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Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage.

Bolderson E, Burgess JT, Li J, Gandhi NS, Boucher D, Croft LV, Beard S, Plowman JJ, Suraweera A, Adams MN, Naqi A, Zhang SD, Sinclair DA, O'Byrne KJ, Richard DJ.

Nat Commun. 2019 Dec 3;10(1):5501. doi: 10.1038/s41467-019-13167-5.


The structural details of the interaction of single-stranded DNA binding protein hSSB2 (NABP1/OBFC2A) with UV-damaged DNA.

Lawson T, El-Kamand S, Boucher D, Duong DC, Kariawasam R, Bonvin AMJJ, Richard DJ, Gamsjaeger R, Cubeddu L.

Proteins. 2020 Feb;88(2):319-326. doi: 10.1002/prot.25806. Epub 2019 Aug 30.


Redox Regulation in the Base Excision Repair Pathway: Old and New Players as Cancer Therapeutic Targets.

Rajapakse A, Suraweera A, Boucher D, Naqi A, O'Byrne K, Richard DJ, Croft LV.

Curr Med Chem. 2019 Apr 29. doi: 10.2174/0929867326666190430092732. [Epub ahead of print]


[The effect of a polarity intervention on the insomnia and anxiety in middle-aged Quebec women].

Lambert J, Ouellet N, Boucher D.

Rech Soins Infirm. 2019 Mar;(136):43-53. doi: 10.3917/rsi.136.0043. French.


MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.

Coll RC, Hill JR, Day CJ, Zamoshnikova A, Boucher D, Massey NL, Chitty JL, Fraser JA, Jennings MP, Robertson AAB, Schroder K.

Nat Chem Biol. 2019 Jun;15(6):556-559. doi: 10.1038/s41589-019-0277-7. Epub 2019 May 13.


Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3-dependent vs. -independent macrophage cell death and host colonization.

Murthy AMV, Sullivan MJ, Nhu NTK, Lo AW, Phan MD, Peters KM, Boucher D, Schroder K, Beatson SA, Ulett GC, Schembri MA, Sweet MJ.

FASEB J. 2019 Jun;33(6):7437-7450. doi: 10.1096/fj.201802100R. Epub 2019 Mar 14.


Divide to conquer: NLRP3 is activated on dispersed trans-Golgi network.

Chen KW, Boucher D, Broz P.

Cell Res. 2019 Mar;29(3):181-182. doi: 10.1038/s41422-018-0138-z. No abstract available.


Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome.

Ross C, Chan AH, Von Pein J, Boucher D, Schroder K.

Life Sci Alliance. 2018 Dec 6;1(6):e201800237. doi: 10.26508/lsa.201800237. eCollection 2018 Dec.


The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses.

Bierschenk D, Monteleone M, Moghaddas F, Baker PJ, Masters SL, Boucher D, Schroder K.

J Leukoc Biol. 2019 Feb;105(2):401-410. doi: 10.1002/JLB.MA0318-112RR. Epub 2018 Oct 4.


Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps.

Chen KW, Monteleone M, Boucher D, Sollberger G, Ramnath D, Condon ND, von Pein JB, Broz P, Sweet MJ, Schroder K.

Sci Immunol. 2018 Aug 24;3(26). pii: eaar6676. doi: 10.1126/sciimmunol.aar6676.


Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.

Monteleone M, Stanley AC, Chen KW, Brown DL, Bezbradica JS, von Pein JB, Holley CL, Boucher D, Shakespear MR, Kapetanovic R, Rolfes V, Sweet MJ, Stow JL, Schroder K.

Cell Rep. 2018 Aug 7;24(6):1425-1433. doi: 10.1016/j.celrep.2018.07.027.


Effects of Thiolate Ligation in Monoiron Hydrogenase (Hmd): Stability of the {Fe(CO)2}2+ Core with NNS Ligands.

Xie ZL, Pennington DL, Boucher DG, Lo J, Rose MJ.

Inorg Chem. 2018 Aug 20;57(16):10028-10039. doi: 10.1021/acs.inorgchem.8b01185. Epub 2018 Aug 2.


Microbial markers in colorectal cancer detection and/or prognosis.

Villéger R, Lopès A, Veziant J, Gagnière J, Barnich N, Billard E, Boucher D, Bonnet M.

World J Gastroenterol. 2018 Jun 14;24(22):2327-2347. doi: 10.3748/wjg.v24.i22.2327. Review.


Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion.

Chen KW, Lawlor KE, von Pein JB, Boucher D, Gerlic M, Croker BA, Bezbradica JS, Vince JE, Schroder K.

