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Items: 1 to 50 of 148

1.

Evolution of characteristics of women with endometrial cancer during a 40 years study period.

Lorphelin H, Rossard L, Rua C, Arbion F, Bougnoux P, Body G, Ouldamer L.

J Gynecol Obstet Hum Reprod. 2019 Sep;48(7):489-494. doi: 10.1016/j.jogoh.2019.04.006. Epub 2019 Apr 12.

PMID:
30986541
2.

Low eicosapentaenoic acid and gamma-linolenic acid levels in breast adipose tissue are associated with inflammatory breast cancer.

Chas M, Goupille C, Arbion F, Bougnoux P, Pinault M, Jourdan ML, Chevalier S, Ouldamer L.

Breast. 2019 Jun;45:113-117. doi: 10.1016/j.breast.2019.04.001. Epub 2019 Apr 1.

PMID:
30959386
3.

SK3 Gene Polymorphism Is Associated with Taxane Neurotoxicity and Cell Calcium Homeostasis.

Rua C, Guéguinou M, Soubai I, Viel E, Potier-Cartereau M, Chantome A, Barbe C, Bougnoux P, Barin-Le Guellec C, Vandier C.

Clin Cancer Res. 2018 Nov 1;24(21):5313-5320. doi: 10.1158/1078-0432.CCR-18-0870. Epub 2018 Jul 23.

4.

Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy.

Jaffrès PA, Gajate C, Bouchet AM, Couthon-Gourvès H, Chantôme A, Potier-Cartereau M, Besson P, Bougnoux P, Mollinedo F, Vandier C.

Pharmacol Ther. 2016 Sep;165:114-31. doi: 10.1016/j.pharmthera.2016.06.003. Epub 2016 Jun 8. Review.

PMID:
27288726
5.

SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.

Guéguinou M, Harnois T, Crottes D, Uguen A, Deliot N, Gambade A, Chantôme A, Haelters JP, Jaffrès PA, Jourdan ML, Weber G, Soriani O, Bougnoux P, Mignen O, Bourmeyster N, Constantin B, Lecomte T, Vandier C, Potier-Cartereau M.

Oncotarget. 2016 Jun 14;7(24):36168-36184. doi: 10.18632/oncotarget.8786.

6.

Long chain n-3 polyunsaturated fatty acids increase the efficacy of docetaxel in mammary cancer cells by downregulating Akt and PKCε/δ-induced ERK pathways.

Chauvin L, Goupille C, Blanc C, Pinault M, Domingo I, Guimaraes C, Bougnoux P, Chevalier S, Mahéo K.

Biochim Biophys Acta. 2016 Apr;1861(4):380-90. doi: 10.1016/j.bbalip.2016.01.012. Epub 2016 Jan 26.

PMID:
26821209
7.

N-3 Polyunsaturated Fatty Acids of Marine Origin and Multifocality in Human Breast Cancer.

Ouldamer L, Goupille C, Vildé A, Arbion F, Body G, Chevalier S, Cottier JP, Bougnoux P.

PLoS One. 2016 Jan 26;11(1):e0147148. doi: 10.1371/journal.pone.0147148. eCollection 2016.

8.

NMR-Based Lipidomic Approach To Evaluate Controlled Dietary Intake of Lipids in Adipose Tissue of a Rat Mammary Tumor Model.

Ouldamer L, Nadal-Desbarats L, Chevalier S, Body G, Goupille C, Bougnoux P.

J Proteome Res. 2016 Mar 4;15(3):868-78. doi: 10.1021/acs.jproteome.5b00788. Epub 2016 Feb 12.

PMID:
26754345
9.

In vivo MR spectroscopy of human breast tissue: quantification of fatty acid composition at a clinical field strength (3 T).

Coum A, Ouldamer L, Noury F, Barantin L, Saint-Hilaire A, Vilde A, Bougnoux P, Gambarota G.

MAGMA. 2016 Feb;29(1):1-4. doi: 10.1007/s10334-015-0506-3. Epub 2016 Jan 2.

PMID:
26724927
10.

Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonization.

Driffort V, Gillet L, Bon E, Marionneau-Lambot S, Oullier T, Joulin V, Collin C, Pagès JC, Jourdan ML, Chevalier S, Bougnoux P, Le Guennec JY, Besson P, Roger S.

Mol Cancer. 2014 Dec 11;13:264. doi: 10.1186/1476-4598-13-264.

