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Items: 1 to 50 of 62

1.

The impact of iodinated contrast media on intravascular and extravascular absorbed doses in X-ray imaging: A microdosimetric analysis.

Harbron RW, Ainsbury EA, Bouffler SD, Tanner RJ, Pearce MS, Eakins JS.

Phys Med. 2018 Feb;46:140-147. doi: 10.1016/j.ejmp.2018.02.001. Epub 2018 Feb 7.

PMID:
29519400
2.

Genotoxic effects of high dose rate X-ray and low dose rate gamma radiation in ApcMin/+ mice.

Graupner A, Eide DM, Brede DA, Ellender M, Lindbo Hansen E, Oughton DH, Bouffler SD, Brunborg G, Olsen AK.

Environ Mol Mutagen. 2017 Oct;58(8):560-569. doi: 10.1002/em.22121. Epub 2017 Aug 30.

3.

Enhanced radiation dose and DNA damage associated with iodinated contrast media in diagnostic X-ray imaging.

Harbron R, Ainsbury EA, Bouffler SD, Tanner RJ, Eakins JS, Pearce MS.

Br J Radiol. 2017 Nov;90(1079):20170028. doi: 10.1259/bjr.20170028. Epub 2017 Aug 22. Review.

4.

Transcriptomic and proteomic analysis of mouse radiation-induced acute myeloid leukaemia (AML).

Badie C, Blachowicz A, Barjaktarovic Z, Finnon R, Michaux A, Sarioglu H, Brown N, Manning G, Benotmane MA, Tapio S, Polanska J, Bouffler SD.

Oncotarget. 2016 Jun 28;7(26):40461-40480. doi: 10.18632/oncotarget.9626.

5.

Dose-rate effects in radiation biology and radiation protection.

Rühm W, Azizova TV, Bouffler SD, Little MP, Shore RE, Walsh L, Woloschak GE.

Ann ICRP. 2016 Jun;45(1_suppl):262-279. doi: 10.1177/0146645316629336.

PMID:
26960819
6.

Evidence for variation in human radiosensitivity and its potential impact on radiological protection.

Bouffler SD.

Ann ICRP. 2016 Jun;45(1 Suppl):280-9. doi: 10.1177/0146645315623158. Epub 2016 Mar 8. Review.

PMID:
26956676
7.

Radiation protection of the eye lens in medical workers--basis and impact of the ICRP recommendations.

Barnard SG, Ainsbury EA, Quinlan RA, Bouffler SD.

Br J Radiol. 2016;89(1060):20151034. doi: 10.1259/bjr.20151034. Epub 2016 Feb 1. Review.

8.
9.

The lens of the eye: exposures in the UK medical sector and mechanistic studies of radiation effects.

Bouffler SD, Peters S, Gilvin P, Slack K, Markiewicz E, Quinlan RA, Gillan J, Coster M, Barnard S, Rothkamm K, Ainsbury E.

Ann ICRP. 2015 Jun;44(1 Suppl):84-90. doi: 10.1177/0146645314560693. Epub 2015 Mar 10.

PMID:
25816262
10.

Potential protein activity modifications of amino acid variants in the human transcriptome.

Zyla J, Bulman RA, Badie C, Bouffler SD.

Acta Biochim Pol. 2015;62(1):57-61. Epub 2015 Feb 4.

11.

Live cell detection of chromosome 2 deletion and Sfpi1/PU1 loss in radiation-induced mouse acute myeloid leukaemia.

Olme CH, Finnon R, Brown N, Kabacik S, Bouffler SD, Badie C.

Leuk Res. 2013 Oct;37(10):1374-82. doi: 10.1016/j.leukres.2013.05.019. Epub 2013 Jun 25.

12.

Frequency of acute myeloid leukaemia-associated mouse chromosome 2 deletions in X-ray exposed immature haematopoietic progenitors and stem cells.

Olme CH, Brown N, Finnon R, Bouffler SD, Badie C.

Mutat Res. 2013 Aug 30;756(1-2):119-26. doi: 10.1016/j.mrgentox.2013.04.018. Epub 2013 May 9.