J Immunol. 2018 May 15;200(10):3341-3346. doi: 10.4049/jimmunol.1701620. Epub 2018 Apr 16.


Current and projected cumulative impacts of fire, drought, and insects on timber volumes across Canada.

Boucher D, Boulanger Y, Aubin I, Bernier PY, Beaudoin A, Guindon L, Gauthier S.

Ecol Appl. 2018 Jul;28(5):1245-1259. doi: 10.1002/eap.1724. Epub 2018 Jun 5.


Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.

Boucher D, Monteleone M, Coll RC, Chen KW, Ross CM, Teo JL, Gomez GA, Holley CL, Bierschenk D, Stacey KJ, Yap AS, Bezbradica JS, Schroder K.

J Exp Med. 2018 Mar 5;215(3):827-840. doi: 10.1084/jem.20172222. Epub 2018 Feb 6.


A regional assessment of white-tailed deer effects on plant invasion.

Averill KM, Mortensen DA, Smithwick EAH, Kalisz S, McShea WJ, Bourg NA, Parker JD, Royo AA, Abrams MD, Apsley DK, Blossey B, Boucher DH, Caraher KL, DiTommaso A, Johnson SE, Masson R, Nuzzo VA.

AoB Plants. 2017 Dec 7;10(1):plx047. doi: 10.1093/aobpla/plx047. eCollection 2018 Feb.


Quantifying Caspase-1 Activity in Murine Macrophages.

Boucher D, Chan A, Ross C, Schroder K.

Methods Mol Biol. 2018;1725:163-176. doi: 10.1007/978-1-4939-7568-6_14.


Proof of Principle for Local Delivery of a c-Met Inhibitor.

Li H, Kadiyala I, Briggs M, Shawgo R, Reda K, Patel R, Tanner K, Berlioz-Seux F, Furey B, Hurter P, Boucher DM.

J Pharm Sci. 2018 Mar;107(3):856-862. doi: 10.1016/j.xphs.2017.10.025. Epub 2017 Oct 26.


Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib).

Germann UA, Furey BF, Markland W, Hoover RR, Aronov AM, Roix JJ, Hale M, Boucher DM, Sorrell DA, Martinez-Botella G, Fitzgibbon M, Shapiro P, Wick MJ, Samadani R, Meshaw K, Groover A, DeCrescenzo G, Namchuk M, Emery CM, Saha S, Welsch DJ.

Mol Cancer Ther. 2017 Nov;16(11):2351-2363. doi: 10.1158/1535-7163.MCT-17-0456. Epub 2017 Sep 22.


A Functional Approach to Solubility Parameter Computations.

Howell J, Roesing M, Boucher D.

J Phys Chem B. 2017 Apr 27;121(16):4191-4201. doi: 10.1021/acs.jpcb.7b01537. Epub 2017 Apr 18.


Trichinella Nativa Outbreak With Rare Thrombotic Complications Associated With Meat From a Black Bear Hunted in Northern Ontario.

Dalcin D, Zarlenga DS, Larter NC, Hoberg E, Boucher DA, Merrifield S, Lau R, Ralevski F, Cheema K, Schwartz KL, Boggild AK.

Clin Infect Dis. 2017 May 15;64(10):1367-1373. doi: 10.1093/cid/cix165. Erratum in: Clin Infect Dis. 2017 Aug 15;65(4):706.


Ssb1 and Ssb2 cooperate to regulate mouse hematopoietic stem and progenitor cells by resolving replicative stress.

Shi W, Vu T, Boucher D, Biernacka A, Nde J, Pandita RK, Straube J, Boyle GM, Al-Ejeh F, Nag P, Jeffery J, Harris JL, Bain AL, Grzelak M, Skrzypczak M, Mitra A, Dojer N, Crosetto N, Cloonan N, Becherel OJ, Finnie J, Skaar JR, Walkley CR, Pandita TK, Rowicka M, Ginalski K, Lane SW, Khanna KK.

Blood. 2017 May 4;129(18):2479-2492. doi: 10.1182/blood-2016-06-725093. Epub 2017 Mar 7.


Efficacy of school-based interventions aimed at decreasing sugar-sweetened beverage consumption among adolescents: a systematic review.

Vézina-Im LA, Beaulieu D, Bélanger-Gravel A, Boucher D, Sirois C, Dugas M, Provencher V.

Public Health Nutr. 2017 Sep;20(13):2416-2431. doi: 10.1017/S1368980017000076. Epub 2017 Feb 8. Review.


Salmonella-induced inflammasome activation in humans.

Bierschenk D, Boucher D, Schroder K.

Mol Immunol. 2017 Jun;86:38-43. doi: 10.1016/j.molimm.2016.11.009. Epub 2016 Dec 11. Review.


