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Prevalence, Incidence and Risk Factors for Overall, Physical and Cognitive Independence among those from exceptionally long-lived families: The Long Life Family Study.

Santanasto AJ, Marron MM, Boudreau RM, Feitosa MF, Wojczynski MK, Arbeev KG, Thyagarajan B, Schupf N, Stallard E, Sebastiani P, Cosentino S, Christensen K, Newman AB.

J Gerontol A Biol Sci Med Sci. 2019 May 14. pii: glz124. doi: 10.1093/gerona/glz124. [Epub ahead of print]


Metabolites Associated with Vigor to Frailty Among Community-Dwelling Older Black Men.

Marron MM, Harris TB, Boudreau RM, Clish CB, Moore SC, Murphy RA, Murthy VL, Sanders JL, Shah RV, Tseng GC, Wendell SG, Zmuda JM, Newman AB.

Metabolites. 2019 Apr 30;9(5). pii: E83. doi: 10.3390/metabo9050083.


Longitudinal changes in hip geometry in relation to the final menstrual period: Study of Women's Health Across the Nation (SWAN).

Nagaraj N, Boudreau RM, Danielson ME, Greendale GA, Karlamangla AS, Beck TJ, Cauley JA.

Bone. 2019 May;122:237-245. doi: 10.1016/j.bone.2019.02.016. Epub 2019 Mar 3.


A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity.

Marron MM, Miljkovic I, Boudreau RM, Christensen K, Feitosa MF, Lee JH, Sebastiani P, Thyagarajan B, Wojczynski MK, Zmuda JM, Newman AB; Long Life Family Study.

Metabolism. 2019 May;94:28-38. doi: 10.1016/j.metabol.2019.01.010. Epub 2019 Jan 30.


A multi-interpenetrating network (IPN) hydrogel with gelatin and silk fibroin.

Park S, Edwards S, Hou S, Boudreau R, Yee R, Jeong KJ.

Biomater Sci. 2019 Mar 26;7(4):1276-1280. doi: 10.1039/c8bm01532e.


Fluctuating Physical Function and Health: Their Role at the End of Life.

Lunney JR, Albert SM, Boudreau R, Ives D, Newman AB, Harris T.

J Palliat Med. 2019 Apr;22(4):424-426. doi: 10.1089/jpm.2018.0289. Epub 2018 Dec 20.


Neural correlates of perceived physical and mental fatigability in older adults: A pilot study.

Wasson E, Rosso AL, Santanasto AJ, Rosano C, Butters MA, Rejeski WJ, Boudreau RM, Aizenstein H, Gmelin T, Glynn NW; LIFE Study Group.

Exp Gerontol. 2019 Jan;115:139-147. doi: 10.1016/j.exger.2018.12.003. Epub 2018 Dec 4.


Do Autopsies Still Matter? The Influence of Autopsy Data on Final Injury Severity Score Calculations.

Boudreau RM, O'Neal E, Besl KM, Gordon SJ, Ralston W, Elterman JB, Pritts TA, Robinson BRH.

J Surg Res. 2019 Jan;233:453-458. doi: 10.1016/j.jss.2018.08.040. Epub 2018 Sep 22.


Prehospital Tranexamic Acid Administration During Aeromedical Transport After Injury.

Boudreau RM, Deshpande KK, Day GM, Hinckley WR, Harger N, Pritts TA, Makley AT, Goodman MD.

J Surg Res. 2019 Jan;233:132-138. doi: 10.1016/j.jss.2018.07.074. Epub 2018 Aug 21.


Normative Values of Muscle Power using Force Plate Jump Tests in Men Aged 77-101 Years: The Osteoporotic Fractures in Men (MrOS) Study.

Strotmeyer ES, Winger ME, Cauley JA, Boudreau RM, Cusick D, Collins RF, Chalhoub D, Buehring B, Orwoll E, Harris TB, Caserotti P.

J Nutr Health Aging. 2018;22(10):1167-1175. doi: 10.1007/s12603-018-1081-x.


Mobility and Vitality Lifestyle Program (MOVE UP): A Community Health Worker Intervention for Older Adults With Obesity to Improve Weight, Health, and Physical Function.