13.

Evidence relevant to untargeted and transgenerational effects in the offspring of irradiated parents.

Little MP, Goodhead DT, Bridges BA, Bouffler SD.

Mutat Res. 2013 Jul-Sep;753(1):50-67. doi: 10.1016/j.mrrev.2013.04.001. Epub 2013 May 4. Review.

14.

Comment on "dose-responses from multi-model inference for the non-cancer disease mortality of atomic bomb survivors" (Radiat. Environ. Biophys (2012) 51:165-178) by Schöllnberger et al.

Little MP, Azizova TV, Bazyka D, Bouffler SD, Cardis E, Chekin S, Chumak VV, Cucinotta FA, de Vathaire F, Hall P, Harrison JD, Hildebrandt G, Ivanov V, Kashcheev VV, Klymenko SV, Laurent O, Ozasa K, Tapio S, Taylor AM, Tzoulaki I, Vandoolaeghe WL, Wakeford R, Zablotska L, Zhang W, Lipshultz SE.

Radiat Environ Biophys. 2013 Mar;52(1):157-9. doi: 10.1007/s00411-012-0453-6. Epub 2013 Jan 8. No abstract available.

PMID:
23296519
15.

Systematic review and meta-analysis of circulatory disease from exposure to low-level ionizing radiation and estimates of potential population mortality risks.

Little MP, Azizova TV, Bazyka D, Bouffler SD, Cardis E, Chekin S, Chumak VV, Cucinotta FA, de Vathaire F, Hall P, Harrison JD, Hildebrandt G, Ivanov V, Kashcheev VV, Klymenko SV, Kreuzer M, Laurent O, Ozasa K, Schneider T, Tapio S, Taylor AM, Tzoulaki I, Vandoolaeghe WL, Wakeford R, Zablotska LB, Zhang W, Lipshultz SE.

Environ Health Perspect. 2012 Nov;120(11):1503-11. doi: 10.1289/ehp.1204982. Epub 2012 Jun 22. Review.

16.

Flt3-ITD mutations in a mouse model of radiation-induced acute myeloid leukaemia.

Finnon R, Brown N, Moody J, Badie C, Olme CH, Huiskamp R, Meijne E, Sutmuller M, Rosemann M, Bouffler SD.

Leukemia. 2012 Jun;26(6):1445-6. doi: 10.1038/leu.2011.377. Epub 2012 Jan 6. No abstract available.

17.

Intestinal tumours induced in Apc(Min/+) mice by X-rays and neutrons.

Ellender M, Harrison JD, Meijne E, Huiskamp R, Kozlowski RE, Haines JW, Edwards AA, Ainsbury EA, Moody JC, Bouffler SD, Cox R.

Int J Radiat Biol. 2011 Apr;87(4):385-99. doi: 10.3109/09553002.2011.542542. Epub 2011 Jan 10.

PMID:
21219111
18.

Xrcc2 modulates spontaneous and radiation-induced tumorigenesis in Apcmin/+ mice.

Haines JW, Coster MR, Adam J, Cheeseman M, Ainsbury EA, Thacker J, Bouffler SD.

Mol Cancer Res. 2010 Sep;8(9):1227-33. doi: 10.1158/1541-7786.MCR-10-0089. Epub 2010 Jul 29.

19.

Sfpi1/PU.1 mutations in mouse radiation-induced acute myeloid leukaemias affect mRNA and protein abundance and associate with disrupted transcription.

Brown NL, Finnon R, Bulman RA, Finnon P, Moody J, Bouffler SD, Badie C.

Leuk Res. 2011 Jan;35(1):126-32. doi: 10.1016/j.leukres.2010.06.015. Epub 2010 Jul 17.

PMID:
20638124
20.

Radiation cataractogenesis: a review of recent studies.

Ainsbury EA, Bouffler SD, Dörr W, Graw J, Muirhead CR, Edwards AA, Cooper J.

Radiat Res. 2009 Jul;172(1):1-9. doi: 10.1667/RR1688.1. Review.