11.

Use of [(18)F]-FDG PET to predict response to neoadjuvant trastuzumab and docetaxel in patients with HER2-positive breast cancer, and addition of bevacizumab to neoadjuvant trastuzumab and docetaxel in [(18)F]-FDG PET-predicted non-responders (AVATAXHER): an open-label, randomised phase 2 trial.

Coudert B, Pierga JY, Mouret-Reynier MA, Kerrou K, Ferrero JM, Petit T, Kerbrat P, Dupré PF, Bachelot T, Gabelle P, Giard S, Coeffic D, Bougnoux P, Prevost JB, Paintaud G, Thibault G, Hernandez J, Coudert M, Arnould L, Berriolo-Riedinger A.

Lancet Oncol. 2014 Dec;15(13):1493-1502. doi: 10.1016/S1470-2045(14)70475-9. Epub 2014 Oct 30.

PMID:
25456368
12.

Lipid rafts, KCa/ClCa/Ca2+ channel complexes and EGFR signaling: Novel targets to reduce tumor development by lipids?

Guéguinou M, Gambade A, Félix R, Chantôme A, Fourbon Y, Bougnoux P, Weber G, Potier-Cartereau M, Vandier C.

Biochim Biophys Acta. 2015 Oct;1848(10 Pt B):2603-20. doi: 10.1016/j.bbamem.2014.10.036. Epub 2014 Nov 4. Review.

13.

[Reply to « Why is it difficult to implement biomedical policy? The ase of the Cancéropôles, the French cancer organizations », by Audrey Vézian, Med Sci (Paris) 2014 Aug-Sep; 30 (8-9) : 803-7].

Chabannon C, Bougnoux P, Favre G, Formstecher P, Laurent-Puig P, Oudet P, Trillet-Lenoir V.

Med Sci (Paris). 2014 Oct;30(10):925. doi: 10.1051/medsci/20143010022. Epub 2014 Oct 14. French.

14.

Radiotherapy associated with concurrent bevacizumab in patients with non-metastatic breast cancer.

Pernin V, Belin L, Cottu P, Bontemps P, Lemanski C, De La Lande B, Baumann P, Missohou F, Levy C, Peignaux K, Bougnoux P, Denis F, Bollet M, Dendale R, Vago NA, Campana F, Fourquet A, Kirova YM.

Breast. 2014 Dec;23(6):816-20. doi: 10.1016/j.breast.2014.08.015. Epub 2014 Sep 26.

PMID:
25260760
16.

Suppression of PPARβ, and DHA treatment, inhibit NaV1.5 and NHE-1 pro-invasive activities.

Wannous R, Bon E, Gillet L, Chamouton J, Weber G, Brisson L, Goré J, Bougnoux P, Besson P, Roger S, Chevalier S.

Pflugers Arch. 2015 Jun;467(6):1249-59. doi: 10.1007/s00424-014-1573-4. Epub 2014 Jul 15.

PMID:
25017107
17.

KCa and Ca(2+) channels: the complex thought.

Guéguinou M, Chantôme A, Fromont G, Bougnoux P, Vandier C, Potier-Cartereau M.

Biochim Biophys Acta. 2014 Oct;1843(10):2322-33. doi: 10.1016/j.bbamcr.2014.02.019. Epub 2014 Mar 6. Review.

18.

Cardiolipin content is involved in liver mitochondrial energy wasting associated with cancer-induced cachexia without the involvement of adenine nucleotide translocase.

Julienne CM, Tardieu M, Chevalier S, Pinault M, Bougnoux P, Labarthe F, Couet C, Servais S, Dumas JF.

Biochim Biophys Acta. 2014 May;1842(5):726-33. doi: 10.1016/j.bbadis.2014.02.003. Epub 2014 Feb 15.

19.

cAMP-PKA inhibition of SK3 channel reduced both Ca2+ entry and cancer cell migration by regulation of SK3-Orai1 complex.

Clarysse L, Guéguinou M, Potier-Cartereau M, Vandecasteele G, Bougnoux P, Chevalier S, Chantôme A, Vandier C.

Pflugers Arch. 2014 Oct;466(10):1921-32. doi: 10.1007/s00424-013-1435-5. Epub 2014 Jan 24.

PMID:
24458591
20.

PPARβ mRNA expression, reduced by n-3 PUFA diet in mammary tumor, controls breast cancer cell growth.

