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Items: 21


DdlR, an essential transcriptional regulator of peptidoglycan biosynthesis in Clostridioides difficile.

Bouillaut L, Newton W, Sonenshein AL, Belitsky BR.

Mol Microbiol. 2019 Nov;112(5):1453-1470. doi: 10.1111/mmi.14371. Epub 2019 Sep 13.


Role of the global regulator Rex in control of NAD+ -regeneration in Clostridioides (Clostridium) difficile.

Bouillaut L, Dubois T, Francis MB, Daou N, Monot M, Sorg JA, Sonenshein AL, Dupuy B.

Mol Microbiol. 2019 Jun;111(6):1671-1688. doi: 10.1111/mmi.14245. Epub 2019 Apr 2.


Impact of CodY protein on metabolism, sporulation and virulence in Clostridioides difficile ribotype 027.

Daou N, Wang Y, Levdikov VM, Nandakumar M, Livny J, Bouillaut L, Blagova E, Zhang K, Belitsky BR, Rhee K, Wilkinson AJ, Sun X, Sonenshein AL.

PLoS One. 2019 Jan 30;14(1):e0206896. doi: 10.1371/journal.pone.0206896. eCollection 2019.


Oral Immunization with Nontoxigenic Clostridium difficile Strains Expressing Chimeric Fragments of TcdA and TcdB Elicits Protective Immunity against C. difficile Infection in Both Mice and Hamsters.

Wang Y, Wang S, Bouillaut L, Li C, Duan Z, Zhang K, Ju X, Tzipori S, Sonenshein AL, Sun X.

Infect Immun. 2018 Oct 25;86(11). pii: e00489-18. doi: 10.1128/IAI.00489-18. Print 2018 Nov.


Using CRISPR-Cas9-mediated genome editing to generate C. difficile mutants defective in selenoproteins synthesis.

McAllister KN, Bouillaut L, Kahn JN, Self WT, Sorg JA.

Sci Rep. 2017 Nov 7;7(1):14672. doi: 10.1038/s41598-017-15236-5.


NprR, a moonlighting quorum sensor shifting from a phosphatase activity to a transcriptional activator.

Perchat S, Talagas A, Zouhir S, Poncet S, Bouillaut L, Nessler S, Lereclus D.

Microb Cell. 2016 Nov 4;3(11):573-575. doi: 10.15698/mic2016.11.542.


Control of Clostridium difficile Physiopathology in Response to Cysteine Availability.

Dubois T, Dancer-Thibonnier M, Monot M, Hamiot A, Bouillaut L, Soutourina O, Martin-Verstraete I, Dupuy B.

Infect Immun. 2016 Jul 21;84(8):2389-405. doi: 10.1128/IAI.00121-16. Print 2016 Aug.


CodY-Dependent Regulation of Sporulation in Clostridium difficile.

Nawrocki KL, Edwards AN, Daou N, Bouillaut L, McBride SM.

J Bacteriol. 2016 Jul 13;198(15):2113-30. doi: 10.1128/JB.00220-16. Print 2016 Aug 1.


Effects of surotomycin on Clostridium difficile viability and toxin production in vitro.

Bouillaut L, McBride S, Sorg JA, Schmidt DJ, Suarez JM, Tzipori S, Mascio C, Chesnel L, Sonenshein AL.

Antimicrob Agents Chemother. 2015 Jul;59(7):4199-205. doi: 10.1128/AAC.00275-15. Epub 2015 May 4.


Integration of metabolism and virulence in Clostridium difficile.

Bouillaut L, Dubois T, Sonenshein AL, Dupuy B.

Res Microbiol. 2015 May;166(4):375-83. doi: 10.1016/j.resmic.2014.10.002. Epub 2014 Oct 15. Review.


An optimized, synthetic DNA vaccine encoding the toxin A and toxin B receptor binding domains of Clostridium difficile induces protective antibody responses in vivo.

Baliban SM, Michael A, Shammassian B, Mudakha S, Khan AS, Cocklin S, Zentner I, Latimer BP, Bouillaut L, Hunter M, Marx P, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, Kutzler MA.

Infect Immun. 2014 Oct;82(10):4080-91. doi: 10.1128/IAI.01950-14. Epub 2014 Jul 14.


Carvacrol and trans-cinnamaldehyde reduce Clostridium difficile toxin production and cytotoxicity in vitro.

Mooyottu S, Kollanoor-Johny A, Flock G, Bouillaut L, Upadhyay A, Sonenshein AL, Venkitanarayanan K.

Int J Mol Sci. 2014 Mar 12;15(3):4415-30. doi: 10.3390/ijms15034415.


Proline-dependent regulation of Clostridium difficile Stickland metabolism.

Bouillaut L, Self WT, Sonenshein AL.

J Bacteriol. 2013 Feb;195(4):844-54. doi: 10.1128/JB.01492-12. Epub 2012 Dec 7.


Fidaxomicin inhibits toxin production in Clostridium difficile.

Babakhani F, Bouillaut L, Sears P, Sims C, Gomez A, Sonenshein AL.

J Antimicrob Chemother. 2013 Mar;68(3):515-22. doi: 10.1093/jac/dks450. Epub 2012 Dec 2.


Use of a mariner-based transposon mutagenesis system to isolate Clostridium perfringens mutants deficient in gliding motility.

Liu H, Bouillaut L, Sonenshein AL, Melville SB.

J Bacteriol. 2013 Feb;195(3):629-36. doi: 10.1128/JB.01288-12. Epub 2012 Nov 30.


Fidaxomicin inhibits spore production in Clostridium difficile.

Babakhani F, Bouillaut L, Gomez A, Sears P, Nguyen L, Sonenshein AL.

Clin Infect Dis. 2012 Aug;55 Suppl 2:S162-9. doi: 10.1093/cid/cis453.


Genetic manipulation of Clostridium difficile.

Bouillaut L, McBride SM, Sorg JA.

Curr Protoc Microbiol. 2011 Feb;Chapter 9:Unit 9A.2. doi: 10.1002/9780471729259.mc09a02s20.


Molecular basis for group-specific activation of the virulence regulator PlcR by PapR heptapeptides.

Bouillaut L, Perchat S, Arold S, Zorrilla S, Slamti L, Henry C, Gohar M, Declerck N, Lereclus D.

Nucleic Acids Res. 2008 Jun;36(11):3791-801. doi: 10.1093/nar/gkn149. Epub 2008 May 20.


Structure of PlcR: Insights into virulence regulation and evolution of quorum sensing in Gram-positive bacteria.

Declerck N, Bouillaut L, Chaix D, Rugani N, Slamti L, Hoh F, Lereclus D, Arold ST.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18490-5. Epub 2007 Nov 12.


Growth-related variations in the Bacillus cereus secretome.

Gilois N, Ramarao N, Bouillaut L, Perchat S, Aymerich S, Nielsen-Leroux C, Lereclus D, Gohar M.

Proteomics. 2007 May;7(10):1719-28.


FlhA influences Bacillus thuringiensis PlcR-regulated gene transcription, protein production, and virulence.

Bouillaut L, Ramarao N, Buisson C, Gilois N, Gohar M, Lereclus D, Nielsen-Leroux C.

Appl Environ Microbiol. 2005 Dec;71(12):8903-10.

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