PMID:
19580502
22.

Radiation leukemogenesis in mice: loss of PU.1 on chromosome 2 in CBA and C57BL/6 mice after irradiation with 1 GeV/nucleon 56Fe ions, X rays or gamma rays. Part I. Experimental observations.

Peng Y, Brown N, Finnon R, Warner CL, Liu X, Genik PC, Callan MA, Ray FA, Borak TB, Badie C, Bouffler SD, Ullrich RL, Bedford JS, Weil MM.

Radiat Res. 2009 Apr;171(4):474-83. doi: 10.1667/RR1547.1.

PMID:
19397448
23.

Risks associated with low doses and low dose rates of ionizing radiation: why linearity may be (almost) the best we can do.

Little MP, Wakeford R, Tawn EJ, Bouffler SD, Berrington de Gonzalez A.

Radiology. 2009 Apr;251(1):6-12. doi: 10.1148/radiol.2511081686. No abstract available.

24.

A possible role for telomerase RNA and telomere length in global mitotic recombination.

Bouffler SD, Finnon P, Blasco MA, Ainsbury E.

Cytogenet Genome Res. 2008;122(3-4):292-6. doi: 10.1159/000167815. Epub 2009 Jan 30.

PMID:
19188698
25.

TPD52 and NFKB1 gene expression levels correlate with G2 chromosomal radiosensitivity in lymphocytes of women with and at risk of hereditary breast cancer.

Sims AH, Finnon P, Miller CJ, Bouffler SD, Howell A, Scott D, Clarke RB.

Int J Radiat Biol. 2007 Jun;83(6):409-20.

PMID:
17487680
26.

Wavelength dependence of cellular responses in human melanocytes and melanoma cells following exposure to ultraviolet radiation.

Kowalczuk CI, Priestner MC, Pearson AJ, Saunders RD, Bouffler SD.

Int J Radiat Biol. 2006 Nov;82(11):781-92.

PMID:
17148262
27.

Plenary discussion--Experimental studies sessions I and II.

Bouffler SD, Saunders RD.

Prog Biophys Mol Biol. 2007 Jan-Apr;93(1-3):411-3. Epub 2006 Aug 10. No abstract available.

PMID:
16952389
28.

In utero and neonatal sensitivity of ApcMin/+ mice to radiation-induced intestinal neoplasia.

Ellender M, Harrison JD, Kozlowski R, Szłuińska M, Bouffler SD, Cox R.

Int J Radiat Biol. 2006 Mar;82(3):141-51.

PMID:
16638711
29.

Assessing radiation-associated mutational risk to the germline: repetitive DNA sequences as mutational targets and biomarkers.

Bouffler SD, Bridges BA, Cooper DN, Dubrova Y, McMillan TJ, Thacker J, Wright EG, Waters R.

Radiat Res. 2006 Mar;165(3):249-68. Review.

PMID:
16494513
30.

Locations of mouse DNA damage response and repair loci, and cancer risk modifiers.

Bulman RA, Dragani TA, Bouffler SD, Cox R.

DNA Repair (Amst). 2006 Feb 3;5(2):274-7. Epub 2005 Nov 11.

PMID:
16290248
31.

Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay.

Darakhshan F, Badie C, Moody J, Coster M, Finnon R, Finnon P, Edwards AA, Szluinska M, Skidmore CJ, Yoshida K, Ullrich R, Cox R, Bouffler SD.

Carcinogenesis. 2006 Feb;27(2):311-8. Epub 2005 Aug 10.

PMID:
16093251
32.

Direct single gene mutational events account for radiation-induced intestinal adenoma yields in Apc(Min/+) mice.

Ellender M, Harrison JD, Edwards AA, Bouffler SD, Cox R.

Radiat Res. 2005 May;163(5):552-6.

PMID:
15850417
33.

Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.

Espejel S, Franco S, Rodríguez-Perales S, Bouffler SD, Cigudosa JC, Blasco MA.

EMBO J. 2002 May 1;21(9):2207-19.

34.

