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Extending Cross Metathesis To Identify Selective HDAC Inhibitors: Synthesis, Biological Activities, and Modeling.

Bouchet S, Linot C, Ruzic D, Agbaba D, Fouchaq B, Roche J, Nikolic K, Blanquart C, Bertrand P.

ACS Med Chem Lett. 2019 May 9;10(6):863-868. doi: 10.1021/acsmedchemlett.8b00440. eCollection 2019 Jun 13.


Worldwide phylogeography and history of wheat genetic diversity.

Balfourier F, Bouchet S, Robert S, De Oliveira R, Rimbert H, Kitt J, Choulet F; International Wheat Genome Sequencing Consortium; BreedWheat Consortium, Paux E.

Sci Adv. 2019 May 29;5(5):eaav0536. doi: 10.1126/sciadv.aav0536. eCollection 2019 May.


Late Holocene volcanic and anthropogenic mercury deposition in the western Central Andes (Lake Chungará, Chile).

Guédron S, Tolu J, Brisset E, Sabatier P, Perrot V, Bouchet S, Develle AL, Bindler R, Cossa D, Fritz SC, Baker PA.

Sci Total Environ. 2019 Apr 20;662:903-914. doi: 10.1016/j.scitotenv.2019.01.294. Epub 2019 Jan 24.


Methanogens and Iron-Reducing Bacteria: the Overlooked Members of Mercury-Methylating Microbial Communities in Boreal Lakes.

Bravo AG, Peura S, Buck M, Ahmed O, Mateos-Rivera A, Herrero Ortega S, Schaefer JK, Bouchet S, Tolu J, Björn E, Bertilsson S.

Appl Environ Microbiol. 2018 Nov 15;84(23). pii: e01774-18. doi: 10.1128/AEM.01774-18. Print 2018 Dec 1.


Linking Microbial Activities and Low-Molecular-Weight Thiols to Hg Methylation in Biofilms and Periphyton from High-Altitude Tropical Lakes in the Bolivian Altiplano.

Bouchet S, Goñi-Urriza M, Monperrus M, Guyoneaud R, Fernandez P, Heredia C, Tessier E, Gassie C, Point D, Guédron S, Achá D, Amouroux D.

Environ Sci Technol. 2018 Sep 4;52(17):9758-9767. doi: 10.1021/acs.est.8b01885. Epub 2018 Aug 20.


Breakthrough invasive aspergillosis and diagnostic accuracy of serum galactomannan enzyme immune assay during acute myeloid leukemia induction chemotherapy with posaconazole prophylaxis.

Calmettes C, Gabriel F, Blanchard E, Servant V, Bouchet S, Kabore N, Forcade E, Leroyer C, Bidet A, Latrabe V, Leguay T, Vigouroux S, Tabrizi R, Breilh D, Accoceberry I, de Lara MT, Pigneux A, Milpied N, Dumas PY.

Oncotarget. 2018 Jun 1;9(42):26724-26736. doi: 10.18632/oncotarget.25477. eCollection 2018 Jun 1.


Mitochondrial OXPHOS influences immune cell fate: lessons from hematopoietic AIF-deficient and NDUFS4-deficient mouse models.

Bertaux A, Cabon L, Brunelle-Navas MN, Bouchet S, Nemazanyy I, Susin SA.

Cell Death Dis. 2018 May 22;9(6):581. doi: 10.1038/s41419-018-0583-0. No abstract available.


Population genomics of sorghum (Sorghum bicolor) across diverse agroclimatic zones of Niger.

Maina F, Bouchet S, Marla SR, Hu Z, Wang J, Mamadou A, Abdou M, Saïdou AA, Morris GP.

Genome. 2018 Apr;61(4):223-232. doi: 10.1139/gen-2017-0131. Epub 2018 Feb 12.


AIF loss deregulates hematopoiesis and reveals different adaptive metabolic responses in bone marrow cells and thymocytes.