Wannous R, Bon E, Mahéo K, Goupille C, Chamouton J, Bougnoux P, Roger S, Besson P, Chevalier S.

Biochim Biophys Acta. 2013 Nov;1831(11):1618-25. doi: 10.1016/j.bbalip.2013.07.010. Epub 2013 Jul 30.

PMID:
23906790
21.

Pivotal role of the lipid Raft SK3-Orai1 complex in human cancer cell migration and bone metastases.

Chantôme A, Potier-Cartereau M, Clarysse L, Fromont G, Marionneau-Lambot S, Guéguinou M, Pagès JC, Collin C, Oullier T, Girault A, Arbion F, Haelters JP, Jaffrès PA, Pinault M, Besson P, Joulin V, Bougnoux P, Vandier C.

Cancer Res. 2013 Aug 1;73(15):4852-61. doi: 10.1158/0008-5472.CAN-12-4572. Epub 2013 Jun 17.

22.

Everolimus as second- or third-line treatment of advanced endometrial cancer: ENDORAD, a phase II trial of GINECO.

Ray-Coquard I, Favier L, Weber B, Roemer-Becuwe C, Bougnoux P, Fabbro M, Floquet A, Joly F, Plantade A, Paraiso D, Pujade-Lauraine E.

Br J Cancer. 2013 May 14;108(9):1771-7. doi: 10.1038/bjc.2013.183. Epub 2013 Apr 23.

23.

Phase II study of intravenous vinflunine after failure of first-line vinorelbine based regimen for advanced breast cancer.

Blasinska-Morawiec M, Tubiana-Mathieu N, Fougeray R, Pinel MC, Bougnoux P.

Breast. 2013 Feb;22(1):58-63. doi: 10.1016/j.breast.2012.10.007. Epub 2012 Nov 26.

24.

DHA effect on chemotherapy-induced body weight loss: an exploratory study in a rodent model of mammary tumors.

Hajjaji N, Couet C, Besson P, Bougnoux P.

Nutr Cancer. 2012;64(7):1000-7. doi: 10.1080/01635581.2012.714832. Epub 2012 Oct 4.

PMID:
23035949
25.

Selective sensitization of tumors to chemotherapy by marine-derived lipids: a review.

Hajjaji N, Bougnoux P.

Cancer Treat Rev. 2013 Aug;39(5):473-88. doi: 10.1016/j.ctrv.2012.07.001. Epub 2012 Jul 31. Review.

PMID:
22850619
26.

Tumor and non-tumor tissues differential oxidative stress response to supplemental DHA and chemotherapy in rats.

Hajjaji N, Besson P, Bougnoux P.

Cancer Chemother Pharmacol. 2012 Jul;70(1):17-23. doi: 10.1007/s00280-012-1884-0. Epub 2012 May 18.

PMID:
22610354
27.

Non-invasive quantification of tumor vascular architecture during docetaxel-chemotherapy.

Mahéo K, Chevalier S, Vibet S, Bougnoux P, Richard S, Serrière S, Bleuzen A, Tranquart F, Goupille C.

Breast Cancer Res Treat. 2012 Aug;134(3):1013-25. doi: 10.1007/s10549-012-2015-7. Epub 2012 Mar 22.

PMID:
22438047
28.

Targeting SKCa channels in cancer: potential new therapeutic approaches.

Girault A, Haelters JP, Potier-Cartereau M, Chantôme A, Jaffrés PA, Bougnoux P, Joulin V, Vandier C.

Curr Med Chem. 2012;19(5):697-713. Review.

PMID:
22204342
29.

Reducing endothelial NOS activation and interstitial fluid pressure with n-3 PUFA offset tumor chemoresistance.

Kornfeld S, Goupille C, Vibet S, Chevalier S, Pinet A, Lebeau J, Tranquart F, Bougnoux P, Martel E, Maurin A, Richard S, Champeroux P, Mahéo K.

Carcinogenesis. 2012 Feb;33(2):260-7. doi: 10.1093/carcin/bgr274. Epub 2011 Nov 23.

PMID:
22114075
30.

New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis.

Girault A, Haelters JP, Potier-Cartereau M, Chantome A, Pinault M, Marionneau-Lambot S, Oullier T, Simon G, Couthon-Gourvès H, Jaffrès PA, Corbel B, Bougnoux P, Joulin V, Vandier C.