Venditti EM, Zgibor JC, Vander Bilt J, Kieffer LA, Boudreau RM, Burke LE, Glynn NW, Jakicic JM, Smith KJ, Semler LN, Rager JR, Albert SM, Newman AB.

Innov Aging. 2018 Jun 18;2(2):igy012. doi: 10.1093/geroni/igy012. eCollection 2018 Jun.


When Knowing "Enough" May Still Not Be Enough.

Matkovich SJ, Boudreau RL.

Circ Res. 2018 Aug 3;123(4):412-414. doi: 10.1161/CIRCRESAHA.118.313387. No abstract available.


How Well Does the Family Longevity Selection Score Work: A Validation Test Using the Utah Population Database.

Arbeeva LS, Hanson HA, Arbeev KG, Kulminski AM, Stallard E, Ukraintseva SV, Wu D, Boudreau RM, Province MA, Smith KR, Yashin AI.

Front Public Health. 2018 Oct 1;6:277. doi: 10.3389/fpubh.2018.00277. eCollection 2018.


Low blood pressure levels for fall injuries in older adults: the Health, Aging and Body Composition Study.

Sagawa N, Marcum ZA, Boudreau RM, Hanlon JT, Albert SM, O'Hare C, Satterfield S, Schwartz AV, Vinik AI, Cauley JA, Harris TB, Newman AB, Strotmeyer ES; Health Aging Body Composition Study.

Eur J Ageing. 2018 Jan 19;15(3):321-330. doi: 10.1007/s10433-017-0449-9. eCollection 2018 Sep.


Genetics of Human Longevity From Incomplete Data: New Findings From the Long Life Family Study.

Yashin AI, Arbeev KG, Wu D, Arbeeva LS, Bagley O, Stallard E, Kulminski AM, Akushevich I, Fang F, Wojczynski MK, Christensen K, Newman AB, Boudreau RM, Province MA, Thielke S, Perls TT, An P, Elo I, Ukraintseva SV.

J Gerontol A Biol Sci Med Sci. 2018 Oct 8;73(11):1472-1481. doi: 10.1093/gerona/gly057.


Sphingolipids and Innate Immunity: A New Approach to Infection in the Post-Antibiotic Era?

Baker JE, Boudreau RM, Seitz AP, Caldwell CC, Gulbins E, Edwards MJ.

Surg Infect (Larchmt). 2018 Nov/Dec;19(8):792-803. doi: 10.1089/sur.2018.187. Epub 2018 Oct 2.


Racial Differences in Cause-Specific Mortality Between Community-Dwelling Older Black and White Adults.

Marron MM, Ives DG, Boudreau RM, Harris TB, Newman AB.

J Am Geriatr Soc. 2018 Oct;66(10):1980-1986. doi: 10.1111/jgs.15534. Epub 2018 Sep 12.


Targeting Calpain for Heart Failure Therapy: Implications From Multiple Murine Models.

Wang Y, Chen B, Huang CK, Guo A, Wu J, Zhang X, Chen R, Chen C, Kutschke W, Weiss RM, Boudreau RL, Margulies KB, Hong J, Song LS.

JACC Basic Transl Sci. 2018 Aug 28;3(4):503-517. doi: 10.1016/j.jacbts.2018.05.004. eCollection 2018 Aug.


Knee Osteoarthritis and the Risk of Medically Treated Injurious Falls Among Older Adults: A Community-Based US Cohort Study.

Barbour KE, Sagawa N, Boudreau RM, Winger ME, Cauley JA, Nevitt MC, Fujii T, Patel KV, Strotmeyer ES.

Arthritis Care Res (Hoboken). 2018 Aug 21. doi: 10.1002/acr.23725. [Epub ahead of print]


Remembering Our History.

Boudreau RG.

J Oral Maxillofac Surg. 2018 Oct;76(10):2044-2045. doi: 10.1016/j.joms.2018.05.035. Epub 2018 Jun 6. No abstract available.


Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency.

Stein CS, Jadiya P, Zhang X, McLendon JM, Abouassaly GM, Witmer NH, Anderson EJ, Elrod JW, Boudreau RL.

Cell Rep. 2018 Jun 26;23(13):3710-3720.e8. doi: 10.1016/j.celrep.2018.06.002.