Cabon L, Bertaux A, Brunelle-Navas MN, Nemazanyy I, Scourzic L, Delavallée L, Vela L, Baritaud M, Bouchet S, Lopez C, Quang Van V, Garbin K, Chateau D, Gilard F, Sarfati M, Mercher T, Bernard OA, Susin SA.

Cell Death Differ. 2018 May;25(5):983-1001. doi: 10.1038/s41418-017-0035-x. Epub 2018 Jan 11.


High throughput routine determination of 17 tyrosine kinase inhibitors by LC-MS/MS.

Merienne C, Rousset M, Ducint D, Castaing N, Titier K, Molimard M, Bouchet S.

J Pharm Biomed Anal. 2018 Feb 20;150:112-120. doi: 10.1016/j.jpba.2017.11.060. Epub 2017 Nov 28.


Mercury contamination level and speciation inventory in Lakes Titicaca & Uru-Uru (Bolivia): Current status and future trends.

Guédron S, Point D, Acha D, Bouchet S, Baya PA, Tessier E, Monperrus M, Molina CI, Groleau A, Chauvaud L, Thebault J, Amice E, Alanoca L, Duwig C, Uzu G, Lazzaro X, Bertrand A, Bertrand S, Barbraud C, Delord K, Gibon FM, Ibanez C, Flores M, Fernandez Saavedra P, Ezpinoza ME, Heredia C, Rocha F, Zepita C, Amouroux D.

Environ Pollut. 2017 Dec;231(Pt 1):262-270. doi: 10.1016/j.envpol.2017.08.009. Epub 2017 Aug 12.


Trough dabrafenib plasma concentrations can predict occurrence of adverse events requiring dose reduction in metastatic melanoma.

Rousset M, Dutriaux C, Bosco-Lévy P, Prey S, Pham-Ledard A, Dousset L, Gérard E, Bouchet S, Canal-Raffin M, Titier K, Molimard M.

Clin Chim Acta. 2017 Sep;472:26-29. doi: 10.1016/j.cca.2017.07.012. Epub 2017 Jul 12.


Increased Power To Dissect Adaptive Traits in Global Sorghum Diversity Using a Nested Association Mapping Population.

Bouchet S, Olatoye MO, Marla SR, Perumal R, Tesso T, Yu J, Tuinstra M, Morris GP.

Genetics. 2017 Jun;206(2):573-585. doi: 10.1534/genetics.116.198499.


Hemodialysis does not impact axitinib exposure: clinical case of a patient with metastatic renal cell carcinoma.

Thiery-Vuillemin A, Orillard E, Mouillet G, Calcagno F, Devillard N, Bouchet S, Royer B.

Cancer Chemother Pharmacol. 2017 Jun;79(6):1273-1276. doi: 10.1007/s00280-017-3320-y. Epub 2017 Apr 27.


Aldosterone and Vascular Mineralocorticoid Receptors in Murine Endotoxic and Human Septic Shock.

Fadel F, André-Grégoire G, Gravez B, Bauvois B, Bouchet S, Sierra-Ramos C, Polito A, Mansart A, Alvarez de la Rosa D, Annane D, Jaisser F.

Crit Care Med. 2017 Sep;45(9):e954-e962. doi: 10.1097/CCM.0000000000002462.


An UPLC-MS/MS method for the quantification of BRAF inhibitors (vemurafenib, dabrafenib) and MEK inhibitors (cobimetinib, trametinib, binimetinib) in human plasma. Application to treated melanoma patients.

Rousset M, Titier K, Bouchet S, Dutriaux C, Pham-Ledard A, Prey S, Canal-Raffin M, Molimard M.

Clin Chim Acta. 2017 Jul;470:8-13. doi: 10.1016/j.cca.2017.04.009. Epub 2017 Apr 12.


Correction to Role of Settling Particles on Mercury Methylation in the Oxic Water Column of Freshwater Systems.

Gascón Díez E, Loizeau JL, Cosio C, Bouchet S, Adatte T, Amouroux D, Bravo AG.