Long but dysfunctional telomeres correlate with chromosomal radiosensitivity in a mouse AML cell line.

Finnon P, Wong HP, Silver AR, Slijepcevic P, Bouffler SD.

Int J Radiat Biol. 2001 Dec;77(12):1151-62.

PMID:
11747540
35.

Telomeric sequences, radiation sensitivity and genomic instability.

Bouffler SD, Blasco MA, Cox R, Smith PJ.

Int J Radiat Biol. 2001 Oct;77(10):995-1005. Review.

PMID:
11682005
36.

In utero haemopoietic sensitivity to alpha, beta or X-irradiation in CBA/H mice.

Kozlowski R, Bouffler SD, Haines JW, Harrison JD, Cox R.

Int J Radiat Biol. 2001 Jul;77(7):805-15.

PMID:
11454281
37.

Telomere length abnormalities in mammalian radiosensitive cells.

McIlrath J, Bouffler SD, Samper E, Cuthbert A, Wojcik A, Szumiel I, Bryant PE, Riches AC, Thompson A, Blasco MA, Newbold RF, Slijepcevic P.

Cancer Res. 2001 Feb 1;61(3):912-5.

38.
39.

Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals.

Goytisolo FA, Samper E, Martín-Caballero J, Finnon P, Herrera E, Flores JM, Bouffler SD, Blasco MA.

J Exp Med. 2000 Dec 4;192(11):1625-36.

40.

Evidence for Msh2 haploinsufficiency in mice revealed by MNU-induced sister-chromatid exchange analysis.

Bouffler SD, Hofland N, Cox R, Fodde R.

Br J Cancer. 2000 Nov;83(10):1291-4.

41.
42.

Involvement of telomeric sequences in chromosomal aberrations.

Bouffler SD.

Mutat Res. 1998 Aug 3;404(1-2):199-204. Review.

PMID:
9729384
43.

Telomere length, chromatin structure and chromosome fusigenic potential.

Slijepcevic P, Hande MP, Bouffler SD, Lansdorp P, Bryant PE.

Chromosoma. 1997 Dec;106(7):413-21.

PMID:
9391214
44.

Chromosome 2 hypersensitivity and clonal development in murine radiation acute myeloid leukaemia.

Bouffler SD, Meijne EI, Morris DJ, Papworth D.

Int J Radiat Biol. 1997 Aug;72(2):181-9.

PMID:
9269311
45.

The involvement of telomeric sequences in chromosomal aberrations.

Bouffler SD, Morgan WF, Pandita TK, Slijepcevic P.

Mutat Res. 1996 Nov;366(2):129-35. Review.

PMID:
9001579
46.

Chromosomal abnormalities in neutron-induced acute myeloid leukemias in CBA/H mice.

Bouffler SD, Meijne EI, Huiskamp R, Cox R.

Radiat Res. 1996 Sep;146(3):349-52.

PMID:
8752315
47.

Microsatellite analysis of recurrent chromosome 2 deletions in acute myeloid leukaemia induced by radiation in F1 hybrid mice.

Clark DJ, Meijne EI, Bouffler SD, Huiskamp R, Skidmore CJ, Cox R, Silver AR.

Genes Chromosomes Cancer. 1996 Aug;16(4):238-46.

PMID:
8875237
48.

Role of telomeric sequences in murine radiation-induced myeloid leukaemia.

Meijne EI, Silver AR, Bouffler SD, Morris DJ, van Kampen EW, Spanjer S, Huiskamp R, Cox R.

Genes Chromosomes Cancer. 1996 Aug;16(4):230-7.

PMID:
8875236
49.

Chromosomal mechanisms in murine radiation acute myeloid leukaemogenesis.

Bouffler SD, Breckon G, Cox R.

Carcinogenesis. 1996 Apr;17(4):655-9.

PMID:
8625474
50.

Spontaneous and ionizing radiation-induced chromosomal abnormalities in p53-deficient mice.

Bouffler SD, Kemp CJ, Balmain A, Cox R.

Cancer Res. 1995 Sep 1;55(17):3883-9.

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