Volumetric bone mineral density (vBMD), bone structure, and structural geometry among rural South Indian, US Caucasian, and Afro-Caribbean older men.

Jammy GR, Boudreau RM, Singh T, Sharma PK, Ensrud K, Zmuda JM, Reddy PS, Newman AB, Cauley JA.

Arch Osteoporos. 2018 May 22;13(1):60. doi: 10.1007/s11657-018-0473-1.


Mortality in Relation to Changes in a Healthy Aging Index: The Health, Aging and Body Composition Study.

O'Connell MDL, Marron MM, Boudreau RM, Canney M, Sanders JL, Kenny RA, Kritchevsky SB, Harris TB, Newman AB.

J Gerontol A Biol Sci Med Sci. 2018 May 4. doi: 10.1093/gerona/gly114. [Epub ahead of print]


Associations Between Lean Mass, Muscle Strength and Power, and Skeletal Size, Density and Strength in Older Men.

Chalhoub D, Boudreau R, Greenspan S, Newman AB, Zmuda J, Frank-Wilson AW, Nagaraj N, Hoffman AR, Lane NE, Stefanick ML, Barrett-Connor E, Dam T, Cawthon PM, Orwoll ES, Cauley JA; Osteoporotic Fractures in Men (MrOS) Study Research Group.

J Bone Miner Res. 2018 Sep;33(9):1612-1621. doi: 10.1002/jbmr.3458. Epub 2018 Jun 12.


Sphingolipids as targets for inhalation treatment of cystic fibrosis.

Becker KA, Riethmüller J, Seitz AP, Gardner A, Boudreau R, Kamler M, Kleuser B, Schuchman E, Caldwell CC, Edwards MJ, Grassmé H, Brodlie M, Gulbins E.

Adv Drug Deliv Rev. 2018 Aug;133:66-75. doi: 10.1016/j.addr.2018.04.015. Epub 2018 Apr 24. Review.


Association of Biomarker and Physiologic Indices With Mortality in Older Adults: Cardiovascular Health Study.

Sanders JL, Arnold AM, Boudreau RM, Hirsch CH, Kizer JR, Kaplan RC, Cappola AR, Cushman M, Jacob ME, Kritchevsky SB, Newman AB.

J Gerontol A Biol Sci Med Sci. 2019 Jan 1;74(1):114-120. doi: 10.1093/gerona/gly075.


Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.

Rosso AL, Metti AL, Glynn NW, Boudreau RM, Rejeski WJ, Bohnen N, Chen H, Johannsen NM, King AC, Manini TM, Pahor M, Studenski SA, Fragoso CAV, Rosano C; LIFE Study Group.

J Am Geriatr Soc. 2018 Jul;66(6):1172-1179. doi: 10.1111/jgs.15369. Epub 2018 Apr 10.


A common variant alters SCN5A-miR-24 interaction and associates with heart failure mortality.

Zhang X, Yoon JY, Morley M, McLendon JM, Mapuskar KA, Gutmann R, Mehdi H, Bloom HL, Dudley SC, Ellinor PT, Shalaby AA, Weiss R, Tang WHW, Moravec CS, Singh M, Taylor AL, Yancy CW, Feldman AM, McNamara DM, Irani K, Spitz DR, Breheny P, Margulies KB, London B, Boudreau RL.

J Clin Invest. 2018 Mar 1;128(3):1154-1163. doi: 10.1172/JCI95710. Epub 2018 Feb 19.


From Early Radiographic Knee Osteoarthritis to Joint Arthroplasty: Determinants of Structural Progression and Symptoms.

Roemer FW, Kwoh CK, Fujii T, Hannon MJ, Boudreau RM, Hunter DJ, Eckstein F, John MR, Guermazi A.

Arthritis Care Res (Hoboken). 2018 Dec;70(12):1778-1786. doi: 10.1002/acr.23545.


Mobility Trajectories at the End of Life: Comparing Clinical Condition and Latent Class Approaches.

Lunney JR, Albert SM, Boudreau R, Ives D, Satterfield S, Newman AB, Harris T; Health Aging and Body Composition Study.

J Am Geriatr Soc. 2018 Mar;66(3):503-508. doi: 10.1111/jgs.15224. Epub 2018 Jan 18.