Environ Sci Technol. 2017 Mar 21;51(6):3594. doi: 10.1021/acs.est.7b00808. Epub 2017 Mar 6. No abstract available.


Molecular composition of organic matter controls methylmercury formation in boreal lakes.

Bravo AG, Bouchet S, Tolu J, Björn E, Mateos-Rivera A, Bertilsson S.

Nat Commun. 2017 Feb 9;8:14255. doi: 10.1038/ncomms14255.


Concomitant elevations of MMP-9, NGAL, proMMP-9/NGAL and neutrophil elastase in serum of smokers with chronic obstructive pulmonary disease.

Bchir S, Nasr HB, Bouchet S, Benzarti M, Garrouch A, Tabka Z, Susin S, Chahed K, Bauvois B.

J Cell Mol Med. 2017 Jul;21(7):1280-1291. doi: 10.1111/jcmm.13057. Epub 2016 Dec 22.


Association mapping for phenology and plant architecture in maize shows higher power for developmental traits compared with growth influenced traits.

Bouchet S, Bertin P, Presterl T, Jamin P, Coubriche D, Gouesnard B, Laborde J, Charcosset A.

Heredity (Edinb). 2017 Mar;118(3):249-259. doi: 10.1038/hdy.2016.88. Epub 2016 Nov 23.


Role of Settling Particles on Mercury Methylation in the Oxic Water Column of Freshwater Systems.

Gascón Díez E, Loizeau JL, Cosio C, Bouchet S, Adatte T, Amouroux D, Bravo AG.

Environ Sci Technol. 2016 Nov 1;50(21):11672-11679. Epub 2016 Oct 13. Erratum in: Environ Sci Technol. 2017 Mar 21;51(6):3594.


Late diagnosis of primary hyperoxaluria type III.

Richard E, Blouin JM, Harambat J, Llanas B, Bouchet S, Acquaviva C, de la Faille R.

Ann Clin Biochem. 2017 May;54(3):406-411. doi: 10.1177/0004563216677101. Epub 2017 Jan 10.


Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension.

Guignabert C, Phan C, Seferian A, Huertas A, Tu L, Thuillet R, Sattler C, Le Hiress M, Tamura Y, Jutant EM, Chaumais MC, Bouchet S, Manéglier B, Molimard M, Rousselot P, Sitbon O, Simonneau G, Montani D, Humbert M.

J Clin Invest. 2016 Sep 1;126(9):3207-18. doi: 10.1172/JCI86249. Epub 2016 Aug 2.


Mycophenolic Acid Pharmacokinetics and Relapse in Children with Steroid-Dependent Idiopathic Nephrotic Syndrome.

Tellier S, Dallocchio A, Guigonis V, Saint-Marcoux F, Llanas B, Ichay L, Bandin F, Godron A, Morin D, Brochard K, Gandia P, Bouchet S, Marquet P, Decramer S, Harambat J.

Clin J Am Soc Nephrol. 2016 Oct 7;11(10):1777-1782. doi: 10.2215/CJN.00320116. Epub 2016 Jul 21.


Fractionation and size-distribution of metal and metalloid contaminants in a polluted groundwater rich in dissolved organic matter.

Kozyatnyk I, Bouchet S, Björn E, Haglund P.

J Hazard Mater. 2016 Nov 15;318:194-202. doi: 10.1016/j.jhazmat.2016.07.024. Epub 2016 Jul 9.


A candidate gene approach of the calcineurin pathway to identify variants associated with clinical outcomes in renal transplantation.

Pouché L, Koitka M, Stojanova J, Woillard JB, Monchaud C, Villeneuve C, Essig M, Abraham J, Le Meur Y, Rerolle JP, Kamar N, Rostaing L, Merville P, Gandia P, Bouchet S, Petersen BS, Marquet P, Picard N.

Pharmacogenomics. 2016 Mar;17(4):375-91. doi: 10.2217/pgs.15.181. Epub 2016 Feb 19.


