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Items: 9


Genome-wide analysis of androgen receptor binding and transcriptomic analysis in mesenchymal subsets during prostate development.

Nash C, Boufaied N, Badescu D, Wang YC, Paliouras M, Trifiro M, Ragoussis I, Thomson AA.

Dis Model Mech. 2019 Jul 25;12(7). pii: dmm039297. doi: 10.1242/dmm.039297.


Development of a predictive model for stromal content in prostate cancer samples to improve signature performance.

Boufaied N, Takhar M, Nash C, Erho N, Bismar TA, Davicioni E, Thomson AA.

J Pathol. 2019 Jun 17. doi: 10.1002/path.5315. [Epub ahead of print]


Identification of genes expressed in a mesenchymal subset regulating prostate organogenesis using tissue and single cell transcriptomics.

Boufaied N, Nash C, Rochette A, Smith A, Orr B, Grace OC, Wang YC, Badescu D, Ragoussis J, Thomson AA.

Sci Rep. 2017 Nov 27;7(1):16385. doi: 10.1038/s41598-017-16685-8.


Genome-wide analysis of AR binding and comparison with transcript expression in primary human fetal prostate fibroblasts and cancer associated fibroblasts.

Nash C, Boufaied N, Mills IG, Franco OE, Hayward SW, Thomson AA.

Mol Cell Endocrinol. 2018 Aug 15;471:1-14. doi: 10.1016/j.mce.2017.05.006. Epub 2017 May 5.


Asporin is a stromally expressed marker associated with prostate cancer progression.

Rochette A, Boufaied N, Scarlata E, Hamel L, Brimo F, Whitaker HC, Ramos-Montoya A, Neal DE, Dragomir A, Aprikian A, Chevalier S, Thomson AA.

Br J Cancer. 2017 Mar 14;116(6):775-784. doi: 10.1038/bjc.2017.15. Epub 2017 Feb 2.


TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling.

Campbell PM, Boufaied N, Fiordalisi JJ, Cox AD, Falardeau P, Der CJ, Gourdeau H.

J Mol Signal. 2010 Nov 2;5:18. doi: 10.1186/1750-2187-5-18.


TLN-4601, a novel anticancer agent, inhibits Ras signaling post Ras prenylation and before MEK activation.

Boufaied N, Wioland MA, Falardeau P, Gourdeau H.

Anticancer Drugs. 2010 Jun;21(5):543-52. doi: 10.1097/CAD.0b013e328337f373.


High levels of oxidative stress globally inhibit gene transcription and histone acetylation.

Berthiaume M, Boufaied N, Moisan A, Gaudreau L.

DNA Cell Biol. 2006 Feb;25(2):124-34.


BRCA1 can stimulate gene transcription by a unique mechanism.

Nadeau G, Boufaied N, Moisan A, Lemieux KM, Cayanan C, Monteiro AN, Gaudreau L.

EMBO Rep. 2000 Sep;1(3):260-5.

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