Relationship of Coagulopathy and Platelet Dysfunction to Transfusion Needs After Traumatic Brain Injury.

Martin G, Shah D, Elson N, Boudreau R, Hanseman D, Pritts TA, Makley AT, Foreman B, Goodman MD.

Neurocrit Care. 2018 Jun;28(3):330-337. doi: 10.1007/s12028-017-0485-5.


The association of air pollutants and allergic and nonallergic rhinitis in chronic rhinosinusitis.

Mady LJ, Schwarzbach HL, Moore JA, Boudreau RM, Kaffenberger TM, Willson TJ, Lee SE.

Int Forum Allergy Rhinol. 2018 Mar;8(3):369-376. doi: 10.1002/alr.22060. Epub 2017 Dec 11.


Air pollutants may be environmental risk factors in chronic rhinosinusitis disease progression.

Mady LJ, Schwarzbach HL, Moore JA, Boudreau RM, Tripathy S, Kinnee E, Dodson ZM, Willson TJ, Clougherty JE, Lee SE.

Int Forum Allergy Rhinol. 2018 Mar;8(3):377-384. doi: 10.1002/alr.22052. Epub 2017 Dec 6. Erratum in: Int Forum Allergy Rhinol. 2018 Apr;8(4):553.


Three Year Functional Trajectories Among Old Age Survivors and Decedents: Dying Eliminates a Racial Disparity.

Lunney JR, Albert SM, Boudreau R, Ives D, Satterfield S, Newman AB, Harris T; Health ABC study.

J Gen Intern Med. 2018 Feb;33(2):177-181. doi: 10.1007/s11606-017-4232-6. Epub 2017 Dec 4.


Age, Race, and Gender Factors in Incident Disability.

Jacob ME, Marron MM, Boudreau RM, Odden MC, Arnold AM, Newman AB.

J Gerontol A Biol Sci Med Sci. 2018 Jan 16;73(2):194-197. doi: 10.1093/gerona/glx194.


The Next Best Thing in Cardiovascular Research: Highlights From the Basic Cardiovascular Sciences Scientific Sessions.

Boudreau RL.

J Am Heart Assoc. 2017 Sep 20;6(9). pii: e007245. doi: 10.1161/JAHA.117.007245. No abstract available.


Impact of Incident Heart Failure on Body Composition Over Time in the Health, Aging, and Body Composition Study Population.

Forman DE, Santanasto AJ, Boudreau R, Harris T, Kanaya AM, Satterfield S, Simonsick EM, Butler J, Kizer JR, Newman AB.

Circ Heart Fail. 2017 Sep;10(9). pii: e003915. doi: 10.1161/CIRCHEARTFAILURE.117.003915.


A novel healthy blood pressure phenotype in the Long Life Family Study.

Marron MM, Singh J, Boudreau RM, Christensen K, Cosentino S, Feitosa MF, Minster RL, Perls T, Schupf N, Sebastiani P, Ukraintseva S, Wojczynski MK, Newman AB.

J Hypertens. 2018 Jan;36(1):43-53. doi: 10.1097/HJH.0000000000001514.


Impact of tranexamic acid on coagulation and inflammation in murine models of traumatic brain injury and hemorrhage.

Boudreau RM, Johnson M, Veile R, Friend LA, Goetzman H, Pritts TA, Caldwell CC, Makley AT, Goodman MD.

J Surg Res. 2017 Jul;215:47-54. doi: 10.1016/j.jss.2017.03.031. Epub 2017 Apr 1.


Slowing gait and risk for cognitive impairment: The hippocampus as a shared neural substrate.

Rosso AL, Verghese J, Metti AL, Boudreau RM, Aizenstein HJ, Kritchevsky S, Harris T, Yaffe K, Satterfield S, Studenski S, Rosano C.

Neurology. 2017 Jul 25;89(4):336-342. doi: 10.1212/WNL.0000000000004153. Epub 2017 Jun 28.


Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults.

Best JR, Rosano C, Aizenstein HJ, Tian Q, Boudreau RM, Ayonayon HN, Satterfield S, Simonsick EM, Studenski S, Yaffe K, Liu-Ambrose T; Health, Aging and Body Composition Study.