Curr Cancer Drug Targets. 2011 Nov;11(9):1111-25.

PMID:
21999627
31.

Determinants of DHA incorporation into tumor tissue during dietary DHA supplementation.

Hajjaji N, Schubnel V, Bougnoux P.

Lipids. 2011 Nov;46(11):1063-9. doi: 10.1007/s11745-011-3573-x. Epub 2011 Jun 3.

32.

Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study.

Cortes J, O'Shaughnessy J, Loesch D, Blum JL, Vahdat LT, Petrakova K, Chollet P, Manikas A, Diéras V, Delozier T, Vladimirov V, Cardoso F, Koh H, Bougnoux P, Dutcus CE, Seegobin S, Mir D, Meneses N, Wanders J, Twelves C; EMBRACE (Eisai Metastatic Breast Cancer Study Assessing Physician's Choice Versus E7389) investigators.

Lancet. 2011 Mar 12;377(9769):914-23. doi: 10.1016/S0140-6736(11)60070-6. Epub 2011 Mar 2.

PMID:
21376385
33.

Efficiency of oxidative phosphorylation in liver mitochondria is decreased in a rat model of peritoneal carcinosis.

Dumas JF, Goupille C, Julienne CM, Pinault M, Chevalier S, Bougnoux P, Servais S, Couet C.

J Hepatol. 2011 Feb;54(2):320-7. doi: 10.1016/j.jhep.2010.08.012. Epub 2010 Sep 19.

PMID:
21094554
34.

The SK3/K(Ca)2.3 potassium channel is a new cellular target for edelfosine.

Potier M, Chantome A, Joulin V, Girault A, Roger S, Besson P, Jourdan ML, LeGuennec JY, Bougnoux P, Vandier C.

Br J Pharmacol. 2011 Jan;162(2):464-79. doi: 10.1111/j.1476-5381.2010.01044.x.

35.

Altered SK3/KCa2.3-mediated migration in adenomatous polyposis coli (Apc) mutated mouse colon epithelial cells.

Potier M, Tran TA, Chantome A, Girault A, Joulin V, Bougnoux P, Vandier C, Pierre F.

Biochem Biophys Res Commun. 2010 Jun 18;397(1):42-7. doi: 10.1016/j.bbrc.2010.05.046. Epub 2010 May 26.

PMID:
20519134
36.

n-3 PUFA-enriched diet delays the occurrence of cancer cachexia in rat with peritoneal carcinosis.

Dumas JF, Goupille C, Pinault M, Fandeur L, Bougnoux P, Servais S, Couet C.

Nutr Cancer. 2010;62(3):343-50. doi: 10.1080/01635580903407080.

PMID:
20358472
37.

Beneficial effects of omega-3 long-chain fatty acids in breast cancer and cardiovascular diseases: voltage-gated sodium channels as a common feature?

Gillet L, Roger S, Bougnoux P, Le Guennec JY, Besson P.

Biochimie. 2011 Jan;93(1):4-6. doi: 10.1016/j.biochi.2010.02.005. Epub 2010 Feb 16. Review.

PMID:
20167245
38.

Phase II study of gefitinib in combination with paclitaxel (P) and carboplatin (C) as second-line therapy for ovarian, tubal or peritoneal adenocarcinoma (1839IL/0074).

Pautier P, Joly F, Kerbrat P, Bougnoux P, Fumoleau P, Petit T, Rixe O, Ringeisen F, Carrasco AT, Lhommé C.

Gynecol Oncol. 2010 Feb;116(2):157-62. doi: 10.1016/j.ygyno.2009.10.076.

PMID:
20109725
39.

Improving outcome of chemotherapy of metastatic breast cancer by docosahexaenoic acid: a phase II trial.

Bougnoux P, Hajjaji N, Ferrasson MN, Giraudeau B, Couet C, Le Floch O.

Br J Cancer. 2009 Dec 15;101(12):1978-85. doi: 10.1038/sj.bjc.6605441. Epub 2009 Nov 17.

40.

Fatty acids and breast cancer: sensitization to treatments and prevention of metastatic re-growth.

Bougnoux P, Hajjaji N, Maheo K, Couet C, Chevalier S.

Prog Lipid Res. 2010 Jan;49(1):76-86. doi: 10.1016/j.plipres.2009.08.003. Epub 2009 Aug 26. Review.