Solubility Characteristics of PCBM and C60.

Boucher D, Howell J.

J Phys Chem B. 2016 Nov 10;120(44):11556-11566. Epub 2016 Oct 26.


Nucleophosmin: from structure and function to disease development.

Box JK, Paquet N, Adams MN, Boucher D, Bolderson E, O'Byrne KJ, Richard DJ.

BMC Mol Biol. 2016 Aug 24;17(1):19. doi: 10.1186/s12867-016-0073-9. Review.


Oral exposure to environmental pollutant benzo[a]pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model.

Ribière C, Peyret P, Parisot N, Darcha C, Déchelotte PJ, Barnich N, Peyretaillade E, Boucher D.

Sci Rep. 2016 Aug 9;6:31027. doi: 10.1038/srep31027.


Prospective Study of Repeated Biopsy Feasibility and Acquired Resistance at Disease Progression in Patients With Advanced EGFR Mutant Lung Cancer Treated With Erlotinib in a Phase 2 Trial.

Redig AJ, Costa DB, Taibi M, Boucher D, Johnson BE, Jänne PA, Jackman DM.

JAMA Oncol. 2016 Sep 1;2(9):1240-2. doi: 10.1001/jamaoncol.2016.1304. No abstract available.


A Prospective Evaluation of Circulating Tumor Cells and Cell-Free DNA in EGFR-Mutant Non-Small Cell Lung Cancer Patients Treated with Erlotinib on a Phase II Trial.

Yanagita M, Redig AJ, Paweletz CP, Dahlberg SE, O'Connell A, Feeney N, Taibi M, Boucher D, Oxnard GR, Johnson BE, Costa DB, Jackman DM, Jänne PA.

Clin Cancer Res. 2016 Dec 15;22(24):6010-6020. Epub 2016 Jun 8.


Metabolic response of lung cancer cells to radiation in a paper-based 3D cell culture system.

Simon KA, Mosadegh B, Minn KT, Lockett MR, Mohammady MR, Boucher DM, Hall AB, Hillier SM, Udagawa T, Eustace BK, Whitesides GM.

Biomaterials. 2016 Jul;95:47-59. doi: 10.1016/j.biomaterials.2016.03.002. Epub 2016 Mar 3.


The influence of golf shaft stiffness on grip and clubhead kinematics.

MacKenzie SJ, Boucher DE.

J Sports Sci. 2017 Jan;35(2):105-111. Epub 2016 Mar 11.


Targeted Gene Capture by Hybridization to Illuminate Ecosystem Functioning.

Ribière C, Beugnot R, Parisot N, Gasc C, Defois C, Denonfoux J, Boucher D, Peyretaillade E, Peyret P.

Methods Mol Biol. 2016;1399:167-82. doi: 10.1007/978-1-4939-3369-3_10.


Distribution of Dehalococcoidia in the Anaerobic Deep Water of a Remote Meromictic Crater Lake and Detection of Dehalococcoidia-Derived Reductive Dehalogenase Homologous Genes.

Biderre-Petit C, Dugat-Bony E, Mege M, Parisot N, Adrian L, Moné A, Denonfoux J, Peyretaillade E, Debroas D, Boucher D, Peyret P.

PLoS One. 2016 Jan 6;11(1):e0145558. doi: 10.1371/journal.pone.0145558. eCollection 2016.


Development and characterization of an αvβ6-specific diabody and a disulfide-stabilized αvβ6-specific cys-diabody.

White JB, Boucher DL, Zettlitz KA, Wu AM, Sutcliffe JL.

Nucl Med Biol. 2015 Dec;42(12):945-57. doi: 10.1016/j.nucmedbio.2015.07.014. Epub 2015 Aug 4.


NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.

Baker PJ, Boucher D, Bierschenk D, Tebartz C, Whitney PG, D'Silva DB, Tanzer MC, Monteleone M, Robertson AA, Cooper MA, Alvarez-Diaz S, Herold MJ, Bedoui S, Schroder K, Masters SL.

Eur J Immunol. 2015 Oct;45(10):2918-26. doi: 10.1002/eji.201545655. Epub 2015 Aug 24.


Capturing prokaryotic dark matter genomes.

Gasc C, Ribière C, Parisot N, Beugnot R, Defois C, Petit-Biderre C, Boucher D, Peyretaillade E, Peyret P.

Res Microbiol. 2015 Dec;166(10):814-30. doi: 10.1016/j.resmic.2015.06.001. Epub 2015 Jun 20. Review.


Effect of an intervention mapping approach to promote the consumption of fruits and vegetables among young adults in junior college: A quasi-experimental study.