Neurobiol Aging. 2017 Sep;57:153-161. doi: 10.1016/j.neurobiolaging.2017.05.023. Epub 2017 Jun 6.


Catechol-O-Methyltransferase Genotype and Gait Speed Changes over 10 Years in Older Adults.

Metti AL, Rosano C, Boudreau R, Massa R, Yaffe K, Satterfield S, Harris T, Rosso AL.

J Am Geriatr Soc. 2017 Sep;65(9):2016-2022. doi: 10.1111/jgs.14980. Epub 2017 Jun 22.


Decreased KCNE2 Expression Participates in the Development of Cardiac Hypertrophy by Regulation of Calcineurin-NFAT (Nuclear Factor of Activated T Cells) and Mitogen-Activated Protein Kinase Pathways.

Liu W, Deng J, Ding W, Wang G, Shen Y, Zheng J, Zhang X, Luo Y, Lv C, Wang Y, Chen L, Yan D, Boudreau RL, Song LS, Liu J.

Circ Heart Fail. 2017 Jun;10(6). pii: e003960. doi: 10.1161/CIRCHEARTFAILURE.117.003960. Retraction in: Circ Heart Fail. 2017 Nov;10 (11):.


Relationship between sensorimotor peripheral nerve function and indicators of cardiovascular autonomic function in older adults from the Health, Aging and Body Composition Study.

Lange-Maia BS, Newman AB, Jakicic JM, Cauley JA, Boudreau RM, Schwartz AV, Simonsick EM, Satterfield S, Vinik AI, Zivkovic S, Harris TB, Strotmeyer ES.

Exp Gerontol. 2017 Oct 1;96:38-45. doi: 10.1016/j.exger.2017.04.007. Epub 2017 Apr 22.


Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic.

Martin GE, Boudreau RM, Couch C, Becker KA, Edwards MJ, Caldwell CC, Gulbins E, Seitz A.

Biochimie. 2017 Oct;141:91-96. doi: 10.1016/j.biochi.2017.03.014. Epub 2017 Mar 21.


Cognitive Status, Gray Matter Atrophy, and Lower Orthostatic Blood Pressure in Older Adults.

O'Hare C, Kenny RA, Aizenstein H, Boudreau R, Newman A, Launer L, Satterfield S, Yaffe K, Rosano C; Health ABC Study.

J Alzheimers Dis. 2017;57(4):1239-1250. doi: 10.3233/JAD-161228.


Are Preferences for Aggressive Medical Treatment Associated with Healthcare Utilization in the Very Old?

Albert SM, Lunney JR, Ye L, Boudreau R, Ives D, Satterfield S, Kaplan CM, Waters T, Ayonayon HN, Rubin SM, Newman AB, Harris T.

J Palliat Med. 2017 Mar 23. doi: 10.1089/jpm.2016.0284. [Epub ahead of print]


Sex Steroid Hormones and Fracture in a Multiethnic Cohort of Women: The Women's Health Initiative Study (WHI).

Cauley JA, Danielson ME, Jammy GR, Bauer DC, Jackson R, Wactawski-Wende J, Chlebowski RT, Ensrud KE, Boudreau R.

J Clin Endocrinol Metab. 2017 May 1;102(5):1538-1547. doi: 10.1210/jc.2016-3589.


RNA Interference of Human α-Synuclein in Mouse.

Kim YC, Miller A, Lins LC, Han SW, Keiser MS, Boudreau RL, Davidson BL, Narayanan NS.

Front Neurol. 2017 Jan 31;8:13. doi: 10.3389/fneur.2017.00013. eCollection 2017.


Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.

Vikram A, Lewarchik CM, Yoon JY, Naqvi A, Kumar S, Morgan GM, Jacobs JS, Li Q, Kim YR, Kassan M, Liu J, Gabani M, Kumar A, Mehdi H, Zhu X, Guan X, Kutschke W, Zhang X, Boudreau RL, Dai S, Matasic DS, Jung SB, Margulies KB, Kumar V, Bachschmid MM, London B, Irani K.

Nat Med. 2017 Mar;23(3):361-367. doi: 10.1038/nm.4284. Epub 2017 Feb 13.

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