PMID:
19715726
41.

All-oral combination of oral vinorelbine and capecitabine as first-line chemotherapy in HER2-negative metastatic breast cancer: an International Phase II Trial.

Tubiana-Mathieu N, Bougnoux P, Becquart D, Chan A, Conte PF, Majois F, Espie M, Morand M, Vaissiere N, Villanova G.

Br J Cancer. 2009 Jul 21;101(2):232-7. doi: 10.1038/sj.bjc.6605156. Epub 2009 Jul 7.

42.

A universal formula based on cystatin C to perform individual dosing of carboplatin in normal weight, underweight, and obese patients.

Schmitt A, Gladieff L, Lansiaux A, Bobin-Dubigeon C, Etienne-Grimaldi MC, Boisdron-Celle M, Serre-Debauvais F, Pinguet F, Floquet A, Billaud E, Le Guellec C, Penel N, Campone M, Largillier R, Capitain O, Fabbro M, Houede N, Medioni J, Bougnoux P, Lochon I, Chatelut E.

Clin Cancer Res. 2009 May 15;15(10):3633-9. doi: 10.1158/1078-0432.CCR-09-0017. Epub 2009 Apr 28.

43.

On the mechanisms of ultrasound contrast agents-induced arrhythmias.

Tran TA, Le Guennec JY, Babuty D, Bougnoux P, Tranquart F, Bouakaz A.

Ultrasound Med Biol. 2009 Jun;35(6):1050-6. doi: 10.1016/j.ultrasmedbio.2008.11.015. Epub 2009 Feb 5.

PMID:
19195768
44.

Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells.

Gillet L, Roger S, Besson P, Lecaille F, Gore J, Bougnoux P, Lalmanach G, Le Guennec JY.

J Biol Chem. 2009 Mar 27;284(13):8680-91. doi: 10.1074/jbc.M806891200. Epub 2009 Jan 28.

45.

The lipidome as a composite biomarker of the modifiable part of the risk of breast cancer.

Bougnoux P, Hajjaji N, Couet C.

Prostaglandins Leukot Essent Fatty Acids. 2008 Sep-Nov;79(3-5):93-6. doi: 10.1016/j.plefa.2008.09.004. Epub 2008 Oct 18. Review.

PMID:
18930643
46.

Characterization of cell membrane response to ultrasound activated microbubbles.

Tran TA, Le Guennec JY, Bougnoux P, Tranquart F, Bouakaz A.

IEEE Trans Ultrason Ferroelectr Freq Control. 2008 Jan;55(1):43-9. doi: 10.1109/TUFFC.2008.615.

PMID:
18334312
47.

A well-tolerated 5-FU-based treatment subsequent to severe capecitabine-induced toxicity in a DPD-deficient patient.

Blasco H, Boisdron-Celle M, Bougnoux P, Calais G, Tournamille JF, Ciccolini J, Autret-Leca E, Le Guellec C.

Br J Clin Pharmacol. 2008 Jun;65(6):966-70. doi: 10.1111/j.1365-2125.2008.03106.x. Epub 2008 Feb 20. No abstract available.

48.

Sensitization by docosahexaenoic acid (DHA) of breast cancer cells to anthracyclines through loss of glutathione peroxidase (GPx1) response.

Vibet S, Goupille C, Bougnoux P, Steghens JP, Goré J, Mahéo K.

Free Radic Biol Med. 2008 Apr 1;44(7):1483-91. doi: 10.1016/j.freeradbiomed.2008.01.009. Epub 2008 Jan 26.

PMID:
18267129
49.

Dietary long-chain n-3 fatty acids modify blood and cardiac phospholipids and reduce protein kinase-C-delta and protein kinase-C-epsilon translocation.

Judé S, Martel E, Vincent F, Besson P, Couet C, Ogilvie GK, Pinault M, De Chalendar C, Bougnoux P, Richard S, Champeroux P, Crozatier B, Le Guennec JY.

Br J Nutr. 2007 Dec;98(6):1143-51. Epub 2007 Jul 30.

PMID:
17663802
50.

Increased BRCA1 protein in mammary tumours of rats fed marine omega-3 fatty acids.

Jourdan ML, Mahéo K, Barascu A, Goupille C, De Latour MP, Bougnoux P, Rio PG.

Oncol Rep. 2007 Apr;17(4):713-9.

PMID:
17342305

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