Relationship between imatinib trough concentration and outcomes in the treatment of advanced gastrointestinal stromal tumours in a real-life setting.

Bouchet S, Poulette S, Titier K, Moore N, Lassalle R, Abouelfath A, Italiano A, Chevreau C, Bompas E, Collard O, Duffaud F, Rios M, Cupissol D, Adenis A, Ray-Coquard I, Bouché O, Le Cesne A, Bui B, Blay JY, Molimard M.

Eur J Cancer. 2016 Apr;57:31-8. doi: 10.1016/j.ejca.2015.12.029. Epub 2016 Feb 4.


Effect of esomeprazole on the oral absorption of dasatinib in a patient with Philadelphia-positive acute lymphoblastic leukemia.

Pape E, Michel D, Scala-Bertola J, Schiestel T, Harlé A, Bouchet S, Contet A, Pochon C, Gambier N.

Br J Clin Pharmacol. 2016 Jun;81(6):1195-1196. doi: 10.1111/bcp.12895. Epub 2016 Mar 4. No abstract available.


The CNGRC-GG-D(KLAKLAK)2 peptide induces a caspase-independent, Ca2+-dependent death in human leukemic myeloid cells by targeting surface aminopeptidase N/CD13.

Bouchet S, Tang R, Fava F, Legrand O, Bauvois B.

Oncotarget. 2016 Apr 12;7(15):19445-67. doi: 10.18632/oncotarget.6523.


Population genomics of pearl millet (Pennisetum glaucum (L.) R. Br.): Comparative analysis of global accessions and Senegalese landraces.

Hu Z, Mbacké B, Perumal R, Guèye MC, Sy O, Bouchet S, Prasad PV, Morris GP.

BMC Genomics. 2015 Dec 9;16:1048. doi: 10.1186/s12864-015-2255-0.


Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates.

Zwick V, Nurisso A, Simões-Pires C, Bouchet S, Martinet N, Lehotzky A, Ovadi J, Cuendet M, Blanquart C, Bertrand P.

Bioorg Med Chem Lett. 2016 Jan 1;26(1):154-9. doi: 10.1016/j.bmcl.2015.11.011. Epub 2015 Nov 11.


Accumulation and Changes in Composition of Collagens in Subcutaneous Adipose Tissue After Bariatric Surgery.

Liu Y, Aron-Wisnewsky J, Marcelin G, Genser L, Le Naour G, Torcivia A, Bauvois B, Bouchet S, Pelloux V, Sasso M, Miette V, Tordjman J, Clément K.

J Clin Endocrinol Metab. 2016 Jan;101(1):293-304. doi: 10.1210/jc.2015-3348. Epub 2015 Nov 19.


Evolution and Determinants of Health-Related Quality-of-Life in Kidney Transplant Patients Over the First 3 Years After Transplantation.

Villeneuve C, Laroche ML, Essig M, Merville P, Kamar N, Coubret A, Lacroix I, Bouchet S, Fruit D, Marquet P, Rousseau A; EPIGREN study group.

Transplantation. 2016 Mar;100(3):640-7. doi: 10.1097/TP.0000000000000846.


High methylmercury production under ferruginous conditions in sediments impacted by sewage treatment plant discharges.

Bravo AG, Bouchet S, Guédron S, Amouroux D, Dominik J, Zopfi J.

Water Res. 2015 Sep 1;80:245-55. doi: 10.1016/j.watres.2015.04.039. Epub 2015 May 9.


Dent and Flint maize diversity panels reveal important genetic potential for increasing biomass production.

Rincent R, Nicolas S, Bouchet S, Altmann T, Brunel D, Revilla P, Malvar RA, Moreno-Gonzalez J, Campo L, Melchinger AE, Schipprack W, Bauer E, Schoen CC, Meyer N, Ouzunova M, Dubreuil P, Giauffret C, Madur D, Combes V, Dumas F, Bauland C, Jamin P, Laborde J, Flament P, Moreau L, Charcosset A.

