mechanisms and therapeutic approaches.

Boulet LP.

Curr Opin Pulm Med. 2018 Jan;24(1):56-62. doi: 10.1097/MCP.0000000000000441. Review.


Validation of the patient-completed asthma knowledge questionnaire (PAKQ).

Beaurivage D, Boulet LP, Foster JM, Gibson PG, McDonald VM.

J Asthma. 2018 Feb;55(2):169-179. doi: 10.1080/02770903.2017.1318914. Epub 2017 Oct 26.


Comparative features of Asthma with frequent or infrequent exacerbations: A longitudinal study of retrospective and prospective events.

Boulay MÈ, Pruneau-Pomerleau C, Villeneuve H, Deschesnes F, Ringuette L, Boulet LP.

J Asthma. 2018 Mar;55(3):231-243. doi: 10.1080/02770903.2017.1323918. Epub 2017 Oct 11.


A unique event for the francophone respiratory community.

Boulet LP, Bissonnette E, Humbert M, Maître B, Pigearias B.

Eur Respir J. 2017 Oct 5;50(4). pii: 1701479. doi: 10.1183/13993003.01479-2017. Print 2017 Oct. No abstract available.


Comparative Clinical, Physiological, and Inflammatory Characteristics of Elderly Subjects With or Without Asthma and Young Subjects With Asthma.

Boulet LP, Robitaille C, Deschesnes F, Villeneuve H, Boulay MÈ.

Chest. 2017 Dec;152(6):1203-1213. doi: 10.1016/j.chest.2017.09.019. Epub 2017 Sep 20.


Methacholine Challenge: Comparison of Airway Responsiveness Produced by a Vibrating Mesh Nebulizer Versus a Jet Nebulizer.

Blais CM, Cockcroft DW, Veilleux J, Boulay MÈ, Boulet LP, Gauvreau GM, Scime TX, Watson RM, O'Byrne PM, Davis BE.

J Aerosol Med Pulm Drug Deliv. 2018 Apr;31(2):88-93. doi: 10.1089/jamp.2017.1392. Epub 2017 Aug 16.


The Quebec Respiratory Health Education Network: Integrating a model of self-management education in COPD primary care.

Bourbeau J, Farias R, Li PZ, Gauthier G, Battisti L, Chabot V, Beauchesne MF, Villeneuve D, Côté P, Boulet LP.

Chron Respir Dis. 2018 May;15(2):103-113. doi: 10.1177/1479972317723237. Epub 2017 Jul 27.


Implementation of asthma clinical practice guidelines in primary care: A cross-sectional study based on the Knowledge-to-Action Cycle.

Gagné ME, Boulet LP.

J Asthma. 2018 Mar;55(3):310-317. doi: 10.1080/02770903.2017.1323919. Epub 2017 May 26.


Factors associated with adherence to asthma treatment with inhaled corticosteroids: A cross-sectional exploratory study.

Adouni Lawani M, Zongo F, Breton MC, Moisan J, Grégoire JP, Dorval E, Boulet LP, Jobin MS, Guénette L.

J Asthma. 2018 Mar;55(3):318-329. doi: 10.1080/02770903.2017.1326131. Epub 2017 May 26.


An evidence-based, point-of-care tool to guide completion of asthma action plans in practice.

Kouri A, Boulet LP, Kaplan A, Gupta S.

Eur Respir J. 2017 May 1;49(5). pii: 1602238. doi: 10.1183/13993003.02238-2016. Print 2017 May. Review.


Assessment of Airway Distensibility by the Forced Oscillation Technique: Reproducible and Potentially Simplifiable.

Mailhot-Larouche S, Lachance M, Bullone M, Henry C, Dandurand RJ, Boulet LP, Laviolette M, King GG, Farah CS, Bossé Y.

Front Physiol. 2017 Apr 12;8:223. doi: 10.3389/fphys.2017.00223. eCollection 2017.


Acute effects of bronchial thermoplasty: a matter of concern or an indicator of possible benefit to small airways?

Boulet LP, Laviolette M.

Eur Respir J. 2017 Mar 15;49(3). pii: 1700029. doi: 10.1183/13993003.00029-2017. Print 2017 Mar. No abstract available.


Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

Bousquet J, Farrell J, Crooks G, Hellings P, Bel EH, Bewick M, Chavannes NH, de Sousa JC, Cruz AA, Haahtela T, Joos G, Khaltaev N, Malva J, Muraro A, Nogues M, Palkonen S, Pedersen S, Robalo-Cordeiro C, Samolinski B, Strandberg T, Valiulis A, Yorgancioglu A, Zuberbier T, Bedbrook A, Aberer W, Adachi M, Agusti A, Akdis CA, Akdis M, Ankri J, Alonso A, Annesi-Maesano I, Ansotegui IJ, Anto JM, Arnavielhe S, Arshad H, Bai C, Baiardini I, Bachert C, Baigenzhin AK, Barbara C, Bateman ED, Beghé B, Kheder AB, Bennoor KS, Benson M, Bergmann KC, Bieber T, Bindslev-Jensen C, Bjermer L, Blain H, Blasi F, Boner AL, Bonini M, Bonini S, Bosnic-Anticevitch S, Boulet LP, Bourret R, Bousquet PJ, Braido F, Briggs AH, Brightling CE, Brozek J, Buhl R, Burney PG, Bush A, Caballero-Fonseca F, Caimmi D, Calderon MA, Calverley PM, Camargos PAM, Canonica GW, Camuzat T, Carlsen KH, Carr W, Carriazo A, Casale T, Cepeda Sarabia AM, Chatzi L, Chen YZ, Chiron R, Chkhartishvili E, Chuchalin AG, Chung KF, Ciprandi G, Cirule I, Cox L, Costa DJ, Custovic A, Dahl R, Dahlen SE, Darsow U, De Carlo G, De Blay F, Dedeu T, Deleanu D, De Manuel Keenoy E, Demoly P, Denburg JA, Devillier P, Didier A, Dinh-Xuan AT, Djukanovic R, Dokic D, Douagui H, Dray G, Dubakiene R, Durham SR, Dykewicz MS, El-Gamal Y, Emuzyte R, Fabbri LM, Fletcher M, Fiocchi A, Fink Wagner A, Fonseca J, Fokkens WJ, Forastiere F, Frith P, Gaga M, Gamkrelidze A, Garces J, Garcia-Aymerich J, Gemicioğlu B, Gereda JE, González Diaz S, Gotua M, Grisle I, Grouse L, Gutter Z, Guzmán MA, Heaney LG, Hellquist-Dahl B, Henderson D, Hendry A, Heinrich J, Heve D, Horak F, Hourihane JOB, Howarth P, Humbert M, Hyland ME, Illario M, Ivancevich JC, Jardim JR, Jares EJ, Jeandel C, Jenkins C, Johnston SL, Jonquet O, Julge K, Jung KS, Just J, Kaidashev I, Khaitov MR, Kalayci O, Kalyoncu AF, Keil T, Keith PK, Klimek L, Koffi N'Goran B, Kolek V, Koppelman GH, Kowalski ML, Kull I, Kuna P, Kvedariene V, Lambrecht B, Lau S, Larenas-Linnemann D, Laune D, Le LTT, Lieberman P, Lipworth B, Li J, Lodrup Carlsen K, Louis R, MacNee W, Magard Y, Magnan A, Mahboub B, Mair A, Majer I, Makela MJ, Manning P, Mara S, Marshall GD, Masjedi MR, Matignon P, Maurer M, Mavale-Manuel S, Melén E, Melo-Gomes E, Meltzer EO, Menzies-Gow A, Merk H, Michel JP, Miculinic N, Mihaltan F, Milenkovic B, Mohammad GMY, Molimard M, Momas I, Montilla-Santana A, Morais-Almeida M, Morgan M, Mösges R, Mullol J, Nafti S, Namazova-Baranova L, Naclerio R, Neou A, Neffen H, Nekam K, Niggemann B, Ninot G, Nyembue TD, O'Hehir RE, Ohta K, Okamoto Y, Okubo K, Ouedraogo S, Paggiaro P, Pali-Schöll I, Panzner P, Papadopoulos N, Papi A, Park HS, Passalacqua G, Pavord I, Pawankar R, Pengelly R, Pfaar O, Picard R, Pigearias B, Pin I, Plavec D, Poethig D, Pohl W, Popov TA, Portejoie F, Potter P, Postma D, Price D, Rabe KF, Raciborski F, Radier Pontal F, Repka-Ramirez S, Reitamo S, Rennard S, Rodenas F, Roberts J, Roca J, Rodriguez Mañas L, Rolland C, Roman Rodriguez M, Romano A, Rosado-Pinto J, Rosario N, Rosenwasser L, Rottem M, Ryan D, Sanchez-Borges M, Scadding GK, Schunemann HJ, Serrano E, Schmid-Grendelmeier P, Schulz H, Sheikh A, Shields M, Siafakas N, Sibille Y, Similowski T, Simons FER, Sisul JC, Skrindo I, Smit HA, Solé D, Sooronbaev T, Spranger O, Stelmach R, Sterk PJ, Sunyer J, Thijs C, To T, Todo-Bom A, Triggiani M, Valenta R, Valero AL, Valia E, Valovirta E, Van Ganse E, van Hage M, Vandenplas O, Vasankari T, Vellas B, Vestbo J, Vezzani G, Vichyanond P, Viegi G, Vogelmeier C, Vontetsianos T, Wagenmann M, Wallaert B, Walker S, Wang DY, Wahn U, Wickman M, Williams DM, Williams S, Wright J, Yawn BP, Yiallouros PK, Yusuf OM, Zaidi A, Zar HJ, Zernotti ME, Zhang L, Zhong N, Zidarn M, Mercier J.

Clin Transl Allergy. 2017 Feb 20;7:5. doi: 10.1186/s13601-016-0135-6. eCollection 2017.


Methacholine challenge tests to demonstrate therapeutic equivalence of terbutaline sulfate via different Turbuhaler® devices in patients with mild to moderate asthma: Appraisal of a four-way crossover design.

Bjermer L, Gauvreau GM, Postma DS, O'Byrne PM, van den Berge M, Boulet LP, Beckman O, Persson T, Román J, Carlholm M, Schützer KM, Eckerwall G.

Pulm Pharmacol Ther. 2017 Jun;44:1-6. doi: 10.1016/j.pupt.2017.02.004. Epub 2017 Feb 20.


Acute effects of nicotine-free and flavour-free electronic cigarette use on lung functions in healthy and asthmatic individuals.

Boulay MÈ, Henry C, Bossé Y, Boulet LP, Morissette MC.

Respir Res. 2017 Feb 10;18(1):33. doi: 10.1186/s12931-017-0518-9.

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