Boucher D, Gagné C, Côté F.

Psychol Health. 2015;30(11):1306-25. doi: 10.1080/08870446.2015.1050393. Epub 2015 Jun 19.


Ssb2/Nabp1 is dispensable for thymic maturation, male fertility, and DNA repair in mice.

Boucher D, Vu T, Bain AL, Tagliaro-Jahns M, Shi W, Lane SW, Khanna KK.

FASEB J. 2015 Aug;29(8):3326-34. doi: 10.1096/fj.14-269944. Epub 2015 Apr 27.


A paper-based invasion assay: assessing chemotaxis of cancer cells in gradients of oxygen.

Mosadegh B, Lockett MR, Minn KT, Simon KA, Gilbert K, Hillier S, Newsome D, Li H, Hall AB, Boucher DM, Eustace BK, Whitesides GM.

Biomaterials. 2015 Jun;52:262-71. doi: 10.1016/j.biomaterials.2015.02.012. Epub 2015 Feb 28.


Exploiting the architecture and the features of the microsporidian genomes to investigate diversity and impact of these parasites on ecosystems.

Peyretaillade E, Boucher D, Parisot N, Gasc C, Butler R, Pombert JF, Lerat E, Peyret P.

Heredity (Edinb). 2015 May;114(5):441-9. doi: 10.1038/hdy.2014.78. Epub 2014 Sep 3. Review.


Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970.

Hall AB, Newsome D, Wang Y, Boucher DM, Eustace B, Gu Y, Hare B, Johnson MA, Milton S, Murphy CE, Takemoto D, Tolman C, Wood M, Charlton P, Charrier JD, Furey B, Golec J, Reaper PM, Pollard JR.

Oncotarget. 2014 Jul 30;5(14):5674-85.


Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human.

Kielar M, Tuy FP, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, Oegema R, Mancini GM, Bahi-Buisson N, Olaso R, Le Moing AG, Boutourlinsky K, Boucher D, Carpentier W, Berquin P, Deleuze JF, Belvindrah R, Borrell V, Welker E, Chelly J, Croquelois A, Francis F.

Nat Neurosci. 2014 Jul;17(7):923-33. doi: 10.1038/nn.3729. Epub 2014 May 25.


PhylOPDb: a 16S rRNA oligonucleotide probe database for prokaryotic identification.

Jaziri F, Parisot N, Abid A, Denonfoux J, Ribière C, Gasc C, Boucher D, Brugère JF, Mahul A, Hill DR, Peyretaillade E, Peyret P.

Database (Oxford). 2014 Apr 26;2014(0):bau036. doi: 10.1093/database/bau036. Print 2014.


General in vitro caspase assay procedures.

Boucher D, Duclos C, Denault JB.

Methods Mol Biol. 2014;1133:3-39. doi: 10.1007/978-1-4939-0357-3_1.


Success and failure rates of tumor genotyping techniques in routine pathological samples with non-small-cell lung cancer.

Vanderlaan PA, Yamaguchi N, Folch E, Boucher DH, Kent MS, Gangadharan SP, Majid A, Goldstein MA, Huberman MS, Kocher ON, Costa DB.

Lung Cancer. 2014 Apr;84(1):39-44. doi: 10.1016/j.lungcan.2014.01.013. Epub 2014 Jan 28.


Adequacy of lymph node transbronchial needle aspirates using convex probe endobronchial ultrasound for multiple tumor genotyping techniques in non-small-cell lung cancer.

Folch E, Yamaguchi N, VanderLaan PA, Kocher ON, Boucher DH, Goldstein MA, Huberman MS, Kent MS, Gangadharan SP, Costa DB, Majid A.

J Thorac Oncol. 2013 Nov;8(11):1438-1444. doi: 10.1097/JTO.0b013e3182a471a9.


Smoking status and self-reported race affect the frequency of clinically relevant oncogenic alterations in non-small-cell lung cancers at a United States-based academic medical practice.

Yamaguchi N, Vanderlaan PA, Folch E, Boucher DH, Canepa HM, Kent MS, Gangadharan SP, Majid A, Kocher ON, Goldstein MA, Huberman MS, Costa DB.

Lung Cancer. 2013 Oct;82(1):31-7. doi: 10.1016/j.lungcan.2013.07.013. Epub 2013 Aug 7.


Geographic distance and ecosystem size determine the distribution of smallest protists in lacustrine ecosystems.

Lepère C, Domaizon I, Taïb N, Mangot JF, Bronner G, Boucher D, Debroas D.

FEMS Microbiol Ecol. 2013 Jul;85(1):85-94. doi: 10.1111/1574-6941.12100. Epub 2013 Mar 18.

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