Theor Appl Genet. 2014 Nov;127(11):2313-31. doi: 10.1007/s00122-014-2379-7. Epub 2014 Oct 10.


Propensity-based study of aminoglycoside nephrotoxicity in patients with severe sepsis or septic shock.

Picard W, Bazin F, Clouzeau B, Bui HN, Soulat M, Guilhon E, Vargas F, Hilbert G, Bouchet S, Gruson D, Moore N, Boyer A.

Antimicrob Agents Chemother. 2014 Dec;58(12):7468-74. doi: 10.1128/AAC.03750-14. Epub 2014 Oct 6.


Targeting CD13 (aminopeptidase-N) in turn downregulates ADAM17 by internalization in acute myeloid leukaemia cells.

Bouchet S, Tang R, Fava F, Legrand O, Bauvois B.

Oncotarget. 2014 Sep 30;5(18):8211-22.


Fate of mercury species in the coastal plume of the Adour River estuary (Bay of Biscay, SW France).

Sharif A, Monperrus M, Tessier E, Bouchet S, Pinaly H, Rodriguez-Gonzalez P, Maron P, Amouroux D.

Sci Total Environ. 2014 Oct 15;496:701-713. doi: 10.1016/j.scitotenv.2014.06.116. Epub 2014 Aug 1.


Pre-dose plasma concentration monitoring of mycophenolate mofetil in patients with autoimmune diseases.

Streicher C, Djabarouti S, Xuereb F, Lazaro E, Legeron R, Bouchet S, Greib C, Breilh D, Pellegrin JL, Viallard JF.

Br J Clin Pharmacol. 2014 Dec;78(6):1419-25. doi: 10.1111/bcp.12462.


Large-scale imatinib dose-concentration-effect study in CML patients under routine care conditions.

Gotta V, Bouchet S, Widmer N, Schuld P, Decosterd LA, Buclin T, Mahon FX, Csajka C, Molimard M.

Leuk Res. 2014 Jul;38(7):764-72. doi: 10.1016/j.leukres.2014.03.023. Epub 2014 Apr 26.


Adaptation of maize to temperate climates: mid-density genome-wide association genetics and diversity patterns reveal key genomic regions, with a major contribution of the Vgt2 (ZCN8) locus.

Bouchet S, Servin B, Bertin P, Madur D, Combes V, Dumas F, Brunel D, Laborde J, Charcosset A, Nicolas S.

PLoS One. 2013 Aug 30;8(8):e71377. doi: 10.1371/journal.pone.0071377. eCollection 2013.


Massive sorghum collection genotyped with SSR markers to enhance use of global genetic resources.

Billot C, Ramu P, Bouchet S, Chantereau J, Deu M, Gardes L, Noyer JL, Rami JF, Rivallan R, Li Y, Lu P, Wang T, Folkertsma RT, Arnaud E, Upadhyaya HD, Glaszmann JC, Hash CT.

PLoS One. 2013;8(4):e59714. doi: 10.1371/journal.pone.0059714. Epub 2013 Apr 2.


Aminoglycosides in septic shock: an overview, with specific consideration given to their nephrotoxic risk.

Boyer A, Gruson D, Bouchet S, Clouzeau B, Hoang-Nam B, Vargas F, Gilles H, Molimard M, Rogues AM, Moore N.

Drug Saf. 2013 Apr;36(4):217-30. doi: 10.1007/s40264-013-0031-0. Review.


p70S6 kinase is a target of the novel proteasome inhibitor 3,3'-diamino-4'-methoxyflavone during apoptosis in human myeloid tumor cells.

Piedfer M, Bouchet S, Tang R, Billard C, Dauzonne D, Bauvois B.

Biochim Biophys Acta. 2013 Jun;1833(6):1316-28. doi: 10.1016/j.bbamcr.2013.02.016. Epub 2013 Feb 26.

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